Recombinase-mediated cassette exchange (RMCE) - A rapidly-expanding toolbox for targeted genomic modifications

Gene

Volumn 515, Issue 1, 2013, Pages 1-27

  Turan, Soeren ^a   Zehe, Christoph ^b   Kuehle, Johannes ^a   Qiao, Junhua ^c   Bode, Juergen ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Cellca GmbH   (Germany)

^c WUXI APPTEC   (China)

Author keywords

FRT twin sites; IPS reprogramming; PhiC31 integrase; Serial RMCE; Site specific Tyr recombinases (Flp Cre)

Indexed keywords

CRE RECOMBINASE; LENTIVIRUS VECTOR; RECOMBINASE; SERINE; TYROSINE;

CELL DIFFERENTIATION; CHROMOSOME TRANSLOCATION; DNA MODIFICATION; EMBRYONIC STEM CELL; EXCISION REPAIR; FLP RECOMBINASE TARGET; GENE CASSETTE; GENE DELETION; GENE EXPRESSION; GENE INSERTION; GENE LOCUS; GENE SILENCING; GENE TARGETING; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOMICS; IN VITRO STUDY; IN VIVO STUDY; INTEGRATION; LENTIVIRINAE; LOXP SITE; MAMMAL CELL; MEDIATOR; MOLECULAR RECOGNITION; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROMOTER REGION; RECOMBINASE MEDIATED CASSETTE EXCHANGE; REVIEW; SITE DIRECTED MUTAGENESIS; YEAST;

ANIMALS; GENE TARGETING; GENOMICS; HUMANS; RECOMBINASES; RECOMBINATION, GENETIC;

IPS; MAMMALIA; PROKARYOTA;

EID: 84872271412     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2012.11.016     Document Type: Review

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