Dual RMCE for efficient re-engineering of mouse mutant alleles

Nature Methods

Volumn 7, Issue 11, 2010, Pages 893-895

  Osterwalder, Marco ^a   Galli, Antonella ^a,c   Rosen, Barry ^b   Skarnes, William C ^b   Zeller, Rolf ^a   Lopez Rios, Javier ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; RECOMBINASE;

ALLELE; ARTICLE; EMBRYONIC STEM CELL; FRT SITE; GENE FREQUENCY; GENE TARGETING; GENETIC ENGINEERING; GLI3 ALLELE; HAND2 ALLELE; LOXP SITE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECOMBINASE MEDIATED CASSETTE EXCHANGE; SEQUENCE TAGGED SITE; SMAD4 ALLELE; ZFP503 ALLELE;

ALLELES; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARRIER PROTEINS; EMBRYONIC STEM CELLS; GENETIC ENGINEERING; MICE; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; RECOMBINASES; RECOMBINATION, GENETIC; SMAD4 PROTEIN;

EID: 78049331001     PISSN: 15487091     EISSN: 15491676     Source Type: Journal    
DOI: 10.1038/nmeth.1521     Document Type: Article

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