메뉴 건너뛰기




Volumn 23, Issue 6, 2011, Pages 730-737

Cell atrophy and loss in depression: Reversal by antidepressant treatment

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; GLUTAMIC ACID; GLYCOGEN SYNTHASE KINASE 3; KETAMINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; N METHYL DEXTRO ASPARTIC ACID; NEUROTROPHIC FACTOR; WNT PROTEIN;

EID: 82555205300     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2011.09.002     Document Type: Review
Times cited : (156)

References (84)
  • 1
    • 0037831023 scopus 로고    scopus 로고
    • The epidemiology of major depressive disorder: results from the national comorbidity Survey Replication (NCS-R)
    • Kessler R., Berglund P., Demler O., Jin R., Koretz D., Merikangas K.R. The epidemiology of major depressive disorder: results from the national comorbidity Survey Replication (NCS-R). J Am Med Assoc 2003, 289:3095-3105.
    • (2003) J Am Med Assoc , vol.289 , pp. 3095-3105
    • Kessler, R.1    Berglund, P.2    Demler, O.3    Jin, R.4    Koretz, D.5    Merikangas, K.R.6
  • 2
    • 36549030795 scopus 로고    scopus 로고
    • Stress, depression, and neuroplasticity: a convergence of mechanisms
    • Pittenger C., Duman R.S. Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology 2008, 33:88-109.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 88-109
    • Pittenger, C.1    Duman, R.S.2
  • 3
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan V., Nestler E.J. The molecular neurobiology of depression. Nature 2008, 455:894-902.
    • (2008) Nature , vol.455 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 7
    • 38349116509 scopus 로고    scopus 로고
    • Stress blunts serotonin- and hypocretin-evoked EPSCs in prefrontal cortex: role of corticosterone-mediated apical dendritic atrophy
    • Liu R.-J., Aghajanian G.K. Stress blunts serotonin- and hypocretin-evoked EPSCs in prefrontal cortex: role of corticosterone-mediated apical dendritic atrophy. Proc Natl Acad Sci U S A 2008, 105:359-364.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 359-364
    • Liu, R.-J.1    Aghajanian, G.K.2
  • 8
    • 1642421311 scopus 로고    scopus 로고
    • Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex
    • Radley J., Sisti H.M., Hao J., Rocher A.B., McCall T., Hof P.R., McEwen B.S., Morrison J.H. Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex. Neuroscience 2004, 125:1-6.
    • (2004) Neuroscience , vol.125 , pp. 1-6
    • Radley, J.1    Sisti, H.M.2    Hao, J.3    Rocher, A.B.4    McCall, T.5    Hof, P.R.6    McEwen, B.S.7    Morrison, J.H.8
  • 9
    • 23444432520 scopus 로고    scopus 로고
    • Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress
    • Radley J., Rocher A.B., Janssen W.G., Hof P.R., McEwen B.S., Morrison J.H. Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress. Exp Neurol 2005, 196:199-203.
    • (2005) Exp Neurol , vol.196 , pp. 199-203
    • Radley, J.1    Rocher, A.B.2    Janssen, W.G.3    Hof, P.R.4    McEwen, B.S.5    Morrison, J.H.6
  • 11
    • 79953166373 scopus 로고    scopus 로고
    • Glutamate N-methyl-d-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure
    • Li N., Liu R.J., Dwyer J.M., Banasr M., Lee B., Son H., Li X.Y., Aghajanian G., Duman R.S. Glutamate N-methyl-d-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. Biol Psychiatry 2011, 69:754-761.
    • (2011) Biol Psychiatry , vol.69 , pp. 754-761
    • Li, N.1    Liu, R.J.2    Dwyer, J.M.3    Banasr, M.4    Lee, B.5    Son, H.6    Li, X.Y.7    Aghajanian, G.8    Duman, R.S.9
  • 12
    • 34447629382 scopus 로고    scopus 로고
    • Physiology and neurobiology of stress and adaptation: central role of the brain
    • McEwen B. Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol Rev 2007, 87:873-904.
    • (2007) Physiol Rev , vol.87 , pp. 873-904
    • McEwen, B.1
  • 13
    • 77249137412 scopus 로고    scopus 로고
    • Correlation analysis between genome-wide expression profiles and cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders
    • Kim S., Webster M.J. Correlation analysis between genome-wide expression profiles and cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders. Mol Psychiatry 2010, 15:326-336.
    • (2010) Mol Psychiatry , vol.15 , pp. 326-336
    • Kim, S.1    Webster, M.J.2
  • 14
    • 79953192475 scopus 로고    scopus 로고
    • Differential expression of synaptic proteins after chronic restraint stress in rat prefrontal cortex and hippocampus
    • Muller H.K., Wegener G., Popoli M., Elfving B. Differential expression of synaptic proteins after chronic restraint stress in rat prefrontal cortex and hippocampus. Brain Res 2011, 1385:26-37.
    • (2011) Brain Res , vol.1385 , pp. 26-37
    • Muller, H.K.1    Wegener, G.2    Popoli, M.3    Elfving, B.4
  • 15
    • 33746279595 scopus 로고    scopus 로고
    • Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment
    • Czeh B., Simon M., Schmelting B., Hiemke C., Fuchs E. Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment. Neuropsychopharmacology 2006, 31:1616-1626.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1616-1626
    • Czeh, B.1    Simon, M.2    Schmelting, B.3    Hiemke, C.4    Fuchs, E.5
  • 16
    • 54149093900 scopus 로고    scopus 로고
    • Glial loss in the prefrontal cortex is sufficient to induce depressive-like behaviors
    • Banasr M., Duman R.S. Glial loss in the prefrontal cortex is sufficient to induce depressive-like behaviors. Biol Psychiatry 2008, 64:863-870.
    • (2008) Biol Psychiatry , vol.64 , pp. 863-870
    • Banasr, M.1    Duman, R.S.2
  • 17
    • 33846251906 scopus 로고    scopus 로고
    • GABAergic neurons immunoreactive for calcium binding proteins are reduced in the prefrontal cortex in major depression
    • Rajkowska G., O'Dwyer G., Teleki Z., Stockmeier C.A., Miguel-Hidalgo J.J. GABAergic neurons immunoreactive for calcium binding proteins are reduced in the prefrontal cortex in major depression. Neuropsychopharmacology 2007, 32:471-482.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 471-482
    • Rajkowska, G.1    O'Dwyer, G.2    Teleki, Z.3    Stockmeier, C.A.4    Miguel-Hidalgo, J.J.5
  • 18
    • 75849156656 scopus 로고    scopus 로고
    • Reduced density of calbindin immunoreactive GABAergic neurons in the occipital cortex in major depression: relevance to neuroimaging studies
    • Maciag D., Hughes J., O'Dwyer G., Pride Y., Stockmeier C.A., Sanacora G., Rajkowska G. Reduced density of calbindin immunoreactive GABAergic neurons in the occipital cortex in major depression: relevance to neuroimaging studies. Biol Psychiatry 2010, 67:465-470.
    • (2010) Biol Psychiatry , vol.67 , pp. 465-470
    • Maciag, D.1    Hughes, J.2    O'Dwyer, G.3    Pride, Y.4    Stockmeier, C.A.5    Sanacora, G.6    Rajkowska, G.7
  • 19
    • 75849155175 scopus 로고    scopus 로고
    • Cortical inhibition, gamma-aminobutyric acid, and major depression: there is plenty of smoke but is there fire?
    • Sanacora G. Cortical inhibition, gamma-aminobutyric acid, and major depression: there is plenty of smoke but is there fire?. Biol Psychiatry 2010, 67:397-398.
    • (2010) Biol Psychiatry , vol.67 , pp. 397-398
    • Sanacora, G.1
  • 20
    • 34247628030 scopus 로고    scopus 로고
    • GABAergic contributions to the pathophysiology of depression and the mechanism of antidepressant action
    • Sanacora G., Saricicek A. GABAergic contributions to the pathophysiology of depression and the mechanism of antidepressant action. CNS Neurol Disord Drug Targets 2007, 6:127-140.
    • (2007) CNS Neurol Disord Drug Targets , vol.6 , pp. 127-140
    • Sanacora, G.1    Saricicek, A.2
  • 21
    • 34250344214 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis as target for the treatment of depression
    • Drew M., Hen R. Adult hippocampal neurogenesis as target for the treatment of depression. CNS Neurol Disord Drug Targets 2007, 6:205-218.
    • (2007) CNS Neurol Disord Drug Targets , vol.6 , pp. 205-218
    • Drew, M.1    Hen, R.2
  • 22
    • 40449095164 scopus 로고    scopus 로고
    • Regulation of neurogenesis and gliogenesis by stress and antidepressant treatment
    • Banasr M., Duman R.S. Regulation of neurogenesis and gliogenesis by stress and antidepressant treatment. CNS Neurol Disord Drug Targets 2007, 6:311-320.
    • (2007) CNS Neurol Disord Drug Targets , vol.6 , pp. 311-320
    • Banasr, M.1    Duman, R.S.2
  • 23
    • 34548348778 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis in depression
    • Sahay A., Hen R. Adult hippocampal neurogenesis in depression. Nat Neurosci 2007, 10:1110-1115.
    • (2007) Nat Neurosci , vol.10 , pp. 1110-1115
    • Sahay, A.1    Hen, R.2
  • 24
    • 80052050190 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis buffers stress responses and depressive behaviour
    • Snyder J.S., Soumier A., Brewer M., Pickel J., Cameron H.A. Adult hippocampal neurogenesis buffers stress responses and depressive behaviour. Nature 2011, 476:458-461.
    • (2011) Nature , vol.476 , pp. 458-461
    • Snyder, J.S.1    Soumier, A.2    Brewer, M.3    Pickel, J.4    Cameron, H.A.5
  • 26
    • 42949123365 scopus 로고    scopus 로고
    • Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders
    • Sanacora G., Zarate C.A., Krystal J.H., Manji H.K. Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nat Rev Drug Discov 2008, 7:426-437.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 426-437
    • Sanacora, G.1    Zarate, C.A.2    Krystal, J.H.3    Manji, H.K.4
  • 27
    • 0030860045 scopus 로고    scopus 로고
    • Stress effects on morphology and function of the hippocampus
    • McEwen B.S., Magarinos A.M. Stress effects on morphology and function of the hippocampus. Ann N Y Acad Sci 1997, 821:271-284.
    • (1997) Ann N Y Acad Sci , vol.821 , pp. 271-284
    • McEwen, B.S.1    Magarinos, A.M.2
  • 28
    • 0028027113 scopus 로고
    • Glucocorticoids mediate the stress-induced extracellular accumulation of glutamate
    • Moghaddam B., Bolinao M.L., Stein-Behrens B., Sapolsky R. Glucocorticoids mediate the stress-induced extracellular accumulation of glutamate. Brain Res 1994, 655:251-254.
    • (1994) Brain Res , vol.655 , pp. 251-254
    • Moghaddam, B.1    Bolinao, M.L.2    Stein-Behrens, B.3    Sapolsky, R.4
  • 29
    • 0027231058 scopus 로고
    • Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: comparison to hippocampus and basal ganglia
    • Moghaddam B. Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: comparison to hippocampus and basal ganglia. J Neurochem 1993, 60:1650-1657.
    • (1993) J Neurochem , vol.60 , pp. 1650-1657
    • Moghaddam, B.1
  • 30
    • 72049095334 scopus 로고    scopus 로고
    • Reduced expression of glutamate transporters vGluT1, EAAT2 and EAAT4 in learned helpless rats, an animal model of depression
    • Zink M., Vollmayr B., Gebicke-Haerter P.J., Henn F.A. Reduced expression of glutamate transporters vGluT1, EAAT2 and EAAT4 in learned helpless rats, an animal model of depression. Neuropharmacology 2010, 58:465-473.
    • (2010) Neuropharmacology , vol.58 , pp. 465-473
    • Zink, M.1    Vollmayr, B.2    Gebicke-Haerter, P.J.3    Henn, F.A.4
  • 32
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman R., Monteggia L.M. A neurotrophic model for stress-related mood disorders. Biol Psychiatry 2006, 59:1116-1127.
    • (2006) Biol Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.1    Monteggia, L.M.2
  • 33
    • 38449090175 scopus 로고    scopus 로고
    • Elucidating the role of brain-derived neurotrophic factor in the brain
    • Monteggia L. Elucidating the role of brain-derived neurotrophic factor in the brain. Am J Psychiatry 2007, 164:1790.
    • (2007) Am J Psychiatry , vol.164 , pp. 1790
    • Monteggia, L.1
  • 36
    • 82555182808 scopus 로고    scopus 로고
    • Aghajanian GK: BDNF Met allele decreases the density and function of spine/synapses in the prefrontal cortex and blocks synaptogenic and antidepressant effects of ketamine
    • in press
    • Liu R., Lee F.S., Li X.Y., Bambico F., Duman R.S. Aghajanian GK: BDNF Met allele decreases the density and function of spine/synapses in the prefrontal cortex and blocks synaptogenic and antidepressant effects of ketamine. Biological Psychiatry 2011, in press.
    • (2011) Biological Psychiatry
    • Liu, R.1    Lee, F.S.2    Li, X.Y.3    Bambico, F.4    Duman, R.S.5
  • 37
    • 33847308098 scopus 로고    scopus 로고
    • A role for MAPK signaling in behavioral models of depression and antidepressant treatment
    • Duman C., Schlesinger L., Kodama M., Russell D.S., Duman R.S. A role for MAPK signaling in behavioral models of depression and antidepressant treatment. Biol Psychiatry 2007, 61:661-670.
    • (2007) Biol Psychiatry , vol.61 , pp. 661-670
    • Duman, C.1    Schlesinger, L.2    Kodama, M.3    Russell, D.S.4    Duman, R.S.5
  • 41
    • 43649084022 scopus 로고    scopus 로고
    • Repeated unpredictable stress and antidepressants differentially regulate expression of the bcl-2 family of apoptotic genes in rat cortical, hippocampal, and limbic brain structures
    • Kosten T.A., Galloway M.P., Duman R.S., Russell D.S., D'Sa C. Repeated unpredictable stress and antidepressants differentially regulate expression of the bcl-2 family of apoptotic genes in rat cortical, hippocampal, and limbic brain structures. Neuropsychopharmacology 2008, 33:1545-1558.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 1545-1558
    • Kosten, T.A.1    Galloway, M.P.2    Duman, R.S.3    Russell, D.S.4    D'Sa, C.5
  • 42
    • 40949125640 scopus 로고    scopus 로고
    • Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: the role of glycogen-synthase-kinase-3beta
    • Silva R., Mesquita A.R., Bessa J., Sousa J.C., Sotiropoulos I., Leao P., Almeida O.F., Sousa N. Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: the role of glycogen-synthase-kinase-3beta. Neuroscience 2008, 152:656-669.
    • (2008) Neuroscience , vol.152 , pp. 656-669
    • Silva, R.1    Mesquita, A.R.2    Bessa, J.3    Sousa, J.C.4    Sotiropoulos, I.5    Leao, P.6    Almeida, O.F.7    Sousa, N.8
  • 44
    • 70149104789 scopus 로고    scopus 로고
    • Cellular mechanisms underlying affective resiliency: the role of glucocorticoid receptor- and mitochondrially-mediated plasticity
    • Hunsberger J.G., Austin D.R., Chen G., Manji H.K. Cellular mechanisms underlying affective resiliency: the role of glucocorticoid receptor- and mitochondrially-mediated plasticity. Brain Res 2009, 1293:76-84.
    • (2009) Brain Res , vol.1293 , pp. 76-84
    • Hunsberger, J.G.1    Austin, D.R.2    Chen, G.3    Manji, H.K.4
  • 45
    • 48149096538 scopus 로고    scopus 로고
    • Chronic unpredictable stress promotes neuronal apoptosis in the cerebral cortex
    • Bachis A., Cruz M.I., Nosheny R.L., Mocchetti I. Chronic unpredictable stress promotes neuronal apoptosis in the cerebral cortex. Neurosci Lett 2008, 442:104-108.
    • (2008) Neurosci Lett , vol.442 , pp. 104-108
    • Bachis, A.1    Cruz, M.I.2    Nosheny, R.L.3    Mocchetti, I.4
  • 47
    • 77955226061 scopus 로고    scopus 로고
    • SCLM, total saponins extracted from Chaihu-jia-longgu-muli-tang, reduces chronic mild stress-induced apoptosis in the hippocampus in mice
    • Liu Y., Ma S., Qu R. SCLM, total saponins extracted from Chaihu-jia-longgu-muli-tang, reduces chronic mild stress-induced apoptosis in the hippocampus in mice. Pharm Biol 2010, 48:840-848.
    • (2010) Pharm Biol , vol.48 , pp. 840-848
    • Liu, Y.1    Ma, S.2    Qu, R.3
  • 49
    • 78649555853 scopus 로고    scopus 로고
    • Imipramine treatment increases the number of hippocampal synapses and neurons in a genetic animal model of depression
    • Chen F., Madsen T.M., Wegener G., Nyengaard J.R. Imipramine treatment increases the number of hippocampal synapses and neurons in a genetic animal model of depression. Hippocampus 2010, 20:1376-1384.
    • (2010) Hippocampus , vol.20 , pp. 1376-1384
    • Chen, F.1    Madsen, T.M.2    Wegener, G.3    Nyengaard, J.R.4
  • 50
    • 11144267133 scopus 로고    scopus 로고
    • Chronic stress decreases the number of parvalbumin-immunoreactive interneurons in the hippocampus: prevention by treatment with a substance P receptor (NK1) antagonist
    • Czeh B., Simon M., van der Hart M.G., Schmelting B., Hesselink M.B., Fuchs E. Chronic stress decreases the number of parvalbumin-immunoreactive interneurons in the hippocampus: prevention by treatment with a substance P receptor (NK1) antagonist. Neuropsychopharmacology 2005, 30:67-79.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 67-79
    • Czeh, B.1    Simon, M.2    van der Hart, M.G.3    Schmelting, B.4    Hesselink, M.B.5    Fuchs, E.6
  • 51
    • 77951880669 scopus 로고    scopus 로고
    • Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole
    • Banasr M., Chowdhury G.M., Terwilliger R., Newton S.S., Duman R.S., Behar K.L., Sanacora G. Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole. Mol Psychiatry 2010, 15:501-511.
    • (2010) Mol Psychiatry , vol.15 , pp. 501-511
    • Banasr, M.1    Chowdhury, G.M.2    Terwilliger, R.3    Newton, S.S.4    Duman, R.S.5    Behar, K.L.6    Sanacora, G.7
  • 52
    • 68149110223 scopus 로고    scopus 로고
    • Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression
    • Koo J., Duman R.S. Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression. Curr Opin Invest Drugs 2009, 10:664-671.
    • (2009) Curr Opin Invest Drugs , vol.10 , pp. 664-671
    • Koo, J.1    Duman, R.S.2
  • 53
    • 78349241786 scopus 로고    scopus 로고
    • Linking molecules to mood: new insight into the biology of depression
    • Krishnan V., Nestler E.J. Linking molecules to mood: new insight into the biology of depression. Am J Psychiatry 2010, 167:1305-1320.
    • (2010) Am J Psychiatry , vol.167 , pp. 1305-1320
    • Krishnan, V.1    Nestler, E.J.2
  • 54
    • 34548395111 scopus 로고    scopus 로고
    • The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior
    • Schmidt H., Duman R.S. The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behav Pharmacol 2007, 18:391-418.
    • (2007) Behav Pharmacol , vol.18 , pp. 391-418
    • Schmidt, H.1    Duman, R.S.2
  • 55
    • 79960835306 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in adult hippocampal neurogenesis: implications for the pathophysiology and treatment of depression
    • [Epub ahead of print]
    • Fournier N., Duman R.S. Role of vascular endothelial growth factor in adult hippocampal neurogenesis: implications for the pathophysiology and treatment of depression. Behav Brain Res 2011, [Epub ahead of print].
    • (2011) Behav Brain Res
    • Fournier, N.1    Duman, R.S.2
  • 56
    • 0026493735 scopus 로고
    • Tianeptine attenuates stress-induced morphological changes in the hippocampus
    • Watanabe Y., Gould E., Daniels D.C., Cameron H., McEwen B.S. Tianeptine attenuates stress-induced morphological changes in the hippocampus. Eur J Pharmacol 1992, 222:157-162.
    • (1992) Eur J Pharmacol , vol.222 , pp. 157-162
    • Watanabe, Y.1    Gould, E.2    Daniels, D.C.3    Cameron, H.4    McEwen, B.S.5
  • 57
    • 48649083449 scopus 로고    scopus 로고
    • Brain derived neurotrophic factor (BDNF) contributes to the pain hypersensitivity following surgical incision in the rats
    • Li C., Xu J.M., Liu D., Zhang J.Y., Dai R.P. Brain derived neurotrophic factor (BDNF) contributes to the pain hypersensitivity following surgical incision in the rats. Mol Pain 2008, 4:27.
    • (2008) Mol Pain , vol.4 , pp. 27
    • Li, C.1    Xu, J.M.2    Liu, D.3    Zhang, J.Y.4    Dai, R.P.5
  • 58
    • 70349122023 scopus 로고    scopus 로고
    • VEGF signaling is required for the behavioral actions of 5-HT selective reuptake inhibitor antidepressants
    • Greene J., Banasr M., Duman R.S. VEGF signaling is required for the behavioral actions of 5-HT selective reuptake inhibitor antidepressants. Neuropsychopharmacology 2009, 34:2459-2468.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 2459-2468
    • Greene, J.1    Banasr, M.2    Duman, R.S.3
  • 59
    • 34248388548 scopus 로고    scopus 로고
    • VEGF is an essential mediator of neurogenic and behavioral actions of antidepressants
    • Warner-Schmidt J., Duman R.S. VEGF is an essential mediator of neurogenic and behavioral actions of antidepressants. Proc Natl Acad Sci U S A 2007, 104:4647-4652.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 4647-4652
    • Warner-Schmidt, J.1    Duman, R.S.2
  • 60
    • 32844458346 scopus 로고    scopus 로고
    • ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf
    • Dwivedi Y., Rizavi H.S., Conley R.R., Pandey G.N. ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf. Mol Psychiatry 2006, 11:86-98.
    • (2006) Mol Psychiatry , vol.11 , pp. 86-98
    • Dwivedi, Y.1    Rizavi, H.S.2    Conley, R.R.3    Pandey, G.N.4
  • 62
    • 78149305869 scopus 로고    scopus 로고
    • Negative regulator of MAP kinase is increased in depression and is necessary and sufficient for depressive behavior
    • Duric V., Banasr M., Licznerski P., Schmidt H., Stockmeier C., Simen A., Newton S.S., Duman R.S. Negative regulator of MAP kinase is increased in depression and is necessary and sufficient for depressive behavior. Nat Med 2010, 16:1328-1332.
    • (2010) Nat Med , vol.16 , pp. 1328-1332
    • Duric, V.1    Banasr, M.2    Licznerski, P.3    Schmidt, H.4    Stockmeier, C.5    Simen, A.6    Newton, S.S.7    Duman, R.S.8
  • 63
    • 25844452847 scopus 로고    scopus 로고
    • Mood stabilizers target cellular plasticity and resilience cascades: implications for the development of novel therapeutics
    • 173-102
    • Bachmann R.F., Schloesser R.J., Gould T.D., Manji H.K. Mood stabilizers target cellular plasticity and resilience cascades: implications for the development of novel therapeutics. Mol Neurobiol 2005, 32. 173-102.
    • (2005) Mol Neurobiol , vol.32
    • Bachmann, R.F.1    Schloesser, R.J.2    Gould, T.D.3    Manji, H.K.4
  • 64
    • 10644255687 scopus 로고    scopus 로고
    • AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
    • Gould T., Einat H., Bhat R., Manji H.K. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int J Neuropsychopharmacol 2004, 7:387-390.
    • (2004) Int J Neuropsychopharmacol , vol.7 , pp. 387-390
    • Gould, T.1    Einat, H.2    Bhat, R.3    Manji, H.K.4
  • 67
    • 79956041531 scopus 로고    scopus 로고
    • Lentivirally mediated GSK-3beta silencing in the hippocampal dentate gyrus induces antidepressant-like effects in stressed mice
    • Omata N., Chiu C.T., Moya P.R., Leng Y., Wang Z., Hunsberger J.G., Leeds P., Chuang D.M. Lentivirally mediated GSK-3beta silencing in the hippocampal dentate gyrus induces antidepressant-like effects in stressed mice. Int J Neuropsychopharmacol 2011, 14:711-717.
    • (2011) Int J Neuropsychopharmacol , vol.14 , pp. 711-717
    • Omata, N.1    Chiu, C.T.2    Moya, P.R.3    Leng, Y.4    Wang, Z.5    Hunsberger, J.G.6    Leeds, P.7    Chuang, D.M.8
  • 68
    • 33744903156 scopus 로고    scopus 로고
    • Calcium signals control Wnt-dependent dendrite growth
    • Alvania R.S., Chen X., Ginty D.D. Calcium signals control Wnt-dependent dendrite growth. Neuron 2006, 50:813-815.
    • (2006) Neuron , vol.50 , pp. 813-815
    • Alvania, R.S.1    Chen, X.2    Ginty, D.D.3
  • 69
    • 33744900895 scopus 로고    scopus 로고
    • Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB-dependent transcription of Wnt-2
    • Wayman G.A., Impey S., Marks D., Saneyoshi T., Grant W.F., Derkach V., Soderling T.R. Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB-dependent transcription of Wnt-2. Neuron 2006, 50:897-909.
    • (2006) Neuron , vol.50 , pp. 897-909
    • Wayman, G.A.1    Impey, S.2    Marks, D.3    Saneyoshi, T.4    Grant, W.F.5    Derkach, V.6    Soderling, T.R.7
  • 70
    • 67449097474 scopus 로고    scopus 로고
    • Ketamine and the next generation of antidepressants with a rapid onset of action
    • Machado-Vieira R., Salvadore G., Diazgranados N., Zarate C.A. Ketamine and the next generation of antidepressants with a rapid onset of action. Pharmacol Ther 2009, 123:143-150.
    • (2009) Pharmacol Ther , vol.123 , pp. 143-150
    • Machado-Vieira, R.1    Salvadore, G.2    Diazgranados, N.3    Zarate, C.A.4
  • 74
    • 80053025475 scopus 로고    scopus 로고
    • A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department
    • Larkin G.L., Beautrais A.L. A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department. Int J Neuropsychopharmacol 2011, 1-5.
    • (2011) Int J Neuropsychopharmacol , pp. 1-5
    • Larkin, G.L.1    Beautrais, A.L.2
  • 75
    • 68049121850 scopus 로고    scopus 로고
    • Effects of intravenous ketamine on explicit and implicit measures of suicidality in treatment-resistant depression
    • Price R.B., Nock M.K., Charney D.S., Mathew S.J. Effects of intravenous ketamine on explicit and implicit measures of suicidality in treatment-resistant depression. Biol Psychiatry 2009, 66:522-526.
    • (2009) Biol Psychiatry , vol.66 , pp. 522-526
    • Price, R.B.1    Nock, M.K.2    Charney, D.S.3    Mathew, S.J.4
  • 76
  • 78
    • 75749114797 scopus 로고    scopus 로고
    • MTOR signaling: at the crossroads of plasticity, memory and disease
    • Hoeffer C.A., Klann E. mTOR signaling: at the crossroads of plasticity, memory and disease. Trends Neurosci 2010, 33:67-75.
    • (2010) Trends Neurosci , vol.33 , pp. 67-75
    • Hoeffer, C.A.1    Klann, E.2
  • 81
    • 58149357209 scopus 로고    scopus 로고
    • Reduced levels of NR2A and NR2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depression
    • Feyissa A.M., Chandran A., Stockmeier C.A., Karolewicz B. Reduced levels of NR2A and NR2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depression. Prog Neuropsychopharmacol Biol Psychiatry 2009, 33:70-75.
    • (2009) Prog Neuropsychopharmacol Biol Psychiatry , vol.33 , pp. 70-75
    • Feyissa, A.M.1    Chandran, A.2    Stockmeier, C.A.3    Karolewicz, B.4
  • 82
    • 45549092746 scopus 로고    scopus 로고
    • Novel drugs and therapeutic targets for severe mood disorders
    • Mathew S.J., Manji H.K., Charney D.S. Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology 2008, 33:2080-2092.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2080-2092
    • Mathew, S.J.1    Manji, H.K.2    Charney, D.S.3
  • 84
    • 67650473167 scopus 로고    scopus 로고
    • Positive AMPA receptor modulation rapidly stimulates BDNF release and increases dendritic mRNA translation
    • Jourdi H., Hsu Y.T., Zhou M., Qin Q., Bi X., Baudry M. Positive AMPA receptor modulation rapidly stimulates BDNF release and increases dendritic mRNA translation. J Neurosci 2009, 29:8688-8697.
    • (2009) J Neurosci , vol.29 , pp. 8688-8697
    • Jourdi, H.1    Hsu, Y.T.2    Zhou, M.3    Qin, Q.4    Bi, X.5    Baudry, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.