-
1
-
-
0019811465
-
Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences
-
Banerji J, Rusconi S, Schaffner W.1981. Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences. Cell 27:299-308.
-
(1981)
Cell
, vol.27
, pp. 299-308
-
-
Banerji, J.1
Rusconi, S.2
Schaffner, W.3
-
2
-
-
32344453096
-
Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells
-
Beard C, Hochedlinger K, Plath K, Wutz A, Jaenisch R.2006. Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis 44:23-28.
-
(2006)
Genesis
, vol.44
, pp. 23-28
-
-
Beard, C.1
Hochedlinger, K.2
Plath, K.3
Wutz, A.4
Jaenisch, R.5
-
4
-
-
0033560895
-
Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
-
Briscoe J, Sussel L, Serup P, Hartigan-O'Connor D, Jessell TM, Rubenstein JL, Ericson J.1999. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature 398: 622-627.
-
(1999)
Nature
, vol.398
, pp. 622-627
-
-
Briscoe, J.1
Sussel, L.2
Serup, P.3
Hartigan-O'Connor, D.4
Jessell, T.M.5
Rubenstein, J.L.6
Ericson, J.7
-
5
-
-
0037058955
-
The insulation of genes from external enhancers and silencing chromatin
-
Burgess-Beusse B, Farrell C, Gaszner M, Litt M, Mutskov V, Recillas-Targa F, Simpson M, West A, Felsenfeld G.2002. The insulation of genes from external enhancers and silencing chromatin. Proc Natl Acad Sci U S A 99(Suppl 4):16433-16437.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.SUPPL. 4
, pp. 16433-16437
-
-
Burgess-Beusse, B.1
Farrell, C.2
Gaszner, M.3
Litt, M.4
Mutskov, V.5
Recillas-Targa, F.6
Simpson, M.7
West, A.8
Felsenfeld, G.9
-
6
-
-
0024564718
-
The new mouse genetics: Altering the genome by gene targeting
-
Capecchi MR.1989. The new mouse genetics: Altering the genome by gene targeting. Trends Genet 5: 70-76.
-
(1989)
Trends Genet
, vol.5
, pp. 70-76
-
-
Capecchi, M.R.1
-
7
-
-
0037195074
-
Small molecule modulation of Smoothened activity
-
Chen JK, Taipale J, Young KE, Maiti T, Beachy PA.2002. Small molecule modulation of Smoothened activity. Proc Natl Acad Sci U S A 99:14071-14076.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 14071-14076
-
-
Chen, J.K.1
Taipale, J.2
Young, K.E.3
Maiti, T.4
Beachy, P.A.5
-
9
-
-
0035933198
-
Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation
-
Eggan K, Akutsu H, Loring J, Jackson-Grusby L, Klemm M, Rideout WM, III, Yanagimachi R, Jaenisch R.2001. Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation. Proc Natl Acad Sci U S A 98:6209-6214.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6209-6214
-
-
Eggan, K.1
Akutsu, H.2
Loring, J.3
Jackson-Grusby, L.4
Klemm, M.5
Rideout III, W.M.6
Yanagimachi, R.7
Jaenisch, R.8
-
11
-
-
0003799070
-
-
Hogan B, Beddington R, Costantini F, Lacey E, editors., 2nd ed. Cold Spring Harbor:Cold Spring Harbor Laboratory Press.
-
Hogan B, Beddington R, Costantini F, Lacey E, editors.1994. Manipulating the mouse embryo: A laboratory manual, 2nd ed. Cold Spring Harbor:Cold Spring Harbor Laboratory Press.
-
(1994)
Manipulating the mouse embryo: A laboratory manual
-
-
-
12
-
-
68549128962
-
Directed differentiation of pluripotent stem cells: from developmental biology to therapeutic applications
-
Irion S, Nostro MC, Kattman SJ, Keller GM.2008. Directed differentiation of pluripotent stem cells: from developmental biology to therapeutic applications. Cold Spring Harb Symp Quant Biol 73: 101-110.
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 101-110
-
-
Irion, S.1
Nostro, M.C.2
Kattman, S.J.3
Keller, G.M.4
-
13
-
-
18844396119
-
Embryonic stem cell differentiation: emergence of a new era in biology and medicine
-
Keller G.2005. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev 19:1129-1155.
-
(2005)
Genes Dev
, vol.19
, pp. 1129-1155
-
-
Keller, G.1
-
14
-
-
33747833061
-
Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube
-
Lei Q, Jeong Y, Misra K, Li S, Zelman AK, Epstein DJ, Matise MP.2006. Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube. Dev Cell 11: 325-337.
-
(2006)
Dev Cell
, vol.11
, pp. 325-337
-
-
Lei, Q.1
Jeong, Y.2
Misra, K.3
Li, S.4
Zelman, A.K.5
Epstein, D.J.6
Matise, M.P.7
-
15
-
-
39049135380
-
Genomic identification of regulatory elements by evolutionary sequence comparison and functional analysis
-
Loots GG.2008. Genomic identification of regulatory elements by evolutionary sequence comparison and functional analysis. Adv Genet 61:269-293.
-
(2008)
Adv Genet
, vol.61
, pp. 269-293
-
-
Loots, G.G.1
-
16
-
-
28544434189
-
An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo
-
Mao J, Barrow J, McMahon J, Vaughan J, McMahon AP.2005. An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo. Nucleic Acids Res 33:e155.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Mao, J.1
Barrow, J.2
McMahon, J.3
Vaughan, J.4
McMahon, A.P.5
-
17
-
-
0036333208
-
A mitogen gradient of dorsal midline Wnts organizes growth in the CNS
-
Megason SG, McMahon AP.2002.A mitogen gradient of dorsal midline Wnts organizes growth in the CNS. Development 129:2087-2098.
-
(2002)
Development
, vol.129
, pp. 2087-2098
-
-
Megason, S.G.1
McMahon, A.P.2
-
18
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J.2011.A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470:279-283.
-
(2011)
Nature
, vol.470
, pp. 279-283
-
-
Rada-Iglesias, A.1
Bajpai, R.2
Swigut, T.3
Brugmann, S.A.4
Flynn, R.A.5
Wysocka, J.6
-
19
-
-
33947647023
-
High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells
-
Raymond CS, Soriano P.2007. High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells. PLoS ONE 2:e162.
-
(2007)
PLoS ONE
, vol.2
-
-
Raymond, C.S.1
Soriano, P.2
-
20
-
-
0031034460
-
Double-reciprocal crossover mediated by FLP-recombinase: a concept and an assay
-
Seibler J, Bode J.1997. Double-reciprocal crossover mediated by FLP-recombinase: a concept and an assay. Biochemistry 36:1740-1747.
-
(1997)
Biochemistry
, vol.36
, pp. 1740-1747
-
-
Seibler, J.1
Bode, J.2
-
21
-
-
26644467465
-
Single copy shRNA configuration for ubiquitous gene knockdown in mice
-
Seibler J, Kuter-Luks B, Kern H, Streu S, Plum L, Mauer J, Kuhn R, Bruning JC, Schwenk F.2005. Single copy shRNA configuration for ubiquitous gene knockdown in mice. Nucleic Acids Res 33:e67.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Seibler, J.1
Kuter-Luks, B.2
Kern, H.3
Streu, S.4
Plum, L.5
Mauer, J.6
Kuhn, R.7
Bruning, J.C.8
Schwenk, F.9
-
22
-
-
3042856262
-
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
-
Srinivas S, Watanabe T, Lin CS, William CM, Tanabe Y, Jessell TM, Costantini F.2001. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol 1:4.
-
(2001)
BMC Dev Biol
, vol.1
, pp. 4
-
-
Srinivas, S.1
Watanabe, T.2
Lin, C.S.3
William, C.M.4
Tanabe, Y.5
Jessell, T.M.6
Costantini, F.7
-
23
-
-
0029935327
-
Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes
-
Tucker KL, Beard C, Dausmann J, Jackson-Grusby L, Laird PW, Lei H, Li E, Jaenisch R.1996. Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes. Genes Dev 10:1008-1020.
-
(1996)
Genes Dev
, vol.10
, pp. 1008-1020
-
-
Tucker, K.L.1
Beard, C.2
Dausmann, J.3
Jackson-Grusby, L.4
Laird, P.W.5
Lei, H.6
Li, E.7
Jaenisch, R.8
-
24
-
-
79952310557
-
Recombinase-mediated cassette exchange (RMCE): Traditional concepts and current challenges
-
Turan S, Galla M, Ernst E, Qiao J, Voelkel C, Schiedlmeier B, Zehe C, Bode J.2011. Recombinase-mediated cassette exchange (RMCE): Traditional concepts and current challenges.J Mol Biol 407:193-221.
-
(2011)
J Mol Biol
, vol.407
, pp. 193-221
-
-
Turan, S.1
Galla, M.2
Ernst, E.3
Qiao, J.4
Voelkel, C.5
Schiedlmeier, B.6
Zehe, C.7
Bode, J.8
-
25
-
-
60149091656
-
ChIP-seq accurately predicts tissue-specific activity of enhancers
-
Visel A, Blow MJ, Li Z, Zhang T, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Wright C, Chen F, Afzal V, Ren B, Rubin EM, Pennacchio LA.2009a. ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 457:854-858.
-
(2009)
Nature
, vol.457
, pp. 854-858
-
-
Visel, A.1
Blow, M.J.2
Li, Z.3
Zhang, T.4
Akiyama, J.A.5
Holt, A.6
Plajzer-Frick, I.7
Shoukry, M.8
Wright, C.9
Chen, F.10
Afzal, V.11
Ren, B.12
Rubin, E.M.13
Pennacchio, L.A.14
-
26
-
-
70249088327
-
Genomic views of distant-acting enhancers
-
Visel A, Rubin EM, Pennacchio LA.2009b. Genomic views of distant-acting enhancers. Nature 461:199-205.
-
(2009)
Nature
, vol.461
, pp. 199-205
-
-
Visel, A.1
Rubin, E.M.2
Pennacchio, L.A.3
-
27
-
-
34250612602
-
Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning
-
Vokes SA, Ji H, McCuine S, Tenzen T, Giles S, Zhong S, Longabaugh WJ, Davidson EH, Wong WH, McMahon AP.2007. Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning. Development 134:1977-1989.
-
(2007)
Development
, vol.134
, pp. 1977-1989
-
-
Vokes, S.A.1
Ji, H.2
McCuine, S.3
Tenzen, T.4
Giles, S.5
Zhong, S.6
Longabaugh, W.J.7
Davidson, E.H.8
Wong, W.H.9
McMahon, A.P.10
-
28
-
-
38049177362
-
Site-directed, virus-free, and inducible RNAi in embryonic stem cells
-
Wang J, Theunissen TW, Orkin SH.2007. Site-directed, virus-free, and inducible RNAi in embryonic stem cells. Proc Natl Acad Sci U S A 104:20850-20855.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20850-20855
-
-
Wang, J.1
Theunissen, T.W.2
Orkin, S.H.3
-
29
-
-
0037047320
-
Directed differentiation of embryonic stem cells into motor neurons
-
Wichterle H, Lieberam I, Porter JA, Jessell TM.2002. Directed differentiation of embryonic stem cells into motor neurons. Cell 110:385-397.
-
(2002)
Cell
, vol.110
, pp. 385-397
-
-
Wichterle, H.1
Lieberam, I.2
Porter, J.A.3
Jessell, T.M.4
-
31
-
-
0030990991
-
Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells
-
Zambrowicz BP, Imamoto A, Fiering S, Herzenberg LA, Kerr WG, Soriano P.1997. Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci U S A 94:3789-3794.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 3789-3794
-
-
Zambrowicz, B.P.1
Imamoto, A.2
Fiering, S.3
Herzenberg, L.A.4
Kerr, W.G.5
Soriano, P.6
-
32
-
-
55049098278
-
Embryonic stem cells as a platform for analyzing neural gene transcription
-
Zhang X, Horrell SA, Delaney D, Gottlieb DI.2008. Embryonic stem cells as a platform for analyzing neural gene transcription. Stem Cells 26:1841-1849.
-
(2008)
Stem Cells
, vol.26
, pp. 1841-1849
-
-
Zhang, X.1
Horrell, S.A.2
Delaney, D.3
Gottlieb, D.I.4
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