메뉴 건너뛰기




Volumn 435, Issue 2, 2011, Pages 297-312

Assessing mitochondrial dysfunction in cells

Author keywords

Membrane potential; Mitochondrial function; Mitochondrion; Respiration; Respiratory control

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOCHROME C OXIDASE; PROTON; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); TRICARBOXYLIC ACID;

EID: 79953180902     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20110162     Document Type: Review
Times cited : (1872)

References (107)
  • 1
    • 78149366638 scopus 로고    scopus 로고
    • Sepsis and septic shock: Pathophysiological and cardiovascular background as basis for therapy
    • De Kock, I., Van Daele, C. and Poelaert, J. (2010) Sepsis and septic shock: pathophysiological and cardiovascular background as basis for therapy. Acta Clin. Belg. 65, 323-329
    • (2010) Acta Clin. Belg. , vol.65 , pp. 323-329
    • De Kock, I.1    Van Daele, C.2    Poelaert, J.3
  • 4
    • 77956249894 scopus 로고    scopus 로고
    • Autism and mitochondrial disease
    • Haas, R. H. (2010) Autism and mitochondrial disease. Dev. Disabil. Res. Rev. 16, 144-153
    • (2010) Dev. Disabil. Res. Rev. , vol.16 , pp. 144-153
    • Haas, R.H.1
  • 5
    • 77956571785 scopus 로고    scopus 로고
    • The importance of mitochondria in age-related and inherited eye disorders
    • Jarrett, S. G., Lewin, A. S. and Boulton, M. E. (2010) The importance of mitochondria in age-related and inherited eye disorders. Ophthalmic Res. 44, 179-190
    • (2010) Ophthalmic Res. , vol.44 , pp. 179-190
    • Jarrett, S.G.1    Lewin, A.S.2    Boulton, M.E.3
  • 6
    • 77956183828 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and intracellular calcium dysregulation in ALS
    • Kawamata, H. and Manfredi, G. (2010) Mitochondrial dysfunction and intracellular calcium dysregulation in ALS. Mech. Ageing Dev. 131, 517-526
    • (2010) Mech. Ageing Dev. , vol.131 , pp. 517-526
    • Kawamata, H.1    Manfredi, G.2
  • 7
    • 78649286558 scopus 로고    scopus 로고
    • Parkinson's disease: Mitochondrial molecular pathology, inflammation, statins, and therapeutic neuroprotective nutrition
    • Kones, R. (2010) Parkinson's disease: mitochondrial molecular pathology, inflammation, statins, and therapeutic neuroprotective nutrition. Nutr. Clin. Pract. 25, 371-389
    • (2010) Nutr. Clin. Pract. , vol.25 , pp. 371-389
    • Kones, R.1
  • 8
    • 78149409465 scopus 로고    scopus 로고
    • Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease
    • Ren, J., Pulakat, L., Whaley-Connell, A. and Sowers, J. R. (2010) Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease. J. Mol. Med. 88, 993-1001
    • (2010) J. Mol. Med. , vol.88 , pp. 993-1001
    • Ren, J.1    Pulakat, L.2    Whaley-Connell, A.3    Sowers, J.R.4
  • 9
    • 78650656839 scopus 로고    scopus 로고
    • Oxidative stress and endothelial dysfunction in cardiovascular disease: Mitochondria-targeted therapeutics
    • Rocha, M., Apostolova, N., Hernandez-Mijares, A., Herance, R. and Victor, V. M. (2010) Oxidative stress and endothelial dysfunction in cardiovascular disease: mitochondria-targeted therapeutics. Curr. Med. Chem. 17, 3827-3841
    • (2010) Curr. Med. Chem. , vol.17 , pp. 3827-3841
    • Rocha, M.1    Apostolova, N.2    Hernandez-Mijares, A.3    Herance, R.4    Victor, V.M.5
  • 10
    • 77957993152 scopus 로고    scopus 로고
    • Mitochondrial-associated metabolic changes and neurodegeneration in Huntington's disease - From clinical features to the bench
    • Rosenstock, T. R., Duarte, A. I. and Rego, A. C. (2010) Mitochondrial-associated metabolic changes and neurodegeneration in Huntington's disease - from clinical features to the bench. Curr. Drug Targets 11, 1218-1236
    • (2010) Curr. Drug Targets , vol.11 , pp. 1218-1236
    • Rosenstock, T.R.1    Duarte, A.I.2    Rego, A.C.3
  • 11
    • 78649510476 scopus 로고    scopus 로고
    • Dementia, stroke and migraine - Some common pathological mechanisms
    • Sas, K., Pardutz, A., Toldi, J. and Vecsei, L. (2010) Dementia, stroke and migraine - some common pathological mechanisms. J. Neurol. Sci. 299, 55-65
    • (2010) J. Neurol. Sci. , vol.299 , pp. 55-65
    • Sas, K.1    Pardutz, A.2    Toldi, J.3    Vecsei, L.4
  • 12
    • 77956236965 scopus 로고    scopus 로고
    • The role of mitochondrial dysfunction in psychiatric disease
    • Scaglia, F. (2010) The role of mitochondrial dysfunction in psychiatric disease. Dev. Disabil. Res. Rev. 16, 136-143
    • (2010) Dev. Disabil. Res. Rev. , vol.16 , pp. 136-143
    • Scaglia, F.1
  • 13
    • 78751648925 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress: A contributing link to acquired epilepsy?
    • Waldbaum, S. and Patel, M. (2010) Mitochondrial dysfunction and oxidative stress: a contributing link to acquired epilepsy? J. Bioenerg. Biomembr. 42, 449-455
    • (2010) J. Bioenerg. Biomembr. , vol.42 , pp. 449-455
    • Waldbaum, S.1    Patel, M.2
  • 14
    • 54349127397 scopus 로고    scopus 로고
    • Effect of the multitargeted tyrosine kinase inhibitors imatinib, dasatinib, sunitinib, and sorafenib on mitochondrial function in isolated rat heart mitochondria and H9c2 cells
    • Will, Y., Dykens, J. A., Nadanaciva, S., Hirakawa, B., Jamieson, J., Marroquin, L. D., Hynes, J., Patyna, S. and Jessen, B. A. (2008) Effect of the multitargeted tyrosine kinase inhibitors imatinib, dasatinib, sunitinib, and sorafenib on mitochondrial function in isolated rat heart mitochondria and H9c2 cells. Toxicol. Sci. 106, 153-161
    • (2008) Toxicol. Sci. , vol.106 , pp. 153-161
    • Will, Y.1    Dykens, J.A.2    Nadanaciva, S.3    Hirakawa, B.4    Jamieson, J.5    Marroquin, L.D.6    Hynes, J.7    Patyna, S.8    Jessen, B.A.9
  • 16
    • 27844484309 scopus 로고    scopus 로고
    • The efficiency and plasticity of mitochondrial energy transduction
    • Brand, M. D. (2005) The efficiency and plasticity of mitochondrial energy transduction. Biochem. Soc. Trans. 33, 897-904
    • (2005) Biochem. Soc. Trans. , vol.33 , pp. 897-904
    • Brand, M.D.1
  • 17
    • 11144263646 scopus 로고    scopus 로고
    • P/O ratios of mitochondrial oxidative phosphorylation
    • Hinkle, P. C. (2005) P/O ratios of mitochondrial oxidative phosphorylation. Biochim. Biophys. Acta 1706, 1-11
    • (2005) Biochim. Biophys. Acta , vol.1706 , pp. 1-11
    • Hinkle, P.C.1
  • 18
    • 0014470420 scopus 로고
    • Estimation of membrane potential and pH difference across the cristae membrane of rat liver mitochondria
    • Mitchell, P. and Moyle, J. (1969) Estimation of membrane potential and pH difference across the cristae membrane of rat liver mitochondria. Eur. J. Biochem. 7, 471-484
    • (1969) Eur. J. Biochem. , vol.7 , pp. 471-484
    • Mitchell, P.1    Moyle, J.2
  • 19
    • 0016304940 scopus 로고
    • Hamster brown-adipose-tissue mitochondria. The control of respiration and the proton electrochemical potential gradient by possible physiological effectors of the proton conductance of the inner membrane
    • Nicholls, D. G. (1974) Hamster brown-adipose-tissue mitochondria. The control of respiration and the proton electrochemical potential gradient by possible physiological effectors of the proton conductance of the inner membrane. Eur. J. Biochem. 49, 573-583
    • (1974) Eur. J. Biochem. , vol.49 , pp. 573-583
    • Nicholls, D.G.1
  • 21
    • 0025238864 scopus 로고
    • Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory
    • Hafner, R. P., Brown, G. C. and Brand, M. D. (1990) Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory. Eur. J. Biochem. 188, 313-319
    • (1990) Eur. J. Biochem. , vol.188 , pp. 313-319
    • Hafner, R.P.1    Brown, G.C.2    Brand, M.D.3
  • 22
    • 0017638174 scopus 로고
    • The effective proton conductance of the inner membrane of mitochondria from brown adipose tissue. Dependency on proton electrochemical potential gradient
    • Nicholls, D. G. (1977) The effective proton conductance of the inner membrane of mitochondria from brown adipose tissue. Dependency on proton electrochemical potential gradient. Eur. J. Biochem. 77, 349-356
    • (1977) Eur. J. Biochem. , vol.77 , pp. 349-356
    • Nicholls, D.G.1
  • 23
    • 0025359843 scopus 로고
    • Non-ohmic proton conductance of the mitochondrial inner membrane in hepatocytes
    • Nobes, C. D., Brown, G. C., Olive, P. N. and Brand, M. D. (1990) Non-ohmic proton conductance of the mitochondrial inner membrane in hepatocytes. J. Biol. Chem. 265, 12903-12909
    • (1990) J. Biol. Chem. , vol.265 , pp. 12903-12909
    • Nobes, C.D.1    Brown, G.C.2    Olive, P.N.3    Brand, M.D.4
  • 24
    • 0025369214 scopus 로고
    • The proton leak across the mitochondrial inner membrane
    • Brand, M. D. (1990) The proton leak across the mitochondrial inner membrane. Biochim. Biophys. Acta 1018, 128-133
    • (1990) Biochim. Biophys. Acta , vol.1018 , pp. 128-133
    • Brand, M.D.1
  • 26
    • 0032953969 scopus 로고    scopus 로고
    • Contribution of mitochondrial proton leak to respiration rate in working skeletal muscle and liver and to SMR
    • Rolfe, D. F. S., Newman, J. M., Buckingham, J. A., Clark, M. G. and Brand, M. D. (1999) Contribution of mitochondrial proton leak to respiration rate in working skeletal muscle and liver and to SMR. Am. J. Physiol. 276, C692-C699
    • (1999) Am. J. Physiol. , vol.276
    • Rolfe, D.F.S.1    Newman, J.M.2    Buckingham, J.A.3    Clark, M.G.4    Brand, M.D.5
  • 27
    • 0030995005 scopus 로고    scopus 로고
    • The physiological significance of mitochondrial proton leak in animal cells and tissues
    • Rolfe, D. F. S. and Brand, M. D. (1997) The physiological significance of mitochondrial proton leak in animal cells and tissues. Biosci. Rep. 17, 9-16
    • (1997) Biosci. Rep. , vol.17 , pp. 9-16
    • Rolfe, D.F.S.1    Brand, M.D.2
  • 28
    • 24644462789 scopus 로고    scopus 로고
    • Mitochondria and calcium signaling
    • Nicholls, D. G. (2005) Mitochondria and calcium signaling. Cell Calcium 38, 311-317
    • (2005) Cell Calcium , vol.38 , pp. 311-317
    • Nicholls, D.G.1
  • 29
    • 0025238865 scopus 로고
    • A 'top-down' approach to the determination of control coefficients in metabolic control theory
    • Brown, G. C., Hafner, R. P. and Brand, M. D. (1990) A 'top-down' approach to the determination of control coefficients in metabolic control theory. Eur. J. Biochem. 188, 321-325
    • (1990) Eur. J. Biochem. , vol.188 , pp. 321-325
    • Brown, G.C.1    Hafner, R.P.2    Brand, M.D.3
  • 30
    • 0025007883 scopus 로고
    • Control of respiration and oxidative phosphorylation in isolated rat liver cells
    • Brown, G. C., Lakin-Thomas, P. L. and Brand, M. D. (1990) Control of respiration and oxidative phosphorylation in isolated rat liver cells. Eur. J. Biochem. 192, 355-362
    • (1990) Eur. J. Biochem. , vol.192 , pp. 355-362
    • Brown, G.C.1    Lakin-Thomas, P.L.2    Brand, M.D.3
  • 31
    • 0030574107 scopus 로고    scopus 로고
    • Top down metabolic control analysis
    • Brand, M. D. (1996) Top down metabolic control analysis. J. Theor. Biol. 182, 351-360
    • (1996) J. Theor. Biol. , vol.182 , pp. 351-360
    • Brand, M.D.1
  • 32
    • 0031661513 scopus 로고    scopus 로고
    • Top-down elasticity analysis and its application to energy metabolism in isolated mitochondria and intact cells
    • Brand, M. D. (1998) Top-down elasticity analysis and its application to energy metabolism in isolated mitochondria and intact cells. Mol. Cell. Biochem. 184, 13-20
    • (1998) Mol. Cell. Biochem. , vol.184 , pp. 13-20
    • Brand, M.D.1
  • 33
    • 34249804144 scopus 로고    scopus 로고
    • Were inefficient mitochondrial haplogroups selected during migrations of modern humans? A test using modular kinetic analysis of coupling in mitochondria from cybrid cell lines
    • Amo, T. and Brand, M. D. (2007) Were inefficient mitochondrial haplogroups selected during migrations of modern humans? A test using modular kinetic analysis of coupling in mitochondria from cybrid cell lines. Biochem. J. 404, 345-351
    • (2007) Biochem. J. , vol.404 , pp. 345-351
    • Amo, T.1    Brand, M.D.2
  • 34
    • 0030898874 scopus 로고    scopus 로고
    • Regulation analysis of energy metabolism
    • Brand, M. D. (1997) Regulation analysis of energy metabolism. J. Exp. Biol. 200, 193-202
    • (1997) J. Exp. Biol. , vol.200 , pp. 193-202
    • Brand, M.D.1
  • 35
    • 0025854301 scopus 로고
    • Effect of protonmotive force on the relative proton stoichiometries of the mitochondrial proton pumps
    • Hafner, R. P. and Brand, M. D. (1991) Effect of protonmotive force on the relative proton stoichiometries of the mitochondrial proton pumps. Biochem. J. 275, 75-80
    • (1991) Biochem. J. , vol.275 , pp. 75-80
    • Hafner, R.P.1    Brand, M.D.2
  • 36
    • 0028010091 scopus 로고
    • Experimental discrimination between proton leak and redox slip during mitochondrial electron transport
    • Brand, M. D., Chien, L. F. and Diolez, P. (1994) Experimental discrimination between proton leak and redox slip during mitochondrial electron transport. Biochem. J. 297, 27-29 (Pubitemid 24025597)
    • (1994) Biochemical Journal , vol.297 , Issue.1 , pp. 27-29
    • Brand, M.D.1    Chien, L.-F.2    Diolez, P.3
  • 37
    • 0029056231 scopus 로고
    • +/O ratio are independent of electron transport rate in isolated hepatocytes
    • +/O ratio are independent of electron transport rate in isolated hepatocytes. Biochem. J. 310, 379-382
    • (1995) Biochem. J. , vol.310 , pp. 379-382
    • Porter, R.K.1    Brand, M.D.2
  • 38
    • 77049233362 scopus 로고
    • Respiratory enzymes in oxidative phosphorylation. I. Kinetics of oxygen utilization
    • Chance, B. and Williams, G. R. (1955) Respiratory enzymes in oxidative phosphorylation. I. Kinetics of oxygen utilization. J. Biol. Chem. 217, 383-393
    • (1955) J. Biol. Chem. , vol.217 , pp. 383-393
    • Chance, B.1    Williams, G.R.2
  • 39
    • 33846317064 scopus 로고    scopus 로고
    • Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells
    • Wu, M., Neilson, A., Swift, A. L., Moran, R., Tamagnine, J., Parslow, D., Armistead, S., Lemire, K., Orrell, J., Teich, J. et al. (2007) Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. Am. J. Physiol. Cell Physiol. 292, C125-C136
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292
    • Wu, M.1    Neilson, A.2    Swift, A.L.3    Moran, R.4    Tamagnine, J.5    Parslow, D.6    Armistead, S.7    Lemire, K.8    Orrell, J.9    Teich, J.10
  • 41
    • 0017373769 scopus 로고
    • Inter-relationships between proton electrochemical gradient, adenine-nucleotide phosphorylation potential and respiration, during substrate-level and oxidative phosphorylation by mitochondria from brown adipose tissue of cold-adapted guinea-pigs
    • Nicholls, D. G. and Bernson, V. S. (1977) Inter-relationships between proton electrochemical gradient, adenine-nucleotide phosphorylation potential and respiration, during substrate-level and oxidative phosphorylation by mitochondria from brown adipose tissue of cold-adapted guinea-pigs. Eur. J. Biochem. 75, 601-612
    • (1977) Eur. J. Biochem. , vol.75 , pp. 601-612
    • Nicholls, D.G.1    Bernson, V.S.2
  • 42
    • 33745615380 scopus 로고    scopus 로고
    • The physiological regulation of uncoupling proteins
    • Nicholls, D. G. (2006) The physiological regulation of uncoupling proteins. Biochim. Biophys. Acta 1757, 459-466
    • (2006) Biochim. Biophys. Acta , vol.1757 , pp. 459-466
    • Nicholls, D.G.1
  • 43
    • 30044435536 scopus 로고    scopus 로고
    • Stronger control of ATP/ADP by proton leak in pancreatic β-cells than skeletal muscle mitochondria
    • Affourtit, C. and Brand, M. D. (2006) Stronger control of ATP/ADP by proton leak in pancreatic β-cells than skeletal muscle mitochondria. Biochem. J. 393, 151-159
    • (2006) Biochem. J. , vol.393 , pp. 151-159
    • Affourtit, C.1    Brand, M.D.2
  • 44
    • 0027241092 scopus 로고
    • Control of the effective P/O ratio of oxidative phosphorylation in liver mitochondria and hepatocytes
    • Brand, M. D., Harper, M. E. and Taylor, H. C. (1993) Control of the effective P/O ratio of oxidative phosphorylation in liver mitochondria and hepatocytes. Biochem. J. 291, 739-748
    • (1993) Biochem. J. , vol.291 , pp. 739-748
    • Brand, M.D.1    Harper, M.E.2    Taylor, H.C.3
  • 45
    • 0016294206 scopus 로고
    • The influence of respiration and ATP hydrolysis on the proton-electrochemical gradient across the inner membrane of rat-liver mitochondria as determined by ion distribution
    • Nicholls, D. G. (1974) The influence of respiration and ATP hydrolysis on the proton-electrochemical gradient across the inner membrane of rat-liver mitochondria as determined by ion distribution. Eur. J. Biochem. 50, 305-315
    • (1974) Eur. J. Biochem. , vol.50 , pp. 305-315
    • Nicholls, D.G.1
  • 46
    • 0015515511 scopus 로고
    • Mitochondrial from hamster brown-adipose tissue. Regulation of respiration in vitro by variations in volume of the matrix compartment
    • Nicholls, D. G., Grav, H. J. and Lindberg, O. (1972) Mitochondrial from hamster brown-adipose tissue. Regulation of respiration in vitro by variations in volume of the matrix compartment. Eur. J. Biochem. 31, 526-533
    • (1972) Eur. J. Biochem. , vol.31 , pp. 526-533
    • Nicholls, D.G.1    Grav, H.J.2    Lindberg, O.3
  • 47
    • 0024023239 scopus 로고
    • Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio
    • Brown, G. C. and Brand, M. D. (1988) Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio. Biochem. J. 252, 473-479
    • (1988) Biochem. J. , vol.252 , pp. 473-479
    • Brown, G.C.1    Brand, M.D.2
  • 48
    • 0002114258 scopus 로고
    • Measurement of mitochondrial protonmotive force
    • (Brown, G. C. and Cooper, C. E., eds), IRL Press, Oxford
    • Brand, M. D. (1995) Measurement of mitochondrial protonmotive force. In Bioenergetics, a practical approach (Brown, G. C. and Cooper, C. E., eds), pp. 39-62, IRL Press, Oxford
    • (1995) Bioenergetics, a Practical Approach , pp. 39-62
    • Brand, M.D.1
  • 49
    • 0018665167 scopus 로고
    • Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state
    • Kamo, N., Muratsugu, M., Hongoh, R. and Kobatake, Y. (1979) Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state. J. Membr. Biol. 49, 105-121
    • (1979) J. Membr. Biol. , vol.49 , pp. 105-121
    • Kamo, N.1    Muratsugu, M.2    Hongoh, R.3    Kobatake, Y.4
  • 50
    • 0017201717 scopus 로고
    • Safranine as a probe of the mitochondrial membrane potential
    • Akerman, K. E. O. and Wikstrom, M. K. (1976) Safranine as a probe of the mitochondrial membrane potential. FEBS Lett. 68, 191-197
    • (1976) FEBS Lett. , vol.68 , pp. 191-197
    • Akerman, K.E.O.1    Wikstrom, M.K.2
  • 51
    • 0030723518 scopus 로고    scopus 로고
    • The non-ohmic proton leak - 25 Years on
    • Nicholls, D. G. (1997) The non-ohmic proton leak - 25 years on. Biosci. Rep. 17, 251-257
    • (1997) Biosci. Rep. , vol.17 , pp. 251-257
    • Nicholls, D.G.1
  • 54
    • 0014515147 scopus 로고
    • Respiration in vitro of synaptosomes from mammalian cerebral cortex
    • Bradford, H. F. (1969) Respiration in vitro of synaptosomes from mammalian cerebral cortex. J. Neurochem. 16, 675-684
    • (1969) J. Neurochem. , vol.16 , pp. 675-684
    • Bradford, H.F.1
  • 55
    • 0018864653 scopus 로고
    • Energy transduction in intact synaptosomes. Influence of plasma-membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ
    • Scott, I. D. and Nicholls, D. G. (1980) Energy transduction in intact synaptosomes. Influence of plasma-membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ. Biochem. J. 186, 21-33
    • (1980) Biochem. J. , vol.186 , pp. 21-33
    • Scott, I.D.1    Nicholls, D.G.2
  • 56
    • 38149130672 scopus 로고    scopus 로고
    • Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion
    • Affourtit, C. and Brand, M. D. (2008) Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion. Biochem. J. 409, 199-204
    • (2008) Biochem. J. , vol.409 , pp. 199-204
    • Affourtit, C.1    Brand, M.D.2
  • 57
    • 3543030406 scopus 로고    scopus 로고
    • In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate
    • Jekabsons, M. B. and Nicholls, D. G. (2004) In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate. J. Biol. Chem. 279, 32989-33000
    • (2004) J. Biol. Chem. , vol.279 , pp. 32989-33000
    • Jekabsons, M.B.1    Nicholls, D.G.2
  • 58
    • 33747149006 scopus 로고    scopus 로고
    • Bioenergetic analysis of cerebellar granule neurons undergoing apoptosis by potassium/serum deprivation
    • Jekabsons, M. B. and Nicholls, D. G. (2006) Bioenergetic analysis of cerebellar granule neurons undergoing apoptosis by potassium/serum deprivation. Cell Death Differ. 13, 1595-1610
    • (2006) Cell Death Differ. , vol.13 , pp. 1595-1610
    • Jekabsons, M.B.1    Nicholls, D.G.2
  • 59
    • 33644688266 scopus 로고    scopus 로고
    • Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons
    • Vesce, S., Jekabsons, M. B., Johnson-Cadwell, L. I. and Nicholls, D. G. (2005) Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons. J. Biol. Chem. 280, 38720-38728
    • (2005) J. Biol. Chem. , vol.280 , pp. 38720-38728
    • Vesce, S.1    Jekabsons, M.B.2    Johnson-Cadwell, L.I.3    Nicholls, D.G.4
  • 60
    • 33947200596 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in Huntington's disease: The bioenergetics of isolated and in situ mitochondria from transgenic mice
    • Oliveira, J. M., Jekabsons, M. B., Chen, S., Lin, A., Rego, A. C., Goncalves, J., Ellerby, L. M. and Nicholls, D. G. (2007) Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice. J. Neurochem. 101, 241-249
    • (2007) J. Neurochem. , vol.101 , pp. 241-249
    • Oliveira, J.M.1    Jekabsons, M.B.2    Chen, S.3    Lin, A.4    Rego, A.C.5    Goncalves, J.6    Ellerby, L.M.7    Nicholls, D.G.8
  • 61
    • 34249781383 scopus 로고    scopus 로고
    • 'Mild uncoupling' does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress
    • Johnson-Cadwell, L. I., Jekabsons, M. B., Wang, A., Polster, B. M. and Nicholls, D. G. (2007) 'Mild uncoupling' does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress. J. Neurochem. 101, 1619-1631
    • (2007) J. Neurochem. , vol.101 , pp. 1619-1631
    • Johnson-Cadwell, L.I.1    Jekabsons, M.B.2    Wang, A.3    Polster, B.M.4    Nicholls, D.G.5
  • 62
    • 34447122557 scopus 로고    scopus 로고
    • Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone
    • Yadava, N. and Nicholls, D. G. (2007) Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone. J. Neurosci. 27, 7310-7317
    • (2007) J. Neurosci. , vol.27 , pp. 7310-7317
    • Yadava, N.1    Nicholls, D.G.2
  • 63
    • 3342921887 scopus 로고    scopus 로고
    • On-line oxygen uptake rate and culture viability measurement of animal cell culture using microplates with integrated oxygen sensors
    • Deshpande, R. R. and Heinzle, E. (2004) On-line oxygen uptake rate and culture viability measurement of animal cell culture using microplates with integrated oxygen sensors. Biotechnol. Lett. 26, 763-767
    • (2004) Biotechnol. Lett. , vol.26 , pp. 763-767
    • Deshpande, R.R.1    Heinzle, E.2
  • 64
    • 1542648923 scopus 로고    scopus 로고
    • Fluorescence-based cell viability screening assays using water-soluble oxygen probes
    • Hynes, J., Floyd, S., Soini, A. E., O'Connor, R. and Papkovsky, D. B. (2003) Fluorescence-based cell viability screening assays using water-soluble oxygen probes. J. Biomol. Screen. 8, 264-272
    • (2003) J. Biomol. Screen. , vol.8 , pp. 264-272
    • Hynes, J.1    Floyd, S.2    Soini, A.E.3    O'Connor, R.4    Papkovsky, D.B.5
  • 65
    • 33747370385 scopus 로고    scopus 로고
    • The Redox-Bohr group associated with iron-sulfur cluster N2 of complex I
    • Zwicker, K., Galkin, A., Drose, S., Grgic, L., Kerscher, S. and Brandt, U. (2006) The Redox-Bohr group associated with iron-sulfur cluster N2 of complex I. J. Biol. Chem. 281, 23013-23017
    • (2006) J. Biol. Chem. , vol.281 , pp. 23013-23017
    • Zwicker, K.1    Galkin, A.2    Drose, S.3    Grgic, L.4    Kerscher, S.5    Brandt, U.6
  • 66
    • 65649092131 scopus 로고    scopus 로고
    • Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: Spare respiratory capacity and stochastic mitochondrial failure
    • Choi, S. W., Gerencser, A. A. and Nicholls, D. G. (2009) Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: spare respiratory capacity and stochastic mitochondrial failure. J. Neurochem. 109, 1179-1191
    • (2009) J. Neurochem. , vol.109 , pp. 1179-1191
    • Choi, S.W.1    Gerencser, A.A.2    Nicholls, D.G.3
  • 67
    • 0141816763 scopus 로고    scopus 로고
    • Bioenergetics and transmitter release in the isolated nerve terminal
    • Nicholls, D. G. (2003) Bioenergetics and transmitter release in the isolated nerve terminal. Neurochem. Res. 28, 1433-1441
    • (2003) Neurochem. Res. , vol.28 , pp. 1433-1441
    • Nicholls, D.G.1
  • 68
    • 0015973650 scopus 로고
    • Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by α-cyano-4-hydroxycinnamate
    • Halestrap, A. P. and Denton, R. M. (1974) Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by α-cyano-4-hydroxycinnamate. Biochem. J. 138, 313-316
    • (1974) Biochem. J. , vol.138 , pp. 313-316
    • Halestrap, A.P.1    Denton, R.M.2
  • 69
    • 0028884511 scopus 로고
    • Causes of differences in respiration rate of hepatocytes from mammals of different body mass
    • Porter, R. K. and Brand, M. D. (1995) Causes of differences in respiration rate of hepatocytes from mammals of different body mass. Am. J. Physiol. 269, R1213-R1224
    • (1995) Am. J. Physiol. , vol.269
    • Porter, R.K.1    Brand, M.D.2
  • 70
    • 39649122096 scopus 로고    scopus 로고
    • Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T
    • Amo, T., Yadava, N., Oh, R., Nicholls, D. G. and Brand, M. D. (2008) Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T. Gene 411, 69-76
    • (2008) Gene , vol.411 , pp. 69-76
    • Amo, T.1    Yadava, N.2    Oh, R.3    Nicholls, D.G.4    Brand, M.D.5
  • 71
    • 0033179481 scopus 로고    scopus 로고
    • Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes
    • Ainscow, E. K. and Brand, M. D. (1999) Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes. Eur. J. Biochem. 263, 671-685
    • (1999) Eur. J. Biochem. , vol.263 , pp. 671-685
    • Ainscow, E.K.1    Brand, M.D.2
  • 72
    • 0025308492 scopus 로고
    • The mechanism of stimulation of respiration by fatty acids in isolated hepatocytes
    • Nobes, C. D., Hay, Jr, W. W. and Brand, M. D. (1990) The mechanism of stimulation of respiration by fatty acids in isolated hepatocytes. J. Biol. Chem. 265, 12910-12915
    • (1990) J. Biol. Chem. , vol.265 , pp. 12910-12915
    • Nobes, C.D.1    Hay Jr., W.W.2    Brand, M.D.3
  • 73
    • 0029062803 scopus 로고
    • Proportional activation coefficients during stimulation of oxidative phosphorylation by lactate and pyruvate or by vasopressin
    • Korzeniewski, B., Harper, M. E. and Brand, M. D. (1995) Proportional activation coefficients during stimulation of oxidative phosphorylation by lactate and pyruvate or by vasopressin. Biochim. Biophys. Acta 1229, 315-322
    • (1995) Biochim. Biophys. Acta , vol.1229 , pp. 315-322
    • Korzeniewski, B.1    Harper, M.E.2    Brand, M.D.3
  • 74
    • 0024451295 scopus 로고
    • +-ATPase to the rate of respiration of hepatocytes. Effects of thyroid status and fatty acids
    • +-ATPase to the rate of respiration of hepatocytes. Effects of thyroid status and fatty acids. Biochim. Biophys. Acta 976, 241-245
    • (1989) Biochim. Biophys. Acta , vol.976 , pp. 241-245
    • Nobes, C.D.1    Lakin-Thomas, P.L.2    Brand, M.D.3
  • 75
    • 65449174289 scopus 로고    scopus 로고
    • Measuring mitochondrial bioenergetics in INS-1E insulinoma cells
    • Affourtit, C. and Brand, M. D. (2009) Measuring mitochondrial bioenergetics in INS-1E insulinoma cells. Methods Enzymol. 457, 405-424
    • (2009) Methods Enzymol. , vol.457 , pp. 405-424
    • Affourtit, C.1    Brand, M.D.2
  • 77
    • 10244257617 scopus 로고    scopus 로고
    • The integration of mitochondrial calcium transport and storage
    • Nicholls, D. G. and Chalmers, S. (2004) The integration of mitochondrial calcium transport and storage. J. Bioenerg. Biomembr. 36, 277-281
    • (2004) J. Bioenerg. Biomembr. , vol.36 , pp. 277-281
    • Nicholls, D.G.1    Chalmers, S.2
  • 78
    • 33744952060 scopus 로고    scopus 로고
    • Simultaneous monitoring of ionophore- and inhibitor-mediated plasma and mitochondrial membrane potential changes in cultured neurons
    • Nicholls, D. G. (2006) Simultaneous monitoring of ionophore- and inhibitor-mediated plasma and mitochondrial membrane potential changes in cultured neurons. J. Biol. Chem. 281, 14864-14874
    • (2006) J. Biol. Chem. , vol.281 , pp. 14864-14874
    • Nicholls, D.G.1
  • 79
    • 60549109221 scopus 로고    scopus 로고
    • Matrix alkalinization: A novel mitochondrial signal for sustained pancreatic β-cell activation
    • Wiederkehr, A., Park, K. S., Dupont, O., Demaurex, N., Pozzan, T., Cline, G. W. and Wollheim, C. B. (2009) Matrix alkalinization: a novel mitochondrial signal for sustained pancreatic β-cell activation. EMBO J. 28, 417-428
    • (2009) EMBO J. , vol.28 , pp. 417-428
    • Wiederkehr, A.1    Park, K.S.2    Dupont, O.3    Demaurex, N.4    Pozzan, T.5    Cline, G.W.6    Wollheim, C.B.7
  • 80
    • 0034307759 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells
    • Ward, M. W., Rego, A. C., Frenguelli, B. G. and Nicholls, D. G. (2000) Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurosci. 20, 7208-7219
    • (2000) J. Neurosci. , vol.20 , pp. 7208-7219
    • Ward, M.W.1    Rego, A.C.2    Frenguelli, B.G.3    Nicholls, D.G.4
  • 81
    • 34547650971 scopus 로고    scopus 로고
    • Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance
    • Ward, M. W., Huber, H. J., Weisova, P., Dussmann, H., Nicholls, D. G. and Prehn, J. H. (2007) Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance. J. Neurosci. 27, 8238-8249
    • (2007) J. Neurosci. , vol.27 , pp. 8238-8249
    • Ward, M.W.1    Huber, H.J.2    Weisova, P.3    Dussmann, H.4    Nicholls, D.G.5    Prehn, J.H.6
  • 82
    • 67650484137 scopus 로고    scopus 로고
    • Real-time visualization of cytoplasmic calpain activation and calcium deregulation in acute glutamate excitotoxicity
    • Gerencser, A. A., Mark, K. A., Hubbard, A. E., Divakaruni, A. S., Mehrabian, Z., Nicholls, D. G. and Polster, B. M. (2009) Real-time visualization of cytoplasmic calpain activation and calcium deregulation in acute glutamate excitotoxicity. J. Neurochem. 110, 990-1004
    • (2009) J. Neurochem. , vol.110 , pp. 990-1004
    • Gerencser, A.A.1    Mark, K.A.2    Hubbard, A.E.3    Divakaruni, A.S.4    Mehrabian, Z.5    Nicholls, D.G.6    Polster, B.M.7
  • 83
    • 79551521189 scopus 로고    scopus 로고
    • A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells
    • Birket, M. J., Orr, A. L., Gerencser, A. A., Madden, D. T., Vitelli, C., Swistowski, A., Brand, M. D. and Zeng, X. (2011) A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells. J. Cell Sci. 124, 348-358
    • (2011) J. Cell Sci. , vol.124 , pp. 348-358
    • Birket, M.J.1    Orr, A.L.2    Gerencser, A.A.3    Madden, D.T.4    Vitelli, C.5    Swistowski, A.6    Brand, M.D.7    Zeng, X.8
  • 85
    • 40949116689 scopus 로고    scopus 로고
    • Assessing mitochondrial potential, calcium, and redox state in isolated mammalian cells using confocal microscopy
    • Davidson, S. M., Yellon, D. and Duchen, M. R. (2007) Assessing mitochondrial potential, calcium, and redox state in isolated mammalian cells using confocal microscopy. Methods Mol. Biol. 372, 421-430
    • (2007) Methods Mol. Biol. , vol.372 , pp. 421-430
    • Davidson, S.M.1    Yellon, D.2    Duchen, M.R.3
  • 86
    • 79953194894 scopus 로고    scopus 로고
    • Fluorescence measurement of mitochondrial membrane potential changes in cultured cells
    • (Palmeira, C. M. and Moreno, A. J., eds), Humana Press, New York, in the press
    • Nicholls, D. G. (2011) Fluorescence measurement of mitochondrial membrane potential changes in cultured cells. In Mitochondrial Bioenergetics : Methods and Protocols (Palmeira, C. M. and Moreno, A. J., eds), Humana Press, New York, in the press
    • (2011) Mitochondrial Bioenergetics: Methods and Protocols
    • Nicholls, D.G.1
  • 87
    • 70349328545 scopus 로고    scopus 로고
    • Inhibitors of ABC transporters and biophysical methods to study their activity
    • Bartosiewicz, D. and Krasowska, A. (2009) Inhibitors of ABC transporters and biophysical methods to study their activity. Z. Naturforsch. C 64, 454-458
    • (2009) Z. Naturforsch. C , vol.64 , pp. 454-458
    • Bartosiewicz, D.1    Krasowska, A.2
  • 88
    • 0026555280 scopus 로고
    • 2+-dependent changes in the mitochondrial energetics in single dissociated mouse sensory neurons
    • 2+-dependent changes in the mitochondrial energetics in single dissociated mouse sensory neurons. Biochem. J. 283, 41-50
    • (1992) Biochem. J. , vol.283 , pp. 41-50
    • Duchen, M.R.1
  • 89
    • 0028210773 scopus 로고
    • 2+, and volume inside cultured adult rabbit cardiac myocytes during chemical hypoxia: A multiparameter digitized confocal microscopic study
    • Chacon, E., Reece, J. M., Nieminen, A. L., Zahrebelski, G., Herman, B. and Lemasters, J. J. (1994) Distribution of electrical potential, pH, free Ca2+, and volume inside cultured adult rabbit cardiac myocytes during chemical hypoxia: a multiparameter digitized confocal microscopic study. Biophys. J. 66, 942-952 (Pubitemid 24106340)
    • (1994) Biophysical Journal , vol.66 , Issue.4 , pp. 942-952
    • Chacon, E.1    Reece, J.M.2    Nieminen, A.-L.3    Zahrebelski, G.4    Herman, B.5    Lemasters, J.J.6
  • 91
    • 68949150785 scopus 로고    scopus 로고
    • What can mitochondrial heterogeneity tell us about mitochondrial dynamics and autophagy?
    • Wikstrom, J. D., Twig, G. and Shirihai, O. S. (2009) What can mitochondrial heterogeneity tell us about mitochondrial dynamics and autophagy? Int. J. Biochem. Cell Biol. 41, 1914-1927
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 1914-1927
    • Wikstrom, J.D.1    Twig, G.2    Shirihai, O.S.3
  • 92
    • 0026767130 scopus 로고
    • iin type I cells isolated from the rabbit carotid body
    • i in type I cells isolated from the rabbit carotid body. J. Physiol. 450, 33-61
    • (1992) J. Physiol. , vol.450 , pp. 33-61
    • Duchen, M.R.1    Biscoe, T.J.2
  • 93
    • 0028903933 scopus 로고
    • Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
    • Zamzami, N., Marchetti, P., Castedo, M., Zanin, C., Vayssiere, J. L., Petit, P. X. and Kroemer, G. (1995) Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J. Exp. Med. 181, 1661-1672
    • (1995) J. Exp. Med. , vol.181 , pp. 1661-1672
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3    Zanin, C.4    Vayssiere, J.L.5    Petit, P.X.6    Kroemer, G.7
  • 94
    • 0027227273 scopus 로고
    • The quantitative contributions of mitochondrial proton leak and ATP turnover reactions to the changed respiration rates of hepatocytes from rats of different thyroid status
    • Harper, M. E. and Brand, M. D. (1993) The quantitative contributions of mitochondrial proton leak and ATP turnover reactions to the changed respiration rates of hepatocytes from rats of different thyroid status. J. Biol. Chem. 268, 14850-14860
    • (1993) J. Biol. Chem. , vol.268 , pp. 14850-14860
    • Harper, M.E.1    Brand, M.D.2
  • 95
    • 0027933797 scopus 로고
    • The effects of methylprednisolone on oxidative phosphorylation in concanavalin-A-stimulated thymocytes. Top-down elasticity analysis and control analysis
    • Buttgereit, F., Grant, A., Muller, M. and Brand, M. D. (1994) The effects of methylprednisolone on oxidative phosphorylation in concanavalin-A-stimulated thymocytes. Top-down elasticity analysis and control analysis. Eur. J. Biochem. 223, 513-519
    • (1994) Eur. J. Biochem. , vol.223 , pp. 513-519
    • Buttgereit, F.1    Grant, A.2    Muller, M.3    Brand, M.D.4
  • 96
    • 0033041438 scopus 로고    scopus 로고
    • Effects of the mitogen concanavalin A on pathways of thymocyte energy metabolism
    • Krauss, S., Buttgereit, F. and Brand, M. D. (1999) Effects of the mitogen concanavalin A on pathways of thymocyte energy metabolism. Biochim. Biophys. Acta 1412, 129-138
    • (1999) Biochim. Biophys. Acta , vol.1412 , pp. 129-138
    • Krauss, S.1    Buttgereit, F.2    Brand, M.D.3
  • 97
    • 3342941452 scopus 로고    scopus 로고
    • Relationships between superoxide levels and delayed calcium deregulation in cultured cerebellar granule cells exposed continuously to glutamate
    • Vesce, S., Kirk, L. and Nicholls, D. G. (2004) Relationships between superoxide levels and delayed calcium deregulation in cultured cerebellar granule cells exposed continuously to glutamate. J. Neurochem. 90, 683-693
    • (2004) J. Neurochem. , vol.90 , pp. 683-693
    • Vesce, S.1    Kirk, L.2    Nicholls, D.G.3
  • 98
    • 0034781572 scopus 로고    scopus 로고
    • The mechanism of mitochondrial membrane potential retention following release of cytochrome c in apoptotic GT1-7 neural cells
    • Rego, A. C., Vesce, S. and Nicholls, D. G. (2001) The mechanism of mitochondrial membrane potential retention following release of cytochrome c in apoptotic GT1-7 neural cells. Cell Death Differ. 8, 995-1003
    • (2001) Cell Death Differ. , vol.8 , pp. 995-1003
    • Rego, A.C.1    Vesce, S.2    Nicholls, D.G.3
  • 99
    • 0017854835 scopus 로고
    • Intramitochondrial and extramitochondrial concentrations of adenine nucleotides and inorganic phosphate in isolated hepatocytes from fasted rats
    • Akerboom, T. P., Bookelman, H., Zuurendonk, P. F., Van Der Meer, R. and Tager, J. M. (1978) Intramitochondrial and extramitochondrial concentrations of adenine nucleotides and inorganic phosphate in isolated hepatocytes from fasted rats. Eur. J. Biochem. 84, 413-420
    • (1978) Eur. J. Biochem. , vol.84 , pp. 413-420
    • Akerboom, T.P.1    Bookelman, H.2    Zuurendonk, P.F.3    Van Der Meer, R.4    Tager, J.M.5
  • 100
    • 0019882124 scopus 로고
    • Mitochondrial and cytosolic ATP/ADP ratios in rat liver in vivo
    • Schwenke, W. D., Soboll, S., Seitz, H. J. and Sies, H. (1981) Mitochondrial and cytosolic ATP/ADP ratios in rat liver in vivo. Biochem. J. 200, 405-408
    • (1981) Biochem. J. , vol.200 , pp. 405-408
    • Schwenke, W.D.1    Soboll, S.2    Seitz, H.J.3    Sies, H.4
  • 102
    • 0017287004 scopus 로고
    • Role of the adenylate deaminase reaction in regulation of adenine nucleotide metabolism in Ehrlich ascites tumor cells
    • Chapman, A. G., Miller, A. L. and Atkinson, D. E. (1976) Role of the adenylate deaminase reaction in regulation of adenine nucleotide metabolism in Ehrlich ascites tumor cells. Cancer Res. 36, 1144-1150
    • (1976) Cancer Res. , vol.36 , pp. 1144-1150
    • Chapman, A.G.1    Miller, A.L.2    Atkinson, D.E.3
  • 103
    • 0029803056 scopus 로고    scopus 로고
    • A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet
    • Ishiyama, M., Tominaga, H., Shiga, M., Sasamoto, K., Ohkura, Y. and Ueno, K. (1996) A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet. Biol. Pharm. Bull. 19, 1518-1520
    • (1996) Biol. Pharm. Bull. , vol.19 , pp. 1518-1520
    • Ishiyama, M.1    Tominaga, H.2    Shiga, M.3    Sasamoto, K.4    Ohkura, Y.5    Ueno, K.6
  • 104
    • 0014286720 scopus 로고
    • Ultrastructural bases for metabolically linked mechanical activity in mitochondria. II. Electron transport-linked ultrastructural transformations in mitochondria
    • Hackenbrock, C. R. (1968) Ultrastructural bases for metabolically linked mechanical activity in mitochondria. II. Electron transport-linked ultrastructural transformations in mitochondria. J. Cell Biol. 37, 345-369
    • (1968) J. Cell Biol. , vol.37 , pp. 345-369
    • Hackenbrock, C.R.1
  • 105
    • 34347370902 scopus 로고    scopus 로고
    • Oxygen consumption rates in hovering hummingbirds reflect substrate-dependent differences in P/O ratios: Carbohydrate as a 'premium fuel'
    • Welch, Jr, K. C., Altshuler, D. L. and Suarez, R. K. (2007) Oxygen consumption rates in hovering hummingbirds reflect substrate-dependent differences in P/O ratios: carbohydrate as a 'premium fuel'. J. Exp. Biol. 210, 2146-2153
    • (2007) J. Exp. Biol. , vol.210 , pp. 2146-2153
    • Welch Jr., K.C.1    Altshuler, D.L.2    Suarez, R.K.3
  • 106
    • 33847752716 scopus 로고    scopus 로고
    • Mitochondrial function, fibre types and ageing: New insights from human muscle in vivo
    • Conley, K. E., Amara, C. E., Jubrias, S. A. and Marcinek, D. J. (2007) Mitochondrial function, fibre types and ageing: new insights from human muscle in vivo. Exp. Physiol. 92, 333-339
    • (2007) Exp. Physiol. , vol.92 , pp. 333-339
    • Conley, K.E.1    Amara, C.E.2    Jubrias, S.A.3    Marcinek, D.J.4
  • 107
    • 0027234486 scopus 로고
    • Control of oxidative phosphorylation in liver mitochondria and hepatocytes
    • Brand, M. D., Chien, L. F. and Rolfe, D. F. S. (1993) Control of oxidative phosphorylation in liver mitochondria and hepatocytes. Biochem. Soc. Trans. 21, 757-762
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 757-762
    • Brand, M.D.1    Chien, L.F.2    Rolfe, D.F.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.