-
2
-
-
66549083540
-
Malignant glioma: Esmo clinical recommendations for diagnosis, treatment and follow-up
-
Stupp R, Roila F. Malignant glioma: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 2009;20(Suppl 4):126e8.
-
(2009)
Ann Oncol
, vol.20
, Issue.SUPPL. 4
-
-
Stupp, R.1
Roila, F.2
-
3
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S, Wu Q, McLendon RE, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006;444:756e60.
-
(2006)
Nature
, vol.444
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
-
4
-
-
77951003656
-
Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States
-
Grossman SA, Ye X, Piantadosi S, et al. Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States. Clin Cancer Res 2010;16:2443e9.
-
(2010)
Clin Cancer Res
, vol.16
-
-
Grossman, S.A.1
Ye, X.2
Piantadosi, S.3
-
5
-
-
73449120734
-
Gene therapy for brain cancer: Combination therapies provide enhanced efficacy and safety
-
Candolfi M, Kroeger KM, Muhammad AK, et al. Gene therapy for brain cancer: combination therapies provide enhanced efficacy and safety. Curr Gene Ther 2009;9:409e21.
-
(2009)
Curr Gene Ther
, vol.9
-
-
Candolfi, M.1
Kroeger, K.M.2
Muhammad, A.K.3
-
7
-
-
0031025998
-
Gene therapy for cancer: What have we done and where are we going?
-
Roth JA, Cristiano RJ. Gene therapy for cancer: what have we done and where are we going? J Natl Cancer Inst 1997;89:21e39.
-
(1997)
J Natl Cancer Inst
, vol.89
-
-
Roth, J.A.1
Cristiano, R.J.2
-
8
-
-
25144436834
-
Gene therapy for malignant glioma: Current clinical status
-
Pulkkanen KJ, Yla-Herttuala S. Gene therapy for malignant glioma: current clinical status. Mol Ther 2005;12:585e98.
-
(2005)
Mol Ther
, vol.12
-
-
Pulkkanen, K.J.1
Yla-Herttuala, S.2
-
9
-
-
10744233353
-
Treatment of progressive or recurrent glioblastoma multiforme in adults with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration: A phase I/II multi-institutional trial
-
Prados MD, McDermott M, Chang SM, et al. Treatment of progressive or recurrent glioblastoma multiforme in adults with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration: a phase I/II multi-institutional trial. J Neurooncol 2003;65:269e78.
-
(2003)
J Neurooncol
, vol.65
-
-
Prados, M.D.1
McDermott, M.2
Chang, S.M.3
-
10
-
-
0034694011
-
A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
-
Rainov NG. A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum Gene Ther 2000;11:2389e401.
-
(2000)
Hum Gene Ther
, vol.11
-
-
Rainov, N.G.1
-
11
-
-
0033588816
-
A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir
-
GLI328 European-Canadian Study Group
-
Shand N, Weber F, Mariani L, et al. A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group. Hum Gene Ther 1999;10:2325e35.
-
(1999)
Hum Gene Ther
, vol.10
-
-
Shand, N.1
Weber, F.2
Mariani, L.3
-
12
-
-
0033000339
-
Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: A pilot study in humans
-
Palu G, Cavaggioni A, Calvi P, et al. Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans. Gene Ther 1999;6:330e7.
-
(1999)
Gene Ther
, vol.6
-
-
Palu, G.1
Cavaggioni, A.2
Calvi, P.3
-
13
-
-
2442767029
-
A phase I/II study of herpes simplex virus type 1 thymidine kinase "Suicide" gene therapy for recurrent glioblastoma. Study group on gene therapy for glioblastoma
-
Klatzmann D, Valery CA, Bensimon G, et al. A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study group on gene therapy for glioblastoma. Hum Gene Ther 1998;9:2595e604.
-
(1998)
Hum Gene Ther
, vol.9
-
-
Klatzmann, D.1
Valery, C.A.2
Bensimon, G.3
-
14
-
-
0029992327
-
Human malignant brain tumor response to herpes simplex thymidine kinase (HSVtk)/ganciclovir gene therapy
-
Izquierdo M, Martin V, de Felipe P, et al. Human malignant brain tumor response to herpes simplex thymidine kinase (HSVtk)/ganciclovir gene therapy. Gene Ther 1996;3:491e5.
-
(1996)
Gene Ther
, vol.3
-
-
Izquierdo, M.1
Martin, V.2
De Felipe, P.3
-
15
-
-
0031463632
-
Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
-
Ram Z, Culver KW, Oshiro EM, et al. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nat Med 1997;3:1354e61.
-
(1997)
Nat Med
, vol.3
-
-
Ram, Z.1
Culver, K.W.2
Oshiro, E.M.3
-
16
-
-
0034136802
-
Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors
-
Trask TW, Trask RP, Aguilar-Cordova E, et al. Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors. Mol Ther 2000;1:195e203.
-
(2000)
Mol Ther
, vol.1
-
-
Trask, T.W.1
Trask, R.P.2
Aguilar-Cordova, E.3
-
17
-
-
0034329438
-
Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses
-
Sandmair AM, Loimas S, Puranen P, et al. Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses. Hum Gene Ther 2000;11:2197e205.
-
(2000)
Hum Gene Ther
, vol.11
-
-
Sandmair, A.M.1
Loimas, S.2
Puranen, P.3
-
18
-
-
0037812853
-
Treatment of relapsed malignant glioma with an adenoviral vector containing the herpes simplex thymidine kinase gene followed by ganciclovir
-
Smitt PS, Driesse M, Wolbers J, et al. Treatment of relapsed malignant glioma with an adenoviral vector containing the herpes simplex thymidine kinase gene followed by ganciclovir. Mol Ther 2003;7:851e8.
-
(2003)
Mol Ther
, vol.7
-
-
Smitt, P.S.1
Driesse, M.2
Wolbers, J.3
-
19
-
-
0346243603
-
Adenovirus/herpes simplex-thymidine kinase/ganciclovir complex: Preliminary results of a phase I trial in patients with recurrent malignant gliomas
-
Germano IM, Fable J, Gultekin SH, et al. Adenovirus/herpes simplex-thymidine kinase/ganciclovir complex: preliminary results of a phase I trial in patients with recurrent malignant gliomas. J Neurooncology 2003;65:279e89.
-
(2003)
J Neurooncology
, vol.65
-
-
Germano, I.M.1
Fable, J.2
Gultekin, S.H.3
-
20
-
-
7044235842
-
AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: A randomised, controlled study
-
Immonen A, Vapalahti M, Tyynela K, et al. AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study. Mol Ther 2004;10:967e72.
-
(2004)
Mol Ther
, vol.10
-
-
Immonen, A.1
Vapalahti, M.2
Tyynela, K.3
-
21
-
-
85047697641
-
Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: Biological and clinical results
-
Lang FF, Bruner JM, Fuller GN, et al. Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results. J Clin Oncol 2003;21:2508e18.
-
(2003)
J Clin Oncol
, vol.21
-
-
Lang, F.F.1
Bruner, J.M.2
Fuller, G.N.3
-
22
-
-
12944315014
-
Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: Results of a phase I trial
-
Markert JM, Medlock MD, Rabkin SD, et al. Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial. Gene Ther 2000;7:867e74.
-
(2000)
Gene Ther
, vol.7
-
-
Markert, J.M.1
Medlock, M.D.2
Rabkin, S.D.3
-
23
-
-
58149237728
-
Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM
-
Markert JM, Liechty PG, Wang W, et al. Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM. Mol Ther 2009;17:199e207.
-
(2009)
Mol Ther
, vol.17
-
-
Markert, J.M.1
Liechty, P.G.2
Wang, W.3
-
24
-
-
85047699172
-
The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: A proof of principle study
-
Papanastassiou V, Rampling R, Fraser M, et al. The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study. Gene Ther 2002;9:398e406.
-
(2002)
Gene Ther
, vol.9
-
-
Papanastassiou, V.1
Rampling, R.2
Fraser, M.3
-
25
-
-
0028892032
-
Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant
-
Kesari S, Randazzo BP, Valyi-Nagy T, et al. Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant. Lab Inves 1995;73:636e48.
-
(1995)
Lab Inves
, vol.73
-
-
Kesari, S.1
Randazzo, B.P.2
Valyi-Nagy, T.3
-
26
-
-
12944272092
-
Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma
-
Rampling R, Cruickshank G, Papanastassiou V, et al. Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma. Gene Ther 2000;7:859e66.
-
(2000)
Gene Ther
, vol.7
-
-
Rampling, R.1
Cruickshank, G.2
Papanastassiou, V.3
-
27
-
-
33749246871
-
Combined treatment of pediatric high-grade glioma with the oncolytic viral strain MTH-68/H and orl valpoic acid
-
Wagner S, Csatary CM, Gosztonyi G, et al. Combined treatment of pediatric high-grade glioma with the oncolytic viral strain MTH-68/H and orl valpoic acid. APMIS 2006;114:731e43.
-
(2006)
APMIS
, vol.114
-
-
Wagner, S.1
Csatary, C.M.2
Gosztonyi, G.3
-
28
-
-
0033526315
-
Use of Newcastle disease virus vaccine (MTH-68/H) in a patient with high-grade glioblastoma
-
Csatary LK, Bakacs T. Use of Newcastle disease virus vaccine (MTH-68/H) in a patient with high-grade glioblastoma. JAMA 1999;281:1588e9.
-
(1999)
JAMA
, vol.281
-
-
Csatary, L.K.1
Bakacs, T.2
-
29
-
-
1842484851
-
MTH-68/H oncolytic viral treatment in human high-grade gliomas
-
Csatary LK, Gosztonyi G, Szeberenyi J, et al. MTH-68/H oncolytic viral treatment in human high-grade gliomas. J Neurooncol 2004;67:83e93.
-
(2004)
J Neurooncol
, vol.67
-
-
Csatary, L.K.1
Gosztonyi, G.2
Szeberenyi, J.3
-
30
-
-
28844468988
-
Phase I/II trial of intravenous NDV-HUJ oncolytic virus in recurrent glioblastoma multiforme
-
Freeman AI, Zakay-Rones Z, Gomori JM, et al. Phase I/II trial of intravenous NDV-HUJ oncolytic virus in recurrent glioblastoma multiforme. Mol Ther 2006;13:221e8.
-
(2006)
Mol Ther
, vol.13
-
-
Freeman, A.I.1
Zakay-Rones, Z.2
Gomori, J.M.3
-
31
-
-
39849099798
-
A phase I trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas
-
Forsyth P, Roldan G, George D, et al. A phase I trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas. Mol Ther 2008;16:627e32.
-
(2008)
Mol Ther
, vol.16
-
-
Forsyth, P.1
Roldan, G.2
George, D.3
-
32
-
-
7044228126
-
A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting
-
Chiocca EA, Abbed KM, Tatter S, et al. A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. Mol Ther 2004;10:958e66.
-
(2004)
Mol Ther
, vol.10
-
-
Chiocca, E.A.1
Abbed, K.M.2
Tatter, S.3
-
33
-
-
79952200550
-
Gene therapy and virotherapy: Novel therapeutic approaches for brain tumors
-
Kroeger KM, Muhammad AK, Baker GJ, et al. Gene therapy and virotherapy: novel therapeutic approaches for brain tumors. Discov Med 2010;10:293e304.
-
(2010)
Discov Med
, vol.10
-
-
Kroeger, K.M.1
Muhammad, A.K.2
Baker, G.J.3
-
36
-
-
77249122967
-
HSV-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells
-
Matuskova M, Hlubinova K, Pastorakova A, et al. HSV-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells. Cancer Lett 2010;290:58e67.
-
(2010)
Cancer Lett
, vol.290
-
-
Matuskova, M.1
Hlubinova, K.2
Pastorakova, A.3
-
37
-
-
0028856844
-
Effect of herpes simplex virus thymidine kinase expression levels on ganciclovir-mediated cytotoxicity and the "Bystander effect"
-
Chen CY, Chang YN, Ryan P, et al. Effect of herpes simplex virus thymidine kinase expression levels on ganciclovir-mediated cytotoxicity and the "bystander effect". Hum Gene Ther 1995;6:1467e76.
-
(1995)
Hum Gene Ther
, vol.6
-
-
Chen, C.Y.1
Chang, Y.N.2
Ryan, P.3
-
38
-
-
19444369992
-
Neurosurgical delivery of chemotherapeutics, targeted toxins, genetic and viral therapies in neuro-oncology
-
Chiocca EA, Broaddus WC, Gillies GT, et al. Neurosurgical delivery of chemotherapeutics, targeted toxins, genetic and viral therapies in neuro-oncology. J Neurooncol 2004;69:101e17.
-
(2004)
J Neurooncol
, vol.69
-
-
Chiocca, E.A.1
Broaddus, W.C.2
Gillies, G.T.3
-
39
-
-
0034810796
-
Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma
-
Rainov NG, Fels C, Droege JW, et al. Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma. Cancer Gene Ther 2001;8:662e8.
-
(2001)
Cancer Gene Ther
, vol.8
-
-
Rainov, N.G.1
Fels, C.2
Droege, J.W.3
-
40
-
-
80053061789
-
Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma
-
Chiocca EA, Aguilar LK, Bell SD, et al. Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma. J Clin Oncol 2011;29:3611e19.
-
(2011)
J Clin Oncol
, vol.29
-
-
Chiocca, E.A.1
Aguilar, L.K.2
Bell, S.D.3
-
41
-
-
33747854225
-
The role of a HSV thymidine kinase stimulating substance, scopadulciol, in improving the efficacy of cancer gene therapy
-
Hayashi K, Lee JB, Maitani Y, et al. The role of a HSV thymidine kinase stimulating substance, scopadulciol, in improving the efficacy of cancer gene therapy. J Gene Med 2006;8:1056e67.
-
(2006)
J Gene Med
, vol.8
-
-
Hayashi, K.1
Lee, J.B.2
Maitani, Y.3
-
42
-
-
0036468901
-
Intratumoral 5-fluorouracil produced by cytosine deaminase/5- fluorocytosine gene therapy is effective for experimental human glioblastomas
-
Miller CR, Williams CR, Buchsbaum DJ, et al. Intratumoral 5-fluorouracil produced by cytosine deaminase/5-fluorocytosine gene therapy is effective for experimental human glioblastomas. Cancer Res 2002;62:773e80.
-
(2002)
Cancer Res
, vol.62
-
-
Miller, C.R.1
Williams, C.R.2
Buchsbaum, D.J.3
-
43
-
-
33748071125
-
Cytochrome P450 reductase dependent inhibition of cytochrome P450 2B1 activity: Implications for gene directed enzyme prodrug therapy
-
Lengler J, Omann M, Duvier D, et al. Cytochrome P450 reductase dependent inhibition of cytochrome P450 2B1 activity: implications for gene directed enzyme prodrug therapy. Biochem Pharmacol 2006;72:893e901.
-
(2006)
Biochem Pharmacol
, vol.72
-
-
Lengler, J.1
Omann, M.2
Duvier, D.3
-
44
-
-
0028800141
-
Enzyme/prodrug gene therapy: Comparison of cytosine deaminase/5- fluorocytosine versus thymidine kinase/ganciclovir enzyme/prodrug systems in a human colorectal carcinoma cell line
-
Trinh QT, Austin EA, Murray DM, et al. Enzyme/prodrug gene therapy: comparison of cytosine deaminase/5-fluorocytosine versus thymidine kinase/ganciclovir enzyme/prodrug systems in a human colorectal carcinoma cell line. Cancer Res 1995;55:4808e12.
-
(1995)
Cancer Res
, vol.55
-
-
Trinh, Q.T.1
Austin, E.A.2
Murray, D.M.3
-
45
-
-
84857569415
-
Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector
-
Ostertag D, Amundson KK, Lopez Espinoza F, et al. Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector. Neuro Oncol 2012;14:145e59.
-
(2012)
Neuro Oncol
, vol.14
-
-
Ostertag, D.1
Amundson, K.K.2
Lopez Espinoza, F.3
-
46
-
-
0036789520
-
Combined radiation and gene therapy for brain tumors with adenovirus-mediated transfer of cytosine deaminase and uracil phosphoribosyltransferase genes
-
Kambara H, Tamiya T, Ono Y, et al. Combined radiation and gene therapy for brain tumors with adenovirus-mediated transfer of cytosine deaminase and uracil phosphoribosyltransferase genes. Cancer Gene Ther 2002;9:840e5.
-
(2002)
Cancer Gene Ther
, vol.9
-
-
Kambara, H.1
Tamiya, T.2
Ono, Y.3
-
47
-
-
0032481577
-
Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies
-
Aghi M, Kramm CM, Chou TC, et al. Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. J Natl Cancer Inst 1998;90:370e80.
-
(1998)
J Natl Cancer Inst
, vol.90
-
-
Aghi, M.1
Kramm, C.M.2
Chou, T.C.3
-
48
-
-
0034493243
-
Combined antitumor effects of an adenoviral cytosine deaminase/thymidine kinase fusion gene in rat C6 glioma
-
Chang JW, Lee H, Kim E, et al. Combined antitumor effects of an adenoviral cytosine deaminase/thymidine kinase fusion gene in rat C6 glioma. Neurosurgery 2000;47:931e8.
-
(2000)
Neurosurgery
, vol.47
-
-
Chang, J.W.1
Lee, H.2
Kim, E.3
-
49
-
-
0034691208
-
Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: Toward realistic long-term neurological gene therapy for chronic diseases
-
Thomas CE, Schiedner G, Kochanek S, et al. Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for chronic diseases. Proc Natl Acad Sci United States America 2000;97:7482e7.
-
(2000)
Proc Natl Acad Sci United States America
, vol.97
-
-
Thomas, C.E.1
Schiedner, G.2
Kochanek, S.3
-
50
-
-
27944433469
-
Oncolytic viral therapies - The clinical experience
-
Aghi M, Martuza RL. Oncolytic viral therapies - the clinical experience. Oncogene 2005;24:7802e16.
-
(2005)
Oncogene
, vol.24
-
-
Aghi, M.1
Martuza, R.L.2
-
51
-
-
27144449641
-
Viral vectors as therapeutic agents for glioblastoma
-
Aghi M, Rabkin S. Viral vectors as therapeutic agents for glioblastoma. Curr Opinion Mol Ther 2005;7:419e30.
-
(2005)
Curr Opinion Mol Ther
, vol.7
-
-
Aghi, M.1
Rabkin, S.2
-
52
-
-
84861373232
-
Effect of gamma 34.5 deletions on oncolytic herpes simplex virus activity in brain tumors
-
Kanai R, Zaupa C, Sgubin D, et al. Effect of gamma 34.5 deletions on oncolytic herpes simplex virus activity in brain tumors. J Virol 2012;86:4420e31.
-
(2012)
J Virol
, vol.86
-
-
Kanai, R.1
Zaupa, C.2
Sgubin, D.3
-
53
-
-
85056026229
-
Herpesvirus vectors for therapy of brain tumors
-
Cassady KA, Parker JN. Herpesvirus vectors for therapy of brain tumors. Open Virol J 2010;4:103e8.
-
(2010)
Open Virol J
, vol.4
-
-
Cassady, K.A.1
Parker, J.N.2
-
54
-
-
0035933088
-
Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing
-
Todo T, Martuza RL, Rabkin SD, et al. Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing. Proc Natl Acad Sci USA 2001;98:6396e401.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
-
-
Todo, T.1
Martuza, R.L.2
Rabkin, S.D.3
-
55
-
-
37749001534
-
Co-option of signaling mechanisms from neural induction to telencephalic patterning
-
Aboitiz F, Montiel J. Co-option of signaling mechanisms from neural induction to telencephalic patterning. Rev Neurosci 2007;18:311e42.
-
(2007)
Rev Neurosci
, vol.18
-
-
Aboitiz, F.1
Montiel, J.2
-
56
-
-
33846421025
-
Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma
-
Danks MK, Yoon KJ, Bush RA, et al. Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma. Cancer Res 2007;67:22e5.
-
(2007)
Cancer Res
, vol.67
-
-
Danks, M.K.1
Yoon, K.J.2
Bush, R.A.3
-
57
-
-
31544468273
-
Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models
-
Terada K, Wakimoto H, Tyminski E, et al. Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models. Gene Ther 2006;13:705e14.
-
(2006)
Gene Ther
, vol.13
-
-
Terada, K.1
Wakimoto, H.2
Tyminski, E.3
-
58
-
-
33947375243
-
Development of a second-generation oncolytic herpes simplex virus expressing TNFalpha for cancer therapy
-
Han ZQ, Assenberg M, Liu BL, et al. Development of a second-generation oncolytic herpes simplex virus expressing TNFalpha for cancer therapy. J Gene Med 2007;9:99e106.
-
(2007)
J Gene Med
, vol.9
-
-
Han, Z.Q.1
Assenberg, M.2
Liu, B.L.3
-
59
-
-
84860542782
-
Replication-competent herpes simplex virus retargeted to HER2 as therapy for high-grade glioma
-
Gambini E, Reisoli E, Appolloni I, et al. Replication-competent herpes simplex virus retargeted to HER2 as therapy for high-grade glioma. Mol Ther 2012;20:994e1001.
-
(2012)
Mol Ther
, vol.20
-
-
Gambini, E.1
Reisoli, E.2
Appolloni, I.3
-
60
-
-
78751631362
-
Development of an oncolytic herpes simplex virus using a tumor-specific HIF-responsive promoter
-
Longo SL, Griffith C, Glass A, et al. Development of an oncolytic herpes simplex virus using a tumor-specific HIF-responsive promoter. Cancer Gene Ther 2011;18:123e34.
-
(2011)
Cancer Gene Ther
, vol.18
-
-
Longo, S.L.1
Griffith, C.2
Glass, A.3
-
61
-
-
78751649494
-
Cancer stem cells: The final frontier for glioma virotherapy
-
Dey M, Ulasov IV, Tyler MA, et al. Cancer stem cells: the final frontier for glioma virotherapy. Stem Cell Rev 2011;7:119e29.
-
(2011)
Stem Cell Rev
, vol.7
-
-
Dey, M.1
Ulasov, I.V.2
Tyler, M.A.3
-
62
-
-
34547523121
-
Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma
-
Ulasov IV, Zhu ZB, Tyler MA, et al. Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma. Hum Gene Ther 2007;18:589e602.
-
(2007)
Hum Gene Ther
, vol.18
-
-
Ulasov, I.V.1
Zhu, Z.B.2
Tyler, M.A.3
-
63
-
-
80053480063
-
A comparative study of neural and mesenchymal stem cell-based carriers for oncolytic adenovirus in a model of malignant glioma
-
Ahmed AU, Tyler MA, Thaci B, et al. A comparative study of neural and mesenchymal stem cell-based carriers for oncolytic adenovirus in a model of malignant glioma. Mol Pharm 2011;8:1559e72.
-
(2011)
Mol Pharm
, vol.8
-
-
Ahmed, A.U.1
Tyler, M.A.2
Thaci, B.3
-
64
-
-
80052406372
-
Neural stem cell-based cell carriers enhance therapeutic efficacy of an oncolytic adenovirus in an orthotopic mouse model of human glioblastoma
-
Ahmed AU, Thaci B, Alexiades NG, et al. Neural stem cell-based cell carriers enhance therapeutic efficacy of an oncolytic adenovirus in an orthotopic mouse model of human glioblastoma. Mol Ther 2011;19:1714e26.
-
(2011)
Mol Ther
, vol.19
-
-
Ahmed, A.U.1
Thaci, B.2
Alexiades, N.G.3
-
65
-
-
0032515141
-
Reovirus therapy of tumors with activated Ras pathway
-
Coffey MC, Strong JE, Forsyth PA, et al. Reovirus therapy of tumors with activated Ras pathway. Science 1998;282:1332e4.
-
(1998)
Science
, vol.282
-
-
Coffey, M.C.1
Strong, J.E.2
Forsyth, P.A.3
-
66
-
-
79952404748
-
Translational research in oncolytic measles virotherapy: Early discoveries and future steps
-
Msaouel P, Opyrchal M, Galanis E. Translational research in oncolytic measles virotherapy: early discoveries and future steps. Future Microbiol 2011;6:125e8.
-
(2011)
Future Microbiol
, vol.6
-
-
Msaouel, P.1
Opyrchal, M.2
Galanis, E.3
-
67
-
-
47549098591
-
Toxicology study of repeat intracerebral administration of a measles virus derivative producing carcinoembryonic antigen in rhesus macaques in support of a phase I/II clinical trial for patients with recurrent gliomas
-
Myers R, Harvey M, Kaufmann TJ, et al. Toxicology study of repeat intracerebral administration of a measles virus derivative producing carcinoembryonic antigen in rhesus macaques in support of a phase I/II clinical trial for patients with recurrent gliomas. Hum Gene Ther 2008;19:690e8.
-
(2008)
Hum Gene Ther
, vol.19
-
-
Myers, R.1
Harvey, M.2
Kaufmann, T.J.3
-
68
-
-
0036152214
-
Immunology of viral-vector-mediated gene transfer into the brain: An evolutionary and developmental perspective
-
Lowenstein PR. Immunology of viral-vector-mediated gene transfer into the brain: an evolutionary and developmental perspective. Trends Immunol 2002;23:23e30.
-
(2002)
Trends Immunol
, vol.23
-
-
Lowenstein, P.R.1
-
69
-
-
0033926042
-
Second-generation interferons for cancer: Clinical targets
-
Borden EC, Lindner D, Dreicer R, et al. Second-generation interferons for cancer: clinical targets. Semin Cancer Biol 2000;10:125e44.
-
(2000)
Semin Cancer Biol
, vol.10
-
-
Borden, E.C.1
Lindner, D.2
Dreicer, R.3
-
70
-
-
0027483695
-
The "Bystander effect": Tumor regression when a fraction of the tumor mass is genetically modified
-
Freeman SM, Abboud CN, Whartenby KA, et al. The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 1993;53:5274e83.
-
(1993)
Cancer Res
, vol.53
-
-
Freeman, S.M.1
Abboud, C.N.2
Whartenby, K.A.3
-
71
-
-
84861313680
-
Preclinical evaluation of a genetically engineered herpes simplex virus expressing Il-12
-
Markert JM, Cody JJ, Parker JN, et al. Preclinical evaluation of a genetically engineered herpes simplex virus expressing Il-12. J Virol 2012;86:5304e13.
-
(2012)
J Virol
, vol.86
-
-
Markert, J.M.1
Cody, J.J.2
Parker, J.N.3
-
72
-
-
79955034826
-
Gene therapy of intracranial glioma using interleukin 12-secreting human umbilical cord blood-derived mesenchymal stem cells
-
Ryu CH, Park SH, Park SA, et al. Gene therapy of intracranial glioma using interleukin 12-secreting human umbilical cord blood-derived mesenchymal stem cells. Hum Gene Ther 2011;22:733e43.
-
(2011)
Hum Gene Ther
, vol.22
-
-
Ryu, C.H.1
Park, S.H.2
Park, S.A.3
-
73
-
-
78650537312
-
Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics
-
Candolfi M, Xiong W, Yagiz K, et al. Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics. Proc Natl Acad Sci USA 2010;107:20021e6.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
-
-
Candolfi, M.1
Xiong, W.2
Yagiz, K.3
-
74
-
-
80052291361
-
Continuous local delivery of interferon-beta stabilizes tumor vasculature in an orthotopic glioblastoma xenograft resection model
-
Denbo JW, Williams RF, Orr WS, et al. Continuous local delivery of interferon-beta stabilizes tumor vasculature in an orthotopic glioblastoma xenograft resection model. Surgery 2011;150:497e504.
-
(2011)
Surgery
, vol.150
-
-
Denbo, J.W.1
Williams, R.F.2
Orr, W.S.3
-
75
-
-
79960116603
-
Interferon: Current status and future prospects in cancer therapy
-
Wang BX, Rahbar R, Fish EN. Interferon: current status and future prospects in cancer therapy. J Interferon Cytokine Res 2011;31:545e52.
-
(2011)
J Interferon Cytokine Res
, vol.31
-
-
Wang, B.X.1
Rahbar, R.2
Fish, E.N.3
-
76
-
-
42049112450
-
A phase I clinical trial of interferon-beta gene therapy for high-grade glioma: Novel findings from gene expression profiling and autopsy
-
Wakabayashi T, Natsume A, Hashizume Y, et al. A phase I clinical trial of interferon-beta gene therapy for high-grade glioma: novel findings from gene expression profiling and autopsy. J Gene Med 2008;10:329e39.
-
(2008)
J Gene Med
, vol.10
-
-
Wakabayashi, T.1
Natsume, A.2
Hashizume, Y.3
-
77
-
-
39849092406
-
A phase I trial of Ad.hIFN-beta gene therapy for glioma
-
Chiocca EA, Smith KM, McKinney B, et al. A phase I trial of Ad.hIFN-beta gene therapy for glioma. Mol Ther 2008;16:618e26.
-
(2008)
Mol Ther
, vol.16
-
-
Chiocca, E.A.1
Smith, K.M.2
McKinney, B.3
-
78
-
-
70349982431
-
HMGB1 mediates endogenous TLR2 activation and brain tumor regression
-
Curtin JF, Liu N, Candolfi M, et al. HMGB1 mediates endogenous TLR2 activation and brain tumor regression. PloS Med 2009;6:e10.
-
(2009)
PloS Med
, vol.6
-
-
Curtin, J.F.1
Liu, N.2
Candolfi, M.3
-
79
-
-
67650360785
-
Release of HMGB1 in response to proapoptotic glioma killing strategies: Efficacy and neurotoxicity
-
Candolfi M, Yagiz K, Foulad D, et al. Release of HMGB1 in response to proapoptotic glioma killing strategies: efficacy and neurotoxicity. Clin Cancer Res 2009;15:4401e14.
-
(2009)
Clin Cancer Res
, vol.15
-
-
Candolfi, M.1
Yagiz, K.2
Foulad, D.3
-
80
-
-
77955924466
-
Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas
-
Germano IM, Emdad L, Qadeer ZA, et al. Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas. Cancer Gene Ther 2010;17:664e74.
-
(2010)
Cancer Gene Ther
, vol.17
-
-
Germano, I.M.1
Emdad, L.2
Qadeer, Z.A.3
-
81
-
-
34047215877
-
Enhanced proapoptotic effects of tumor necrosis factor-related apoptosis-inducing ligand on temozolomide-resistant glioma cells
-
Uzzaman M, Keller G, Germano IM. Enhanced proapoptotic effects of tumor necrosis factor-related apoptosis-inducing ligand on temozolomide-resistant glioma cells. J Neurosurg 2007;106:646e51.
-
(2007)
J Neurosurg
, vol.106
-
-
Uzzaman, M.1
Keller, G.2
Germano, I.M.3
-
83
-
-
77957375466
-
Mesenchymal stem cells modified with a single-chain antibody against EGFRvIII successfully inhibit the growth of human xenograft malignant glioma
-
Balyasnikova IV, Ferguson SD, Sengupta S, et al. Mesenchymal stem cells modified with a single-chain antibody against EGFRvIII successfully inhibit the growth of human xenograft malignant glioma. Plos One 2010;5:e9750.
-
(2010)
Plos One
, vol.5
-
-
Balyasnikova, I.V.1
Ferguson, S.D.2
Sengupta, S.3
-
84
-
-
32444450342
-
Gene therapy progress and prospects: Magnetic nanoparticle-based gene delivery
-
Dobson J. Gene therapy progress and prospects: magnetic nanoparticle-based gene delivery. Gene Ther 2006;13:283e7.
-
(2006)
Gene Ther
, vol.13
-
-
Dobson, J.1
-
85
-
-
33847155509
-
Nanoparticle-mediated drug delivery and gene therapy
-
Jin S, Ye K. Nanoparticle-mediated drug delivery and gene therapy. Biotechnol Prog 2007;23:32e41.
-
(2007)
Biotechnol Prog
, vol.23
-
-
Jin, S.1
Ye, K.2
-
86
-
-
65649101289
-
Gene therapy as an adjuvant treatment for malignant gliomas: From bench to bedside
-
Germano IM, Binello E. Gene therapy as an adjuvant treatment for malignant gliomas: from bench to bedside. J Neurooncol 2009;93:79e87.
-
(2009)
J Neurooncol
, vol.93
-
-
Germano, I.M.1
Binello, E.2
-
87
-
-
84555220669
-
In vivo specific delivery of c-Met siRNA to glioblastoma using cationic solid lipid nanoparticles
-
Jin J, Bae KH, Yang H, et al. In vivo specific delivery of c-Met siRNA to glioblastoma using cationic solid lipid nanoparticles. Bioconjugate Chem 2011;22:2568e72.
-
(2011)
Bioconjugate Chem
, vol.22
-
-
Jin, J.1
Bae, K.H.2
Yang, H.3
-
88
-
-
39549117983
-
Delivery vehicles for small interfering RNA in vivo
-
de Fougerolles AR. Delivery vehicles for small interfering RNA in vivo. Hum Gene Ther 2008;19:125e32.
-
(2008)
Hum Gene Ther
, vol.19
-
-
De Fougerolles, A.R.1
-
89
-
-
0034619328
-
Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracranial gliomas
-
Aboody KS, Brown A, Rainov NG, et al. Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci USA 2000;97:12846e51.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
-
-
Aboody, K.S.1
Brown, A.2
Rainov, N.G.3
-
90
-
-
33846443750
-
Development of a tumor-selective approach to treat metastatic cancer
-
Aboody KS, Bush RA, Garcia E, et al. Development of a tumor-selective approach to treat metastatic cancer. Plos One 2006;1:e23.
-
(2006)
Plos One
, vol.1
-
-
Aboody, K.S.1
Bush, R.A.2
Garcia, E.3
-
91
-
-
84859376209
-
Phase I/II trial of carboplatin and paclitaxel chemotherapy in combination with intravenous oncolytic reovirus in patients with advanced malignancies
-
Karapanagiotou E, Roulstone V, Twigger K, et al. Phase I/II trial of carboplatin and paclitaxel chemotherapy in combination with intravenous oncolytic reovirus in patients with advanced malignancies. Clin Cancer Res 2012;18:2080e9.
-
(2012)
Clin Cancer Res
, vol.18
-
-
Karapanagiotou, E.1
Roulstone, V.2
Twigger, K.3
-
92
-
-
33846188096
-
Cationic albumin-conjugated pegylated nanoparticles allow gene delivery into brain tumors via intravenous administration
-
Lu W, Sun Q, Wan J, et al. Cationic albumin-conjugated pegylated nanoparticles allow gene delivery into brain tumors via intravenous administration. Cancer Res 2006;66:11878e87.
-
(2006)
Cancer Res
, vol.66
-
-
Lu, W.1
Sun, Q.2
Wan, J.3
-
93
-
-
79954902379
-
Evaluation and optimization of the administration of a selectively replicating herpes simplex viral vector to the brain by convection-enhanced delivery
-
White E, Bienemann A, Megraw L, et al. Evaluation and optimization of the administration of a selectively replicating herpes simplex viral vector to the brain by convection-enhanced delivery. Cancer Gene Ther 2011;18:358e69.
-
(2011)
Cancer Gene Ther
, vol.18
-
-
White, E.1
Bienemann, A.2
Megraw, L.3
-
94
-
-
22444450988
-
Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism
-
Pluchino S, Zanotti L, Rossi B, et al. Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism. Nature 2005;436:266e71.
-
(2005)
Nature
, vol.436
-
-
Pluchino, S.1
Zanotti, L.2
Rossi, B.3
-
95
-
-
0035448565
-
Positron-emission tomography of vector-mediated gene expression in gene therapy for gliomas
-
Jacobs A, Voges J, Reszka R, et al. Positron-emission tomography of vector-mediated gene expression in gene therapy for gliomas. Lancet 2001;358:727e9.
-
(2001)
Lancet
, vol.358
-
-
Jacobs, A.1
Voges, J.2
Reszka, R.3
-
96
-
-
67649961354
-
Identification of cancer stem cells in dog glioblastoma
-
Stoica G, Lungu G, Martini-Stoica H, et al. Identification of cancer stem cells in dog glioblastoma. Vet Pathol 2009;46:391e406.
-
(2009)
Vet Pathol
, vol.46
-
-
Stoica, G.1
Lungu, G.2
Martini-Stoica, H.3
-
97
-
-
0019048265
-
Reversible osmotic blood-brain barrier disruption in humans: Implications for the chemotherapy of malignant brain tumors
-
Neuwelt EA. Reversible osmotic blood-brain barrier disruption in humans: implications for the chemotherapy of malignant brain tumors. Neurosurgery 1980;7:204.
-
(1980)
Neurosurgery
, vol.7
, pp. 204
-
-
Neuwelt, E.A.1
-
98
-
-
17444427673
-
Differential susceptibility of primary and established human glioma cells to adenovirus infection: Targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer
-
Miller CR, Buchsbaum DJ, Reynolds PN, et al. Differential susceptibility of primary and established human glioma cells to adenovirus infection: targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer. Cancer Res 1998;58:5738e48.
-
(1998)
Cancer Res
, vol.58
-
-
Miller, C.R.1
Buchsbaum, D.J.2
Reynolds, P.N.3
-
99
-
-
23444437213
-
Convection-enhanced delivery of macromolecules in the brain
-
Bobo RH, Laske DW, Akbasak A, et al. Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci USA 1994;91:2076e80.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
-
-
Bobo, R.H.1
Laske, D.W.2
Akbasak, A.3
-
100
-
-
23044462079
-
Convection-enhanced drug delivery: Increased efficacy and magnetic resonance image monitoring
-
Mardor Y, Rahav O, Zauberman Y, et al. Convection-enhanced drug delivery: increased efficacy and magnetic resonance image monitoring. Cancer Res 2005;65:6858e63.
-
(2005)
Cancer Res
, vol.65
-
-
Mardor, Y.1
Rahav, O.2
Zauberman, Y.3
-
101
-
-
0031451777
-
Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors
-
Laske DW, Youle RJ, Oldfield EH. Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors. Nat Med 1997;3:1362e8.
-
(1997)
Nat Med
, vol.3
-
-
Laske, D.W.1
Youle, R.J.2
Oldfield, E.H.3
-
102
-
-
22044450632
-
AAV2-mediated gene delivery to monkey putamen: Evaluation of an infusion device and delivery parameters
-
Sanftner LM, Sommer JM, Suzuki BM, et al. AAV2-mediated gene delivery to monkey putamen: evaluation of an infusion device and delivery parameters. Exp Neurol 2005;194:476e83.
-
(2005)
Exp Neurol
, vol.194
-
-
Sanftner, L.M.1
Sommer, J.M.2
Suzuki, B.M.3
-
103
-
-
0034117480
-
Gene therapy of experimental brain tumors using neural progenitor cells
-
Benedetti S, Pirola B, Pollo B, et al. Gene therapy of experimental brain tumors using neural progenitor cells. Nat Med 2000;6:447e50.
-
(2000)
Nat Med
, vol.6
-
-
Benedetti, S.1
Pirola, B.2
Pollo, B.3
-
104
-
-
0029004025
-
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
Dvorak HF, Brown LF, Detmar M, et al. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995;146:1029e39.
-
(1995)
Am J Pathol
, vol.146
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
-
105
-
-
77957606508
-
Bone marrow mesenchymal stem cells loaded with an oncolytic adenovirus Suppress the anti-adenoviral immune response in the cotton rat model
-
Ahmed AU, Rolle CE, Tyler MA, et al. Bone marrow mesenchymal stem cells loaded with an oncolytic adenovirus Suppress the anti-adenoviral immune response in the cotton rat model. Mol Ther 2010;18:1846e56.
-
(2010)
Mol Ther
, vol.18
-
-
Ahmed, A.U.1
Rolle, C.E.2
Tyler, M.A.3
-
106
-
-
42249086829
-
The changing face of neural stem cell therapy in neurologic diseases
-
Einstein O, Ben-Hur T. The changing face of neural stem cell therapy in neurologic diseases. Arch Neurol 2008;65:452e6.
-
(2008)
Arch Neurol
, vol.65
-
-
Einstein, O.1
Ben-Hur, T.2
-
107
-
-
77952555038
-
Exciting new advances in neuro-oncology: The avenue to a cure for malignant glioma
-
Van Meir EG, Hadjipanayis CG, Norden AD, et al. Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA Cancer J Clin 2010;60:166e93.
-
(2010)
CA Cancer J Clin
, vol.60
-
-
Van Meir, E.G.1
Hadjipanayis, C.G.2
Norden, A.D.3
-
108
-
-
84856957895
-
Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma
-
Zhang W, Fulci G, Buhrman JS, et al. Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma. Mol Ther 2012;20:37e45.
-
(2012)
Mol Ther
, vol.20
-
-
Zhang, W.1
Fulci, G.2
Buhrman, J.S.3
-
109
-
-
77951987824
-
Synergistic interaction between oncolytic viruses augments tumor killing
-
Le Boeuf F, Diallo JS, McCart JA, et al. Synergistic interaction between oncolytic viruses augments tumor killing. Mol Ther 2010;18:888e95.
-
(2010)
Mol Ther
, vol.18
-
-
Le Boeuf, F.1
Diallo, J.S.2
McCart, J.A.3
-
111
-
-
48649086074
-
Tissue-specific promoters active in CD44+CD24-/low breast cancer cells
-
Bauerschmitz GJ, Ranki T, Kangasniemi L, et al. Tissue-specific promoters active in CD44+CD24-/low breast cancer cells. Cancer Res 2008;68:5533e9.
-
(2008)
Cancer Res
, vol.68
-
-
Bauerschmitz, G.J.1
Ranki, T.2
Kangasniemi, L.3
-
112
-
-
80555127418
-
Targeting brain tumor stem cells with oncolytic adenoviruses
-
Alonso MM, Jiang H, Gomez-Manzano C, et al. Targeting brain tumor stem cells with oncolytic adenoviruses. Methods Mol Biol 2012;797:111e25.
-
(2012)
Methods Mol Biol
, vol.797
-
-
Alonso, M.M.1
Jiang, H.2
Gomez-Manzano, C.3
-
113
-
-
82555189374
-
Enhanced antitumor efficacy of low-dose etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts
-
Cheema TA, Kanai R, Kim GW, et al. Enhanced antitumor efficacy of low-dose etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts. Clin Cancer Res 2011;17:7383e93.
-
(2011)
Clin Cancer Res
, vol.17
-
-
Cheema, T.A.1
Kanai, R.2
Kim, G.W.3
-
114
-
-
84855486345
-
Oncolytic virus-mediated manipulation of DNA damage responses: Synergy with chemotherapy in killing glioblastoma stem cells
-
Kanai R, Rabkin SD, Yip S, et al. Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells. J Natl Cancer Inst 2012;104:42e55.
-
(2012)
J Natl Cancer Inst
, vol.104
-
-
Kanai, R.1
Rabkin, S.D.2
Yip, S.3
-
115
-
-
79957881687
-
A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells
-
Kanai R, Wakimoto H, Martuza RL, et al. A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells. Clin Cancer Res 2011;17:3686e96.
-
(2011)
Clin Cancer Res
, vol.17
-
-
Kanai, R.1
Wakimoto, H.2
Martuza, R.L.3
-
116
-
-
79955634782
-
Glioma stem cells targeted by oncolytic virus carrying endostatin-angiostatin fusion gene and the expression of its exogenous gene in vitro
-
Zhu G, Su W, Jin G, et al. Glioma stem cells targeted by oncolytic virus carrying endostatin-angiostatin fusion gene and the expression of its exogenous gene in vitro. Brain Res 2011;1390:59e69.
-
(2011)
Brain Res
, vol.1390
-
-
Zhu, G.1
Su, W.2
Jin, G.3
-
117
-
-
77955653069
-
Side populations of glioblastoma cells are less sensitive to HSV-TK/GCV suicide gene therapy system than the non-side population
-
Hu WW, Liu WG. Side populations of glioblastoma cells are less sensitive to HSV-TK/GCV suicide gene therapy system than the non-side population. In Vitro Cell Dev Biol Anim 2010;46:497e501.
-
(2010)
In Vitro Cell Dev Biol Anim
, vol.46
-
-
Hu, W.W.1
Liu, W.G.2
-
118
-
-
22144476218
-
Applications of mouse glioma models in preclinical trials
-
Hu X, Holland EC. Applications of mouse glioma models in preclinical trials. Mutat Res 2005;576:54e65.
-
(2005)
Mutat Res
, vol.576
-
-
Hu, X.1
Holland, E.C.2
-
119
-
-
35449004503
-
Intracranial glioblastoma models in preclinical neuro-oncology: Neuropathological characterization and tumor progression
-
Candolfi M, Curtin JF, Nichols WS, et al. Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression. J Neurooncol 2007;85:133e48.
-
(2007)
J Neurooncol
, vol.85
-
-
Candolfi, M.1
Curtin, J.F.2
Nichols, W.S.3
-
120
-
-
73449115350
-
Uncertainty in the translation of preclinical experiments to clinical trials. Why do most phase III clinical trials fail?
-
Lowenstein PR, Castro MG. Uncertainty in the translation of preclinical experiments to clinical trials. Why do most phase III clinical trials fail? Curr Gene Ther 2009;9:368e74.
-
(2009)
Curr Gene Ther
, vol.9
-
-
Lowenstein, P.R.1
Castro, M.G.2
-
121
-
-
48649100068
-
Low-dose radiation enhances survivin-mediated virotherapy against malignant glioma stem cells
-
Nandi S, Ulasov IV, Tyler MA, et al. Low-dose radiation enhances survivin-mediated virotherapy against malignant glioma stem cells. Cancer Res 2008;68:5778e84.
-
(2008)
Cancer Res
, vol.68
-
-
Nandi, S.1
Ulasov, I.V.2
Tyler, M.A.3
|