메뉴 건너뛰기




Volumn 5, Issue 3, 2010, Pages

Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-b Mediated Mechanism in a Mouse Xenograft Model of Breast Cancer

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

EID: 77953748064     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009832     Document Type: Article
Times cited : (81)

References (48)
  • 1
    • 23744432972 scopus 로고    scopus 로고
    • Stromagenesis: The changing face of fibroblastic microenvironments during tumor progression
    • Beacham DA, Cukierman E (2005) Stromagenesis: the changing face of fibroblastic microenvironments during tumor progression. SeminCancer Biol 15: 329-341.
    • (2005) SeminCancer Biol , vol.15 , pp. 329-341
    • Beacham, D.A.1    Cukierman, E.2
  • 2
    • 25444457480 scopus 로고    scopus 로고
    • Stroma: Tumor agonist or antagonist
    • Proia DA, Kuperwasser C (2005) Stroma: tumor agonist or antagonist. Cell Cycle 4: 1022-1025.
    • (2005) Cell Cycle , vol.4 , pp. 1022-1025
    • Proia, D.A.1    Kuperwasser, C.2
  • 3
    • 0033215242 scopus 로고    scopus 로고
    • Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
    • Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, et al. (1999) Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 59: 5002-5011.
    • (1999) Cancer Res , vol.59 , pp. 5002-5011
    • Olumi, A.F.1    Grossfeld, G.D.2    Hayward, S.W.3    Carroll, P.R.4    Tlsty, T.D.5
  • 4
    • 0035902141 scopus 로고    scopus 로고
    • The microenvironment of the tumour-host interface
    • Liotta LA, Kohn EC (2001) The microenvironment of the tumour-host interface. Nature 411: 375-379.
    • (2001) Nature , vol.411 , pp. 375-379
    • Liotta, L.A.1    Kohn, E.C.2
  • 5
    • 33747598447 scopus 로고    scopus 로고
    • More than structural cells, fibroblasts create and orchestrate the tumor microenvironment
    • Baglole CJ, Ray DM, Bernstein SH, Feldon SE, Smith TJ, et al. (2006) More than structural cells, fibroblasts create and orchestrate the tumor microenvironment. ImmunolInvest 35: 297-325.
    • (2006) ImmunolInvest , vol.35 , pp. 297-325
    • Baglole, C.J.1    Ray, D.M.2    Bernstein, S.H.3    Feldon, S.E.4    Smith, T.J.5
  • 6
    • 28844444157 scopus 로고    scopus 로고
    • Exploring the tumour environment: Cancerassociated fibroblasts as targets in cancer therapy
    • Micke P, Ostman A (2005) Exploring the tumour environment: cancerassociated fibroblasts as targets in cancer therapy. ExpertOpinTherTargets 9: 1217-1233.
    • (2005) ExpertOpinTherTargets , vol.9 , pp. 1217-1233
    • Micke, P.1    Ostman, A.2
  • 7
    • 1842687362 scopus 로고    scopus 로고
    • Reconstruction of functionally normal and malignant human breast tissues in mice
    • Kuperwasser C, Chavarria T, Wu M, Magrane G, Gray JW, et al. (2004) Reconstruction of functionally normal and malignant human breast tissues in mice. ProcNatlAcadSciUSA 101: 4966-4971.
    • (2004) ProcNatlAcadSciUSA , vol.101 , pp. 4966-4971
    • Kuperwasser, C.1    Chavarria, T.2    Wu, M.3    Magrane, G.4    Gray, J.W.5
  • 9
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
    • Campisi J (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120: 513-522.
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 10
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo A, Gupta PB, Sgroi DC, Renzana-Seisdedos F, Delaunay T, et al. (2005) Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121: 335-348.
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Renzana-Seisdedos, F.4    Delaunay, T.5
  • 13
    • 0034574298 scopus 로고    scopus 로고
    • How cells read TGF-beta signals
    • Massague J (2000) How cells read TGF-beta signals. NatRevMolCell Biol 1: 169-178.
    • (2000) NatRevMolCell Biol , vol.1 , pp. 169-178
    • Massague, J.1
  • 14
    • 47549090432 scopus 로고    scopus 로고
    • TGFbeta in Cancer
    • Massague J (2008) TGFbeta in Cancer. Cell 134: 215-230.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massague, J.1
  • 15
    • 0028268417 scopus 로고
    • Mesenchymal-epithelial interactions and transforming growth factor-beta expression during mouse prostate morphogenesis
    • Timme TL, Truong LD, Merz VW, Krebs T, Kadmon D, et al. (1994) Mesenchymal-epithelial interactions and transforming growth factor-beta expression during mouse prostate morphogenesis. Endocrinology 134: 1039-1045.
    • (1994) Endocrinology , vol.134 , pp. 1039-1045
    • Timme, T.L.1    Truong, L.D.2    Merz, V.W.3    Krebs, T.4    Kadmon, D.5
  • 16
    • 0842288323 scopus 로고    scopus 로고
    • TGFbeta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
    • Bhowmick NA, Chytil A, Plieth D, Gorska AE, Dumont N, et al. (2004) TGFbeta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 303: 848-851.
    • (2004) Science , vol.303 , pp. 848-851
    • Bhowmick, N.A.1    Chytil, A.2    Plieth, D.3    Gorska, A.E.4    Dumont, N.5
  • 17
    • 23744452875 scopus 로고    scopus 로고
    • Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP-and HGF-mediated signaling networks
    • Cheng N, Bhowmick NA, Chytil A, Gorksa AE, Brown KA, et al. (2005) Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP-and HGF-mediated signaling networks. Oncogene.
    • (2005) Oncogene
    • Cheng, N.1    Bhowmick, N.A.2    Chytil, A.3    Gorksa, A.E.4    Brown, K.A.5
  • 18
    • 21044440756 scopus 로고    scopus 로고
    • Breast cancer cells induce stromal fibroblasts to express MMP-9 via secretion of TNF-{alpha} and TGF-{beta}
    • Stuelten CH, Byfield SD, Arany PR, Karpova TS, Stetler-Stevenson WG, et al. (2005) Breast cancer cells induce stromal fibroblasts to express MMP-9 via secretion of TNF-{alpha} and TGF-{beta}. JCell Sci 118: 2143-2153.
    • (2005) JCell Sci , vol.118 , pp. 2143-2153
    • Stuelten, C.H.1    Byfield, S.D.2    Arany, P.R.3    Karpova, T.S.4    Stetler-Stevenson, W.G.5
  • 19
    • 20444436815 scopus 로고    scopus 로고
    • Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/ epidermal growth factor paracrine loop
    • Goswami S, Sahai E, Wyckoff JB, Cammer M, Cox D, et al. (2005) Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/ epidermal growth factor paracrine loop. Cancer Res 65: 5278-5283.
    • (2005) Cancer Res , vol.65 , pp. 5278-5283
    • Goswami, S.1    Sahai, E.2    Wyckoff, J.B.3    Cammer, M.4    Cox, D.5
  • 20
    • 23244451640 scopus 로고    scopus 로고
    • Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK
    • Hagemann T, Wilson J, Kulbe H, Li NF, Leinster DA, et al. (2005) Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK. JImmunol 175: 1197-1205.
    • (2005) JImmunol , vol.175 , pp. 1197-1205
    • Hagemann, T.1    Wilson, J.2    Kulbe, H.3    Li, N.F.4    Leinster, D.A.5
  • 21
    • 12144286882 scopus 로고    scopus 로고
    • Mechanisms in epithelial plasticity and metastasis: Insights from 3D cultures and expression profiling
    • Jechlinger M, Grunert S, Beug H (2002) Mechanisms in epithelial plasticity and metastasis: insights from 3D cultures and expression profiling. JMammaryGlandBiolNeoplasia 7: 415-432.
    • (2002) JMammaryGlandBiolNeoplasia , vol.7 , pp. 415-432
    • Jechlinger, M.1    Grunert, S.2    Beug, H.3
  • 22
    • 33644789290 scopus 로고    scopus 로고
    • Stromal cell derived factor-1: Its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer
    • Kang H, Watkins G, Parr C, Douglas-Jones A, Mansel RE, et al. (2005) Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer. Breast Cancer Res 7: R402-R410.
    • (2005) Breast Cancer Res , vol.7
    • Kang, H.1    Watkins, G.2    Parr, C.3    Douglas-Jones, A.4    Mansel, R.E.5
  • 23
    • 0036158686 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha stimulates invasion of Src-activated intestinal cells
    • Kawai N, Tsuji S, Tsujii M, Ito T, Yasumaru M, et al. (2002) Tumor necrosis factor alpha stimulates invasion of Src-activated intestinal cells. Gastroenterology 122: 331-339.
    • (2002) Gastroenterology , vol.122 , pp. 331-339
    • Kawai, N.1    Tsuji, S.2    Tsujii, M.3    Ito, T.4    Yasumaru, M.5
  • 24
    • 1642334157 scopus 로고    scopus 로고
    • Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells
    • Lewis MP, Lygoe KA, Nystrom ML, Anderson WP, Speight PM, et al. (2004) Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells. BrJCancer 90: 822-832.
    • (2004) BrJCancer , vol.90 , pp. 822-832
    • Lewis, M.P.1    Lygoe, K.A.2    Nystrom, M.L.3    Anderson, W.P.4    Speight, P.M.5
  • 25
    • 0027348906 scopus 로고
    • The interaction of HGF-SF with other cytokines in tumor invasion and angiogenesis
    • Rosen EM, Zitnik RJ, Elias JA, Bhargava MM, Wines J, et al. (1993) The interaction of HGF-SF with other cytokines in tumor invasion and angiogenesis. EXS 65: 301-310.
    • (1993) EXS , vol.65 , pp. 301-310
    • Rosen, E.M.1    Zitnik, R.J.2    Elias, J.A.3    Bhargava, M.M.4    Wines, J.5
  • 26
    • 0037037304 scopus 로고    scopus 로고
    • Binding of TGF-beta1 latency-associated peptide (LAP) to alpha(v)beta6 integrin modulates behaviour of squamous carcinoma cells
    • Thomas GJ, Hart IR, Speight PM, Marshall JF (2002) Binding of TGF-beta1 latency-associated peptide (LAP) to alpha(v)beta6 integrin modulates behaviour of squamous carcinoma cells. BrJCancer 87: 859-867.
    • (2002) BrJCancer , vol.87 , pp. 859-867
    • Thomas, G.J.1    Hart, I.R.2    Speight, P.M.3    Marshall, J.F.4
  • 27
    • 27844514155 scopus 로고    scopus 로고
    • Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo
    • Javelaud D, Delmas V, Moller M, Sextius P, Andre J, et al. (2005) Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo. Oncogene 24: 7624-7629.
    • (2005) Oncogene , vol.24 , pp. 7624-7629
    • Javelaud, D.1    Delmas, V.2    Moller, M.3    Sextius, P.4    Andre, J.5
  • 28
    • 0036467496 scopus 로고    scopus 로고
    • TGF-beta signaling: Positive and negative effects on tumorigenesis
    • Wakefield LM, Roberts AB (2002) TGF-beta signaling: positive and negative effects on tumorigenesis. Curr Opin Genet Dev 12: 22-29.
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 22-29
    • Wakefield, L.M.1    Roberts, A.B.2
  • 29
    • 0029551805 scopus 로고
    • Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
    • Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, et al. (1995) Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science 270: 2008-2011.
    • (1995) Science , vol.270 , pp. 2008-2011
    • Yamaguchi, K.1    Shirakabe, K.2    Shibuya, H.3    Irie, K.4    Oishi, I.5
  • 30
    • 33645088428 scopus 로고    scopus 로고
    • Metastasis: Cell-autonomous mechanisms versus contributions by the tumor microenvironment
    • Kopfstein L, Christofori G (2006) Metastasis: cell-autonomous mechanisms versus contributions by the tumor microenvironment. Cell MolLife Sci 63: 449-468.
    • (2006) Cell MolLife Sci , vol.63 , pp. 449-468
    • Kopfstein, L.1    Christofori, G.2
  • 31
    • 33748967069 scopus 로고    scopus 로고
    • Of extracellular matrix, scaffolds, and signaling: Tissue architecture regulates development, homeostasis, and cancer
    • Nelson CM, Bissell MJ (2006) Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer. AnnuRevCell DevBiol 22: 287-309.
    • (2006) AnnuRevCell DevBiol , vol.22 , pp. 287-309
    • Nelson, C.M.1    Bissell, M.J.2
  • 32
    • 34447261691 scopus 로고    scopus 로고
    • A delicate balance: TGF-beta and the tumor microenvironment
    • Stover DG, Bierie B, Moses HL (2007) A delicate balance: TGF-beta and the tumor microenvironment. JCell Biochem 101: 851-861.
    • (2007) JCell Biochem , vol.101 , pp. 851-861
    • Stover, D.G.1    Bierie, B.2    Moses, H.L.3
  • 34
    • 11944255353 scopus 로고
    • Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential
    • Welch DR, Fabra A, Nakajima M (1990) Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential. ProcNatlAcadSciUSA 87: 7678-7682.
    • (1990) ProcNatlAcadSciUSA , vol.87 , pp. 7678-7682
    • Welch, D.R.1    Fabra, A.2    Nakajima, M.3
  • 35
    • 35048875855 scopus 로고    scopus 로고
    • TGF-beta signaling: A tale of two responses
    • Rahimi RA, Leof EB (2007) TGF-beta signaling: a tale of two responses. JCell Biochem 102: 593-608.
    • (2007) JCell Biochem , vol.102 , pp. 593-608
    • Rahimi, R.A.1    Leof, E.B.2
  • 36
    • 42649117445 scopus 로고    scopus 로고
    • Microenvironmental regulation of E-cadherinmediated adherens junctions
    • Giehl K, Menke A (2008) Microenvironmental regulation of E-cadherinmediated adherens junctions. Front Biosci 13: 3975-3985.
    • (2008) Front Biosci , vol.13 , pp. 3975-3985
    • Giehl, K.1    Menke, A.2
  • 37
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • Muller A, Homey B, Soto H, Ge N, Catron D, et al. (2001) Involvement of chemokine receptors in breast cancer metastasis. Nature 410: 50-56.
    • (2001) Nature , vol.410 , pp. 50-56
    • Muller, A.1    Homey, B.2    Soto, H.3    Ge, N.4    Catron, D.5
  • 38
    • 34249295225 scopus 로고    scopus 로고
    • Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium
    • Ao M, Franco OE, Park D, Raman D, Williams K, et al. (2007) Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium. Cancer Res 67: 4244-4253.
    • (2007) Cancer Res , vol.67 , pp. 4244-4253
    • Ao, M.1    Franco, O.E.2    Park, D.3    Raman, D.4    Williams, K.5
  • 40
    • 43249108418 scopus 로고    scopus 로고
    • The TGFBeta pathway as a therapeutic target in cancer
    • Seoane J (2008) The TGFBeta pathway as a therapeutic target in cancer. ClinTranslOncol 10: 14-19.
    • (2008) ClinTranslOncol , vol.10 , pp. 14-19
    • Seoane, J.1
  • 41
    • 0242285692 scopus 로고    scopus 로고
    • TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression
    • Tang B, Vu M, Booker T, Santner SJ, Miller FR, et al. (2003) TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression. JClinInvest 112: 1116-1124.
    • (2003) JClinInvest , vol.112 , pp. 1116-1124
    • Tang, B.1    Vu, M.2    Booker, T.3    Santner, S.J.4    Miller, F.R.5
  • 42
    • 0036124599 scopus 로고    scopus 로고
    • Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation
    • Flanders KC, Sullivan CD, Fujii M, Sowers A, Anzano MA, et al. (2002) Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation. AmJPathol 160: 1057-1068.
    • (2002) AmJPathol , vol.160 , pp. 1057-1068
    • Flanders, K.C.1    Sullivan, C.D.2    Fujii, M.3    Sowers, A.4    Anzano, M.A.5
  • 43
    • 0347626102 scopus 로고    scopus 로고
    • Reduction in smad2/3 signaling enhances tumorigenesis but suppresses metastasis of breast cancer cell lines
    • Tian F, DaCosta BS, Parks WT, Yoo S, Felici A, et al. (2003) Reduction in smad2/3 signaling enhances tumorigenesis but suppresses metastasis of breast cancer cell lines. Cancer Res 63: 8284-8292.
    • (2003) Cancer Res , vol.63 , pp. 8284-8292
    • Tian, F.1    DaCosta, B.S.2    Parks, W.T.3    Yoo, S.4    Felici, A.5
  • 44
    • 34548683671 scopus 로고    scopus 로고
    • Lentiviral reporter constructs for fluorescence tracking of the temporospatial pattern of Smad3 signaling
    • Stuelten CH, Kamaraju AK, Wakefield LM, Roberts AB (2007) Lentiviral reporter constructs for fluorescence tracking of the temporospatial pattern of Smad3 signaling. Biotechniques 43: 289-290, 292, 294.
    • (2007) Biotechniques , vol.43
    • Stuelten, C.H.1    Kamaraju, A.K.2    Wakefield, L.M.3    Roberts, A.B.4
  • 45
    • 3042738106 scopus 로고    scopus 로고
    • Smadbinding defective mutant of transforming growth factor beta type I receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines
    • Tian F, Byfield SD, Parks WT, Stuelten CH, Nemani D, et al. (2004) Smadbinding defective mutant of transforming growth factor beta type I receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines. Cancer Res 64: 4523-4530.
    • (2004) Cancer Res , vol.64 , pp. 4523-4530
    • Tian, F.1    Byfield, S.D.2    Parks, W.T.3    Stuelten, C.H.4    Nemani, D.5
  • 46
    • 0031553962 scopus 로고    scopus 로고
    • Quantification of transforming growth factor-beta in biological material using cells transfected with a plasminogen activator inhibitor-1 promoterluciferase construct
    • van Waarde MA, van Assen AJ, Kampinga HH, Konings AW, Vujaskovic Z (1997) Quantification of transforming growth factor-beta in biological material using cells transfected with a plasminogen activator inhibitor-1 promoterluciferase construct. Anal Biochem 247: 45-51.
    • (1997) Anal Biochem , vol.247 , pp. 45-51
    • van Waarde, M.A.1    van Assen, A.J.2    Kampinga, H.H.3    Konings, A.W.4    Vujaskovic, Z.5
  • 47
    • 54749101955 scopus 로고    scopus 로고
    • Acute wounds accelerate tumorigenesis by a T cell-dependent mechanism
    • Stuelten CH, Barbul A, Busch JI, Sutton E, Katz R, et al. (2008) Acute wounds accelerate tumorigenesis by a T cell-dependent mechanism. Cancer Res 68: 7278-7282.
    • (2008) Cancer Res , vol.68 , pp. 7278-7282
    • Stuelten, C.H.1    Barbul, A.2    Busch, J.I.3    Sutton, E.4    Katz, R.5
  • 48
    • 0028116952 scopus 로고
    • Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene
    • Maroulakou IG, Anver M, Garrett L, Green JE (1994) Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene. Proc Natl Acad Sci U S A 91: 11236-11240.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 11236-11240
    • Maroulakou, I.G.1    Anver, M.2    Garrett, L.3    Green, J.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.