Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracranial gliomas

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 23, 2000, Pages 12846-12851

  Aboody, Karen S ^a,c   Brown, Alice ^a   Rainov, Nikolai G ^a   Bower, Kate A ^a   Liu, Shaoxiong ^a   Yang, Wendy ^a   Small, Juan E ^a   Herrlinger, Ulrich ^a   Ourednik, Vaclav ^a   Black, Peter McL ^b   Breakefield, Xandra O ^a   Snyder, Evan Y ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c Layton Biosciences   (United States)

Author keywords

Brain tumors; Gene therapy; Migration; Transplantation; Vascular

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN TUMOR; CELL MIGRATION; CELL TRANSPLANTATION; CELLULAR DISTRIBUTION; CONFERENCE PAPER; GENE EXPRESSION; GLIOBLASTOMA; GLIOMA; HUMAN; HUMAN CELL; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; STEM CELL TRANSPLANTATION; ANIMAL; ARTICLE; BRAIN; CELL MOTION; CYTOLOGY; DISEASE MODEL; FEMALE; FISCHER 344 RAT; GENE THERAPY; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; METHODOLOGY; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; PLANT GROWTH; STEM CELL;

ANIMALIA; RODENTIA;

CYTOSINE DEAMINASE; DEAMINASE;

ANIMALS; BRAIN; BRAIN NEOPLASMS; CELL MOVEMENT; CYTOSINE DEAMINASE; DISEASE MODELS, ANIMAL; FEMALE; GENE THERAPY; GLIOBLASTOMA; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MICE; MICE, NUDE; NEURONS; NUCLEOSIDE DEAMINASES; RATS; RATS, INBRED F344; STEM CELLS; TROPISM;

EID: 0034619328     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.23.12846     Document Type: Article

References (24)

1. Black, P. M. & Loeffler, J., eds. (1997) Cancer of the Nervous System (Blackwell, Oxford).
2. Kramm, C. M, Sena-Esteves M., Barnett F. H., Rainov, N. G., Schuback, D. E., Yu, J. S., Pechan, P. A., Paulus, W., Chiocca, E. A. & Breakefield, X. O. (1995) Brain Pathol. 5, 345-381.
3. Gage, F. H. (2000) Science 287, 1433-1438.
4. McKay, R. (1997) Science 276, 66-71.
5. Flax, J. D., Aurora, S., Yang, C., Simonin, C., Wills, A. M., Billinghurst, M. J., Sidman, R. L., Wolfe, J. H., Kim, S. U. & Snyder, E. Y. (1998) Nat. Biotech. 16, 1033-1039.
6. Weiss, S., Reynolds, B. A., Vescovi, A. L., Morshead, C. & Van der Kooy, D. (1996) Trends Neurosci. 19, 387-393.
7. Alvarez-Buylla, A. & Temple, S. (1998) J. Neurobiol. 36, 105-314.
8. Snyder, E. Y., Taylor, R. M. & Wolfe, J. H. (1995) Nature (London) 374, 367-370.
9. Yandava, B. D., Billinghurst, L. L. & Snyder, E. Y. (1999) Proc. Natl. Acad. Sci. USA 96, 7029-7034.
10. Lynch, W. P., Sharpe, A. H. & Snyder, E. Y. (1999) J. Virol. 73, 6841-6851.
11. Kruse, C. A., Molleston, M., Parks, E. P., Schiltz, P. M., Kleinschmidt-DeMasters, B. K. & Hickey, W. F. (1994) J. Neurooncol. 22, 191-200.
12. Aboody-Guterman, K. S., Pechan, P. A., Rainov, N. G., Sena-Esteves, M., Snyder, E. Y., Wild, P., Schraner, E., Tobler, K., Breakefield, X. O. & Fraefel, C. (1997) NeuroReport 8, 3801-3808.
13. Snyder, E. Y., Yoon, C. H., Flax, J. D. & Macklis, J. D. (1997) Proc. Natl. Acad. Sci. USA 94, 11663-11668.
14. Yuan, F., Salehi H. A., Boucher Y., Vasthari U. S., Tuma R. F. & Jain R. K. (1994) Cancer Res. 54, 4564-4568.
15. Tamiya, T., Wei, M. X., Chase, M., Ono, Y., Lee, F., Breakefield, X. O. & Chiocca, E. A. (1995) Gene Ther. 2, 531-538.
16. Morgenstern, J. P. & Land, H. (1990) Nucleic Acids Res. 18, 3587-3596.
17. Sena-Esteves, M., Saeki, Y., Camp, S., Chiocca, E. A. & Breakefield, X. O. (1999) J. Virol 73, 10426-10439.
18. Pear, W. S., Nolan, G. P., Scott, M. L. & Baltimore, D. (1993) Proc. Natl. Acad. Sci. USA 90, 8392-8396.
19. Ko, L., Koestner, A. & Wechsler, W. (1980) Acta Neuropathol. 51, 23-34.
20. Topf, N., Worgall, S., Hackett, N. R.& Crystal, R. G. (1998) Gene Ther. 5, 507-513.
21. Mullen, C., Kilstrup, M. & Blaese, R. M. (1992) Proc. Natl. Acad. Sci. USA 89, 33-37.
22. Huber, B. E., Austin, E. A., Richards, C. A., Davis, S. T. & Good, S. (1994) Proc. Natl. Acad. Sci. USA 91, 8302-8306.
23. Benedetti, S., Pirola B., Polio, B., Gagrassi, L., Briuzzone, M. G., Rigamonti, D., Galli, R., Selleri, S., DiMeco, R., DeFraja, C., et al. (2000) Nat. Med. 6, 447-450.
24. Herrlinger, U., Woiciechowski, C., Aboody, K. S., Jacobs, A. H., Rainov, N. G., Snyder, E. Y. & Breakefield, X. O. (2000) Mol. Ther. 1, 347-357.