Novel Tag-and-Exchange (RMCE) Strategies Generate Master Cell Clones with Predictable and Stable Transgene Expression Properties

Journal of Molecular Biology

Volumn 390, Issue 4, 2009, Pages 579-594

  Qiao, Junhua ^a   Oumard, André ^a   Wegloehner, Wolfgang ^b   Bode, Juergen ^a,c  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b InVivo Biotech Services GmbH   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

gene expression; RMCE; site specific recombination; tag and exchange; targeted integration

Indexed keywords

BUTYRIC ACID; ENHANCED GREEN FLUORESCENT PROTEIN; GANCICLOVIR; HISTONE DEACETYLASE INHIBITOR; HYGROMYCIN B; PHOSPHOTRANSFERASE; RECOMBINASE; THYMIDINE KINASE; TRICHOSTATIN A; VALPROIC ACID;

ANIMAL CELL; ARTICLE; CELL CLONE; CELL CLONING; CELL LINE; CHO CELL; CONTROLLED STUDY; DNA MODIFICATION; DRUG RESEARCH; DRUG SENSITIVITY; EMBRYONIC STEM CELL; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE CASSETTE; GENE EXPRESSION; GENETIC SELECTION; GENOTYPE; NONHUMAN; PLURIPOTENT STEM CELL; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; PROKARYOTE; PROMOTER REGION; TRANSGENE;

CRICETULUS GRISEUS; PROKARYOTA;

EID: 67649321244     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.05.012     Document Type: Article

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