PGC1α and mitochondrial metabolism - emerging concepts and relevance in ageing and neurodegenerative disorders

Journal of Cell Science

Volumn 125, Issue 21, 2012, Pages 4963-4971

  Austin, Shane ^a   St Pierre, Julie ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Ageing; Mitochondrial biogenesis; Mitochondrial remodelling; Neurodegeneration; PGC1 ; Reactive oxygen species (ROS)

Indexed keywords

MITOCHONDRIAL DNA; MITOGEN ACTIVATED PROTEIN KINASE 14; NUCLEAR RESPIRATORY FACTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE B; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; SIRTUIN 1; UNCOUPLING PROTEIN 1;

ACETYLATION; ADIPOCYTE; AEROBIC METABOLISM; AGING; BIOGENESIS; CELL FUNCTION; CELL ORGANELLE; CYTOPLASM; DEACETYLATION; DNA REPLICATION; ELECTRON SPIN RESONANCE; ELECTRON TRANSPORT; ENZYME PHOSPHORYLATION; FLUOROMETRY; GENE EXPRESSION; HUMAN; METHYLATION; MITOCHONDRIAL RESPIRATION; NERVE DEGENERATION; NONHUMAN; NOTE; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SUMOYLATION;

EID: 84872225149     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.113662     Document Type: Note

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