-
1
-
-
0025233918
-
Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovius infection
-
Faulds D, Heel RC. Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovius infection. Drugs 1990; 39: 5997-6331.
-
(1990)
Drugs
, vol.39
, pp. 5997-6331
-
-
Faulds, D.1
Heel, R.C.2
-
2
-
-
0017639148
-
Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine
-
Elion GB, Furman PA, Fyfe JA, et al. Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine. Proc Natl Acad Sci U S A 1977; 74: 5716-5720.
-
(1977)
Proc Natl Acad Sci U S A
, vol.74
, pp. 5716-5720
-
-
Elion, G.B.1
Furman, P.A.2
Fyfe, J.A.3
-
3
-
-
0018251481
-
Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound 9-(2-hydroxyethoxymethyl) guanine
-
Fyfe JA, Keller PM, Furman PA, et al. Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound 9-(2-hydroxyethoxymethyl) guanine. J Biol Chem 1978; 253: 8721-8727.
-
(1978)
J Biol Chem
, vol.253
, pp. 8721-8727
-
-
Fyfe, J.A.1
Keller, P.M.2
Furman, P.A.3
-
4
-
-
0019906763
-
Mechanism of action and selectivity of acyclovir
-
Elion GB. Mechanism of action and selectivity of acyclovir. Am J Med 1982; 3: 7-13.
-
(1982)
Am J Med
, vol.3
, pp. 7-13
-
-
Elion, G.B.1
-
5
-
-
0019321437
-
Phosphorylation of acyclovir (acycloguanine) monophosphate by GMP kinase
-
Miller WH, Miller RL. Phosphorylation of acyclovir (acycloguanine) monophosphate by GMP kinase. J Biol Chem 1980; 255: 7204-7207.
-
(1980)
J Biol Chem
, vol.255
, pp. 7204-7207
-
-
Miller, W.H.1
Miller, R.L.2
-
6
-
-
0020408238
-
Phosphorylation of acyclovir diphosphate by cellular enzymes
-
Miller WH, Miller RL. Phosphorylation of acyclovir diphosphate by cellular enzymes. Biochem Pharmacol 1982; 31: 3879-3884.
-
(1982)
Biochem Pharmacol
, vol.31
, pp. 3879-3884
-
-
Miller, W.H.1
Miller, R.L.2
-
7
-
-
0020261015
-
Activation by thymidine kinase and potent antiherpetic activity of 2′-nor-2′-deoxyguanosine (2′-NDG)
-
Ashton WT, Karkas JD, Field AK, et al. Activation by thymidine kinase and potent antiherpetic activity of 2′-nor-2′-deoxyguanosine (2′-NDG). Biochem Biophys Res Commun 1982; 108: 1716-1721.
-
(1982)
Biochem Biophys Res Commun
, vol.108
, pp. 1716-1721
-
-
Ashton, W.T.1
Karkas, J.D.2
Field, A.K.3
-
8
-
-
0002391736
-
Unique spectrum of activity of 9-(1,3-dihydroxy-2-propoxymethyl)guanine against herpes viruses in vitro and its mode of action against herpes simplex virus type 1
-
Cheng YC, Huang ES, Lin JC, et al. Unique spectrum of activity of 9-(1,3-dihydroxy-2-propoxymethyl)guanine against herpes viruses in vitro and its mode of action against herpes simplex virus type 1. Proc Natl Acad Sci U S A 1983; 80: 2767-2770.
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 2767-2770
-
-
Cheng, Y.C.1
Huang, E.S.2
Lin, J.C.3
-
9
-
-
0021055765
-
Metabolism of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new antiherpes virus compound, in herpes simplex virus-infected cells
-
Cheng YC, Grill SP, Dutschman GE, et al. Metabolism of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new antiherpes virus compound, in herpes simplex virus-infected cells. J Biol Chem 1983; 258: 12460-12464.
-
(1983)
J Biol Chem
, vol.258
, pp. 12460-12464
-
-
Cheng, Y.C.1
Grill, S.P.2
Dutschman, G.E.3
-
10
-
-
0020262167
-
9-([2-Hydroxy-1-(hydroxymethyl)ethoxy]lmethylguanine: A selective inhibitor of herpes group virus replication
-
Field AK, Davies ME, Dewitt C, et al. 9-([2-Hydroxy-1-(hydroxymethyl)ethoxy]lmethylguanine: a selective inhibitor of herpes group virus replication. Proc Natl Acad Sci U S A 1983; 80: 4139-4143.
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 4139-4143
-
-
Field, A.K.1
Davies, M.E.2
Dewitt, C.3
-
11
-
-
0021860994
-
Intracellular metabolism and enzymatic phosphorylation of 9-(1,3-dihydroxy-2-propoxymethyl)guanine and acyclovir in herpes simplex virus-infected and uninfected cells
-
Smee DF, Boehme R, Chernow M, et al. Intracellular metabolism and enzymatic phosphorylation of 9-(1,3-dihydroxy-2-propoxymethyl)guanine and acyclovir in herpes simplex virus-infected and uninfected cells. Biochem Pharmacol 1985; 34: 1049-1056.
-
(1985)
Biochem Pharmacol
, vol.34
, pp. 1049-1056
-
-
Smee, D.F.1
Boehme, R.2
Chernow, M.3
-
12
-
-
0018733296
-
Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxymethyl)guanine and its triphosphate
-
Furman PA, St. Clair MH, Fyfe JA, et al. Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxymethyl)guanine and its triphosphate. J Virol 1979; 32: 72-77.
-
(1979)
J Virol
, vol.32
, pp. 72-77
-
-
Furman, P.A.1
St. Clair, M.H.2
Fyfe, J.A.3
-
13
-
-
0026772206
-
In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
-
Culver KW, Ram Z, Walbridge S, et al. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 1992; 256: 1550-1552.
-
(1992)
Science
, vol.256
, pp. 1550-1552
-
-
Culver, K.W.1
Ram, Z.2
Walbridge, S.3
-
14
-
-
0027291236
-
Regression of established macroscopic liver metastases after in situ transduction of a suicide gene
-
Caruso M, Panis Y, Gagandeep S, et al. Regression of established macroscopic liver metastases after in situ transduction of a suicide gene. Proc Natl Acad Sci U S A 1993; 90: 7024-7028.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 7024-7028
-
-
Caruso, M.1
Panis, Y.2
Gagandeep, S.3
-
15
-
-
0027548077
-
Gene therapy for the treatment of brain tumors using intratumoral transduction with the thymidine kinase gene and intravenous ganciclovir
-
Oldfield H, Ram Z, Culver KW, et al. Gene therapy for the treatment of brain tumors using intratumoral transduction with the thymidine kinase gene and intravenous ganciclovir. Hum Gene Ther 1993; 4: 39-69.
-
(1993)
Hum Gene Ther
, vol.4
, pp. 39-69
-
-
Oldfield, H.1
Ram, Z.2
Culver, K.W.3
-
16
-
-
0027531548
-
In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats
-
Ram Z, Culver WK, Walbridge S, et al. In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats. Cancer Res 1993; 53: 83-88.
-
(1993)
Cancer Res
, vol.53
, pp. 83-88
-
-
Ram, Z.1
Culver, W.K.2
Walbridge, S.3
-
17
-
-
0028202066
-
Gene therapy for brain tumors: Regression of experimental gliomas by adenovirus-mediated gene transfer in vivo
-
Chen SH, Shine HD, Goodman JC, et al. Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo. Proc Natl Acad Sci U S A 1994; 91: 3054-3057.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 3054-3057
-
-
Chen, S.H.1
Shine, H.D.2
Goodman, J.C.3
-
18
-
-
17344365922
-
Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: Results of a phase 1 clinical trial in malignant mesothelioma
-
Sterman DH, Treat J, Litzky LA, et al. Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase 1 clinical trial in malignant mesothelioma. Hum. Gene Ther 1998; 9: 1083-1092.
-
(1998)
Hum. Gene Ther
, vol.9
, pp. 1083-1092
-
-
Sterman, D.H.1
Treat, J.2
Litzky, L.A.3
-
19
-
-
0032809839
-
Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers
-
Clayman GL, Frank DK, Bruso PA, et al. Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers. Clin Cancer Res 1999; 5: 1715-1722.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1715-1722
-
-
Clayman, G.L.1
Frank, D.K.2
Bruso, P.A.3
-
20
-
-
0033135221
-
In situ gene therapy for adenocarcinoma of the prostate: A phase I clinical trial
-
Herman JR, Adler HL, Aguil-Cordova E, et al. In situ gene therapy for adenocarcinoma of the prostate: a phase I clinical trial. Hum Gene Ther 1999; 10: 1239-1249.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 1239-1249
-
-
Herman, J.R.1
Adler, H.L.2
Aguil-Cordova, E.3
-
21
-
-
0032971662
-
Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: Results of a phase I clinical trial
-
Stewart AK, Lassam NJ, Quirt IC, et al. Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase I clinical trial. Gene Ther 1999; 6: 350-363.
-
(1999)
Gene Ther
, vol.6
, pp. 350-363
-
-
Stewart, A.K.1
Lassam, N.J.2
Quirt, I.C.3
-
22
-
-
0033526357
-
Adenovirus-mediated p53 gene transfer in advanced non-small cell lung cancer
-
Swisher SG, Roth JA, Nemunaitis J, et al. Adenovirus-mediated p53 gene transfer in advanced non-small cell lung cancer. J Natl Cancer Inst 1999; 91: 763-771.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 763-771
-
-
Swisher, S.G.1
Roth, J.A.2
Nemunaitis, J.3
-
23
-
-
0022485359
-
Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
-
Moolten FL. Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res 1986; 46: 5276-5281.
-
(1986)
Cancer Res
, vol.46
, pp. 5276-5281
-
-
Moolten, F.L.1
-
24
-
-
0025241769
-
Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors
-
Moolten FL, Wells JM. Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors. J Natl Cancer Inst 1990; 82: 297-300.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 297-300
-
-
Moolten, F.L.1
Wells, J.M.2
-
25
-
-
0025899005
-
Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene
-
Ezzeddine ZD, Martuza RL, Platikai D, et al. Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene. New Biol 1991; 3: 608-614.
-
(1991)
New Biol
, vol.3
, pp. 608-614
-
-
Ezzeddine, Z.D.1
Martuza, R.L.2
Platikai, D.3
-
26
-
-
0027483695
-
The 'bystander effect': Tumor regression when a fraction of the tumor mass is genetically modified
-
Freeman SM, Abboud CN, Whartenby KA, et al. The 'bystander effect': tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 1993; 53: 5274-5283.
-
(1993)
Cancer Res
, vol.53
, pp. 5274-5283
-
-
Freeman, S.M.1
Abboud, C.N.2
Whartenby, K.A.3
-
27
-
-
0030742974
-
The role of the bystander effect in suicide gene therapy
-
Pope IM, Poston GJ, Kinsella AR. The role of the bystander effect in suicide gene therapy. Eur J Cancer 1997; 33: 1005-1016.
-
(1997)
Eur J Cancer
, vol.33
, pp. 1005-1016
-
-
Pope, I.M.1
Poston, G.J.2
Kinsella, A.R.3
-
28
-
-
0025931346
-
+-ATPase from Scoparia dulcis, and its structure-activity relationships
-
+-ATPase from Scoparia dulcis, and its structure-activity relationships. J Natl Prod 1991; 54: 802-809.
-
(1991)
J Natl Prod
, vol.54
, pp. 802-809
-
-
Hayashi, T.1
Asano, S.2
Mizutani, M.3
-
29
-
-
0029880199
-
Scopadulciol is an inhibitor of herpes simplex virus type 1 and a potentiator of acyclovir
-
Hayshi K, Hayashi T. Scopadulciol is an inhibitor of herpes simplex virus type 1 and a potentiator of acyclovir. Antiviral Chem Chemother 1996; 7: 79-85.
-
(1996)
Antiviral Chem Chemother
, vol.7
, pp. 79-85
-
-
Hayshi, K.1
Hayashi, T.2
-
30
-
-
0027480081
-
Differential mechanism of cytostatic effect of (E)-5-(2-bromovinyl)- 2′-deoxyuridine,9-(1,3-dihydroxy-2-propoxymethyl)guanine, and other antiherpetic drugs on tumor cells transfected by the thymidine kinase gene of herpes simplex virus type 1 or type 2
-
Balzarini J, Bohman C, DeClercq E. Differential mechanism of cytostatic effect of (E)-5-(2-bromovinyl) -2′-deoxyuridine,9-(1,3-dihydroxy-2-propoxymethyl)guanine, and other antiherpetic drugs on tumor cells transfected by the thymidine kinase gene of herpes simplex virus type 1 or type 2. J Biol Chem 1993; 268: 6332-6337.
-
(1993)
J Biol Chem
, vol.268
, pp. 6332-6337
-
-
Balzarini, J.1
Bohman, C.2
DeClercq, E.3
-
31
-
-
0031463632
-
Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
-
Ram Z, Culver KW, Oshiro EM, et al. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nat Med 1997; 3: 1354-1361.
-
(1997)
Nat Med
, vol.3
, pp. 1354-1361
-
-
Ram, Z.1
Culver, K.W.2
Oshiro, E.M.3
-
32
-
-
0023177097
-
Scopadulcic acid-A and -B, new diterpenoids with a novel skeleton, from a Paraguayan crude drug Typychá Kuratû (Scoparia dulcis L.)
-
Hayashi T, Kishi M, Kawasaki M, et al. Scopadulcic acid-A and -B, new diterpenoids with a novel skeleton, from a Paraguayan crude drug Typychá Kuratû (Scoparia dulcis L.). Tetrahedron Lett 1987; 28: 3693-3696.
-
(1987)
Tetrahedron Lett
, vol.28
, pp. 3693-3696
-
-
Hayashi, T.1
Kishi, M.2
Kawasaki, M.3
-
33
-
-
0014186966
-
A novel method for phosphorylation of nucleosides to 5′-nucleotides
-
Yoshikawa M, Kato T, Takenishi T. A novel method for phosphorylation of nucleosides to 5′-nucleotides. Tetrahedron Lett 1967; 50: 5065-5068.
-
(1967)
Tetrahedron Lett
, vol.50
, pp. 5065-5068
-
-
Yoshikawa, M.1
Kato, T.2
Takenishi, T.3
-
34
-
-
0033951472
-
Potentiation of ganciclovir toxicity in the herpes simplex virus thymidine kinase/ganciclovir administration system by ponicidin
-
Hayashi K, Hayashi T, Sun HD, et al. Potentiation of ganciclovir toxicity in the herpes simplex virus thymidine kinase/ganciclovir administration system by ponicidin. Cancer Gene Ther 2000; 7: 45-52.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 45-52
-
-
Hayashi, K.1
Hayashi, T.2
Sun, H.D.3
-
35
-
-
0016302756
-
Induction of both thymidine and deoxythymidine kinase activity in herpes simplex virus
-
Jamieson AT, Gentry GA, Subak-Sharpe JH. Induction of both thymidine and deoxythymidine kinase activity in herpes simplex virus. J Gen Virol 1974; 24: 465-480.
-
(1974)
J Gen Virol
, vol.24
, pp. 465-480
-
-
Jamieson, A.T.1
Gentry, G.A.2
Subak-Sharpe, J.H.3
-
36
-
-
0028296865
-
Regulation of herpes simplex virus thymidine kinase in cells treated with a synergistic antiviral combination of α interferon and acyclovir
-
Taylor JL, Tom P, Guy J, et al. Regulation of herpes simplex virus thymidine kinase in cells treated with a synergistic antiviral combination of α interferon and acyclovir. Antimicrob Agents Chemother 1994; 38: 853-856.
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 853-856
-
-
Taylor, J.L.1
Tom, P.2
Guy, J.3
-
37
-
-
0021029814
-
A comparison of the antiviral agents 2′-nor-2′-deoxyguanosine and acyclovir: Uptake and phosphorylation in tissue culture and kinetics of in vitro inhibition of viral and cellular DNA polymerases by their respective triphosphates
-
Germershausen J, Bostedor R, Field AK, et al. A comparison of the antiviral agents 2′-nor-2′-deoxyguanosine and acyclovir: uptake and phosphorylation in tissue culture and kinetics of in vitro inhibition of viral and cellular DNA polymerases by their respective triphosphates. Biochem Biophys Res Commun 1983; 116: 360-367.
-
(1983)
Biochem Biophys Res Commun
, vol.116
, pp. 360-367
-
-
Germershausen, J.1
Bostedor, R.2
Field, A.K.3
-
38
-
-
0027428571
-
Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenografts
-
Fan Z, Baselga J, Masui H, et al. Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenografts. Cancer Res 1993; 53: 4637-4642.
-
(1993)
Cancer Res
, vol.53
, pp. 4637-4642
-
-
Fan, Z.1
Baselga, J.2
Masui, H.3
-
39
-
-
0027136229
-
Acyclovir diphosphate dimyristoylglycerol: A phospholipid prodrug with activity against acyclovir-resistant herpes simplex virus
-
Hostetler KY, Parker S, Sridhar CN, et al. Acyclovir diphosphate dimyristoylglycerol: A phospholipid prodrug with activity against acyclovir-resistant herpes simplex virus. Proc Natl Acad Si USA 1993; 90: 11835-11839.
-
(1993)
Proc Natl Acad Si USA
, vol.90
, pp. 11835-11839
-
-
Hostetler, K.Y.1
Parker, S.2
Sridhar, C.N.3
-
40
-
-
0020614981
-
Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2- propoxymethyl)guanine
-
Smee DF, Martin JC, Verherden JPH, et al. Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine. Antimicrob Agents Chemother 1983; 23: 676-682.
-
(1983)
Antimicrob Agents Chemother
, vol.23
, pp. 676-682
-
-
Smee, D.F.1
Martin, J.C.2
Verherden, J.P.H.3
-
41
-
-
0015493414
-
Metabolic coupling, ionic coupling and cell contacts
-
Gilula NB, Reeves OR, Steinbach A. Metabolic coupling, ionic coupling and cell contacts. Nature 1972; 235: 262-265.
-
(1972)
Nature
, vol.235
, pp. 262-265
-
-
Gilula, N.B.1
Reeves, O.R.2
Steinbach, A.3
-
42
-
-
0027787053
-
In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy
-
Bi WL, Parysek LM, Wamick R, et al. In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy. Hum Gene Ther 1993; 4: 725-731.
-
(1993)
Hum Gene Ther
, vol.4
, pp. 725-731
-
-
Bi, W.L.1
Parysek, L.M.2
Wamick, R.3
-
43
-
-
0028864786
-
The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro
-
Fick J, Barker FGI, Dazin P, et al. The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro. Proc Natl Acad Sci U S A 1995; 92: 11071-11075.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11071-11075
-
-
Fick, J.1
Barker, F.G.I.2
Dazin, P.3
-
44
-
-
0029913138
-
Gap junctions play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro
-
Elshami AA, Saavedra A, Zhang H, et al. Gap junctions play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ ganciclovir system in vitro. Gene Ther 1996; 3: 85-92.
-
(1996)
Gene Ther
, vol.3
, pp. 85-92
-
-
Elshami, A.A.1
Saavedra, A.2
Zhang, H.3
-
45
-
-
0029996360
-
Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins
-
Mesnil M, Piccoli C, Tiraby G, et al. Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins. Proc Natl Acad Sci U S A 1996; 93: 1831-1835.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 1831-1835
-
-
Mesnil, M.1
Piccoli, C.2
Tiraby, G.3
-
46
-
-
0028939358
-
Negative growth control of HeLa cells by connexin gene: Connexin species specificity
-
Mesnil M, Krutovskikh V, Piccoli C, et al. Negative growth control of HeLa cells by connexin gene: connexin species specificity. Cancer Res 1995; 55: 629-639.
-
(1995)
Cancer Res
, vol.55
, pp. 629-639
-
-
Mesnil, M.1
Krutovskikh, V.2
Piccoli, C.3
-
47
-
-
0034887138
-
Efficacy of the bystander effect in the herpes simplex virus thymidine kinase-mediated gene therapy is influenced by the expression of connexin 43 in the target cells
-
Namba H, Iwadate Y, Kawamura K, et al. Efficacy of the bystander effect in the herpes simplex virus thymidine kinase-mediated gene therapy is influenced by the expression of connexin 43 in the target cells. Cancer Gene Ther 2001; 8: 414-420.
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 414-420
-
-
Namba, H.1
Iwadate, Y.2
Kawamura, K.3
-
48
-
-
0024563451
-
The actions of retinoids on cellular growth correlate with their actions on gap junctional communication
-
Mahtha PP, Bertram JS, Leewanstein WR. The actions of retinoids on cellular growth correlate with their actions on gap junctional communication. J Cell Biol 1989; 108: 1053-1065.
-
(1989)
J Cell Biol
, vol.108
, pp. 1053-1065
-
-
Mahtha, P.P.1
Bertram, J.S.2
Leewanstein, W.R.3
-
49
-
-
0030801745
-
Retinoids augment the bystander effect in vitro and in vivo herpes simplex virus thymidine kinase/ganciclovir-mediated gene therapy
-
Park JY, Elshami AA, Amine K, et al. Retinoids augment the bystander effect in vitro and in vivo herpes simplex virus thymidine kinase/ ganciclovir-mediated gene therapy. Gene Ther 1997; 4: 909-917.
-
(1997)
Gene Ther
, vol.4
, pp. 909-917
-
-
Park, J.Y.1
Elshami, A.A.2
Amine, K.3
-
50
-
-
0033153292
-
All-trans retinoic acid enhances gap junctional intercellular communication among renal epithelial cells in vitro treated with renal carcinogens
-
Watanabe J, Nomata K, Noguchi M, et al. All-trans retinoic acid enhances gap junctional intercellular communication among renal epithelial cells in vitro treated with renal carcinogens. Eur J Cancer 1999; 35: 1003-1008.
-
(1999)
Eur J Cancer
, vol.35
, pp. 1003-1008
-
-
Watanabe, J.1
Nomata, K.2
Noguchi, M.3
-
51
-
-
0034085228
-
Two-drug combinations that increase apoptosis and modulate bak and bcl-X(L) expression in human colon tumor cell lines transduced with herpes simplex virus thymidine kinase
-
McMasters RA, Wilbert TN, Jones KE, et al. Two-drug combinations that increase apoptosis and modulate bak and bcl-X(L) expression in human colon tumor cell lines transduced with herpes simplex virus thymidine kinase. Cancer Gene Ther 2000; 7: 563-573.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 563-573
-
-
McMasters, R.A.1
Wilbert, T.N.2
Jones, K.E.3
-
52
-
-
0033933045
-
Thymidine kinase gene therapy with concomitant topotecan chemotherapy for recurrent ovarian cancer
-
Hasenburg A, Tong XW, Rojas-Martinez A, et al. Thymidine kinase gene therapy with concomitant topotecan chemotherapy for recurrent ovarian cancer. Cancer Gene Ther 2000; 7: 839-852.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 839-852
-
-
Hasenburg, A.1
Tong, X.W.2
Rojas-Martinez, A.3
-
53
-
-
0034662464
-
Pharmacological modulation of the bystander effect in the herpes simplex virus thymidine kinase/ganciclovir gene therapy system: Effects of dibutyril adenosine 3′5′-cyclic monophosphate, alpha-glycyrrhetinic acid, and cytosine arabinoside
-
Robe PA, Princen F, Martin D, et al. Pharmacological modulation of the bystander effect in the herpes simplex virus thymidine kinase/ ganciclovir gene therapy system: effects of dibutyril adenosine 3′5′-cyclic monophosphate, alpha-glycyrrhetinic acid, and cytosine arabinoside. Biochem Pharmacol 2000; 60: 241-249.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 241-249
-
-
Robe, P.A.1
Princen, F.2
Martin, D.3
-
54
-
-
0032747138
-
Enzyme prodrug gene therapy: Synergistic use of the herpes simplex virus-cellular thymidine kinase/ganciclovir system and thymidylate synthase inhibitors for the treatment of colon cancer
-
Wilder O, Blasese RM, Candotti F. Enzyme prodrug gene therapy: synergistic use of the herpes simplex virus-cellular thymidine kinase/ ganciclovir system and thymidylate synthase inhibitors for the treatment of colon cancer. Cancer Res 1999; 59: 5233-5238.
-
(1999)
Cancer Res
, vol.59
, pp. 5233-5238
-
-
Wilder, O.1
Blasese, R.M.2
Candotti, F.3
-
55
-
-
0032854872
-
Use of protamine to augment adenovirus-mediated cancer gene therapy
-
Lanuti M, Kouri CE, Force S, et al. Use of protamine to augment adenovirus-mediated cancer gene therapy. Gene Ther 1999; 6: 1600-1610.
-
(1999)
Gene Ther
, vol.6
, pp. 1600-1610
-
-
Lanuti, M.1
Kouri, C.E.2
Force, S.3
-
56
-
-
0034654516
-
Synergistic enhancement of herpes simplex virus thymidine kinase /ganciclovir-mediated cytotoxicity by hydroxyurea
-
Boucher PD, Ostruszka LJ, Shewach DS. Synergistic enhancement of herpes simplex virus thymidine kinase/ganciclovir-mediated cytotoxicity by hydroxyurea. Cancer Res 2000; 60: 1631-1636.
-
(2000)
Cancer Res
, vol.60
, pp. 1631-1636
-
-
Boucher, P.D.1
Ostruszka, L.J.2
Shewach, D.S.3
-
57
-
-
0036045454
-
Hydroxyurea significantly enhances tumor growth delay in vivo with herpes simplex virus thymidine kinase/ganciclovir gene therapy
-
Boucher PD, Ostruszka LJ, Murphy PJM, et al. Hydroxyurea significantly enhances tumor growth delay in vivo with herpes simplex virus thymidine kinase/ganciclovir gene therapy. Gene Ther 2002; 9: 1023-1030.
-
(2002)
Gene Ther
, vol.9
, pp. 1023-1030
-
-
Boucher, P.D.1
Ostruszka, L.J.2
Murphy, P.J.M.3
-
58
-
-
0000345653
-
Two chemotypes of Scoparia dulcis in Paraguay
-
Hayashi T, Okamura K, Kawasaki M, et al. Two chemotypes of Scoparia dulcis in Paraguay. Phytochemisty 1991; 30: 3617-3620.
-
(1991)
Phytochemisty
, vol.30
, pp. 3617-3620
-
-
Hayashi, T.1
Okamura, K.2
Kawasaki, M.3
|