Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas

Cancer Gene Therapy

Volumn 17, Issue 9, 2010, Pages 664-674

  Germano, I M ^a   Emdad, L ^a   Qadeer, Z A ^a   Binello, E ^a   Uzzaman, M ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

apoptosis; autophagy; Embryonic stem cell; gene delivery; malignant gliomas

Indexed keywords

TEMOZOLOMIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CANCER GENE THERAPY; CANCER GRADING; CANCER INHIBITION; CANCER PATIENT; CANCER RESISTANCE; CANCER SURVIVAL; CELL BASED GENE THERAPY; CONTROLLED STUDY; EMBRYONIC STEM CELL; GENE; GLIOBLASTOMA; HUMAN; HUMAN CELL; IL 24 GENE; IONIZING RADIATION; MDA 7 GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; RADIOSENSITIZATION; SIGNAL TRANSDUCTION; TRANSGENE; TREATMENT OUTCOME;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; APOPTOSIS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL PROLIFERATION; CELLS, CULTURED; COMBINED MODALITY THERAPY; DACARBAZINE; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, NEOPLASM; EMBRYONIC STEM CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GLIOMA; HUMANS; IMMUNOENZYME TECHNIQUES; INTERLEUKINS; MICE; MICE, NUDE; RADIATION, IONIZING; RADIATION-SENSITIZING AGENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSGENES; TUMOR STEM CELL ASSAY;

EID: 77955924466     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2010.31     Document Type: Article

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