-
1
-
-
79960365945
-
Vascular endothelial growth factor-targeted therapies in advanced renal cell carcinoma
-
L. Albiges, M. Salem, B. Rini, and B. Escudier Vascular endothelial growth factor-targeted therapies in advanced renal cell carcinoma Hematol Oncol Clin North Am 25 2011 813 833
-
(2011)
Hematol Oncol Clin North Am
, vol.25
, pp. 813-833
-
-
Albiges, L.1
Salem, M.2
Rini, B.3
Escudier, B.4
-
2
-
-
58249095931
-
Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts
-
C. Anderberg, H. Li, L. Fredriksson, J. Andrae, C. Betsholtz, and X. Li Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts Cancer Res 69 2009 369 378
-
(2009)
Cancer Res
, vol.69
, pp. 369-378
-
-
Anderberg, C.1
Li, H.2
Fredriksson, L.3
Andrae, J.4
Betsholtz, C.5
Li, X.6
-
3
-
-
67349177262
-
Angiogenic markers show high prognostic impact on survival in marginally operable non-small cell lung cancer patients treated with adjuvant radiotherapy
-
S. Andersen, T. Donnem, S. Al-Saad, K. Al-Shibli, L.T. Busund, and R.M. Bremnes Angiogenic markers show high prognostic impact on survival in marginally operable non-small cell lung cancer patients treated with adjuvant radiotherapy J Thorac Oncol 4 2009 463 471
-
(2009)
J Thorac Oncol
, vol.4
, pp. 463-471
-
-
Andersen, S.1
Donnem, T.2
Al-Saad, S.3
Al-Shibli, K.4
Busund, L.T.5
Bremnes, R.M.6
-
4
-
-
0033981473
-
The plasminogen activation system in tumor growth, invasion, and metastasis
-
P.A. Andreasen, R. Egelund, and H.H. Petersen The plasminogen activation system in tumor growth, invasion, and metastasis Cell Mol Life Sci 57 2000 25 40
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 25-40
-
-
Andreasen, P.A.1
Egelund, R.2
Petersen, H.H.3
-
5
-
-
60949112215
-
CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth
-
M. Augsten, C. Hagglof, E. Olsson, C. Stolz, P. Tsagozis, and T. Levchenko CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth Proc Natl Acad Sci U S A 106 2009 3414 3419
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3414-3419
-
-
Augsten, M.1
Hagglof, C.2
Olsson, E.3
Stolz, C.4
Tsagozis, P.5
Levchenko, T.6
-
6
-
-
78649645713
-
A digest on the role of the tumor microenvironment in gastrointestinal cancers
-
M. Augsten, C. Hagglof, C. Pena, and A. Ostman A digest on the role of the tumor microenvironment in gastrointestinal cancers Cancer Microenviron 3 2010 167 176
-
(2010)
Cancer Microenviron
, vol.3
, pp. 167-176
-
-
Augsten, M.1
Hagglof, C.2
Pena, C.3
Ostman, A.4
-
7
-
-
73949125660
-
Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
-
M. Balsamo, F. Scordamaglia, G. Pietra, C. Manzini, C. Cantoni, and M. Boitano Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity Proc Natl Acad Sci U S A 106 2009 20847 20852
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 20847-20852
-
-
Balsamo, M.1
Scordamaglia, F.2
Pietra, G.3
Manzini, C.4
Cantoni, C.5
Boitano, M.6
-
8
-
-
77956425361
-
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
-
V. Barry-Hamilton, R. Spangler, D. Marshall, S. McCauley, H.M. Rodriguez, and M. Oyasu Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment Nat Med 16 2010 1009 1017
-
(2010)
Nat Med
, vol.16
, pp. 1009-1017
-
-
Barry-Hamilton, V.1
Spangler, R.2
Marshall, D.3
McCauley, S.4
Rodriguez, H.M.5
Oyasu, M.6
-
9
-
-
79955475569
-
A phase II, single-arm study of the anti-alpha5beta1 integrin antibody volociximab as monotherapy in patients with platinum-resistant advanced epithelial ovarian or primary peritoneal cancer
-
K.M. Bell-McGuinn, C.M. Matthews, S.N. Ho, M. Barve, L. Gilbert, and R.T. Penson A phase II, single-arm study of the anti-alpha5beta1 integrin antibody volociximab as monotherapy in patients with platinum-resistant advanced epithelial ovarian or primary peritoneal cancer Gynecol Oncol 121 2011 273 279
-
(2011)
Gynecol Oncol
, vol.121
, pp. 273-279
-
-
Bell-Mcguinn, K.M.1
Matthews, C.M.2
Ho, S.N.3
Barve, M.4
Gilbert, L.5
Penson, R.T.6
-
10
-
-
25144437350
-
A6, a urokinase plasminogen activator (uPA)-derived peptide in patients with advanced gynecologic cancer: A phase i trial
-
A. Berkenblit, U.A. Matulonis, J.F. Kroener, B.J. Dezube, G.N. Lam, and L.C. Cuasay A6, a urokinase plasminogen activator (uPA)-derived peptide in patients with advanced gynecologic cancer: a phase I trial Gynecol Oncol 99 2005 50 57
-
(2005)
Gynecol Oncol
, vol.99
, pp. 50-57
-
-
Berkenblit, A.1
Matulonis, U.A.2
Kroener, J.F.3
Dezube, B.J.4
Lam, G.N.5
Cuasay, L.C.6
-
11
-
-
33748196958
-
Celecoxib for the prevention of sporadic colorectal adenomas
-
M.M. Bertagnolli, C.J. Eagle, A.G. Zauber, M. Redston, S.D. Solomon, and K. Kim Celecoxib for the prevention of sporadic colorectal adenomas N Engl J Med 355 2006 873 884
-
(2006)
N Engl J Med
, vol.355
, pp. 873-884
-
-
Bertagnolli, M.M.1
Eagle, C.J.2
Zauber, A.G.3
Redston, M.4
Solomon, S.D.5
Kim, K.6
-
14
-
-
0037457657
-
Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells
-
C. Bisson, S. Blacher, M. Polette, J.F. Blanc, F. Kebers, and J. Desreux Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells Int J Cancer 105 2003 7 13
-
(2003)
Int J Cancer
, vol.105
, pp. 7-13
-
-
Bisson, C.1
Blacher, S.2
Polette, M.3
Blanc, J.F.4
Kebers, F.5
Desreux, J.6
-
15
-
-
79951602633
-
Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: Results of a randomized and controlled phase IIb study
-
U. Bogdahn, P. Hau, G. Stockhammer, N.K. Venkataramana, A.K. Mahapatra, and A. Suri Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study Neuro Oncol 13 2011 132 142
-
(2011)
Neuro Oncol
, vol.13
, pp. 132-142
-
-
Bogdahn, U.1
Hau, P.2
Stockhammer, G.3
Venkataramana, N.K.4
Mahapatra, A.K.5
Suri, A.6
-
16
-
-
77956301181
-
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion
-
D. Bourboulia, and W.G. Stetler-Stevenson Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): positive and negative regulators in tumor cell adhesion Semin Cancer Biol 20 2010 161 168
-
(2010)
Semin Cancer Biol
, vol.20
, pp. 161-168
-
-
Bourboulia, D.1
Stetler-Stevenson, W.G.2
-
17
-
-
78651073833
-
The role of tumor stroma in cancer progression and prognosis: Emphasis on carcinoma-associated fibroblasts and non-small cell lung cancer
-
R.M. Bremnes, T. Donnem, S. Al-Saad, K. Al-Shibli, S. Andersen, and R. Sirera The role of tumor stroma in cancer progression and prognosis: emphasis on carcinoma-associated fibroblasts and non-small cell lung cancer J Thorac Oncol 6 2011 209 217
-
(2011)
J Thorac Oncol
, vol.6
, pp. 209-217
-
-
Bremnes, R.M.1
Donnem, T.2
Al-Saad, S.3
Al-Shibli, K.4
Andersen, S.5
Sirera, R.6
-
18
-
-
0037017835
-
Inhibition of the alpha-nu integrins with a cyclic RGD peptide impairs angiogenesis, growth and metastasis of solid tumours in vivo
-
M.A. Buerkle, S.A. Pahernik, A. Sutter, A. Jonczyk, K. Messmer, and M. Dellian Inhibition of the alpha-nu integrins with a cyclic RGD peptide impairs angiogenesis, growth and metastasis of solid tumours in vivo Br J Cancer 86 2002 788 795
-
(2002)
Br J Cancer
, vol.86
, pp. 788-795
-
-
Buerkle, M.A.1
Pahernik, S.A.2
Sutter, A.3
Jonczyk, A.4
Messmer, K.5
Dellian, M.6
-
19
-
-
77951953778
-
Epithelial-mesenchymal transition: From molecular mechanisms, redox regulation to implications in human health and disease
-
S. Cannito, E. Novo, L.V. di Bonzo, C. Busletta, S. Colombatto, and M. Parola Epithelial-mesenchymal transition: from molecular mechanisms, redox regulation to implications in human health and disease Antioxid Redox Signal 12 2010 1383 1430
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 1383-1430
-
-
Cannito, S.1
Novo, E.2
Di Bonzo, L.V.3
Busletta, C.4
Colombatto, S.5
Parola, M.6
-
20
-
-
1642326689
-
Comparative evaluation of FGF-2-, VEGF-A-, and VEGF-C-induced angiogenesis, lymphangiogenesis, vascular fenestrations, and permeability
-
R. Cao, A. Eriksson, H. Kubo, K. Alitalo, Y. Cao, and J. Thyberg Comparative evaluation of FGF-2-, VEGF-A-, and VEGF-C-induced angiogenesis, lymphangiogenesis, vascular fenestrations, and permeability Circ Res 94 2004 664 670
-
(2004)
Circ Res
, vol.94
, pp. 664-670
-
-
Cao, R.1
Eriksson, A.2
Kubo, H.3
Alitalo, K.4
Cao, Y.5
Thyberg, J.6
-
21
-
-
0142188716
-
CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin
-
A.R. Cardones, T. Murakami, and S.T. Hwang CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin Cancer Res 63 2003 6751 6757
-
(2003)
Cancer Res
, vol.63
, pp. 6751-6757
-
-
Cardones, A.R.1
Murakami, T.2
Hwang, S.T.3
-
22
-
-
77952986190
-
Integrins as target: First phase III trial launches, but questions remain
-
A. Carter Integrins as target: first phase III trial launches, but questions remain J Natl Cancer Inst 102 2010 675 677
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 675-677
-
-
Carter, A.1
-
23
-
-
80755184801
-
COX-derived prostanoid pathways in gastrointestinal cancer development and progression: Novel targets for prevention and intervention
-
M.C. Cathcart, K.J. O'Byrne, J.V. Reynolds, J. O'Sullivan, and G.P. Pidgeon COX-derived prostanoid pathways in gastrointestinal cancer development and progression: novel targets for prevention and intervention Biochim Biophys Acta 1825 2012 49 63
-
(2012)
Biochim Biophys Acta
, vol.1825
, pp. 49-63
-
-
Cathcart, M.C.1
O'Byrne, K.J.2
Reynolds, J.V.3
O'Sullivan, J.4
Pidgeon, G.P.5
-
24
-
-
33846018363
-
Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV
-
V.J. Christiansen, K.W. Jackson, K.N. Lee, and P.A. McKee Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV Arch Biochem Biophys 457 2007 177 186
-
(2007)
Arch Biochem Biophys
, vol.457
, pp. 177-186
-
-
Christiansen, V.J.1
Jackson, K.W.2
Lee, K.N.3
McKee, P.A.4
-
25
-
-
67449098972
-
Alpha-smooth muscle actin-positive fibroblasts promote biliary cell proliferation and correlate with poor survival in cholangiocarcinoma
-
C. Chuaysri, P. Thuwajit, A. Paupairoj, S. Chau-In, T. Suthiphongchai, and C. Thuwajit Alpha-smooth muscle actin-positive fibroblasts promote biliary cell proliferation and correlate with poor survival in cholangiocarcinoma Oncol Rep 21 2009 957 969
-
(2009)
Oncol Rep
, vol.21
, pp. 957-969
-
-
Chuaysri, C.1
Thuwajit, P.2
Paupairoj, A.3
Chau-In, S.4
Suthiphongchai, T.5
Thuwajit, C.6
-
26
-
-
84862313154
-
Cancer-associated-fibroblasts and tumour cells: A diabolic liaison driving cancer progression
-
P. Cirri, and P. Chiarugi Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression Cancer Metastasis Rev 31 2012 195 208
-
(2012)
Cancer Metastasis Rev
, vol.31
, pp. 195-208
-
-
Cirri, P.1
Chiarugi, P.2
-
27
-
-
79952771133
-
Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761
-
E.C. Connolly, E.F. Saunier, D. Quigley, M.T. Luu, A. De Sapio, and B. Hann Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761 Cancer Res 71 2011 2339 2349
-
(2011)
Cancer Res
, vol.71
, pp. 2339-2349
-
-
Connolly, E.C.1
Saunier, E.F.2
Quigley, D.3
Luu, M.T.4
De Sapio, A.5
Hann, B.6
-
28
-
-
77958153436
-
Fibroblast and prostate tumor cell cross-talk: Fibroblast differentiation, TGF-β, and extracellular matrix down-regulation
-
V.J. Coulson-Thomas, T.F. Gesteira, Y.M. Coulson-Thomas, C.M. Vicente, I.L. Tersariol, and H.B. Nader Fibroblast and prostate tumor cell cross-talk: fibroblast differentiation, TGF-β, and extracellular matrix down-regulation Exp Cell Res 316 2010 3207 3226
-
(2010)
Exp Cell Res
, vol.316
, pp. 3207-3226
-
-
Coulson-Thomas, V.J.1
Gesteira, T.F.2
Coulson-Thomas, Y.M.3
Vicente, C.M.4
Tersariol, I.L.5
Nader, H.B.6
-
29
-
-
57849106330
-
PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment
-
Y. Crawford, I. Kasman, L. Yu, C. Zhong, X. Wu, and Z. Modrusan PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment Cancer Cell 15 2009 21 34
-
(2009)
Cancer Cell
, vol.15
, pp. 21-34
-
-
Crawford, Y.1
Kasman, I.2
Yu, L.3
Zhong, C.4
Wu, X.5
Modrusan, Z.6
-
30
-
-
40649121508
-
Evolving role of uPA/uPAR system in human cancers
-
K. Dass, A. Ahmad, A.S. Azmi, S.H. Sarkar, and F.H. Sarkar Evolving role of uPA/uPAR system in human cancers Cancer Treat Rev 34 2008 122 136
-
(2008)
Cancer Treat Rev
, vol.34
, pp. 122-136
-
-
Dass, K.1
Ahmad, A.2
Azmi, A.S.3
Sarkar, S.H.4
Sarkar, F.H.5
-
31
-
-
70350450580
-
Phase III prospective randomized double-blind placebo-controlled trial of plerixafor plus granulocyte colony-stimulating factor compared with placebo plus granulocyte colony-stimulating factor for autologous stem-cell mobilization and transplantation for patients with non-Hodgkin's lymphoma
-
J.F. DiPersio, I.N. Micallef, P.J. Stiff, B.J. Bolwell, R.T. Maziarz, and E. Jacobsen Phase III prospective randomized double-blind placebo-controlled trial of plerixafor plus granulocyte colony-stimulating factor compared with placebo plus granulocyte colony-stimulating factor for autologous stem-cell mobilization and transplantation for patients with non-Hodgkin's lymphoma J Clin Oncol 27 2009 4767 4773
-
(2009)
J Clin Oncol
, vol.27
, pp. 4767-4773
-
-
Dipersio, J.F.1
Micallef, I.N.2
Stiff, P.J.3
Bolwell, B.J.4
Maziarz, R.T.5
Jacobsen, E.6
-
32
-
-
67651089936
-
Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma
-
J.F. DiPersio, E.A. Stadtmauer, A. Nademanee, I.N. Micallef, P.J. Stiff, and J.L. Kaufman Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma Blood 113 2009 5720 5726
-
(2009)
Blood
, vol.113
, pp. 5720-5726
-
-
Dipersio, J.F.1
Stadtmauer, E.A.2
Nademanee, A.3
Micallef, I.N.4
Stiff, P.J.5
Kaufman, J.L.6
-
33
-
-
9244236047
-
Bone marrow contribution to tumor-associated myofibroblasts and fibroblasts
-
N.C. Direkze, K. Hodivala-Dilke, R. Jeffery, T. Hunt, R. Poulsom, and D. Oukrif Bone marrow contribution to tumor-associated myofibroblasts and fibroblasts Cancer Res 64 2004 8492 8495
-
(2004)
Cancer Res
, vol.64
, pp. 8492-8495
-
-
Direkze, N.C.1
Hodivala-Dilke, K.2
Jeffery, R.3
Hunt, T.4
Poulsom, R.5
Oukrif, D.6
-
34
-
-
3543002277
-
VEGF-null cells require PDGFR alpha signaling-mediated stromal fibroblast recruitment for tumorigenesis
-
J. Dong, J. Grunstein, M. Tejada, F. Peale, G. Frantz, and W.C. Liang VEGF-null cells require PDGFR alpha signaling-mediated stromal fibroblast recruitment for tumorigenesis EMBO J 23 2004 2800 2810
-
(2004)
EMBO J
, vol.23
, pp. 2800-2810
-
-
Dong, J.1
Grunstein, J.2
Tejada, M.3
Peale, F.4
Frantz, G.5
Liang, W.C.6
-
35
-
-
79954606458
-
CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: An emerging sensitizer for anticancer therapies?
-
D.G. Duda, S.V. Kozin, N.D. Kirkpatrick, L. Xu, D. Fukumura, and R.K. Jain CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies? Clin Cancer Res 17 2011 2074 2080
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2074-2080
-
-
Duda, D.G.1
Kozin, S.V.2
Kirkpatrick, N.D.3
Xu, L.4
Fukumura, D.5
Jain, R.K.6
-
36
-
-
0347917028
-
The urokinase plasminogen activator system: Role in malignancy
-
M.J. Duffy The urokinase plasminogen activator system: role in malignancy Curr Pharm Des 10 2004 39 49
-
(2004)
Curr Pharm des
, vol.10
, pp. 39-49
-
-
Duffy, M.J.1
-
37
-
-
77956251071
-
Antagonistic anti-urokinase plasminogen activator receptor (uPAR) antibodies significantly inhibit uPAR-mediated cellular signaling and migration
-
S. Duriseti, D.H. Goetz, D.R. Hostetter, A.M. LeBeau, Y. Wei, and C.S. Craik Antagonistic anti-urokinase plasminogen activator receptor (uPAR) antibodies significantly inhibit uPAR-mediated cellular signaling and migration J Biol Chem 285 2010 26878 26888
-
(2010)
J Biol Chem
, vol.285
, pp. 26878-26888
-
-
Duriseti, S.1
Goetz, D.H.2
Hostetter, D.R.3
Lebeau, A.M.4
Wei, Y.5
Craik, C.S.6
-
38
-
-
0032940051
-
Phase i and pharmacologic study of the tyrosine kinase inhibitor SU101 in patients with advanced solid tumors
-
S.G. Eckhardt, J. Rizzo, K.R. Sweeney, G. Cropp, S.D. Baker, and M.A. Kraynak Phase I and pharmacologic study of the tyrosine kinase inhibitor SU101 in patients with advanced solid tumors J Clin Oncol 17 1999 1095 1104
-
(1999)
J Clin Oncol
, vol.17
, pp. 1095-1104
-
-
Eckhardt, S.G.1
Rizzo, J.2
Sweeney, K.R.3
Cropp, G.4
Baker, S.D.5
Kraynak, M.A.6
-
39
-
-
81155126448
-
Interaction of celecoxib with different anti-cancer drugs is antagonistic in breast but not in other cancer cells
-
R.A. El-Awady, E.M. Saleh, M. Ezz, and A.M. Elsayed Interaction of celecoxib with different anti-cancer drugs is antagonistic in breast but not in other cancer cells Toxicol Appl Pharmacol 255 2011 271 286
-
(2011)
Toxicol Appl Pharmacol
, vol.255
, pp. 271-286
-
-
El-Awady, R.A.1
Saleh, E.M.2
Ezz, M.3
Elsayed, A.M.4
-
40
-
-
76349096670
-
Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner
-
N. Erez, M. Truitt, P. Olson, S.T. Arron, and D. Hanahan Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner Cancer Cell 17 2010 135 147
-
(2010)
Cancer Cell
, vol.17
, pp. 135-147
-
-
Erez, N.1
Truitt, M.2
Olson, P.3
Arron, S.T.4
Hanahan, D.5
-
41
-
-
31544435739
-
Breast cancer DNA methylation profiles in cancer cells and tumor stroma: Association with HER-2/neu status in primary breast cancer
-
H. Fiegl, S. Millinger, G. Goebel, E. Muller-Holzner, C. Marth, and P.W. Laird Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer Cancer Res 66 2006 29 33
-
(2006)
Cancer Res
, vol.66
, pp. 29-33
-
-
Fiegl, H.1
Millinger, S.2
Goebel, G.3
Muller-Holzner, E.4
Marth, C.5
Laird, P.W.6
-
42
-
-
79959376030
-
Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation
-
J. Fuxe, S. Tabruyn, K. Colton, H. Zaid, A. Adams, and P. Baluk Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation Am J Pathol 178 2011 2897 2909
-
(2011)
Am J Pathol
, vol.178
, pp. 2897-2909
-
-
Fuxe, J.1
Tabruyn, S.2
Colton, K.3
Zaid, H.4
Adams, A.5
Baluk, P.6
-
43
-
-
36749013537
-
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
-
C. Gaggioli, S. Hooper, C. Hidalgo-Carcedo, R. Grosse, J.F. Marshall, and K. Harrington Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells Nat Cell Biol 9 2007 1392 1400
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1392-1400
-
-
Gaggioli, C.1
Hooper, S.2
Hidalgo-Carcedo, C.3
Grosse, R.4
Marshall, J.F.5
Harrington, K.6
-
44
-
-
84861190138
-
A preclinical and clinical review of aflibercept for the management of cancer
-
A. Gaya, and V. Tse A preclinical and clinical review of aflibercept for the management of cancer Cancer Treat Rev 38 2012 484 493
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 484-493
-
-
Gaya, A.1
Tse, V.2
-
45
-
-
72949096367
-
Chemokines in tumor-associated angiogenesis
-
P.A. Gerber, A. Hippe, B.A. Buhren, A. Muller, and B. Homey Chemokines in tumor-associated angiogenesis Biol Chem 390 2009 1213 1223
-
(2009)
Biol Chem
, vol.390
, pp. 1213-1223
-
-
Gerber, P.A.1
Hippe, A.2
Buhren, B.A.3
Muller, A.4
Homey, B.5
-
46
-
-
52049127235
-
A phase 2, randomized, double-blind, placebo-controlled trial of clinical activity and safety of subcutaneous A6 in women with asymptomatic CA125 progression after first-line chemotherapy of epithelial ovarian cancer
-
S.A. Ghamande, M.H. Silverman, W. Huh, K. Behbakht, G. Ball, and L. Cuasay A phase 2, randomized, double-blind, placebo-controlled trial of clinical activity and safety of subcutaneous A6 in women with asymptomatic CA125 progression after first-line chemotherapy of epithelial ovarian cancer Gynecol Oncol 111 2008 89 94
-
(2008)
Gynecol Oncol
, vol.111
, pp. 89-94
-
-
Ghamande, S.A.1
Silverman, M.H.2
Huh, W.3
Behbakht, K.4
Ball, G.5
Cuasay, L.6
-
47
-
-
0036317838
-
Transforming growth factor-β1 triggers hepatocellular carcinoma invasiveness via alpha3beta1 integrin
-
G. Giannelli, E. Fransvea, F. Marinosci, C. Bergamini, S. Colucci, and O. Schiraldi Transforming growth factor-β1 triggers hepatocellular carcinoma invasiveness via alpha3beta1 integrin Am J Pathol 161 2002 183 193
-
(2002)
Am J Pathol
, vol.161
, pp. 183-193
-
-
Giannelli, G.1
Fransvea, E.2
Marinosci, F.3
Bergamini, C.4
Colucci, S.5
Schiraldi, O.6
-
48
-
-
84855593960
-
Malignant spiculated breast masses: Dynamic contrast enhanced MR (DCE-MR) imaging enhancement characteristics and histopathological correlation
-
G. Gokalp, U. Topal, N. Yildirim, and S. Tolunay Malignant spiculated breast masses: dynamic contrast enhanced MR (DCE-MR) imaging enhancement characteristics and histopathological correlation Eur J Radiol 81 2012 203 208
-
(2012)
Eur J Radiol
, vol.81
, pp. 203-208
-
-
Gokalp, G.1
Topal, U.2
Yildirim, N.3
Tolunay, S.4
-
49
-
-
84869499839
-
Phase 1 dose-escalation trial evaluating the combination of the selective MET (mesenchymal-epithelial transition factor) inhibitor tivantinib (ARQ 197) plus erlotinib
-
10.1002/cncr.27575
-
J.W. Goldman, I. Laux, F. Chai, R.E. Savage, D. Ferrari, and E.G. Garmey Phase 1 dose-escalation trial evaluating the combination of the selective MET (mesenchymal-epithelial transition factor) inhibitor tivantinib (ARQ 197) plus erlotinib Cancer 2012 10.1002/cncr.27575
-
(2012)
Cancer
-
-
Goldman, J.W.1
Laux, I.2
Chai, F.3
Savage, R.E.4
Ferrari, D.5
Garmey, E.G.6
-
50
-
-
56249141809
-
Experience in phase i trials and an upcoming phase Ii study with uPA inhibitors in metastatic breast cancer
-
L.J. Goldstein Experience in phase I trials and an upcoming phase Ii study with uPA inhibitors in metastatic breast cancer Breast Care (Basel) 3 2008 25 28
-
(2008)
Breast Care (Basel)
, vol.3
, pp. 25-28
-
-
Goldstein, L.J.1
-
51
-
-
75849116069
-
Molecular biology of cancer-associated fibroblasts: Can these cells be targeted in anti-cancer therapy?
-
T.A. Gonda, A. Varro, T.C. Wang, and B. Tycko Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy? Semin Cell Dev Biol 21 2010 2 10
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 2-10
-
-
Gonda, T.A.1
Varro, A.2
Wang, T.C.3
Tycko, B.4
-
52
-
-
81155151807
-
Randomized, placebo-controlled phase III study of docetaxel plus carboplatin with celecoxib and cyclooxygenase-2 expression as a biomarker for patients with advanced non-small-cell lung cancer: The NVALT-4 study
-
H.J. Groen, H. Sietsma, A. Vincent, M.M. Hochstenbag, J.W. van Putten, and A. van den Berg Randomized, placebo-controlled phase III study of docetaxel plus carboplatin with celecoxib and cyclooxygenase-2 expression as a biomarker for patients with advanced non-small-cell lung cancer: the NVALT-4 study J Clin Oncol 29 2011 4320 4326
-
(2011)
J Clin Oncol
, vol.29
, pp. 4320-4326
-
-
Groen, H.J.1
Sietsma, H.2
Vincent, A.3
Hochstenbag, M.M.4
Van Putten, J.W.5
Van Den Berg, A.6
-
53
-
-
0035315836
-
Synthesis and degradation of basement membranes and extracellular matrix and their regulation by TGF-β in invasive carcinomas
-
H.G. Hagedorn, B.E. Bachmeier, and A.G. Nerlich Synthesis and degradation of basement membranes and extracellular matrix and their regulation by TGF-β in invasive carcinomas Int J Oncol 18 2001 669 681
-
(2001)
Int J Oncol
, vol.18
, pp. 669-681
-
-
Hagedorn, H.G.1
Bachmeier, B.E.2
Nerlich, A.G.3
-
54
-
-
34548604258
-
Adult human fibroblasts are potent immunoregulatory cells and functionally equivalent to mesenchymal stem cells
-
M.A. Haniffa, X.N. Wang, U. Holtick, M. Rae, J.D. Isaacs, and A.M. Dickinson Adult human fibroblasts are potent immunoregulatory cells and functionally equivalent to mesenchymal stem cells J Immunol 179 2007 1595 1604
-
(2007)
J Immunol
, vol.179
, pp. 1595-1604
-
-
Haniffa, M.A.1
Wang, X.N.2
Holtick, U.3
Rae, M.4
Isaacs, J.D.5
Dickinson, A.M.6
-
55
-
-
33144465069
-
Gene promoter methylation in prostate tumor-associated stromal cells
-
J.A. Hanson, J.W. Gillespie, A. Grover, M.A. Tangrea, R.F. Chuaqui, and M.R. Emmert-Buck Gene promoter methylation in prostate tumor-associated stromal cells J Natl Cancer Inst 98 2006 255 261
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 255-261
-
-
Hanson, J.A.1
Gillespie, J.W.2
Grover, A.3
Tangrea, M.A.4
Chuaqui, R.F.5
Emmert-Buck, M.R.6
-
56
-
-
54249115529
-
A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells
-
T.N. Hartmann, V. Grabovsky, R. Pasvolsky, Z. Shulman, E.C. Buss, and A. Spiegel A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells J Leukoc Biol 84 2008 1130 1140
-
(2008)
J Leukoc Biol
, vol.84
, pp. 1130-1140
-
-
Hartmann, T.N.1
Grabovsky, V.2
Pasvolsky, R.3
Shulman, Z.4
Buss, E.C.5
Spiegel, A.6
-
58
-
-
0032904231
-
Tenascin-C inhibits beta1 integrin-dependent T lymphocyte adhesion to fibronectin through the binding of its fnIII 1-5 repeats to fibronectin
-
D. Hauzenberger, P. Olivier, D. Gundersen, and C. Ruegg Tenascin-C inhibits beta1 integrin-dependent T lymphocyte adhesion to fibronectin through the binding of its fnIII 1-5 repeats to fibronectin Eur J Immunol 29 1999 1435 1447
-
(1999)
Eur J Immunol
, vol.29
, pp. 1435-1447
-
-
Hauzenberger, D.1
Olivier, P.2
Gundersen, D.3
Ruegg, C.4
-
59
-
-
34250189539
-
Clinical implications of fibroblast activation protein in patients with colon cancer
-
L.R. Henry, H.O. Lee, J.S. Lee, A. Klein-Szanto, P. Watts, and E.A. Ross Clinical implications of fibroblast activation protein in patients with colon cancer Clin Cancer Res 13 2007 1736 1741
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1736-1741
-
-
Henry, L.R.1
Lee, H.O.2
Lee, J.S.3
Klein-Szanto, A.4
Watts, P.5
Ross, E.A.6
-
60
-
-
0029946569
-
Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response
-
K.J. Heppner, L.M. Matrisian, R.A. Jensen, and W.H. Rodgers Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response Am J Pathol 149 1996 273 282
-
(1996)
Am J Pathol
, vol.149
, pp. 273-282
-
-
Heppner, K.J.1
Matrisian, L.M.2
Jensen, R.A.3
Rodgers, W.H.4
-
61
-
-
77949394260
-
A randomized phase 2 study of etaracizumab, a monoclonal antibody against integrin alpha(v)beta(3), + or - Dacarbazine in patients with stage IV metastatic melanoma
-
P. Hersey, J. Sosman, S. O'Day, J. Richards, A. Bedikian, and R. Gonzalez A randomized phase 2 study of etaracizumab, a monoclonal antibody against integrin alpha(v)beta(3), + or - dacarbazine in patients with stage IV metastatic melanoma Cancer 116 2010 1526 1534
-
(2010)
Cancer
, vol.116
, pp. 1526-1534
-
-
Hersey, P.1
Sosman, J.2
O'Day, S.3
Richards, J.4
Bedikian, A.5
Gonzalez, R.6
-
62
-
-
33745963397
-
A phase III randomized trial of BAY 12-9566 (tanomastat) as maintenance therapy in patients with advanced ovarian cancer responsive to primary surgery and paclitaxel/platinum containing chemotherapy: A National Cancer Institute of Canada Clinical Trials Group Study
-
H. Hirte, I.B. Vergote, J.R. Jeffrey, R.N. Grimshaw, S. Coppieters, and B. Schwartz A phase III randomized trial of BAY 12-9566 (tanomastat) as maintenance therapy in patients with advanced ovarian cancer responsive to primary surgery and paclitaxel/platinum containing chemotherapy: a National Cancer Institute of Canada Clinical Trials Group Study Gynecol Oncol 102 2006 300 308
-
(2006)
Gynecol Oncol
, vol.102
, pp. 300-308
-
-
Hirte, H.1
Vergote, I.B.2
Jeffrey, J.R.3
Grimshaw, R.N.4
Coppieters, S.5
Schwartz, B.6
-
64
-
-
0037219532
-
Stromal antigen targeting by a humanised monoclonal antibody: An early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer
-
R.D. Hofheinz, S.E. al-Batran, F. Hartmann, G. Hartung, D. Jager, and C. Renner Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer Onkologie 26 2003 44 48
-
(2003)
Onkologie
, vol.26
, pp. 44-48
-
-
Hofheinz, R.D.1
Al-Batran, S.E.2
Hartmann, F.3
Hartung, G.4
Jager, D.5
Renner, C.6
-
65
-
-
62549099627
-
Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast
-
M. Hu, G. Peluffo, H. Chen, R. Gelman, S. Schnitt, and K. Polyak Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast Proc Natl Acad Sci U S A 106 2009 3372 3377
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3372-3377
-
-
Hu, M.1
Peluffo, G.2
Chen, H.3
Gelman, R.4
Schnitt, S.5
Polyak, K.6
-
66
-
-
23044499067
-
Distinct epigenetic changes in the stromal cells of breast cancers
-
M. Hu, J. Yao, L. Cai, K.E. Bachman, F. van den Brule, and V. Velculescu Distinct epigenetic changes in the stromal cells of breast cancers Nat Genet 37 2005 899 905
-
(2005)
Nat Genet
, vol.37
, pp. 899-905
-
-
Hu, M.1
Yao, J.2
Cai, L.3
Bachman, K.E.4
Van Den Brule, F.5
Velculescu, V.6
-
67
-
-
80455158257
-
Expression and role of fibroblast activation protein-alpha in microinvasive breast carcinoma
-
X. Hua, L. Yu, X. Huang, Z. Liao, and Q. Xian Expression and role of fibroblast activation protein-alpha in microinvasive breast carcinoma Diagn Pathol 6 2011 111
-
(2011)
Diagn Pathol
, vol.6
, pp. 111
-
-
Hua, X.1
Yu, L.2
Huang, X.3
Liao, Z.4
Xian, Q.5
-
68
-
-
79960478878
-
Evaluation of the tumor targeting of a FAPalpha-based doxorubicin prodrug
-
S. Huang, R. Fang, J. Xu, S. Qiu, H. Zhang, and J. Du Evaluation of the tumor targeting of a FAPalpha-based doxorubicin prodrug J Drug Target 19 2011 487 496
-
(2011)
J Drug Target
, vol.19
, pp. 487-496
-
-
Huang, S.1
Fang, R.2
Xu, J.3
Qiu, S.4
Zhang, H.5
Du, J.6
-
69
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
H. Hurwitz, L. Fehrenbacher, W. Novotny, T. Cartwright, J. Hainsworth, and W. Heim Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer N Engl J Med 350 2004 2335 2342
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
-
70
-
-
80053405625
-
Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma
-
H. Ijichi, A. Chytil, A.E. Gorska, M.E. Aakre, B. Bierie, and M. Tada Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma J Clin Invest 121 2011 4106 4117
-
(2011)
J Clin Invest
, vol.121
, pp. 4106-4117
-
-
Ijichi, H.1
Chytil, A.2
Gorska, A.E.3
Aakre, M.E.4
Bierie, B.5
Tada, M.6
-
71
-
-
20044376846
-
IL-8 promotes cell proliferation and migration through metalloproteinase-cleavage proHB-EGF in human colon carcinoma cells
-
Y. Itoh, T. Joh, S. Tanida, M. Sasaki, H. Kataoka, and K. Itoh IL-8 promotes cell proliferation and migration through metalloproteinase-cleavage proHB-EGF in human colon carcinoma cells Cytokine 29 2005 275 282
-
(2005)
Cytokine
, vol.29
, pp. 275-282
-
-
Itoh, Y.1
Joh, T.2
Tanida, S.3
Sasaki, M.4
Kataoka, H.5
Itoh, K.6
-
72
-
-
33646026720
-
Correlation between MRI and histopathologic findings in stage i cervical carcinomas: Influence of stromal desmoplastic reaction
-
K. Itoh, T. Shiozawa, S. Ohira, S. Shiohara, and I. Konishi Correlation between MRI and histopathologic findings in stage I cervical carcinomas: influence of stromal desmoplastic reaction Int J Gynecol Cancer 16 2006 610 614
-
(2006)
Int J Gynecol Cancer
, vol.16
, pp. 610-614
-
-
Itoh, K.1
Shiozawa, T.2
Ohira, S.3
Shiohara, S.4
Konishi, I.5
-
73
-
-
80355139007
-
The antisense oligonucleotide trabedersen (AP 12009) for the targeted inhibition of TGF-β2
-
F. Jaschinski, T. Rothhammer, P. Jachimczak, C. Seitz, A. Schneider, and K.H. Schlingensiepen The antisense oligonucleotide trabedersen (AP 12009) for the targeted inhibition of TGF-β2 Curr Pharm Biotechnol 12 2011 2203 2213
-
(2011)
Curr Pharm Biotechnol
, vol.12
, pp. 2203-2213
-
-
Jaschinski, F.1
Rothhammer, T.2
Jachimczak, P.3
Seitz, C.4
Schneider, A.5
Schlingensiepen, K.H.6
-
74
-
-
33745192635
-
Autocrine PDGFR signaling promotes mammary cancer metastasis
-
M. Jechlinger, A. Sommer, R. Moriggl, P. Seither, N. Kraut, and P. Capodiecci Autocrine PDGFR signaling promotes mammary cancer metastasis J Clin Invest 116 2006 1561 1570
-
(2006)
J Clin Invest
, vol.116
, pp. 1561-1570
-
-
Jechlinger, M.1
Sommer, A.2
Moriggl, R.3
Seither, P.4
Kraut, N.5
Capodiecci, P.6
-
75
-
-
80053626854
-
Prognostic significance of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor (PAI-1) in patients with primary invasive ductal breast carcinoma - A 7.5-year follow-up study
-
S. Jelisavac-Cosic, M. Sirotkovic-Skerlev, A. Kulic, J. Jakic-Razumovic, Z. Kovac, and D. Vrbanec Prognostic significance of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor (PAI-1) in patients with primary invasive ductal breast carcinoma - a 7.5-year follow-up study Tumori 97 2011 532 539
-
(2011)
Tumori
, vol.97
, pp. 532-539
-
-
Jelisavac-Cosic, S.1
Sirotkovic-Skerlev, M.2
Kulic, A.3
Jakic-Razumovic, J.4
Kovac, Z.5
Vrbanec, D.6
-
76
-
-
57149111920
-
Global hypomethylation of genomic DNA in cancer-associated myofibroblasts
-
L. Jiang, T.A. Gonda, M.V. Gamble, M. Salas, V. Seshan, and S. Tu Global hypomethylation of genomic DNA in cancer-associated myofibroblasts Cancer Res 68 2008 9900 9908
-
(2008)
Cancer Res
, vol.68
, pp. 9900-9908
-
-
Jiang, L.1
Gonda, T.A.2
Gamble, M.V.3
Salas, M.4
Seshan, V.5
Tu, S.6
-
77
-
-
77953725777
-
Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: A pivotal role of CCL7
-
D.W. Jung, Z.M. Che, J. Kim, K. Kim, K.Y. Kim, and D. Williams Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7 Int J Cancer 127 2010 332 344
-
(2010)
Int J Cancer
, vol.127
, pp. 332-344
-
-
Jung, D.W.1
Che, Z.M.2
Kim, J.3
Kim, K.4
Kim, K.Y.5
Williams, D.6
-
78
-
-
0035947766
-
Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration
-
M. Kajita, Y. Itoh, T. Chiba, H. Mori, A. Okada, and H. Kinoh Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration J Cell Biol 153 2001 893 904
-
(2001)
J Cell Biol
, vol.153
, pp. 893-904
-
-
Kajita, M.1
Itoh, Y.2
Chiba, T.3
Mori, H.4
Okada, A.5
Kinoh, H.6
-
80
-
-
58149179443
-
UPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo
-
O. Kargiotis, C. Chetty, V. Gogineni, C.S. Gondi, S.M. Pulukuri, and A.P. Kyritsis uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo Int J Oncol 33 2008 937 947
-
(2008)
Int J Oncol
, vol.33
, pp. 937-947
-
-
Kargiotis, O.1
Chetty, C.2
Gogineni, V.3
Gondi, C.S.4
Pulukuri, S.M.5
Kyritsis, A.P.6
-
81
-
-
77749304055
-
COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems
-
H. Katoh, K. Hosono, Y. Ito, T. Suzuki, Y. Ogawa, and H. Kubo COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems Am J Pathol 176 2010 1469 1483
-
(2010)
Am J Pathol
, vol.176
, pp. 1469-1483
-
-
Katoh, H.1
Hosono, K.2
Ito, Y.3
Suzuki, T.4
Ogawa, Y.5
Kubo, H.6
-
82
-
-
20444421293
-
Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): Cell-surface proteases that activate cell signaling and are potential targets for cancer therapy
-
T. Kelly Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): cell-surface proteases that activate cell signaling and are potential targets for cancer therapy Drug Resist Updat 8 2005 51 58
-
(2005)
Drug Resist Updat
, vol.8
, pp. 51-58
-
-
Kelly, T.1
-
84
-
-
42449111736
-
Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases
-
S.Y. Kim, C.H. Lee, B.V. Midura, C. Yeung, A. Mendoza, and S.H. Hong Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases Clin Exp Metastasis 25 2008 201 211
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 201-211
-
-
Kim, S.Y.1
Lee, C.H.2
Midura, B.V.3
Yeung, C.4
Mendoza, A.5
Hong, S.H.6
-
85
-
-
0034900427
-
A multi-institutional phase ii study of SU101, a platelet-derived growth factor receptor inhibitor, for patients with hormone-refractory prostate cancer
-
Y.J. Ko, E.J. Small, F. Kabbinavar, A. Chachoua, S. Taneja, and D. Reese A multi-institutional phase ii study of SU101, a platelet-derived growth factor receptor inhibitor, for patients with hormone-refractory prostate cancer Clin Cancer Res 7 2001 800 805
-
(2001)
Clin Cancer Res
, vol.7
, pp. 800-805
-
-
Ko, Y.J.1
Small, E.J.2
Kabbinavar, F.3
Chachoua, A.4
Taneja, S.5
Reese, D.6
-
86
-
-
34547697832
-
Low dose geldanamycin inhibits hepatocyte growth factor and hypoxia-stimulated invasion of cancer cells
-
F. Koga, S. Tsutsumi, and L.M. Neckers Low dose geldanamycin inhibits hepatocyte growth factor and hypoxia-stimulated invasion of cancer cells Cell Cycle 6 2007 1393 1402
-
(2007)
Cell Cycle
, vol.6
, pp. 1393-1402
-
-
Koga, F.1
Tsutsumi, S.2
Neckers, L.M.3
-
87
-
-
78650563018
-
Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
-
Y. Kojima, A. Acar, E.N. Eaton, K.T. Mellody, C. Scheel, and I. Ben-Porath Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts Proc Natl Acad Sci U S A 107 2010 20009 20014
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 20009-20014
-
-
Kojima, Y.1
Acar, A.2
Eaton, E.N.3
Mellody, K.T.4
Scheel, C.5
Ben-Porath, I.6
-
88
-
-
38549148896
-
Biochemical and biophysical aspects of collagen nanostructure in the extracellular matrix
-
L. Kolacna, J. Bakesova, F. Varga, E. Kostakova, L. Planka, and A. Necas Biochemical and biophysical aspects of collagen nanostructure in the extracellular matrix Physiol Res 56 Suppl. 1 2007 S51 S60
-
(2007)
Physiol Res
, vol.56
, Issue.SUPPL. 1
-
-
Kolacna, L.1
Bakesova, J.2
Varga, F.3
Kostakova, E.4
Planka, L.5
Necas, A.6
-
89
-
-
84856462493
-
Adding to the mix: Fibroblast growth factor and platelet-derived growth factor receptor pathways as targets in non-small cell lung cancer
-
S.A. Kono, L.E. Heasley, R.C. Doebele, and D.R. Camidge Adding to the mix: fibroblast growth factor and platelet-derived growth factor receptor pathways as targets in non-small cell lung cancer Curr Cancer Drug Targets 12 2012 107 123
-
(2012)
Curr Cancer Drug Targets
, vol.12
, pp. 107-123
-
-
Kono, S.A.1
Heasley, L.E.2
Doebele, R.C.3
Camidge, D.R.4
-
90
-
-
33746253891
-
Interaction between stromal fibroblasts and colorectal cancer cells in the expression of vascular endothelial growth factor
-
Y. Koshida, M. Kuranami, and M. Watanabe Interaction between stromal fibroblasts and colorectal cancer cells in the expression of vascular endothelial growth factor J Surg Res 134 2006 270 277
-
(2006)
J Surg Res
, vol.134
, pp. 270-277
-
-
Koshida, Y.1
Kuranami, M.2
Watanabe, M.3
-
91
-
-
78149298209
-
Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha
-
M. Kraman, P.J. Bambrough, J.N. Arnold, E.W. Roberts, L. Magiera, and J.O. Jones Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha Science 330 2010 827 830
-
(2010)
Science
, vol.330
, pp. 827-830
-
-
Kraman, M.1
Bambrough, P.J.2
Arnold, J.N.3
Roberts, E.W.4
Magiera, L.5
Jones, J.O.6
-
92
-
-
70349443680
-
Ethnic differences and functional analysis of MET mutations in lung cancer
-
S. Krishnaswamy, R. Kanteti, J.S. Duke-Cohan, S. Loganathan, W. Liu, and P.C. Ma Ethnic differences and functional analysis of MET mutations in lung cancer Clin Cancer Res 15 2009 5714 5723
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5714-5723
-
-
Krishnaswamy, S.1
Kanteti, R.2
Duke-Cohan, J.S.3
Loganathan, S.4
Liu, W.5
Ma, P.C.6
-
93
-
-
67650674112
-
Ramucirumab, a fully human mAb to the transmembrane signaling tyrosine kinase VEGFR-2 for the potential treatment of cancer
-
Y. Krupitskaya, and H.A. Wakelee Ramucirumab, a fully human mAb to the transmembrane signaling tyrosine kinase VEGFR-2 for the potential treatment of cancer Curr Opin Investig Drugs 10 2009 597 605
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 597-605
-
-
Krupitskaya, Y.1
Wakelee, H.A.2
-
94
-
-
0036843937
-
Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas
-
K. Kurose, K. Gilley, S. Matsumoto, P.H. Watson, X.P. Zhou, and C. Eng Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas Nat Genet 32 2002 355 357
-
(2002)
Nat Genet
, vol.32
, pp. 355-357
-
-
Kurose, K.1
Gilley, K.2
Matsumoto, S.3
Watson, P.H.4
Zhou, X.P.5
Eng, C.6
-
95
-
-
47049117155
-
P53 mutations in stromal fibroblasts sensitize tumors against chemotherapy
-
D. Lafkas, G. Trimis, A.G. Papavassiliou, and H. Kiaris P53 mutations in stromal fibroblasts sensitize tumors against chemotherapy Int J Cancer 123 2008 967 971
-
(2008)
Int J Cancer
, vol.123
, pp. 967-971
-
-
Lafkas, D.1
Trimis, G.2
Papavassiliou, A.G.3
Kiaris, H.4
-
96
-
-
66849125864
-
Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin
-
A.M. LeBeau, W.N. Brennen, S. Aggarwal, and S.R. Denmeade Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin Mol Cancer Ther 8 2009 1378 1386
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1378-1386
-
-
Lebeau, A.M.1
Brennen, W.N.2
Aggarwal, S.3
Denmeade, S.R.4
-
97
-
-
79958250916
-
FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells
-
H.O. Lee, S.R. Mullins, J. Franco-Barraza, M. Valianou, E. Cukierman, and J.D. Cheng FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells BMC Cancer 11 2011 245
-
(2011)
BMC Cancer
, vol.11
, pp. 245
-
-
Lee, H.O.1
Mullins, S.R.2
Franco-Barraza, J.3
Valianou, M.4
Cukierman, E.5
Cheng, J.D.6
-
98
-
-
79957639294
-
Phase II study of the combination carboplatin plus celecoxib in heavily pre-treated recurrent ovarian cancer patients
-
F. Legge, A. Paglia, M. D'Asta, G. Fuoco, G. Scambia, and G. Ferrandina Phase II study of the combination carboplatin plus celecoxib in heavily pre-treated recurrent ovarian cancer patients BMC Cancer 11 2011 214
-
(2011)
BMC Cancer
, vol.11
, pp. 214
-
-
Legge, F.1
Paglia, A.2
D'Asta, M.3
Fuoco, G.4
Scambia, G.5
Ferrandina, G.6
-
99
-
-
85047694353
-
Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors
-
X. Li, M. Tjwa, L. Moons, P. Fons, A. Noel, and A. Ny Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors J Clin Invest 115 2005 118 127
-
(2005)
J Clin Invest
, vol.115
, pp. 118-127
-
-
Li, X.1
Tjwa, M.2
Moons, L.3
Fons, P.4
Noel, A.5
Ny, A.6
-
100
-
-
10944242667
-
Antiangiogenic therapy: Creating a unique "window" of opportunity
-
M.I. Lin, and W.C. Sessa Antiangiogenic therapy: creating a unique "window" of opportunity Cancer Cell 6 2004 529 531
-
(2004)
Cancer Cell
, vol.6
, pp. 529-531
-
-
Lin, M.I.1
Sessa, W.C.2
-
101
-
-
84863116741
-
Fibroblast activation protein: A potential therapeutic target in cancer
-
R. Liu, H. Li, L. Liu, J. Yu, and X. Ren Fibroblast activation protein: a potential therapeutic target in cancer Cancer Biol Ther 13 2012 123 129
-
(2012)
Cancer Biol Ther
, vol.13
, pp. 123-129
-
-
Liu, R.1
Li, H.2
Liu, L.3
Yu, J.4
Ren, X.5
-
102
-
-
0035877113
-
Blockade of alpha 5 beta 1 integrins reverses the inhibitory effect of tenascin on chemotaxis of human monocytes and polymorphonuclear leukocytes through three-dimensional gels of extracellular matrix proteins
-
J.D. Loike, L. Cao, S. Budhu, S. Hoffman, and S.C. Silverstein Blockade of alpha 5 beta 1 integrins reverses the inhibitory effect of tenascin on chemotaxis of human monocytes and polymorphonuclear leukocytes through three-dimensional gels of extracellular matrix proteins J Immunol 166 2001 7534 7542
-
(2001)
J Immunol
, vol.166
, pp. 7534-7542
-
-
Loike, J.D.1
Cao, L.2
Budhu, S.3
Hoffman, S.4
Silverstein, S.C.5
-
103
-
-
56749107194
-
The tumor microenvironment and its contribution to tumor evolution toward metastasis
-
G. Lorusso, and C. Ruegg The tumor microenvironment and its contribution to tumor evolution toward metastasis Histochem Cell Biol 130 2008 1091 1103
-
(2008)
Histochem Cell Biol
, vol.130
, pp. 1091-1103
-
-
Lorusso, G.1
Ruegg, C.2
-
104
-
-
78751571123
-
Culture of human breast cancer cell line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity
-
G. Maity, P.R. Choudhury, T. Sen, K.K. Ganguly, H. Sil, and A. Chatterjee Culture of human breast cancer cell line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity Tumour Biol 32 2011 129 138
-
(2011)
Tumour Biol
, vol.32
, pp. 129-138
-
-
Maity, G.1
Choudhury, P.R.2
Sen, T.3
Ganguly, K.K.4
Sil, H.5
Chatterjee, A.6
-
105
-
-
71749087055
-
The role of stromal-derived factor-1-CXCR7 axis in development and cancer
-
R.B. Maksym, M. Tarnowski, K. Grymula, J. Tarnowska, M. Wysoczynski, and R. Liu The role of stromal-derived factor-1-CXCR7 axis in development and cancer Eur J Pharmacol 625 2009 31 40
-
(2009)
Eur J Pharmacol
, vol.625
, pp. 31-40
-
-
Maksym, R.B.1
Tarnowski, M.2
Grymula, K.3
Tarnowska, J.4
Wysoczynski, M.5
Liu, R.6
-
106
-
-
36849094431
-
Matrix metalloproteinases as modulators of inflammation
-
A.M. Manicone, and J.K. McGuire Matrix metalloproteinases as modulators of inflammation Semin Cell Dev Biol 19 2008 34 41
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 34-41
-
-
Manicone, A.M.1
McGuire, J.K.2
-
107
-
-
33846200332
-
Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: Implications for wound healing and fibrogenesis
-
J. Mann, F. Oakley, F. Akiboye, A. Elsharkawy, A.W. Thorne, and D.A. Mann Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis Cell Death Differ 14 2007 275 285
-
(2007)
Cell Death Differ
, vol.14
, pp. 275-285
-
-
Mann, J.1
Oakley, F.2
Akiboye, F.3
Elsharkawy, A.4
Thorne, A.W.5
Mann, D.A.6
-
108
-
-
47549090432
-
TGFβ in Cancer
-
J. Massague TGFβ in Cancer Cell 134 2008 215 230
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massague, J.1
-
109
-
-
33745465488
-
Hepatocyte growth factor and the Met system as a mediator of tumor-stromal interactions
-
K. Matsumoto, and T. Nakamura Hepatocyte growth factor and the Met system as a mediator of tumor-stromal interactions Int J Cancer 119 2006 477 483
-
(2006)
Int J Cancer
, vol.119
, pp. 477-483
-
-
Matsumoto, K.1
Nakamura, T.2
-
110
-
-
0036188465
-
Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer
-
G. Maulik, T. Kijima, P.C. Ma, S.K. Ghosh, J. Lin, and G.I. Shapiro Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer Clin Cancer Res 8 2002 620 627
-
(2002)
Clin Cancer Res
, vol.8
, pp. 620-627
-
-
Maulik, G.1
Kijima, T.2
Ma, P.C.3
Ghosh, S.K.4
Lin, J.5
Shapiro, G.I.6
-
111
-
-
75449092617
-
Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma
-
A. Mazzocca, E. Fransvea, F. Dituri, L. Lupo, S. Antonaci, and G. Giannelli Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma Hepatology 51 2010 523 534
-
(2010)
Hepatology
, vol.51
, pp. 523-534
-
-
Mazzocca, A.1
Fransvea, E.2
Dituri, F.3
Lupo, L.4
Antonaci, S.5
Giannelli, G.6
-
112
-
-
70350059078
-
Inhibition of transforming growth factor beta receptor i kinase blocks hepatocellular carcinoma growth through neo-angiogenesis regulation
-
A. Mazzocca, E. Fransvea, G. Lavezzari, S. Antonaci, and G. Giannelli Inhibition of transforming growth factor beta receptor I kinase blocks hepatocellular carcinoma growth through neo-angiogenesis regulation Hepatology 50 2009 1140 1151
-
(2009)
Hepatology
, vol.50
, pp. 1140-1151
-
-
Mazzocca, A.1
Fransvea, E.2
Lavezzari, G.3
Antonaci, S.4
Giannelli, G.5
-
113
-
-
77649090075
-
Cyclooxygenase-2 and cancer treatment: Understanding the risk should be worth the reward
-
D.G. Menter, R.L. Schilsky, and R.N. DuBois Cyclooxygenase-2 and cancer treatment: understanding the risk should be worth the reward Clin Cancer Res 16 2010 1384 1390
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1384-1390
-
-
Menter, D.G.1
Schilsky, R.L.2
Dubois, R.N.3
-
114
-
-
56249086829
-
The oral serine protease inhibitor WX-671 - First experience in patients with advanced head and neck carcinoma
-
J.E. Meyer, C. Brocks, H. Graefe, C. Mala, N. Thans, and M. Burgle The oral serine protease inhibitor WX-671 - first experience in patients with advanced head and neck carcinoma Breast Care (Basel) 3 2008 20 24
-
(2008)
Breast Care (Basel)
, vol.3
, pp. 20-24
-
-
Meyer, J.E.1
Brocks, C.2
Graefe, H.3
Mala, C.4
Thans, N.5
Burgle, M.6
-
115
-
-
36349034540
-
Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment
-
L. Mueller, F.A. Goumas, M. Affeldt, S. Sandtner, U.M. Gehling, and S. Brilloff Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment Am J Pathol 171 2007 1608 1618
-
(2007)
Am J Pathol
, vol.171
, pp. 1608-1618
-
-
Mueller, L.1
Goumas, F.A.2
Affeldt, M.3
Sandtner, S.4
Gehling, U.M.5
Brilloff, S.6
-
116
-
-
77954213935
-
TNF-alpha similarly induces IL-6 and MCP-1 in fibroblasts from colorectal liver metastases and normal liver fibroblasts
-
L. Mueller, L.V. Seggern, J. Schumacher, F. Goumas, C. Wilms, and F. Braun TNF-alpha similarly induces IL-6 and MCP-1 in fibroblasts from colorectal liver metastases and normal liver fibroblasts Biochem Biophys Res Commun 397 2010 586 591
-
(2010)
Biochem Biophys Res Commun
, vol.397
, pp. 586-591
-
-
Mueller, L.1
Seggern, L.V.2
Schumacher, J.3
Goumas, F.4
Wilms, C.5
Braun, F.6
-
117
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
A. Muller, B. Homey, H. Soto, N. Ge, D. Catron, and M.E. Buchanan Involvement of chemokine receptors in breast cancer metastasis Nature 410 2001 50 56
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
-
118
-
-
84868193304
-
A safety run-in and randomized phase 2 study of cilengitide combined with chemoradiation for newly diagnosed glioblastoma (NABTT 0306)
-
10.1002/cncr.27585
-
L.B. Nabors, T. Mikkelsen, M.E. Hegi, X. Ye, T. Batchelor, and G. Lesser A safety run-in and randomized phase 2 study of cilengitide combined with chemoradiation for newly diagnosed glioblastoma (NABTT 0306) Cancer 2012 10.1002/cncr.27585
-
(2012)
Cancer
-
-
Nabors, L.B.1
Mikkelsen, T.2
Hegi, M.E.3
Ye, X.4
Batchelor, T.5
Lesser, G.6
-
119
-
-
45549085803
-
An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments
-
J.S. Nam, M. Terabe, M. Mamura, M.J. Kang, H. Chae, and C. Stuelten An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments Cancer Res 68 2008 3835 3843
-
(2008)
Cancer Res
, vol.68
, pp. 3835-3843
-
-
Nam, J.S.1
Terabe, M.2
Mamura, M.3
Kang, M.J.4
Chae, H.5
Stuelten, C.6
-
120
-
-
41849147200
-
Phase II trial of single agent Val-boroPro (Talabostat) inhibiting fibroblast activation protein in patients with metastatic colorectal cancer
-
K. Narra, S.R. Mullins, H.O. Lee, B. Strzemkowski-Brun, K. Magalong, and V.J. Christiansen Phase II trial of single agent Val-boroPro (Talabostat) inhibiting fibroblast activation protein in patients with metastatic colorectal cancer Cancer Biol Ther 6 2007 1691 1699
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 1691-1699
-
-
Narra, K.1
Mullins, S.R.2
Lee, H.O.3
Strzemkowski-Brun, B.4
Magalong, K.5
Christiansen, V.J.6
-
121
-
-
72949083968
-
Co-overexpression of Met and hepatocyte growth factor promotes systemic metastasis in NCI-H460 non-small cell lung carcinoma cells
-
R. Navab, J. Liu, I. Seiden-Long, W. Shih, M. Li, and B. Bandarchi Co-overexpression of Met and hepatocyte growth factor promotes systemic metastasis in NCI-H460 non-small cell lung carcinoma cells Neoplasia 11 2009 1292 1300
-
(2009)
Neoplasia
, vol.11
, pp. 1292-1300
-
-
Navab, R.1
Liu, J.2
Seiden-Long, I.3
Shih, W.4
Li, M.5
Bandarchi, B.6
-
122
-
-
34247597310
-
Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells
-
M.R. Nazareth, L. Broderick, M.R. Simpson-Abelson, R.J. Kelleher Jr., S.J. Yokota, and R.B. Bankert Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells J Immunol 178 2007 5552 5562
-
(2007)
J Immunol
, vol.178
, pp. 5552-5562
-
-
Nazareth, M.R.1
Broderick, L.2
Simpson-Abelson, M.R.3
Kelleher, Jr.R.J.4
Yokota, S.J.5
Bankert, R.B.6
-
123
-
-
0038797885
-
Effects of hepatocyte growth factor on urokinase-type plasminogen activator (uPA) and uPA receptor in DU145 prostate cancer cells
-
K. Nishimura, K. Matsumiya, H. Miura, A. Tsujimura, N. Nonomura, and K. Matsumoto Effects of hepatocyte growth factor on urokinase-type plasminogen activator (uPA) and uPA receptor in DU145 prostate cancer cells Int J Androl 26 2003 175 179
-
(2003)
Int J Androl
, vol.26
, pp. 175-179
-
-
Nishimura, K.1
Matsumiya, K.2
Miura, H.3
Tsujimura, A.4
Nonomura, N.5
Matsumoto, K.6
-
124
-
-
80955178287
-
Type IV collagen as a tumour marker for colorectal liver metastases
-
H. Nystrom, P. Naredi, L. Hafstrom, and M. Sund Type IV collagen as a tumour marker for colorectal liver metastases Eur J Surg Oncol 37 2011 611 617
-
(2011)
Eur J Surg Oncol
, vol.37
, pp. 611-617
-
-
Nystrom, H.1
Naredi, P.2
Hafstrom, L.3
Sund, M.4
-
125
-
-
82355185942
-
Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways
-
O.O. Ogunwobi, and C. Liu Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways Clin Exp Metastasis 28 2011 721 731
-
(2011)
Clin Exp Metastasis
, vol.28
, pp. 721-731
-
-
Ogunwobi, O.O.1
Liu, C.2
-
126
-
-
0032829875
-
VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours
-
Y. Ohta, V. Shridhar, R.K. Bright, G.P. Kalemkerian, W. Du, and M. Carbone VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours Br J Cancer 81 1999 54 61
-
(1999)
Br J Cancer
, vol.81
, pp. 54-61
-
-
Ohta, Y.1
Shridhar, V.2
Bright, R.K.3
Kalemkerian, G.P.4
Du, W.5
Carbone, M.6
-
127
-
-
0033215242
-
Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
-
A.F. Olumi, G.D. Grossfeld, S.W. Hayward, P.R. Carroll, T.D. Tlsty, and G.R. Cunha Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium Cancer Res 59 1999 5002 5011
-
(1999)
Cancer Res
, vol.59
, pp. 5002-5011
-
-
Olumi, A.F.1
Grossfeld, G.D.2
Hayward, S.W.3
Carroll, P.R.4
Tlsty, T.D.5
Cunha, G.R.6
-
128
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
A. Orimo, P.B. Gupta, D.C. Sgroi, F. Arenzana-Seisdedos, T. Delaunay, and R. Naeem Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion Cell 121 2005 335 348
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
-
129
-
-
51649087512
-
Effective immunoconjugate therapy in cancer models targeting a serine protease of tumor fibroblasts
-
E. Ostermann, P. Garin-Chesa, K.H. Heider, M. Kalat, H. Lamche, and C. Puri Effective immunoconjugate therapy in cancer models targeting a serine protease of tumor fibroblasts Clin Cancer Res 14 2008 4584 4592
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4584-4592
-
-
Ostermann, E.1
Garin-Chesa, P.2
Heider, K.H.3
Kalat, M.4
Lamche, H.5
Puri, C.6
-
130
-
-
60949101225
-
Cancer-associated fibroblasts and tumor growth - Bystanders turning into key players
-
A. Ostman, and M. Augsten Cancer-associated fibroblasts and tumor growth - bystanders turning into key players Curr Opin Genet Dev 19 2009 67 73
-
(2009)
Curr Opin Genet Dev
, vol.19
, pp. 67-73
-
-
Ostman, A.1
Augsten, M.2
-
131
-
-
0024708518
-
The distribution of secondary growths in cancer of the breast
-
S. Paget The distribution of secondary growths in cancer of the breast Cancer Metastasis Rev 8 1989 98 101
-
(1989)
Cancer Metastasis Rev
, vol.8
, pp. 98-101
-
-
Paget, S.1
-
132
-
-
37349101054
-
Breast-cancer stromal cells with TP53 mutations and nodal metastases
-
A. Patocs, L. Zhang, Y. Xu, F. Weber, T. Caldes, and G.L. Mutter Breast-cancer stromal cells with TP53 mutations and nodal metastases N Engl J Med 357 2007 2543 2551
-
(2007)
N Engl J Med
, vol.357
, pp. 2543-2551
-
-
Patocs, A.1
Zhang, L.2
Xu, Y.3
Weber, F.4
Caldes, T.5
Mutter, G.L.6
-
133
-
-
67649975270
-
Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer
-
J. Paulsson, T. Sjoblom, P. Micke, F. Ponten, G. Landberg, and C.H. Heldin Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer Am J Pathol 175 2009 334 341
-
(2009)
Am J Pathol
, vol.175
, pp. 334-341
-
-
Paulsson, J.1
Sjoblom, T.2
Micke, P.3
Ponten, F.4
Landberg, G.5
Heldin, C.H.6
-
134
-
-
0037331707
-
Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma
-
O.W. Petersen, H.L. Nielsen, T. Gudjonsson, R. Villadsen, F. Rank, and E. Niebuhr Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma Am J Pathol 162 2003 391 402
-
(2003)
Am J Pathol
, vol.162
, pp. 391-402
-
-
Petersen, O.W.1
Nielsen, H.L.2
Gudjonsson, T.3
Villadsen, R.4
Rank, F.5
Niebuhr, E.6
-
135
-
-
80755127904
-
The microenvironment in breast cancer progression: Biology and implications for treatment
-
A.E. Place, S. Jin Huh, and K. Polyak The microenvironment in breast cancer progression: biology and implications for treatment Breast Cancer Res 13 2011 227
-
(2011)
Breast Cancer Res
, vol.13
, pp. 227
-
-
Place, A.E.1
Jin Huh, S.2
Polyak, K.3
-
136
-
-
0035706407
-
A pilot trial of Vitaxin, a humanized anti-vitronectin receptor (anti alpha v beta 3) antibody in patients with metastatic cancer
-
J.A. Posey, M.B. Khazaeli, A. DelGrosso, M.N. Saleh, C.Y. Lin, and W. Huse A pilot trial of Vitaxin, a humanized anti-vitronectin receptor (anti alpha v beta 3) antibody in patients with metastatic cancer Cancer Biother Radiopharm 16 2001 125 132
-
(2001)
Cancer Biother Radiopharm
, vol.16
, pp. 125-132
-
-
Posey, J.A.1
Khazaeli, M.B.2
Delgrosso, A.3
Saleh, M.N.4
Lin, C.Y.5
Huse, W.6
-
137
-
-
77953292291
-
Tissue factor mediates the HGF/Met-induced anti-apoptotic pathway in DAOY medulloblastoma cells
-
M. Provencal, N. Berger-Thibault, D. Labbe, R. Veitch, D. Boivin, and G.E. Rivard Tissue factor mediates the HGF/Met-induced anti-apoptotic pathway in DAOY medulloblastoma cells J Neurooncol 97 2010 365 372
-
(2010)
J Neurooncol
, vol.97
, pp. 365-372
-
-
Provencal, M.1
Berger-Thibault, N.2
Labbe, D.3
Veitch, R.4
Boivin, D.5
Rivard, G.E.6
-
138
-
-
0025853770
-
Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas
-
C. Pyke, P. Kristensen, E. Ralfkiaer, J. Grondahl-Hansen, J. Eriksen, and F. Blasi Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas Am J Pathol 138 1991 1059 1067
-
(1991)
Am J Pathol
, vol.138
, pp. 1059-1067
-
-
Pyke, C.1
Kristensen, P.2
Ralfkiaer, E.3
Grondahl-Hansen, J.4
Eriksen, J.5
Blasi, F.6
-
139
-
-
42549152045
-
No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
-
W. Qiu, M. Hu, A. Sridhar, K. Opeskin, S. Fox, and M. Shipitsin No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas Nat Genet 40 2008 650 655
-
(2008)
Nat Genet
, vol.40
, pp. 650-655
-
-
Qiu, W.1
Hu, M.2
Sridhar, A.3
Opeskin, K.4
Fox, S.5
Shipitsin, M.6
-
140
-
-
0036178475
-
Order and disorder: The role of extracellular matrix in epithelial cancer
-
D. Radisky, J. Muschler, and M.J. Bissell Order and disorder: the role of extracellular matrix in epithelial cancer Cancer Invest 20 2002 139 153
-
(2002)
Cancer Invest
, vol.20
, pp. 139-153
-
-
Radisky, D.1
Muschler, J.2
Bissell, M.J.3
-
141
-
-
34948884579
-
Stromal induction of breast cancer: Inflammation and invasion
-
E.S. Radisky, and D.C. Radisky Stromal induction of breast cancer: inflammation and invasion Rev Endocr Metab Disord 8 2007 279 287
-
(2007)
Rev Endocr Metab Disord
, vol.8
, pp. 279-287
-
-
Radisky, E.S.1
Radisky, D.C.2
-
142
-
-
77956883321
-
Activation of fibroblasts in cancer stroma
-
K. Rasanen, and A. Vaheri Activation of fibroblasts in cancer stroma Exp Cell Res 316 2010 2713 2722
-
(2010)
Exp Cell Res
, vol.316
, pp. 2713-2722
-
-
Rasanen, K.1
Vaheri, A.2
-
143
-
-
75149183984
-
Extracellular cleavage and shedding of P-cadherin: A mechanism underlying the invasive behaviour of breast cancer cells
-
A.S. Ribeiro, A. Albergaria, B. Sousa, A.L. Correia, M. Bracke, and R. Seruca Extracellular cleavage and shedding of P-cadherin: a mechanism underlying the invasive behaviour of breast cancer cells Oncogene 29 2010 392 402
-
(2010)
Oncogene
, vol.29
, pp. 392-402
-
-
Ribeiro, A.S.1
Albergaria, A.2
Sousa, B.3
Correia, A.L.4
Bracke, M.5
Seruca, R.6
-
144
-
-
59449094255
-
Volociximab, a chimeric monoclonal antibody that specifically binds alpha5beta1 integrin: A phase I, pharmacokinetic, and biological correlative study
-
A.D. Ricart, A.W. Tolcher, G. Liu, K. Holen, G. Schwartz, and M. Albertini Volociximab, a chimeric monoclonal antibody that specifically binds alpha5beta1 integrin: a phase I, pharmacokinetic, and biological correlative study Clin Cancer Res 14 2008 7924 7929
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7924-7929
-
-
Ricart, A.D.1
Tolcher, A.W.2
Liu, G.3
Holen, K.4
Schwartz, G.5
Albertini, M.6
-
145
-
-
36649011014
-
Global expression analysis of prostate cancer-associated stroma and epithelia
-
A.M. Richardson, K. Woodson, Y. Wang, J. Rodriguez-Canales, H.S. Erickson, and M.A. Tangrea Global expression analysis of prostate cancer-associated stroma and epithelia Diagn Mol Pathol 16 2007 189 197
-
(2007)
Diagn Mol Pathol
, vol.16
, pp. 189-197
-
-
Richardson, A.M.1
Woodson, K.2
Wang, Y.3
Rodriguez-Canales, J.4
Erickson, H.S.5
Tangrea, M.A.6
-
146
-
-
33847407954
-
Identification of a unique epigenetic sub-microenvironment in prostate cancer
-
J. Rodriguez-Canales, J.C. Hanson, M.A. Tangrea, H.S. Erickson, P.S. Albert, and B.S. Wallis Identification of a unique epigenetic sub-microenvironment in prostate cancer J Pathol 211 2007 410 419
-
(2007)
J Pathol
, vol.211
, pp. 410-419
-
-
Rodriguez-Canales, J.1
Hanson, J.C.2
Tangrea, M.A.3
Erickson, H.S.4
Albert, P.S.5
Wallis, B.S.6
-
147
-
-
0027161705
-
Induction of alpha-smooth muscle actin by transforming growth factor-β1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia
-
L. Ronnov-Jessen, and O.W. Petersen Induction of alpha-smooth muscle actin by transforming growth factor-β1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia Lab Invest 68 1993 696 707
-
(1993)
Lab Invest
, vol.68
, pp. 696-707
-
-
Ronnov-Jessen, L.1
Petersen, O.W.2
-
148
-
-
0028890174
-
The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells
-
L. Ronnov-Jessen, O.W. Petersen, V.E. Koteliansky, and M.J. Bissell The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells J Clin Invest 95 1995 859 873
-
(1995)
J Clin Invest
, vol.95
, pp. 859-873
-
-
Ronnov-Jessen, L.1
Petersen, O.W.2
Koteliansky, V.E.3
Bissell, M.J.4
-
149
-
-
33750088190
-
Isoform-specific regulation of the actin-organizing protein palladin during TGF-β1-induced myofibroblast differentiation
-
M.J. Ronty, S.K. Leivonen, B. Hinz, A. Rachlin, C.A. Otey, and V.M. Kahari Isoform-specific regulation of the actin-organizing protein palladin during TGF-β1-induced myofibroblast differentiation J Invest Dermatol 126 2006 2387 2396
-
(2006)
J Invest Dermatol
, vol.126
, pp. 2387-2396
-
-
Ronty, M.J.1
Leivonen, S.K.2
Hinz, B.3
Rachlin, A.4
Otey, C.A.5
Kahari, V.M.6
-
150
-
-
78650825618
-
Effect of daily aspirin on long-term risk of death due to cancer: Analysis of individual patient data from randomised trials
-
P.M. Rothwell, F.G. Fowkes, J.F. Belch, H. Ogawa, C.P. Warlow, and T.W. Meade Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials Lancet 377 2011 31 41
-
(2011)
Lancet
, vol.377
, pp. 31-41
-
-
Rothwell, P.M.1
Fowkes, F.G.2
Belch, J.F.3
Ogawa, H.4
Warlow, C.P.5
Meade, T.W.6
-
151
-
-
79952035675
-
Cancer-associated fibroblasts correlate with poor prognosis in rectal cancer after chemoradiotherapy
-
S. Saigusa, Y. Toiyama, K. Tanaka, T. Yokoe, Y. Okugawa, and H. Fujikawa Cancer-associated fibroblasts correlate with poor prognosis in rectal cancer after chemoradiotherapy Int J Oncol 38 2011 655 663
-
(2011)
Int J Oncol
, vol.38
, pp. 655-663
-
-
Saigusa, S.1
Toiyama, Y.2
Tanaka, K.3
Yokoe, T.4
Okugawa, Y.5
Fujikawa, H.6
-
152
-
-
16544380358
-
Novel sensitizing agents: Potential contribution of COX-2 inhibitor for endocrine therapy of breast cancer
-
S. Saji, M. Hirose, and M. Toi Novel sensitizing agents: potential contribution of COX-2 inhibitor for endocrine therapy of breast cancer Breast Cancer 11 2004 129 133
-
(2004)
Breast Cancer
, vol.11
, pp. 129-133
-
-
Saji, S.1
Hirose, M.2
Toi, M.3
-
153
-
-
33751579930
-
Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma
-
A.V. Salnikov, N.E. Heldin, L.B. Stuhr, H. Wiig, H. Gerber, and R.K. Reed Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma Int J Cancer 119 2006 2795 2802
-
(2006)
Int J Cancer
, vol.119
, pp. 2795-2802
-
-
Salnikov, A.V.1
Heldin, N.E.2
Stuhr, L.B.3
Wiig, H.4
Gerber, H.5
Reed, R.K.6
-
154
-
-
4944265244
-
Gene expression profiling of tumor-stromal interactions between pancreatic cancer cells and stromal fibroblasts
-
N. Sato, N. Maehara, and M. Goggins Gene expression profiling of tumor-stromal interactions between pancreatic cancer cells and stromal fibroblasts Cancer Res 64 2004 6950 6956
-
(2004)
Cancer Res
, vol.64
, pp. 6950-6956
-
-
Sato, N.1
Maehara, N.2
Goggins, M.3
-
155
-
-
79955870488
-
Cancer-associated fibroblasts and their putative role in potentiating the initiation and development of epithelial ovarian cancer
-
I.G. Schauer, A.K. Sood, S. Mok, and J. Liu Cancer-associated fibroblasts and their putative role in potentiating the initiation and development of
-
(2011)
Neoplasia
, vol.13
, pp. 393-405
-
-
Schauer, I.G.1
Sood, A.K.2
Mok, S.3
Liu, J.4
-
156
-
-
79956217912
-
Transforming growth factor-β2 gene silencing with trabedersen (AP 12009) in pancreatic cancer
-
K.H. Schlingensiepen, F. Jaschinski, S.A. Lang, C. Moser, E.K. Geissler, and H.J. Schlitt Transforming growth factor-β2 gene silencing with trabedersen (AP 12009) in pancreatic cancer Cancer Sci 102 2011 1193 1200
-
(2011)
Cancer Sci
, vol.102
, pp. 1193-1200
-
-
Schlingensiepen, K.H.1
Jaschinski, F.2
Lang, S.A.3
Moser, C.4
Geissler, E.K.5
Schlitt, H.J.6
-
157
-
-
79960209125
-
Cancer therapy trials employing level-of-evidence-1 disease forecast cancer biomarkers uPA and its inhibitor PAI-1
-
M. Schmitt, N. Harbeck, N. Brunner, F. Janicke, C. Meisner, and B. Muhlenweg Cancer therapy trials employing level-of-evidence-1 disease forecast cancer biomarkers uPA and its inhibitor PAI-1 Expert Rev Mol Diagn 11 2011 617 634
-
(2011)
Expert Rev Mol Diagn
, vol.11
, pp. 617-634
-
-
Schmitt, M.1
Harbeck, N.2
Brunner, N.3
Janicke, F.4
Meisner, C.5
Muhlenweg, B.6
-
158
-
-
78649277216
-
Clinical utility of level-of-evidence-1 disease forecast cancer biomarkers uPA and its inhibitor PAI-1
-
M. Schmitt, K. Mengele, R. Napieralski, V. Magdolen, U. Reuning, and A. Gkazepis Clinical utility of level-of-evidence-1 disease forecast cancer biomarkers uPA and its inhibitor PAI-1 Expert Rev Mol Diagn 10 2010 1051 1067
-
(2010)
Expert Rev Mol Diagn
, vol.10
, pp. 1051-1067
-
-
Schmitt, M.1
Mengele, K.2
Napieralski, R.3
Magdolen, V.4
Reuning, U.5
Gkazepis, A.6
-
159
-
-
0037989982
-
A Phase i dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer
-
A.M. Scott, G. Wiseman, S. Welt, A. Adjei, F.T. Lee, and W. Hopkins A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer Clin Cancer Res 9 2003 1639 1647
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1639-1647
-
-
Scott, A.M.1
Wiseman, G.2
Welt, S.3
Adjei, A.4
Lee, F.T.5
Hopkins, W.6
-
160
-
-
76249126427
-
Rationale for the development of IMC-3G3, a fully human immunoglobulin G subclass 1 monoclonal antibody targeting the platelet-derived growth factor receptor alpha
-
G.D. Shah, N. Loizos, H. Youssoufian, J.D. Schwartz, and E.K. Rowinsky Rationale for the development of IMC-3G3, a fully human immunoglobulin G subclass 1 monoclonal antibody targeting the platelet-derived growth factor receptor alpha Cancer 116 2010 1018 1026
-
(2010)
Cancer
, vol.116
, pp. 1018-1026
-
-
Shah, G.D.1
Loizos, N.2
Youssoufian, H.3
Schwartz, J.D.4
Rowinsky, E.K.5
-
162
-
-
0037613824
-
Tumor-associated fibroblasts recruit blood monocytes into tumor tissue
-
T. Silzle, M. Kreutz, M.A. Dobler, G. Brockhoff, R. Knuechel, and L.A. Kunz-Schughart Tumor-associated fibroblasts recruit blood monocytes into tumor tissue Eur J Immunol 33 2003 1311 1320
-
(2003)
Eur J Immunol
, vol.33
, pp. 1311-1320
-
-
Silzle, T.1
Kreutz, M.2
Dobler, M.A.3
Brockhoff, G.4
Knuechel, R.5
Kunz-Schughart, L.A.6
-
163
-
-
0348012943
-
The fibroblast: Sentinel cell and local immune modulator in tumor tissue
-
T. Silzle, G.J. Randolph, M. Kreutz, and L.A. Kunz-Schughart The fibroblast: sentinel cell and local immune modulator in tumor tissue Int J Cancer 108 2004 173 180
-
(2004)
Int J Cancer
, vol.108
, pp. 173-180
-
-
Silzle, T.1
Randolph, G.J.2
Kreutz, M.3
Kunz-Schughart, L.A.4
-
164
-
-
0036209979
-
MMP-2 and MMP-9 expression in breast cancer-derived human fibroblasts is differentially regulated by stromal-epithelial interactions
-
C.F. Singer, N. Kronsteiner, E. Marton, M. Kubista, K.J. Cullen, and K. Hirtenlehner MMP-2 and MMP-9 expression in breast cancer-derived human fibroblasts is differentially regulated by stromal-epithelial interactions Breast Cancer Res Treat 72 2002 69 77
-
(2002)
Breast Cancer Res Treat
, vol.72
, pp. 69-77
-
-
Singer, C.F.1
Kronsteiner, N.2
Marton, E.3
Kubista, M.4
Cullen, K.J.5
Hirtenlehner, K.6
-
165
-
-
79955506852
-
The IL-8-regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth
-
R.K. Singh, and B.L. Lokeshwar The IL-8-regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth Cancer Res 71 2011 3268 3277
-
(2011)
Cancer Res
, vol.71
, pp. 3268-3277
-
-
Singh, R.K.1
Lokeshwar, B.L.2
-
166
-
-
78650194206
-
CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: A novel target for therapy
-
S. Singh, S.K. Srivastava, A. Bhardwaj, L.B. Owen, and A.P. Singh CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy Br J Cancer 103 2010 1671 1679
-
(2010)
Br J Cancer
, vol.103
, pp. 1671-1679
-
-
Singh, S.1
Srivastava, S.K.2
Bhardwaj, A.3
Owen, L.B.4
Singh, A.P.5
-
167
-
-
11244304302
-
Desmoplasia measured by computer assisted image analysis: An independent prognostic marker in colorectal carcinoma
-
B. Sis, S. Sarioglu, S. Sokmen, M. Sakar, A. Kupelioglu, and M. Fuzun Desmoplasia measured by computer assisted image analysis: an independent prognostic marker in colorectal carcinoma J Clin Pathol 58 2005 32 38
-
(2005)
J Clin Pathol
, vol.58
, pp. 32-38
-
-
Sis, B.1
Sarioglu, S.2
Sokmen, S.3
Sakar, M.4
Kupelioglu, A.5
Fuzun, M.6
-
168
-
-
9244234390
-
CXCR4 regulates growth of both primary and metastatic breast cancer
-
M.C. Smith, K.E. Luker, J.R. Garbow, J.L. Prior, E. Jackson, and D. Piwnica-Worms CXCR4 regulates growth of both primary and metastatic breast cancer Cancer Res 64 2004 8604 8612
-
(2004)
Cancer Res
, vol.64
, pp. 8604-8612
-
-
Smith, M.C.1
Luker, K.E.2
Garbow, J.R.3
Prior, J.L.4
Jackson, E.5
Piwnica-Worms, D.6
-
169
-
-
33144462553
-
Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752
-
G.A. Smolen, R. Sordella, B. Muir, G. Mohapatra, A. Barmettler, and H. Archibald Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752 Proc Natl Acad Sci U S A 103 2006 2316 2321
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2316-2321
-
-
Smolen, G.A.1
Sordella, R.2
Muir, B.3
Mohapatra, G.4
Barmettler, A.5
Archibald, H.6
-
170
-
-
66849138510
-
Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells
-
J.W. Song, S.P. Cavnar, A.C. Walker, K.E. Luker, M. Gupta, and Y.C. Tung Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells PLoS One 4 2009 e5756
-
(2009)
PLoS One
, vol.4
, pp. 5756
-
-
Song, J.W.1
Cavnar, S.P.2
Walker, A.C.3
Luker, K.E.4
Gupta, M.5
Tung, Y.C.6
-
171
-
-
60549103300
-
Highly variable response to cytotoxic chemotherapy in carcinoma-associated fibroblasts (CAFs) from lung and breast
-
M. Sonnenberg, H. van der Kuip, S. Haubeis, P. Fritz, W. Schroth, and G. Friedel Highly variable response to cytotoxic chemotherapy in carcinoma-associated fibroblasts (CAFs) from lung and breast BMC Cancer 8 2008 364
-
(2008)
BMC Cancer
, vol.8
, pp. 364
-
-
Sonnenberg, M.1
Van Der Kuip, H.2
Haubeis, S.3
Fritz, P.4
Schroth, W.5
Friedel, G.6
-
172
-
-
16544372352
-
Randomized phase III trial of marimastat versus placebo in patients with metastatic breast cancer who have responding or stable disease after first-line chemotherapy: Eastern Cooperative Oncology Group trial E2196
-
J.A. Sparano, P. Bernardo, P. Stephenson, W.J. Gradishar, J.N. Ingle, and S. Zucker Randomized phase III trial of marimastat versus placebo in patients with metastatic breast cancer who have responding or stable disease after first-line chemotherapy: Eastern Cooperative Oncology Group trial E2196 J Clin Oncol 22 2004 4683 4690
-
(2004)
J Clin Oncol
, vol.22
, pp. 4683-4690
-
-
Sparano, J.A.1
Bernardo, P.2
Stephenson, P.3
Gradishar, W.J.4
Ingle, J.N.5
Zucker, S.6
-
173
-
-
39249085072
-
Role of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) for prognosis in endometrial cancer
-
E. Steiner, K. Pollow, D. Hasenclever, W. Schormann, M. Hermes, and M. Schmidt Role of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) for prognosis in endometrial cancer Gynecol Oncol 108 2008 569 576
-
(2008)
Gynecol Oncol
, vol.108
, pp. 569-576
-
-
Steiner, E.1
Pollow, K.2
Hasenclever, D.3
Schormann, W.4
Hermes, M.5
Schmidt, M.6
-
174
-
-
0029961995
-
Regulation of basic fibroblast growth factor expression by transforming growth factor beta in cultured human prostate stromal cells
-
M.T. Story, K.A. Hopp, and D.A. Meier Regulation of basic fibroblast growth factor expression by transforming growth factor beta in cultured human prostate stromal cells Prostate 28 1996 219 226
-
(1996)
Prostate
, vol.28
, pp. 219-226
-
-
Story, M.T.1
Hopp, K.A.2
Meier, D.A.3
-
175
-
-
77953748064
-
Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-β mediated mechanism in a mouse xenograft model of breast cancer
-
C.H. Stuelten, J.I. Busch, B. Tang, K.C. Flanders, A. Oshima, and E. Sutton Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-β mediated mechanism in a mouse xenograft model of breast cancer PLoS One 5 2010 e9832
-
(2010)
PLoS One
, vol.5
, pp. 9832
-
-
Stuelten, C.H.1
Busch, J.I.2
Tang, B.3
Flanders, K.C.4
Oshima, A.5
Sutton, E.6
-
176
-
-
77957056581
-
Vascular endothelial growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
-
J. Subramanian, D. Morgensztern, and R. Govindan Vascular endothelial growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer Clin Lung Cancer 11 2010 311 319
-
(2010)
Clin Lung Cancer
, vol.11
, pp. 311-319
-
-
Subramanian, J.1
Morgensztern, D.2
Govindan, R.3
-
177
-
-
33846967113
-
Identification of fibroblast heterogeneity in the tumor microenvironment
-
H. Sugimoto, T.M. Mundel, M.W. Kieran, and R. Kalluri Identification of fibroblast heterogeneity in the tumor microenvironment Cancer Biol Ther 5 2006 1640 1646
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 1640-1646
-
-
Sugimoto, H.1
Mundel, T.M.2
Kieran, M.W.3
Kalluri, R.4
-
178
-
-
79952464314
-
Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model
-
T. Sumida, Y. Kitadai, K. Shinagawa, M. Tanaka, M. Kodama, and M. Ohnishi Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model Int J Cancer 128 2011 2050 2062
-
(2011)
Int J Cancer
, vol.128
, pp. 2050-2062
-
-
Sumida, T.1
Kitadai, Y.2
Shinagawa, K.3
Tanaka, M.4
Kodama, M.5
Ohnishi, M.6
-
179
-
-
0142102523
-
T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer
-
H. Tamamura, A. Hori, N. Kanzaki, K. Hiramatsu, M. Mizumoto, and H. Nakashima T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer FEBS Lett 550 2003 79 83
-
(2003)
FEBS Lett
, vol.550
, pp. 79-83
-
-
Tamamura, H.1
Hori, A.2
Kanzaki, N.3
Hiramatsu, K.4
Mizumoto, M.5
Nakashima, H.6
-
180
-
-
34249340106
-
Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice
-
K. Taniwaki, H. Fukamachi, K. Komori, Y. Ohtake, T. Nonaka, and T. Sakamoto Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice Cancer Res 67 2007 4311 4319
-
(2007)
Cancer Res
, vol.67
, pp. 4311-4319
-
-
Taniwaki, K.1
Fukamachi, H.2
Komori, K.3
Ohtake, Y.4
Nonaka, T.5
Sakamoto, T.6
-
181
-
-
23844504745
-
Association of interleukin-8 and plasminogen activator system in the progression of colorectal cancer
-
H. Terada, T. Urano, and H. Konno Association of interleukin-8 and plasminogen activator system in the progression of colorectal cancer Eur Surg Res 37 2005 166 172
-
(2005)
Eur Surg Res
, vol.37
, pp. 166-172
-
-
Terada, H.1
Urano, T.2
Konno, H.3
-
182
-
-
0038823614
-
Myofibroblast differentiation by transforming growth factor-β1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase
-
V.J. Thannickal, D.Y. Lee, E.S. White, Z. Cui, J.M. Larios, and R. Chacon Myofibroblast differentiation by transforming growth factor-β1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase J Biol Chem 278 2003 12384 12389
-
(2003)
J Biol Chem
, vol.278
, pp. 12384-12389
-
-
Thannickal, V.J.1
Lee, D.Y.2
White, E.S.3
Cui, Z.4
Larios, J.M.5
Chacon, R.6
-
183
-
-
84859889031
-
Co-expression of hepatocyte growth factor and c-Met predicts peritoneal dissemination established by autocrine hepatocyte growth factor/c-Met signaling in gastric cancer
-
Y. Toiyama, H. Yasuda, S. Saigusa, K. Matushita, H. Fujikawa, and K. Tanaka Co-expression of hepatocyte growth factor and c-Met predicts peritoneal dissemination established by autocrine hepatocyte growth factor/c-Met signaling in gastric cancer Int J Cancer 130 2012 2912 2921
-
(2012)
Int J Cancer
, vol.130
, pp. 2912-2921
-
-
Toiyama, Y.1
Yasuda, H.2
Saigusa, S.3
Matushita, K.4
Fujikawa, H.5
Tanaka, K.6
-
184
-
-
0035067626
-
C-MET expression in myofibroblasts: Role in autocrine activation and prognostic significance in lung adenocarcinoma
-
M. Tokunou, T. Niki, K. Eguchi, S. Iba, H. Tsuda, and T. Yamada c-MET expression in myofibroblasts: role in autocrine activation and prognostic significance in lung adenocarcinoma Am J Pathol 158 2001 1451 1463
-
(2001)
Am J Pathol
, vol.158
, pp. 1451-1463
-
-
Tokunou, M.1
Niki, T.2
Eguchi, K.3
Iba, S.4
Tsuda, H.5
Yamada, T.6
-
185
-
-
70350510924
-
Pten in stromal fibroblasts suppresses mammary epithelial tumours
-
A.J. Trimboli, C.Z. Cantemir-Stone, F. Li, J.A. Wallace, A. Merchant, and N. Creasap Pten in stromal fibroblasts suppresses mammary epithelial tumours Nature 461 2009 1084 1091
-
(2009)
Nature
, vol.461
, pp. 1084-1091
-
-
Trimboli, A.J.1
Cantemir-Stone, C.Z.2
Li, F.3
Wallace, J.A.4
Merchant, A.5
Creasap, N.6
-
186
-
-
34247503111
-
Stromal myofibroblasts predict disease recurrence for colorectal cancer
-
T. Tsujino, I. Seshimo, H. Yamamoto, C.Y. Ngan, K. Ezumi, and I. Takemasa Stromal myofibroblasts predict disease recurrence for colorectal cancer Clin Cancer Res 13 2007 2082 2090
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2082-2090
-
-
Tsujino, T.1
Seshimo, I.2
Yamamoto, H.3
Ngan, C.Y.4
Ezumi, K.5
Takemasa, I.6
-
187
-
-
33747484487
-
Frequent gene dosage alterations in stromal cells of epithelial ovarian carcinomas
-
H. Tuhkanen, M. Anttila, V.M. Kosma, S. Heinonen, M. Juhola, and S. Helisalmi Frequent gene dosage alterations in stromal cells of epithelial ovarian carcinomas Int J Cancer 119 2006 1345 1353
-
(2006)
Int J Cancer
, vol.119
, pp. 1345-1353
-
-
Tuhkanen, H.1
Anttila, M.2
Kosma, V.M.3
Heinonen, S.4
Juhola, M.5
Helisalmi, S.6
-
188
-
-
79251586559
-
Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis
-
S.W. Tyan, W.H. Kuo, C.K. Huang, C.C. Pan, J.Y. Shew, and K.J. Chang Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis PLoS One 6 2011 e15313
-
(2011)
PLoS One
, vol.6
, pp. 15313
-
-
Tyan, S.W.1
Kuo, W.H.2
Huang, C.K.3
Pan, C.C.4
Shew, J.Y.5
Chang, K.J.6
-
189
-
-
0031828490
-
Antisense oligonucleotide specific for transforming growth factor-β1 inhibit both in vitro and in vivo growth of MBT-2 murine bladder cancer
-
T.S. Tzai, C.I. Lin, A.L. Shiau, and C.L. Wu Antisense oligonucleotide specific for transforming growth factor-β1 inhibit both in vitro and in vivo growth of MBT-2 murine bladder cancer Anticancer Res 18 1998 1585 1589
-
(1998)
Anticancer Res
, vol.18
, pp. 1585-1589
-
-
Tzai, T.S.1
Lin, C.I.2
Shiau, A.L.3
Wu, C.L.4
-
190
-
-
10944232632
-
Profiling molecular targets of TGF-β1 in prostate fibroblast-to-myofibroblast transdifferentiation
-
G. Untergasser, R. Gander, C. Lilg, G. Lepperdinger, E. Plas, and P. Berger Profiling molecular targets of TGF-β1 in prostate fibroblast-to-myofibroblast transdifferentiation Mech Ageing Dev 126 2005 59 69
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 59-69
-
-
Untergasser, G.1
Gander, R.2
Lilg, C.3
Lepperdinger, G.4
Plas, E.5
Berger, P.6
-
191
-
-
70449636444
-
Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge
-
F. van Zijl, M. Mair, A. Csiszar, D. Schneller, G. Zulehner, and H. Huber Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge Oncogene 28 2009 4022 4033
-
(2009)
Oncogene
, vol.28
, pp. 4022-4033
-
-
Van Zijl, F.1
Mair, M.2
Csiszar, A.3
Schneller, D.4
Zulehner, G.5
Huber, H.6
-
193
-
-
55149113365
-
Pancreatic cancer associated fibroblasts display normal allelotypes
-
K. Walter, N. Omura, S.M. Hong, M. Griffith, and M. Goggins Pancreatic cancer associated fibroblasts display normal allelotypes Cancer Biol Ther 7 2008 882 888
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 882-888
-
-
Walter, K.1
Omura, N.2
Hong, S.M.3
Griffith, M.4
Goggins, M.5
-
194
-
-
77953725367
-
Emerging roles of PDGF-D signaling pathway in tumor development and progression
-
Z. Wang, A. Ahmad, Y. Li, D. Kong, A.S. Azmi, and S. Banerjee Emerging roles of PDGF-D signaling pathway in tumor development and progression Biochim Biophys Acta 1806 2010 122 130
-
(2010)
Biochim Biophys Acta
, vol.1806
, pp. 122-130
-
-
Wang, Z.1
Ahmad, A.2
Li, Y.3
Kong, D.4
Azmi, A.S.5
Banerjee, S.6
-
195
-
-
42949133032
-
The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer
-
J. Wang, Y. Shiozawa, Y. Wang, Y. Jung, K.J. Pienta, and R. Mehra The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer J Biol Chem 283 2008 4283 4294
-
(2008)
J Biol Chem
, vol.283
, pp. 4283-4294
-
-
Wang, J.1
Shiozawa, Y.2
Wang, Y.3
Jung, Y.4
Pienta, K.J.5
Mehra, R.6
-
196
-
-
33846144441
-
Microenvironmental genomic alterations and clinicopathological behavior in head and neck squamous cell carcinoma
-
F. Weber, Y. Xu, L. Zhang, A. Patocs, L. Shen, and P. Platzer Microenvironmental genomic alterations and clinicopathological behavior in head and neck squamous cell carcinoma JAMA 297 2007 187 195
-
(2007)
JAMA
, vol.297
, pp. 187-195
-
-
Weber, F.1
Xu, Y.2
Zhang, L.3
Patocs, A.4
Shen, L.5
Platzer, P.6
-
198
-
-
84983735948
-
Lysyl oxidase, extracellular matrix remodeling and cancer metastasis
-
10.1007/s12307-012-0105-z
-
Q. Xiao, and G. Ge Lysyl oxidase, extracellular matrix remodeling and cancer metastasis Cancer Microenviron 2012 10.1007/s12307-012-0105-z
-
(2012)
Cancer Microenviron
-
-
Xiao, Q.1
Ge, G.2
-
199
-
-
75849124916
-
Origin and function of tumor stroma fibroblasts
-
G. Xouri, and S. Christian Origin and function of tumor stroma fibroblasts Semin Cell Dev Biol 21 2010 40 46
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 40-46
-
-
Xouri, G.1
Christian, S.2
-
200
-
-
33750798741
-
The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
-
G. Yang, D.G. Rosen, Z. Zhang, R.C. Bast Jr., G.B. Mills, and J.A. Colacino The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis Proc Natl Acad Sci U S A 103 2006 16472 16477
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 16472-16477
-
-
Yang, G.1
Rosen, D.G.2
Zhang, Z.3
Bast, Jr.R.C.4
Mills, G.B.5
Colacino, J.A.6
-
201
-
-
0034650486
-
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis
-
Q. Yu, and I. Stamenkovic Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis Genes Dev 14 2000 163 176
-
(2000)
Genes Dev
, vol.14
, pp. 163-176
-
-
Yu, Q.1
Stamenkovic, I.2
-
202
-
-
35948945337
-
Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts
-
E.M. Zeisberg, S. Potenta, L. Xie, M. Zeisberg, and R. Kalluri Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts Cancer Res 67 2007 10123 10128
-
(2007)
Cancer Res
, vol.67
, pp. 10123-10128
-
-
Zeisberg, E.M.1
Potenta, S.2
Xie, L.3
Zeisberg, M.4
Kalluri, R.5
|