-
1
-
-
0028148244
-
Site-specific recombination: Developments and applications
-
Sauer, B. 1994. Site-specific recombination: developments and applications. Curr. Opin. Biotechnol. 5:521-527.
-
(1994)
Curr. Opin. Biotechnol.
, vol.5
, pp. 521-527
-
-
Sauer, B.1
-
2
-
-
0029316784
-
Genome engineering: The new mouse genetics
-
Rossant, J. and Nagy, A. 1995. Genome engineering: the new mouse genetics. Nat. Med. 1:592-594.
-
(1995)
Nat. Med.
, vol.1
, pp. 592-594
-
-
Rossant, J.1
Nagy, A.2
-
3
-
-
0029959207
-
Conditional gene targeting
-
Rajewsky, K., Gu, H., Kühn, R., Betz, U.A., Muller, W., Roes, J., and Schwenk, F. 1996. Conditional gene targeting. J. Clin. Invest. 98:600-603.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 600-603
-
-
Rajewsky, K.1
Gu, H.2
Kühn, R.3
Betz, U.A.4
Muller, W.5
Roes, J.6
Schwenk, F.7
-
4
-
-
0027422291
-
Site-specific recombinases: Tools for genome engineering
-
Kilby, N.J., Snaith, M.R., and Murray, J.A. 1993. Site-specific recombinases: tools for genome engineering. Trends Genet. 9:413-421.
-
(1993)
Trends Genet.
, vol.9
, pp. 413-421
-
-
Kilby, N.J.1
Snaith, M.R.2
Murray, J.A.3
-
5
-
-
0028950996
-
A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination
-
Smith, A.J., De Sousa, M.A., Kwabi-Addo, B., Heppell-Parton, A., Impey, H., and Rabbitts, P. 1995. A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination. Nat. Genet. 9:376-385.
-
(1995)
Nat. Genet.
, vol.9
, pp. 376-385
-
-
Smith, A.J.1
De Sousa, M.A.2
Kwabi-Addo, B.3
Heppell-Parton, A.4
Impey, H.5
Rabbitts, P.6
-
6
-
-
0029562967
-
Chromosome engineering in mice
-
Ramirez Solis, R., Liu, P., and Bradley, A. 1995. Chromosome engineering in mice. Nature 378:720-724.
-
(1995)
Nature
, vol.378
, pp. 720-724
-
-
Ramirez Solis, R.1
Liu, P.2
Bradley, A.3
-
7
-
-
0028059099
-
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
-
Gu, H., Marth, J.D., Orban, P.C., Mossmann, H., and Rajewsky, K. 1994. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 265:103-106.
-
(1994)
Science
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
8
-
-
2642625666
-
Temporally and spatially regulated somatic mutagenesis in mice
-
Schwenk, F., Kühn, R., Angrand, P.O., Rajewsky, K., and Stewart, A.F. 1998. Temporally and spatially regulated somatic mutagenesis in mice. Nucleic Acids Res. 26:1427-1432.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 1427-1432
-
-
Schwenk, F.1
Kühn, R.2
Angrand, P.O.3
Rajewsky, K.4
Stewart, A.F.5
-
9
-
-
0029043630
-
Ligand-regulated site-specific recombination
-
Logie, C. and Stewart, A.F. 1995. Ligand-regulated site-specific recombination. Proc. Natl. Acad. Sci. USA 92:5940-5944.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5940-5944
-
-
Logie, C.1
Stewart, A.F.2
-
10
-
-
0024378286
-
The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome
-
Golic, K.G. and Lindquist, S. 1989. The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome. Cell 59:499-509.
-
(1989)
Cell
, vol.59
, pp. 499-509
-
-
Golic, K.G.1
Lindquist, S.2
-
11
-
-
0027280936
-
Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP- Mediated gene targeting
-
Gu, H., Zou, Y.R., and Rajewsky, K. 1993. Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73:1155-1164.
-
(1993)
Cell
, vol.73
, pp. 1155-1164
-
-
Gu, H.1
Zou, Y.R.2
Rajewsky, K.3
-
12
-
-
0031916557
-
An Fgf8 mutant allelic series generated by Cre- And FLP-mediated recombination
-
Meyers, E.N., Lewandoski, M., and Martin, G.R. 1998. An Fgf8 mutant allelic series generated by Cre-and FLP-mediated recombination. Nat. Gen. 18:136-141.
-
(1998)
Nat. Gen.
, vol.18
, pp. 136-141
-
-
Meyers, E.N.1
Lewandoski, M.2
Martin, G.R.3
-
13
-
-
0029860719
-
Different thermostabilities of FLP and Cre recombinases: Implications for applied site-specific recombination
-
Buchholz, F., Ringrose, L., Angrand, P.O., Rossi, F., and Stewart, A.F. 1996. Different thermostabilities of FLP and Cre recombinases: implications for applied site-specific recombination. Nucleic Acids Res. 24:4256-4262.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 4256-4262
-
-
Buchholz, F.1
Ringrose, L.2
Angrand, P.O.3
Rossi, F.4
Stewart, A.F.5
-
14
-
-
0028999244
-
Biotechnology: Making selection work
-
Brookfield, J.F. 1995. Biotechnology: making selection work. Nature 375:449.
-
(1995)
Nature
, vol.375
, pp. 449
-
-
Brookfield, J.F.1
-
15
-
-
0029670577
-
Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents
-
Moore, J.C. and Arnold, H.A. 1996. Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents. Nature Biotechnology 14:458-467.
-
(1996)
Nature Biotechnology
, vol.14
, pp. 458-467
-
-
Moore, J.C.1
Arnold, H.A.2
-
16
-
-
0029670330
-
Improved green fluorescent protein by molecular evolution using DNA shuffling
-
Crameri, A., Whitehorn, E.A., Tate, E., and Stemmer, W.P.C. 1996. Improved green fluorescent protein by molecular evolution using DNA shuffling. Nature Biotechnology 14:315-319.
-
(1996)
Nature Biotechnology
, vol.14
, pp. 315-319
-
-
Crameri, A.1
Whitehorn, E.A.2
Tate, E.3
Stemmer, W.P.C.4
-
17
-
-
0031543435
-
Directed evolution of enzyme catalysts
-
Kuchner, O. and Arnold, F.H. 1997. Directed evolution of enzyme catalysts. Trends in Biotechnology 15:523-530.
-
(1997)
Trends in Biotechnology
, vol.15
, pp. 523-530
-
-
Kuchner, O.1
Arnold, F.H.2
-
18
-
-
0028050350
-
Rapid evolution of a protein in vitro by DNA shuffling
-
Stemmer, W.P. 1994. Rapid evolution of a protein in vitro by DNA shuffling. Nature 370:389-391.
-
(1994)
Nature
, vol.370
, pp. 389-391
-
-
Stemmer, W.P.1
-
19
-
-
0023475850
-
Curing of endogenous 2 micron DNA in yeast by recombinant vectors
-
Harford, M.N. and Peeters, M. 1987. Curing of endogenous 2 micron DNA in yeast by recombinant vectors. Curr. Genet. 11:315-319.
-
(1987)
Curr. Genet.
, vol.11
, pp. 315-319
-
-
Harford, M.N.1
Peeters, M.2
-
20
-
-
0029018327
-
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter
-
Guzman, L.M., Belin, D., Carson, M.J., and Beckwith, J. 1995. Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter. J. Bacteriol. 177:4121-4130.
-
(1995)
J. Bacteriol.
, vol.177
, pp. 4121-4130
-
-
Guzman, L.M.1
Belin, D.2
Carson, M.J.3
Beckwith, J.4
-
21
-
-
0023841525
-
Mutations that improve the binding of yeast FLP recombinase to its substrate
-
Lebreton, B., Prasad, P.V., Jayaram, M., and Youderian, P. 1988. Mutations that improve the binding of yeast FLP recombinase to its substrate. Genetics 118:393-400.
-
(1988)
Genetics
, vol.118
, pp. 393-400
-
-
Lebreton, B.1
Prasad, P.V.2
Jayaram, M.3
Youderian, P.4
-
22
-
-
0022669622
-
The integrase family of site-specific recombinases: Regional similarities and global diversity
-
Argos, P., Landy, A., Abremski, K., Egan, J.B., Haggard-Ljungquist, E., Hoess, R.H. et al. 1986. The integrase family of site-specific recombinases: regional similarities and global diversity. EMBO J. 5:433-440.
-
(1986)
EMBO J.
, vol.5
, pp. 433-440
-
-
Argos, P.1
Landy, A.2
Abremski, K.3
Egan, J.B.4
Haggard-Ljungquist, E.5
Hoess, R.H.6
-
23
-
-
0038659759
-
Similarities and differences among 105 members of the Int family of site-specific recombinases
-
Nunes-Duby, S.E., Kwon, H.J., Tirumalai, R.S., Ellenberger, T., and Landy, A. 1998. Similarities and differences among 105 members of the Int family of site-specific recombinases. Nucleic Acids Res 26:391-406.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 391-406
-
-
Nunes-Duby, S.E.1
Kwon, H.J.2
Tirumalai, R.S.3
Ellenberger, T.4
Landy, A.5
-
24
-
-
0001656001
-
Flexibility in DNA recombination: Structure of the lambda integrase catalytic core
-
Kwon, H.J., Tirumalai, R., Landy, A., and Ellenberger, T. 1997. Flexibility in DNA recombination: structure of the lambda integrase catalytic core. Science 276:126-131.
-
(1997)
Science
, vol.276
, pp. 126-131
-
-
Kwon, H.J.1
Tirumalai, R.2
Landy, A.3
Ellenberger, T.4
-
25
-
-
0030904786
-
Molecular organization in site-specific recombination: The catalytic domain of bacteriophage HP1 integrase at 2.7 Å resolution
-
Hickman, A.B., Waninger, S., Scocca, J.J., and Dyda, F. 1997. Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 Å resolution. Cell 89:227-237.
-
(1997)
Cell
, vol.89
, pp. 227-237
-
-
Hickman, A.B.1
Waninger, S.2
Scocca, J.J.3
Dyda, F.4
-
26
-
-
0030886293
-
Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse
-
Quo, F., Gopaul, D.N., and Van Duyne, G.D. 1997. Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse. Nature 389:40.
-
(1997)
Nature
, vol.389
, pp. 40
-
-
Quo, F.1
Gopaul, D.N.2
Van Duyne, G.D.3
-
27
-
-
0030817595
-
Crystal structure of the site-specific recombinase, XerD
-
Subramanya, H.S., Arciszewska, L.K., Baker, R.A., Bird, L.E., Sherratt, D.J., and Wigley, D.B. 1997. Crystal structure of the site-specific recombinase, XerD. EMBO J. 16:5178-5187.
-
(1997)
EMBO J.
, vol.16
, pp. 5178-5187
-
-
Subramanya, H.S.1
Arciszewska, L.K.2
Baker, R.A.3
Bird, L.E.4
Sherratt, D.J.5
Wigley, D.B.6
-
28
-
-
0023508147
-
Yeast plasmids resembling 2 micron DNA: Regional similarities and diversities at the molecular level
-
Utatsu, I., Sakamoto, S., Imura, T., and Tohe, A. 1987. Yeast plasmids resembling 2 micron DNA: regional similarities and diversities at the molecular level. J. Bacteriol. 169:5537-5545.
-
(1987)
J. Bacteriol.
, vol.169
, pp. 5537-5545
-
-
Utatsu, I.1
Sakamoto, S.2
Imura, T.3
Tohe, A.4
-
29
-
-
0025129866
-
Identification of the active site tyrosine of Flp recombinase. Possible relevance of its location to the mechanism of recombination
-
published erratum appears in J. Biol. Chem. 266:7312, 1991
-
Evans, B.R., Chen, J.W., Parsons, R.L., Bauer, T.K., Teplow, D.B., and Jayaram, M. 1990. Identification of the active site tyrosine of Flp recombinase. Possible relevance of its location to the mechanism of recombination. J. Biol. Chem. 265:18504-18510. [published erratum appears in J. Biol. Chem. 266:7312, 1991.]
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 18504-18510
-
-
Evans, B.R.1
Chen, J.W.2
Parsons, R.L.3
Bauer, T.K.4
Teplow, D.B.5
Jayaram, M.6
-
30
-
-
0026316101
-
The N-end rule in bacteria
-
Tobias, J.W., Shrader, T.E., Rocap, G., and Varshavsky, A. 1991. The N-end rule in bacteria. Science 254:1374-1377.
-
(1991)
Science
, vol.254
, pp. 1374-1377
-
-
Tobias, J.W.1
Shrader, T.E.2
Rocap, G.3
Varshavsky, A.4
-
31
-
-
0025848032
-
Identification of the DNA-binding domain of the FLP recombinase
-
Pan, H., Clary, D., and Sadowski, P.D. 1991. Identification of the DNA-binding domain of the FLP recombinase. J. Biol. Chem. 266:11347-11354.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 11347-11354
-
-
Pan, H.1
Clary, D.2
Sadowski, P.D.3
-
32
-
-
0029893110
-
Thermozymes: Identifying molecular determinants of protein structure and functional stability
-
Vieille, C. and Zeikus, J.G. 1996. Thermozymes: identifying molecular determinants of protein structure and functional stability. Trends in Biotechnology 14:183-190.
-
(1996)
Trends in Biotechnology
, vol.14
, pp. 183-190
-
-
Vieille, C.1
Zeikus, J.G.2
-
33
-
-
0026316725
-
Proline residues responsible for thermostability occur with high frequency in the loop regions of an extremely thermostable oligo-1,6-glucosidase from Bacillus thermoglucosidasius KP1006
-
Watanabe, K., Chishiro, K., Kitamura, K., and Suzuki, Y. 1991. Proline residues responsible for thermostability occur with high frequency in the loop regions of an extremely thermostable oligo-1,6-glucosidase from Bacillus thermoglucosidasius KP1006. J. Biol. Chem. 266:24287-24294.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 24287-24294
-
-
Watanabe, K.1
Chishiro, K.2
Kitamura, K.3
Suzuki, Y.4
-
34
-
-
0029950256
-
Cloning and expression of the gene encoding the Thermoanaerobacter ethanolicus 39E secondary-alcohol dehydrogenase and biochemical characterization of the enzyme
-
Burdette, D.S., Vieille, C., and Zeikus, J.G. 1996. Cloning and expression of the gene encoding the Thermoanaerobacter ethanolicus 39E secondary-alcohol dehydrogenase and biochemical characterization of the enzyme. Biochem. J. 316:115-122.
-
(1996)
Biochem. J.
, vol.316
, pp. 115-122
-
-
Burdette, D.S.1
Vieille, C.2
Zeikus, J.G.3
-
35
-
-
0023664818
-
Purification of the FLP site-specific recombinase by affinity chromatography and re-examination of basic properties of the system
-
Meyer-Leon, L., Gates, C.A., Attwood, J.M., Wood, E.A., and Cox, M.M. 1987. Purification of the FLP site-specific recombinase by affinity chromatography and re-examination of basic properties of the system. Nucleic Acids Res. 15:6469-6488.
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 6469-6488
-
-
Meyer-Leon, L.1
Gates, C.A.2
Attwood, J.M.3
Wood, E.A.4
Cox, M.M.5
-
36
-
-
0030771423
-
The mouse that prompted a roar
-
Marshall, E. 1997. The mouse that prompted a roar. Science 277:24-25.
-
(1997)
Science
, vol.277
, pp. 24-25
-
-
Marshall, E.1
-
37
-
-
84920317433
-
Mouse engineering
-
19997
-
O'Gorman, S. and Wahl, G.M. 19997. Mouse engineering. Science 277:1116-1117.
-
Science
, vol.277
, pp. 1116-1117
-
-
O'Gorman, S.1
Wahl, G.M.2
-
38
-
-
0024850487
-
Cloning, characterization and heterologous expression of the Smal restriction-modification system
-
Heidmann, S., Seifert, W., Kessler, C., and Domdey, H. 1989. Cloning, characterization and heterologous expression of the Smal restriction-modification system. Nucleic Acids Res. 17:9783-9796.
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 9783-9796
-
-
Heidmann, S.1
Seifert, W.2
Kessler, C.3
Domdey, H.4
-
39
-
-
0029739282
-
A simple assay to determine the functionality of Cre or FLP recombination targets in genomic manipulation constructs
-
Buchholz, F., Angrand, P.-O., and Stewart, A.F. 1996. A simple assay to determine the functionality of Cre or FLP recombination targets in genomic manipulation constructs. Nucleic Acids Res. 24:3118-3119.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 3118-3119
-
-
Buchholz, F.1
Angrand, P.-O.2
Stewart, A.F.3
-
40
-
-
0028816556
-
Direct random mutagenesis of gene-sized DNA fragments using polymerase chain reaction
-
Fromant, M., Blanquet, S., and Plateau, P. 1995. Direct random mutagenesis of gene-sized DNA fragments using polymerase chain reaction. Anal. Biochem. 224:347-353.
-
(1995)
Anal. Biochem.
, vol.224
, pp. 347-353
-
-
Fromant, M.1
Blanquet, S.2
Plateau, P.3
-
41
-
-
0029999325
-
Hypermutagenic PCR involving all four transitions and a sizeable proportion of transversions
-
Vartanian, J.P., Henry, M., and Wain Hobson, S. 1996. Hypermutagenic PCR involving all four transitions and a sizeable proportion of transversions. Nucleic Acids Res. 24:2627-2631.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 2627-2631
-
-
Vartanian, J.P.1
Henry, M.2
Wain Hobson, S.3
-
43
-
-
0023660545
-
A mutational analysis of the bacteriophage P1 recombinase Cre
-
Wierzbicki, A., Kendall, M., Abremski, K., and Hoess, R. 1987. A mutational analysis of the bacteriophage P1 recombinase Cre. J. Mol. Biol. 195:785-794.
-
(1987)
J. Mol. Biol.
, vol.195
, pp. 785-794
-
-
Wierzbicki, A.1
Kendall, M.2
Abremski, K.3
Hoess, R.4
-
44
-
-
0027321548
-
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells
-
Nagy, A., Rossant, J., Nagy, R., Abramow Newerly, W., and Roder, J.C. 1993. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90:8424-8428.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8424-8428
-
-
Nagy, A.1
Rossant, J.2
Nagy, R.3
Abramow Newerly, W.4
Roder, J.C.5
-
45
-
-
0029874029
-
Regulation of Cre recombinase activity by the synthetic steroid RU 486
-
Kellendonk, C., Tronche, F., Monaghan, A.P., Angrand, P.O., Stweart, A.F., and Schütz, G. 1996. Regulation of Cre recombinase activity by the synthetic steroid RU 486. Nucleic Acids Res. 24:1404-1411.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 1404-1411
-
-
Kellendonk, C.1
Tronche, F.2
Monaghan, A.P.3
Angrand, P.O.4
Stweart, A.F.5
Schütz, G.6
-
46
-
-
0028158628
-
PHD - An automatic mail server for protein secondary structure prediction
-
Rost, B., Sander, C., and Schneider, R. 1994. PHD - an automatic mail server for protein secondary structure prediction. Comput. Appl. Biosci. 10:53-60.
-
(1994)
Comput. Appl. Biosci.
, vol.10
, pp. 53-60
-
-
Rost, B.1
Sander, C.2
Schneider, R.3
|