Depression and treatment response: Dynamic interplay of signaling pathways and altered neural processes

Cellular and Molecular Life Sciences

Volumn 70, Issue 1, 2013, Pages 39-53

  Duric, Vanja ^a   Duman, Ronald S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Depression; Ketamine; MKP 1; Molecular mechanisms; Neurotrophins; Stress

Indexed keywords

ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; ESCITALOPRAM; FIBROBLAST GROWTH FACTOR 2; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; INTERLEUKIN 1; INTERLEUKIN 6; KETAMINE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROTROPHIC FACTOR; PROTEIN VGF; RECOMBINANT FIBROBLAST GROWTH FACTOR; SEROTONIN UPTAKE INHIBITOR; SOMATOMEDIN C; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN; WNT PROTEIN;

ANTIDEPRESSANT ACTIVITY; ANXIETY DISORDER; AUTOPSY; CHRONIC STRESS; DEPRESSION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HIPPOCAMPUS; HUMAN; INTRACELLULAR SIGNALING; MAJOR DEPRESSION; MOLECULAR DYNAMICS; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEUROIMAGING; NONHUMAN; PREFRONTAL CORTEX; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SYNAPTOGENESIS; TRANQUILIZING ACTIVITY; TREATMENT RESPONSE;

ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSIVE DISORDER; HIPPOCAMPUS; HUMANS; NERVE GROWTH FACTORS; PREFRONTAL CORTEX; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL; TOR SERINE-THREONINE KINASES; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA;

EID: 84872320031     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1020-7     Document Type: Review

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