메뉴 건너뛰기




Volumn 32, Issue 1, 2013, Pages 3-11

Promoter methylation of tumor suppressor genes in esophageal squamous cell carcinoma

Author keywords

CpG island; Esophageal squamous cell carcinoma; Promoter methylation; Tumor marker; Tumor suppressor gene

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; DNA METHYLTRANSFERASE; EPIGALLOCATECHIN GALLATE; N PHTHALOYLTRYPTOPHAN; TUMOR MARKER; ZEBULARINE;

EID: 84872172807     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.011.10381     Document Type: Review
Times cited : (32)

References (117)
  • 2
    • 34250631945 scopus 로고    scopus 로고
    • Esophageal cancer: Cases and causes (part I)
    • Lambert R, Hainaut P. Esophageal cancer: cases and causes (part I). Endoscopy, 2007,39:550-555.
    • (2007) Endoscopy , vol.39 , pp. 550-555
    • Lambert, R.1    Hainaut, P.2
  • 5
    • 33845485257 scopus 로고    scopus 로고
    • Epidemiology and pathogenesis of esophageal cancer
    • Holmes RS, Vaughan TL. Epidemiology and pathogenesis of esophageal cancer. Semin Radiat Oncol, 2007,17:2-9.
    • (2007) Semin Radiat Oncol , vol.17 , pp. 2-9
    • Holmes, R.S.1    Vaughan, T.L.2
  • 6
    • 19444383072 scopus 로고    scopus 로고
    • The molecular mechanisms of oesophageal cancer
    • McCabe ML, Dlamini Z. The molecular mechanisms of oesophageal cancer. Int Immunopharmacol, 2005,5:1113-1130.
    • (2005) Int Immunopharmacol , vol.5 , pp. 1113-1130
    • McCabe, M.L.1    Dlamini, Z.2
  • 7
    • 84856336434 scopus 로고    scopus 로고
    • CpG island methylation status of miRNAs in esophageal squamous cell carcinoma
    • Chen X, Hu H, Guan X, et al. CpG island methylation status of miRNAs in esophageal squamous cell carcinoma. Int J Cancer, 2012,130:1607-1613.
    • (2012) Int J Cancer , vol.130 , pp. 1607-1613
    • Chen, X.1    Hu, H.2    Guan, X.3
  • 8
    • 83555177355 scopus 로고    scopus 로고
    • MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-lik e growth factor 1 receptor
    • Kong KL, Kwong DL, Chan TH, et al. MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-lik e growth factor 1 receptor. Gut, 2011,61:33-42.
    • (2011) Gut , vol.61 , pp. 33-42
    • Kong, K.L.1    Kwong, D.L.2    Chan, T.H.3
  • 9
    • 0031454405 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitors and human cancer
    • Kamb A. Cyclin-dependent kinase inhibitors and human cancer. Curr Top Microbiol Immunol, 1998,227:139-148.
    • (1998) Curr Top Microbiol Immunol , vol.227 , pp. 139-148
    • Kamb, A.1
  • 10
    • 0036732023 scopus 로고    scopus 로고
    • Modes of silencing of p16 in development of esophageal squamous cell carcinoma
    • Tokugawa T, Sugihara H, Tani T, et al. Modes of silencing of p16 in development of esophageal squamous cell carcinoma. Cancer Res, 2002,62: 4938-4944.
    • (2002) Cancer Res , vol.62 , pp. 4938-4944
    • Tokugawa, T.1    Sugihara, H.2    Tani, T.3
  • 11
    • 0032589744 scopus 로고    scopus 로고
    • Mechanisms of inactivation of p14ARF, p15INK4b, and p16INK4a genes in human esopha-geal squamous cell carcinoma
    • Xing EP, Nie Y, Song Y, et al. Mechanisms of inactivation of p14ARF, p15INK4b, and p16INK4a genes in human esopha-geal squamous cell carcinoma. Clin Cancer Res, 1999,5:2704-2713.
    • (1999) Clin Cancer Res , vol.5 , pp. 2704-2713
    • Xing, E.P.1    Nie, Y.2    Song, Y.3
  • 12
    • 0032587192 scopus 로고    scopus 로고
    • Aberrant methylation of p16INK4a and deletion of p15INK4b are frequent events in human esophageal cancer in Linxian, China
    • Xing EP, Nie Y, Wang LD, et al. Aberrant methylation of p16INK4a and deletion of p15INK4b are frequent events in human esophageal cancer in Linxian, China. Carcinogenesis, 1999,20:77-84.
    • (1999) Carcinogenesis , vol.20 , pp. 77-84
    • Xing, E.P.1    Nie, Y.2    Wang, L.D.3
  • 13
    • 0033918563 scopus 로고    scopus 로고
    • Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
    • Dammann R, Li C, Yoon JH, et al. Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat Genet, 2000,25:315-319.
    • (2000) Nat Genet , vol.25 , pp. 315-319
    • Dammann, R.1    Li, C.2    Yoon, J.H.3
  • 14
    • 0037386938 scopus 로고    scopus 로고
    • Promoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma
    • Kuroki T, Trapasso F, Yendamuri S, et al. Promoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma. Clin Cancer Res, 2003,9:1441-1445.
    • (2003) Clin Cancer Res , vol.9 , pp. 1441-1445
    • Kuroki, T.1    Trapasso, F.2    Yendamuri, S.3
  • 15
    • 33645237758 scopus 로고    scopus 로고
    • Aberrant promoter hyper-methylation and silencing of the critical 3p21 tumour suppressor gene, RASSF1A, in Chinese oesophageal squa-mous cell carcinoma
    • Wong ML, Tao Q, Fu L, et al. Aberrant promoter hyper-methylation and silencing of the critical 3p21 tumour suppressor gene, RASSF1A, in Chinese oesophageal squa-mous cell carcinoma. Int J Oncol, 2006,28:767-773.
    • (2006) Int J Oncol , vol.28 , pp. 767-773
    • Wong, M.L.1    Tao, Q.2    Fu, L.3
  • 16
    • 0036799843 scopus 로고    scopus 로고
    • Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer
    • Shibata Y, Haruki N, Kuwabara Y, et al. Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer. Carcinogenesis, 2002,23:1695-1699.
    • (2002) Carcinogenesis , vol.23 , pp. 1695-1699
    • Shibata, Y.1    Haruki, N.2    Kuwabara, Y.3
  • 17
    • 3042515471 scopus 로고    scopus 로고
    • DAP-k inase as a target for drug design in cancer and diseases associated with accelerated cell death
    • Bialik S, Kimchi A. DAP-k inase as a target for drug design in cancer and diseases associated with accelerated cell death. Semin Cancer Biol, 2004,14:283-294.
    • (2004) Semin Cancer Biol , vol.14 , pp. 283-294
    • Bialik, S.1    Kimchi, A.2
  • 18
    • 33645932601 scopus 로고    scopus 로고
    • DAPk protein family and cancer
    • Gozuacik D, Kimchi A. DAPk protein family and cancer. Autophagy, 2006,2:74-79.
    • (2006) Autophagy , vol.2 , pp. 74-79
    • Gozuacik, D.1    Kimchi, A.2
  • 19
    • 33846024654 scopus 로고    scopus 로고
    • Oesophageal squamous cell carcinoma may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa
    • Ishii T, Murakami J, Notohara K, et al. Oesophageal squamous cell carcinoma may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa. Gut, 2007,56:13-19.
    • (2007) Gut , vol.56 , pp. 13-19
    • Ishii, T.1    Murakami, J.2    Notohara, K.3
  • 20
    • 18344389720 scopus 로고    scopus 로고
    • Causal relationship between the loss of RUNX3 expression and gastric cancer
    • Li QL, Ito K, Sakakura C, et al. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell, 2002,109:113-124.
    • (2002) Cell , vol.109 , pp. 113-124
    • Li, Q.L.1    Ito, K.2    Sakakura, C.3
  • 21
    • 36849052340 scopus 로고    scopus 로고
    • Promoter hypermethylation of the RUNX3 gene in esophageal squamous cell carcinoma
    • Long C, Yin B, Lu Q, et al. Promoter hypermethylation of the RUNX3 gene in esophageal squamous cell carcinoma. Cancer Invest, 2007,25:685-690.
    • (2007) Cancer Invest , vol.25 , pp. 685-690
    • Long, C.1    Yin, B.2    Lu, Q.3
  • 22
    • 45549088724 scopus 로고    scopus 로고
    • Differential expression of RUNX genes in human esophageal squamous cell carcinoma: Downregulation of RUNX3 worsens patient prognosis
    • Tonomoto Y, Tachibana M, Dhar DK, et al. Differential expression of RUNX genes in human esophageal squamous cell carcinoma: downregulation of RUNX3 worsens patient prognosis. Oncology, 2007,73:346-356.
    • (2007) Oncology , vol.73 , pp. 346-356
    • Tonomoto, Y.1    Tachibana, M.2    Dhar, D.K.3
  • 23
    • 49649107454 scopus 로고    scopus 로고
    • Epigenetic identification of ubiquitin carboxyl-te rminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors
    • Yu J, Tao Q, Cheung KF, et al. Epigenetic identification of ubiquitin carboxyl-te rminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors. Hepatology, 2008,48: 508-518.
    • (2008) Hepatology , vol.48 , pp. 508-518
    • Yu, J.1    Tao, Q.2    Cheung, K.F.3
  • 24
    • 21144442201 scopus 로고    scopus 로고
    • PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinoma
    • Mandelker DL, Yamashita K, Tokumaru Y, et al. PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinoma. Cancer Res, 2005,65: 4963-4968.
    • (2005) Cancer Res , vol.65 , pp. 4963-4968
    • Mandelker, D.L.1    Yamashita, K.2    Tokumaru, Y.3
  • 25
    • 0033079605 scopus 로고    scopus 로고
    • The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
    • Christofori G, Semb H. The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene. Trends Biochem Sci, 1999,24:73-76.
    • (1999) Trends Biochem Sci , vol.24 , pp. 73-76
    • Christofori, G.1    Semb, H.2
  • 26
    • 0036392129 scopus 로고    scopus 로고
    • Epigenetic versus genetic alterations in the inactivation of E-cadherin
    • Strathdee G. Epigenetic versus genetic alterations in the inactivation of E-cadherin. Semin Cancer Biol, 2002,12:373-379.
    • (2002) Semin Cancer Biol , vol.12 , pp. 373-379
    • Strathdee, G.1
  • 27
    • 0035829016 scopus 로고    scopus 로고
    • E-c adherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells
    • Si HX, Tsao SW, Lam KY, et al. E-c adherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells. Cancer Lett, 2001,173:71-78.
    • (2001) Cancer Lett , vol.173 , pp. 71-78
    • Si, H.X.1    Tsao, S.W.2    Lam, K.Y.3
  • 28
    • 3042766369 scopus 로고    scopus 로고
    • E-cadherin expression in patients with esophageal squamous cell carcinoma: Promoter hypermethylation, Snail overexpression, and clinicopathologic implications
    • Takeno S, Noguchi T, Fumoto S, et al. E-cadherin expression in patients with esophageal squamous cell carcinoma: promoter hypermethylation, Snail overexpression, and clinicopathologic implications. Am J Clin Pathol, 2004, 122:78-84.
    • (2004) Am J Clin Pathol , vol.122 , pp. 78-84
    • Takeno, S.1    Noguchi, T.2    Fumoto, S.3
  • 29
    • 51649127815 scopus 로고    scopus 로고
    • CpG island hypermethylation of E-cadherin (CDH1) and integrin alpha4 is associated with recurrence of early stage esophageal squamous cell carcinoma
    • Lee EJ, Lee BB, Han J, et al. CpG island hypermethylation of E-cadherin (CDH1) and integrin alpha4 is associated with recurrence of early stage esophageal squamous cell carcinoma. Int J Cancer, 2008,123:2073-2079.
    • (2008) Int J Cancer , vol.123 , pp. 2073-2079
    • Lee, E.J.1    Lee, B.B.2    Han, J.3
  • 30
    • 84872187382 scopus 로고    scopus 로고
    • The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/beta-catenin signaling and silenced in common carcinomas
    • [Epub ahead of print]
    • Li L, Ying J, Li H, et al. The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/beta-catenin signaling and silenced in common carcinomas. Oncogene, 2011. [Epub ahead of print]
    • (2011) Oncogene
    • Li, L.1    Ying, J.2    Li, H.3
  • 31
    • 53449083846 scopus 로고    scopus 로고
    • Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors
    • Jin Z, Cheng Y, Olaru A, et al. Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors. Int J Cancer, 2008,123:2331-2336.
    • (2008) Int J Cancer , vol.123 , pp. 2331-2336
    • Jin, Z.1    Cheng, Y.2    Olaru, A.3
  • 32
    • 35448995072 scopus 로고    scopus 로고
    • p16, MGMT, RARbeta2, CLDN3, CRBP and MT1G gene methylation in esophageal squamous cell carcinoma and its precursor lesions
    • Roth MJ, Abnet CC, Hu N, et al. p16, MGMT, RARbeta2, CLDN3, CRBP and MT1G gene methylation in esophageal squamous cell carcinoma and its precursor lesions. Oncol Rep, 2006,15:1591-1597.
    • (2006) Oncol Rep , vol.15 , pp. 1591-1597
    • Roth, M.J.1    Abnet, C.C.2    Hu, N.3
  • 33
    • 78651364770 scopus 로고    scopus 로고
    • Low expression of claudin-4 is associated with poor prognosis in esophageal squamous cell carcinoma
    • Sung CO, Han SY, Kim SH. Low expression of claudin-4 is associated with poor prognosis in esophageal squamous cell carcinoma. Ann Surg Oncol, 2011,18: 273-281.
    • (2011) Ann Surg Oncol , vol.18 , pp. 273-281
    • Sung, C.O.1    Han, S.Y.2    Kim, S.H.3
  • 34
    • 42549142983 scopus 로고    scopus 로고
    • DCC promoter hypermethylation in esophageal squamous cell carcinoma
    • Park HL, Kim MS, Yamashita K, et al. DCC promoter hypermethylation in esophageal squamous cell carcinoma. Int J Cancer, 2008,122:2498-2502.
    • (2008) Int J Cancer , vol.122 , pp. 2498-2502
    • Park, H.L.1    Kim, M.S.2    Yamashita, K.3
  • 35
    • 33748302747 scopus 로고    scopus 로고
    • Genetic or epigenetic silencing of low density lipoprotein receptor-re lated protein 1B expression in oral squamous cell carcinoma
    • Nakagawa T, Pimkhaokham A, Suzuki E, et al. Genetic or epigenetic silencing of low density lipoprotein receptor-re lated protein 1B expression in oral squamous cell carcinoma. Cancer Sci, 2006,97:1070-1074.
    • (2006) Cancer Sci , vol.97 , pp. 1070-1074
    • Nakagawa, T.1    Pimkhaokham, A.2    Suzuki, E.3
  • 36
    • 33244483580 scopus 로고    scopus 로고
    • Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation
    • Ying J, Li H, Seng TJ, et al. Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation. Oncogene, 2006,25: 1070-1080.
    • (2006) Oncogene , vol.25 , pp. 1070-1080
    • Ying, J.1    Li, H.2    Seng, T.J.3
  • 37
    • 77953947951 scopus 로고    scopus 로고
    • Frequent silencing of protocadherin 17, a candidate tumour suppressor for esopha-geal squamous cell carcinoma
    • Haruki S, Imoto I, Kozaki K, et al. Frequent silencing of protocadherin 17, a candidate tumour suppressor for esopha-geal squamous cell carcinoma. Carcinogenesis, 2010,31:1027-1036.
    • (2010) Carcinogenesis , vol.31 , pp. 1027-1036
    • Haruki, S.1    Imoto, I.2    Kozaki, K.3
  • 38
    • 0141885090 scopus 로고    scopus 로고
    • Involvement of TSLC1 in progression of esophageal squamous cell carcinoma
    • Ito T, Shimada Y, Hashimoto Y, et al. Involvement of TSLC1 in progression of esophageal squamous cell carcinoma. Cancer Res, 2003,63:6320-6326.
    • (2003) Cancer Res , vol.63 , pp. 6320-6326
    • Ito, T.1    Shimada, Y.2    Hashimoto, Y.3
  • 39
    • 0038055835 scopus 로고    scopus 로고
    • Variability and regulation of O6-alkylguanine-DNA alkyltransferase
    • Margison GP, Povey AC, Kaina B, et al. Variability and regulation of O6-alkylguanine-DNA alkyltransferase. Carcino-genesis, 2003,24:625-635.
    • (2003) Carcino-genesis , vol.24 , pp. 625-635
    • Margison, G.P.1    Povey, A.C.2    Kaina, B.3
  • 40
    • 31544464704 scopus 로고    scopus 로고
    • Targeted modulation of MGMT: Clinical implications
    • Liu L, Gerson SL. Targeted modulation of MGMT: clinical implications. Clin Cancer Res, 2006,12:328-331.
    • (2006) Clin Cancer Res , vol.12 , pp. 328-331
    • Liu, L.1    Gerson, S.L.2
  • 41
    • 20344382068 scopus 로고    scopus 로고
    • Promoter hypermethylation and inactivation of O(6)-m ethylguanine-DNA methyltransferase in esophageal squamous cell carcinomas and its reactivation in cell lines
    • Fang MZ, Jin Z, Wang Y, et al. Promoter hypermethylation and inactivation of O(6)-m ethylguanine-DNA methyltransferase in esophageal squamous cell carcinomas and its reactivation in cell lines. Int J Oncol, 2005,26:615-622.
    • (2005) Int J Oncol , vol.26 , pp. 615-622
    • Fang, M.Z.1    Jin, Z.2    Wang, Y.3
  • 42
    • 0038687773 scopus 로고    scopus 로고
    • Inactivation of DNA repair gene O6-m ethylguanine-D NA methyltransferase by promoter hyper-methylation and its relation to p53 mutations in esophageal squamous cell carcinoma
    • Zhang L, Lu W, Miao X, et al. Inactivation of DNA repair gene O6-m ethylguanine-D NA methyltransferase by promoter hyper-methylation and its relation to p53 mutations in esophageal squamous cell carcinoma. Carcinogenesis, 2003,24:1039-1044.
    • (2003) Carcinogenesis , vol.24 , pp. 1039-1044
    • Zhang, L.1    Lu, W.2    Miao, X.3
  • 43
    • 38849089235 scopus 로고    scopus 로고
    • Aberrant DNA methylation of P16, MGMT, and hMLH1 genes in combination with MTHFR C677T genetic polymorphism in esophageal squamous cell carcinoma
    • Wang J, Sasco AJ, Fu C, et al. Aberrant DNA methylation of P16, MGMT, and hMLH1 genes in combination with MTHFR C677T genetic polymorphism in esophageal squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev, 2008,17:118-125.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 118-125
    • Wang, J.1    Sasco, A.J.2    Fu, C.3
  • 44
    • 79952196661 scopus 로고    scopus 로고
    • Diet folate, DNA methylation and genetic polymorphisms of MTHFR C677T in association with the prognosis of esophageal squamous cell carcinoma
    • Lu C, Xie H, Wang F, et al. Diet folate, DNA methylation and genetic polymorphisms of MTHFR C677T in association with the prognosis of esophageal squamous cell carcinoma. BMC Cancer, 2011,11:91.
    • (2011) BMC Cancer , vol.11 , pp. 91
    • Lu, C.1    Xie, H.2    Wang, F.3
  • 45
    • 0142123326 scopus 로고    scopus 로고
    • Mismatch repair and response to DNA-damaging antitumour therapies
    • Bignami M, Casorelli I, Karran P. Mismatch repair and response to DNA-damaging antitumour therapies. Eur J Cancer, 2003,39:2142-2149.
    • (2003) Eur J Cancer , vol.39 , pp. 2142-2149
    • Bignami, M.1    Casorelli, I.2    Karran, P.3
  • 46
    • 0028845919 scopus 로고
    • DNA mismatch repair and cancer
    • Chung DC, Rustgi AK. DNA mismatch repair and cancer. Gastroenterology, 1995,109:1685-1699.
    • (1995) Gastroenterology , vol.109 , pp. 1685-1699
    • Chung, D.C.1    Rustgi, A.K.2
  • 47
    • 27544500524 scopus 로고    scopus 로고
    • Promoter methylation of the hMLH1 gene and protein expression of human mutL homolog 1 and human mutS homolog 2 in resected esophageal squamous cell carcinoma
    • Tzao C, Hsu HS, Sun GH, et al. Promoter methylation of the hMLH1 gene and protein expression of human mutL homolog 1 and human mutS homolog 2 in resected esophageal squamous cell carcinoma. J Thorac Cardiovasc Surg, 2005,130:1371.
    • (2005) J Thorac Cardiovasc Surg , vol.130 , pp. 1371
    • Tzao, C.1    Hsu, H.S.2    Sun, G.H.3
  • 48
    • 78149258075 scopus 로고    scopus 로고
    • Microsatellite instability analysis and its correlation with hMLH1 repair gene hypermethylation status in esophageal pathologies including cancers
    • Vasavi M, Kiran V, Ravishankar B, et al. Microsatellite instability analysis and its correlation with hMLH1 repair gene hypermethylation status in esophageal pathologies including cancers. Cancer Biomark, 2010,7:1-10.
    • (2010) Cancer Biomark , vol.7 , pp. 1-10
    • Vasavi, M.1    Kiran, V.2    Ravishankar, B.3
  • 49
    • 33748042301 scopus 로고    scopus 로고
    • Accumulation of promoter methylation suggests epigenetic progression in squamous cell carcinoma of the esophagus
    • Guo M, Ren J, House MG, et al. Accumulation of promoter methylation suggests epigenetic progression in squamous cell carcinoma of the esophagus. Clin Cancer Res, 2006,12:4515-4522.
    • (2006) Clin Cancer Res , vol.12 , pp. 4515-4522
    • Guo, M.1    Ren, J.2    House, M.G.3
  • 50
    • 36048985458 scopus 로고    scopus 로고
    • Detection of methylation of hMSH2 gene promoter region of esophageal cancer
    • [in Chinese]
    • Zhang GY, Ma CX, Liu QL, et al. Detection of methylation of hMSH2 gene promoter region of esophageal cancer. Zhonghua Zhong Liu Za Zhi, 2005, 27:541-543. [in Chinese]
    • (2005) Zhonghua Zhong Liu Za Zhi , vol.27 , pp. 541-543
    • Zhang, G.Y.1    Ma, C.X.2    Liu, Q.L.3
  • 51
    • 0036900616 scopus 로고    scopus 로고
    • FHIT: From gene discovery to cancer treatment and prevention
    • Pekarsky Y, Zanesi N, Palamarchuk A, et al. FHIT: from gene discovery to cancer treatment and prevention. Lancet Oncol, 2002,3:748-754.
    • (2002) Lancet Oncol , vol.3 , pp. 748-754
    • Pekarsky, Y.1    Zanesi, N.2    Palamarchuk, A.3
  • 53
    • 0032145266 scopus 로고    scopus 로고
    • Methylation of the 5' CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas
    • Tanaka H, Shimada Y, Harada H, et al. Methylation of the 5' CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas. Cancer Res, 1998,58:3429-3434.
    • (1998) Cancer Res , vol.58 , pp. 3429-3434
    • Tanaka, H.1    Shimada, Y.2    Harada, H.3
  • 54
    • 0034161988 scopus 로고    scopus 로고
    • Altered expression of Fhit in carcinoma and precarcinomatous lesions of the esophagus
    • Mori M, Mimori K, Shiraishi T, et al. Altered expression of Fhit in carcinoma and precarcinomatous lesions of the esophagus. Cancer Res, 2000,60:1177-1182.
    • (2000) Cancer Res , vol.60 , pp. 1177-1182
    • Mori, M.1    Mimori, K.2    Shiraishi, T.3
  • 55
    • 33646179153 scopus 로고    scopus 로고
    • Aberrant methylation of Fragile Histidine Triad gene is associated with poor prognosis in early stage esophageal squamous cell carcinoma
    • Lee EJ, Lee BB, Kim JW, et al. Aberrant methylation of Fragile Histidine Triad gene is associated with poor prognosis in early stage esophageal squamous cell carcinoma. Eur J Cancer, 2006,42:972-980.
    • (2006) Eur J Cancer , vol.42 , pp. 972-980
    • Lee, E.J.1    Lee, B.B.2    Kim, J.W.3
  • 56
    • 33746357941 scopus 로고    scopus 로고
    • Nicotine induces the fragile histidine triad methylation in human esophageal squamous epithelial cells
    • Soma T, Kaganoi J, Kawabe A, et al. Nicotine induces the fragile histidine triad methylation in human esophageal squamous epithelial cells. Int J Cancer, 2006,119:1023-1027.
    • (2006) Int J Cancer , vol.119 , pp. 1023-1027
    • Soma, T.1    Kaganoi, J.2    Kawabe, A.3
  • 57
    • 33847714231 scopus 로고    scopus 로고
    • Tumor-s uppressive activity of retinoic acid receptor-beta in cancer
    • Xu XC. Tumor-s uppressive activity of retinoic acid receptor-beta in cancer. Cancer Lett, 2007,253:14-24.
    • (2007) Cancer Lett , vol.253 , pp. 14-24
    • Xu, X.C.1
  • 58
    • 0032706665 scopus 로고    scopus 로고
    • Loss of retinoic acid receptor-beta expression is an early event during esophageal carcinogenesis
    • Qiu H, Zhang W, El-Naggar AK, et al. Loss of retinoic acid receptor-beta expression is an early event during esophageal carcinogenesis. Am J Pathol, 1999,155:1519-1523.
    • (1999) Am J Pathol , vol.155 , pp. 1519-1523
    • Qiu, H.1    Zhang, W.2    El-Naggar, A.K.3
  • 59
    • 0034015665 scopus 로고    scopus 로고
    • Lack of correlation between expression of retinoic acid receptor-beta and loss of heterozygosity on chromosome band 3p24 in esophageal cancer
    • Qiu H, Lotan R, Lippman SM, et al. Lack of correlation between expression of retinoic acid receptor-beta and loss of heterozygosity on chromosome band 3p24 in esophageal cancer. Genes Chromosomes Cancer, 2000,28:196-202.
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 196-202
    • Qiu, H.1    Lotan, R.2    Lippman, S.M.3
  • 60
    • 17644394932 scopus 로고    scopus 로고
    • Allelic imbalance of chromosome 1q in esophageal squamous cell carcinomas from China: A novel region of allelic loss and significant association with differentiation
    • Li J, Liu Z, Wang Y, et al. Allelic imbalance of chromosome 1q in esophageal squamous cell carcinomas from China: a novel region of allelic loss and significant association with differentiation. Cancer Lett, 2005,220:221-230.
    • (2005) Cancer Lett , vol.220 , pp. 221-230
    • Li, J.1    Liu, Z.2    Wang, Y.3
  • 61
    • 0242442014 scopus 로고    scopus 로고
    • Hypermethylation-associated inactivation of retinoic acid receptor beta in human esophageal squamous cell carcinoma
    • Wang Y, Fang MZ, Liao J, et al. Hypermethylation-associated inactivation of retinoic acid receptor beta in human esophageal squamous cell carcinoma. Clin Cancer Res, 2003,9:5257-5263.
    • (2003) Clin Cancer Res , vol.9 , pp. 5257-5263
    • Wang, Y.1    Fang, M.Z.2    Liao, J.3
  • 62
    • 0037355974 scopus 로고    scopus 로고
    • Sensitive detection of DNA methylation
    • Cottrell SE, Laird PW. Sensitive detection of DNA methylation. Ann N Y Acad Sci, 2003,983:120-130.
    • (2003) Ann N Y Acad Sci , vol.983 , pp. 120-130
    • Cottrell, S.E.1    Laird, P.W.2
  • 63
    • 3042638418 scopus 로고    scopus 로고
    • Molecular diagnostic applications of DNA methylation technology
    • Cottrell SE. Molecular diagnostic applications of DNA methylation technology. Clin Biochem, 2004,37:595-604.
    • (2004) Clin Biochem , vol.37 , pp. 595-604
    • Cottrell, S.E.1
  • 65
    • 35948943898 scopus 로고    scopus 로고
    • Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer
    • Jin Z, Olaru A, Yang J, et al. Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer. Clin Cancer Res, 2007,13: 6293-6300.
    • (2007) Clin Cancer Res , vol.13 , pp. 6293-6300
    • Jin, Z.1    Olaru, A.2    Yang, J.3
  • 66
    • 61549122390 scopus 로고    scopus 로고
    • Promoter methylation in cytology specimens as an early detection marker for esophageal squamous dysplasia and early esophageal squamous cell carcinoma
    • Adams L, Roth MJ, Abnet CC, et al. Promoter methylation in cytology specimens as an early detection marker for esophageal squamous dysplasia and early esophageal squamous cell carcinoma. Cancer Prev Res (Phila), 2008,1: 357-361.
    • (2008) Cancer Prev Res (Phila) , vol.1 , pp. 357-361
    • Adams, L.1    Roth, M.J.2    Abnet, C.C.3
  • 67
    • 79952376686 scopus 로고    scopus 로고
    • Hypermethylation of multiple tumor-re lated genes associated with DNMT3b up-re gulation served as a biomarker for early diagnosis of esophageal squamous cell carcinoma
    • Li B, Wang B, Niu LJ, et al. Hypermethylation of multiple tumor-re lated genes associated with DNMT3b up-re gulation served as a biomarker for early diagnosis of esophageal squamous cell carcinoma. Epigenetics, 2011,6:307-316.
    • (2011) Epigenetics , vol.6 , pp. 307-316
    • Li, B.1    Wang, B.2    Niu, L.J.3
  • 68
    • 79952951341 scopus 로고    scopus 로고
    • Hypermethylation-m odulated down-re gulation of CDH1 expression contributes to the progression of esophageal cancer
    • Ling ZQ, Li P, Ge MH, et al. Hypermethylation-m odulated down-re gulation of CDH1 expression contributes to the progression of esophageal cancer. Int J Mol Med, 2011,27: 625-635.
    • (2011) Int J Mol Med , vol.27 , pp. 625-635
    • Ling, Z.Q.1    Li, P.2    Ge, M.H.3
  • 69
    • 60549105721 scopus 로고    scopus 로고
    • Qualitative analysis of Adenomatous Polyposis Coli promoter: Hypermethylation, engagement and effects on survival of patients with esophageal cancer in a high risk region of the world, a potential molecular marker
    • Zare M, Jazii FR, Alivand MR, et al. Qualitative analysis of Adenomatous Polyposis Coli promoter: hypermethylation, engagement and effects on survival of patients with esophageal cancer in a high risk region of the world, a potential molecular marker. BMC Cancer, 2009,9:24.
    • (2009) BMC Cancer , vol.9 , pp. 24
    • Zare, M.1    Jazii, F.R.2    Alivand, M.R.3
  • 70
    • 33645734603 scopus 로고    scopus 로고
    • N-m ethyl-D -aspartate receptor type 2B is epigenetically inactivated and exhibits tumor-s uppressive activity in human esophageal cancer
    • Kim MS, Yamashita K, Baek JH, et al. N-m ethyl-D -aspartate receptor type 2B is epigenetically inactivated and exhibits tumor-s uppressive activity in human esophageal cancer. Cancer Res, 2006,66:3409-3418.
    • (2006) Cancer Res , vol.66 , pp. 3409-3418
    • Kim, M.S.1    Yamashita, K.2    Baek, J.H.3
  • 71
    • 59249087794 scopus 로고    scopus 로고
    • Quantitative detection of TIMP-3 promoter hypermethylation and its prognostic significance in esophageal squamous cell carcinoma
    • Ninomiya I, Kawakami K, Fushida S, et al. Quantitative detection of TIMP-3 promoter hypermethylation and its prognostic significance in esophageal squamous cell carcinoma. Oncol Rep, 2008,20:1489-1495.
    • (2008) Oncol Rep , vol.20 , pp. 1489-1495
    • Ninomiya, I.1    Kawakami, K.2    Fushida, S.3
  • 72
    • 78449296221 scopus 로고    scopus 로고
    • Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma
    • Kong KL, Kwong DL, Fu L, et al. Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma. Cancer Res, 2010,70:8832-8841.
    • (2010) Cancer Res , vol.70 , pp. 8832-8841
    • Kong, K.L.1    Kwong, D.L.2    Fu, L.3
  • 73
    • 0031964055 scopus 로고    scopus 로고
    • Inhibition of DNA methylation by 5-a za-2'-deoxycytidine suppresses the growth of human tumor cell lines
    • Bender CM, Pao MM, Jones PA. Inhibition of DNA methylation by 5-a za-2'-deoxycytidine suppresses the growth of human tumor cell lines. Cancer Res, 1998,58:95-101.
    • (1998) Cancer Res , vol.58 , pp. 95-101
    • Bender, C.M.1    Pao, M.M.2    Jones, P.A.3
  • 74
    • 0035988868 scopus 로고    scopus 로고
    • Review of the clinical experience with 5-azacytidine and 5-aza-2'-deoxycytidine in solid tumors
    • Aparicio A, Weber JS. Review of the clinical experience with 5-azacytidine and 5-aza-2'-deoxycytidine in solid tumors. Curr Opin Investig Drugs, 2002,3:627-633.
    • (2002) Curr Opin Investig Drugs , vol.3 , pp. 627-633
    • Aparicio, A.1    Weber, J.S.2
  • 75
    • 34250364447 scopus 로고    scopus 로고
    • Towards clinical application of methylated DNA sequences as cancer biomarkers: A joint NCI's EDRN and NIST workshop on standards, methods, assays, reagents and tools
    • Kagan J, Srivastava S, Barker PE, et al. Towards clinical application of methylated DNA sequences as cancer biomarkers: a joint NCI's EDRN and NIST workshop on standards, methods, assays, reagents and tools. Cancer Res, 2007,67:4545-4549.
    • (2007) Cancer Res , vol.67 , pp. 4545-4549
    • Kagan, J.1    Srivastava, S.2    Barker, P.E.3
  • 76
    • 42649089780 scopus 로고    scopus 로고
    • The methylome: Approaches for global DNA methylation profiling
    • Beck S, Rakyan VK. The methylome: approaches for global DNA methylation profiling. Trends Genet, 2008,24:231-237.
    • (2008) Trends Genet , vol.24 , pp. 231-237
    • Beck, S.1    Rakyan, V.K.2
  • 77
    • 77955728660 scopus 로고    scopus 로고
    • KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas
    • Cheng Y, Geng H, Cheng SH, et al. KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas. Cancer Res, 2010,70:6516-6526.
    • (2010) Cancer Res , vol.70 , pp. 6516-6526
    • Cheng, Y.1    Geng, H.2    Cheng, S.H.3
  • 78
    • 33750261993 scopus 로고    scopus 로고
    • Loss of disabled-2 expression is an early event in esophageal squamous tumorigenesis
    • Anupam K, Tusharkant C, Gupta SD, et al. Loss of disabled-2 expression is an early event in esophageal squamous tumorigenesis. World J Gastroenterol, 2006,12:6041-6045.
    • (2006) World J Gastroenterol , vol.12 , pp. 6041-6045
    • Anupam, K.1    Tusharkant, C.2    Gupta, S.D.3
  • 79
    • 34848924607 scopus 로고    scopus 로고
    • Frequent methylation-associated silencing of a candidate tumor-s uppressor, CRABP1, in esophageal squamous-cell carcinoma
    • Tanaka K, Imoto I, Inoue J, et al. Frequent methylation-associated silencing of a candidate tumor-s uppressor, CRABP1, in esophageal squamous-cell carcinoma. Oncogene, 2007,26:6456-6468.
    • (2007) Oncogene , vol.26 , pp. 6456-6468
    • Tanaka, K.1    Imoto, I.2    Inoue, J.3
  • 80
    • 27144449574 scopus 로고    scopus 로고
    • DNA methylation of genes linked to retinoid signaling in squamous cell carcinoma of the esophagus: DNA methylation of CRBP1 and TIG1 is associated with tumor stage
    • Mizuiri H, Yoshida K, Toge T, et al. DNA methylation of genes linked to retinoid signaling in squamous cell carcinoma of the esophagus: DNA methylation of CRBP1 and TIG1 is associated with tumor stage. Cancer Sci, 2005,96: 571-577.
    • (2005) Cancer Sci , vol.96 , pp. 571-577
    • Mizuiri, H.1    Yoshida, K.2    Toge, T.3
  • 81
    • 79952591142 scopus 로고    scopus 로고
    • Methylation-m ediated gene silencing of suppressor of cytokine signaling-1 (SOCS-1) gene in esophageal squamous cell carcinoma patients of Kashmir valley
    • Hussain S, Singh N, Salam I, et al. Methylation-m ediated gene silencing of suppressor of cytokine signaling-1 (SOCS-1) gene in esophageal squamous cell carcinoma patients of Kashmir valley. J Recept Signal Transduct Res, 2011,31:147-156.
    • (2011) J Recept Signal Transduct Res , vol.31 , pp. 147-156
    • Hussain, S.1    Singh, N.2    Salam, I.3
  • 82
    • 82555192553 scopus 로고    scopus 로고
    • Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma
    • Meng Y, Wang QG, Wang JX, et al. Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma. Dig Dis Sci, 2011,56:3195-3203.
    • (2011) Dig Dis Sci , vol.56 , pp. 3195-3203
    • Meng, Y.1    Wang, Q.G.2    Wang, J.X.3
  • 83
    • 42349108108 scopus 로고    scopus 로고
    • Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer
    • Zhang W, Glockner SC, Guo M, et al. Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. Cancer Res, 2008,68:2764-2772.
    • (2008) Cancer Res , vol.68 , pp. 2764-2772
    • Zhang, W.1    Glockner, S.C.2    Guo, M.3
  • 84
    • 34250310905 scopus 로고    scopus 로고
    • The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyn-geal and esophageal carcinomas
    • Chan SL, Cui Y, van Hasselt A, et al. The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyn-geal and esophageal carcinomas. Lab Invest, 2007,87:644-650.
    • (2007) Lab Invest , vol.87 , pp. 644-650
    • Chan, S.L.1    Cui, Y.2    van Hasselt, A.3
  • 85
    • 77957141708 scopus 로고    scopus 로고
    • WNT5A antagonizes WNT/beta-catenin signaling and is frequently silenced by promoter CpG methylation in esophageal squamous cell carcinoma
    • Li J, Ying J, Fan Y, et al. WNT5A antagonizes WNT/beta-catenin signaling and is frequently silenced by promoter CpG methylation in esophageal squamous cell carcinoma. Cancer Biol Ther, 2010,10:617-624.
    • (2010) Cancer Biol Ther , vol.10 , pp. 617-624
    • Li, J.1    Ying, J.2    Fan, Y.3
  • 86
    • 33846046177 scopus 로고    scopus 로고
    • Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9
    • Lo PH, Leung AC, Kwok CY, et al. Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9. Oncogene, 2007,26:148-157.
    • (2007) Oncogene , vol.26 , pp. 148-157
    • Lo, P.H.1    Leung, A.C.2    Kwok, C.Y.3
  • 87
    • 34648817483 scopus 로고    scopus 로고
    • Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas
    • Jin H, Wang X, Ying J, et al. Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas. Oncogene, 2007,26:7490-7498.
    • (2007) Oncogene , vol.26 , pp. 7490-7498
    • Jin, H.1    Wang, X.2    Ying, J.3
  • 88
    • 33645014254 scopus 로고    scopus 로고
    • Expression of candidate chromosome 3p21.3 tumor suppressor genes and down-re gulation of BLU in some esophageal squamous cell carcinomas
    • Yi Lo PH, Chung Leung AC, Xiong W, et al. Expression of candidate chromosome 3p21.3 tumor suppressor genes and down-re gulation of BLU in some esophageal squamous cell carcinomas. Cancer Lett, 2006,234:184-192.
    • (2006) Cancer Lett , vol.234 , pp. 184-192
    • Yi, L.P.H.1    Chung, L.A.C.2    Xiong, W.3
  • 89
    • 34548108106 scopus 로고    scopus 로고
    • Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer
    • Guo M, House MG, Suzuki H, et al. Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer. Int J Cancer, 2007,121:1219-1226.
    • (2007) Int J Cancer , vol.121 , pp. 1219-1226
    • Guo, M.1    House, M.G.2    Suzuki, H.3
  • 90
    • 67449127092 scopus 로고    scopus 로고
    • CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis
    • Wang Y, Li J, Cui Y, et al. CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis. Cancer Res, 2009,69:5194-5201.
    • (2009) Cancer Res , vol.69 , pp. 5194-5201
    • Wang, Y.1    Li, J.2    Cui, Y.3
  • 91
    • 35348891510 scopus 로고    scopus 로고
    • CMTM5 exhibits tumor suppressor activities and is frequently silenced by methylation in carcinoma cell lines
    • Shao L, Cui Y, Li H, et al. CMTM5 exhibits tumor suppressor activities and is frequently silenced by methylation in carcinoma cell lines. Clin Cancer Res, 2007,13:5756-5762.
    • (2007) Clin Cancer Res , vol.13 , pp. 5756-5762
    • Shao, L.1    Cui, Y.2    Li, H.3
  • 92
    • 33846941189 scopus 로고    scopus 로고
    • The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation
    • Seng TJ, Low JS, Li H, et al. The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation. Oncogene, 2007,26:934-944.
    • (2007) Oncogene , vol.26 , pp. 934-944
    • Seng, T.J.1    Low, J.S.2    Li, H.3
  • 93
    • 0033561527 scopus 로고    scopus 로고
    • Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3
    • Daigo Y, Nishiwaki T, Kawasoe T, et al. Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3. Cancer Res, 1999,59: 1966-1972.
    • (1999) Cancer Res , vol.59 , pp. 1966-1972
    • Daigo, Y.1    Nishiwaki, T.2    Kawasoe, T.3
  • 94
    • 0037714882 scopus 로고    scopus 로고
    • Expression of ECRG4, a novel esophageal cancer-re lated gene, downregulated by CpG island hypermethylation in human esophageal squamous cell carcinoma
    • Yue CM, Deng DJ, Bi MX, et al. Expression of ECRG4, a novel esophageal cancer-re lated gene, downregulated by CpG island hypermethylation in human esophageal squamous cell carcinoma. World J Gastroenterol, 2003,9: 1174-1178.
    • (2003) World J Gastroenterol , vol.9 , pp. 1174-1178
    • Yue, C.M.1    Deng, D.J.2    Bi, M.X.3
  • 95
    • 58749091661 scopus 로고    scopus 로고
    • Identification of aberrant promoter methylation of EDNRB gene in esophageal squamous cell carcinoma
    • Zhao BJ, Sun DG, Zhang M, et al. Identification of aberrant promoter methylation of EDNRB gene in esophageal squamous cell carcinoma. Dis Esophagus, 2009,22:55-61.
    • (2009) Dis Esophagus , vol.22 , pp. 55-61
    • Zhao, B.J.1    Sun, D.G.2    Zhang, M.3
  • 96
    • 57749090287 scopus 로고    scopus 로고
    • EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma
    • Fumoto S, Hiyama K, Tanimoto K, et al. EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma. Cancer Lett, 2009,274:25-32.
    • (2009) Cancer Lett , vol.274 , pp. 25-32
    • Fumoto, S.1    Hiyama, K.2    Tanimoto, K.3
  • 97
    • 57349117010 scopus 로고    scopus 로고
    • Identification of an invasion and tumor-s uppressing gene, Endoglin (ENG), silenced by both epigenetic inactivation and allelic loss in esophageal squamous cell carcinoma
    • Wong VC, Chan PL, Bernabeu C, et al. Identification of an invasion and tumor-s uppressing gene, Endoglin (ENG), silenced by both epigenetic inactivation and allelic loss in esophageal squamous cell carcinoma. Int J Cancer, 2008, 123: 2816-2823.
    • (2008) Int J Cancer , vol.123 , pp. 2816-2823
    • Wong, V.C.1    Chan, P.L.2    Bernabeu, C.3
  • 98
    • 33748870952 scopus 로고    scopus 로고
    • Hypermethylation of the GATA gene family in esophageal cancer
    • Guo M, House MG, Akiyama Y, et al. Hypermethylation of the GATA gene family in esophageal cancer. Int J Cancer, 2006,119:2078-2083.
    • (2006) Int J Cancer , vol.119 , pp. 2078-2083
    • Guo, M.1    House, M.G.2    Akiyama, Y.3
  • 99
    • 79952444349 scopus 로고    scopus 로고
    • Identification of GPX3 epigenetically silenced by CpG methylation in human esophageal squamous cell carcinoma
    • He Y, Wang Y, Li P, et al. Identification of GPX3 epigenetically silenced by CpG methylation in human esophageal squamous cell carcinoma. Dig Dis Sci, 2011,56:681-688.
    • (2011) Dig Dis Sci , vol.56 , pp. 681-688
    • He, Y.1    Wang, Y.2    Li, P.3
  • 100
    • 77951221321 scopus 로고    scopus 로고
    • Functional alterations in the glutathione S-transferase family associated with enhanced occurrence of esophageal carcinoma in China
    • Liu R, Yin L, Pu Y, et al. Functional alterations in the glutathione S-transferase family associated with enhanced occurrence of esophageal carcinoma in China. J Toxicol Environ Health A, 2010,73:471-482.
    • (2010) J Toxicol Environ Health A , vol.73 , pp. 471-482
    • Liu, R.1    Yin, L.2    Pu, Y.3
  • 101
    • 63849230673 scopus 로고    scopus 로고
    • Promoter methylation of HIN-1 in the progression to esophageal squamous cancer
    • Guo M, Ren J, Brock MV, et al. Promoter methylation of HIN-1 in the progression to esophageal squamous cancer. Epigenetics, 2008,3:336-341.
    • (2008) Epigenetics , vol.3 , pp. 336-341
    • Guo, M.1    Ren, J.2    Brock, M.V.3
  • 102
    • 79951735484 scopus 로고    scopus 로고
    • Methylation of the promoter of human leukocyte antigen class I in human esophageal squamous cell carcinoma and its histopathological characteristics
    • Qifeng S, Bo C, Xingtao J, et al. Methylation of the promoter of human leukocyte antigen class I in human esophageal squamous cell carcinoma and its histopathological characteristics. J Thorac Cardiovasc Surg, 2011,141: 808-814.
    • (2011) J Thorac Cardiovasc Surg , vol.141 , pp. 808-814
    • Qifeng, S.1    Bo, C.2    Xingtao, J.3
  • 103
    • 0037457487 scopus 로고    scopus 로고
    • Methylation pattern of HLTF gene in digestive tract cancers
    • Hibi K, Nakayama H, Kanyama Y, et al. Methylation pattern of HLTF gene in digestive tract cancers. Int J Cancer, 2003,104: 433-436.
    • (2003) Int J Cancer , vol.104 , pp. 433-436
    • Hibi, K.1    Nakayama, H.2    Kanyama, Y.3
  • 104
    • 40749087229 scopus 로고    scopus 로고
    • HOP/OB1/NECC1 promoter DNA is frequently hypermethylated and involved in tumorigenic ability in esophageal squamous cell carcinoma
    • Yamashita K, Kim MS, Park HL, et al. HOP/OB1/NECC1 promoter DNA is frequently hypermethylated and involved in tumorigenic ability in esophageal squamous cell carcinoma. Mol Cancer Res, 2008,6:31-41.
    • (2008) Mol Cancer Res , vol.6 , pp. 31-41
    • Yamashita, K.1    Kim, M.S.2    Park, H.L.3
  • 105
    • 79952346845 scopus 로고    scopus 로고
    • Promoter methylation of heat shock protein B2 in human esophageal squamous cell carcinoma
    • Chang X, Yamashita K, Sidransky D, et al. Promoter methylation of heat shock protein B2 in human esophageal squamous cell carcinoma. Int J Oncol, 2011,38:1129-1135.
    • (2011) Int J Oncol , vol.38 , pp. 1129-1135
    • Chang, X.1    Yamashita, K.2    Sidransky, D.3
  • 106
    • 51349083104 scopus 로고    scopus 로고
    • Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas
    • Lee KY, Geng H, Ng KM, et al. Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas. Oncogene, 2008,27:5267-5276.
    • (2008) Oncogene , vol.27 , pp. 5267-5276
    • Lee, K.Y.1    Geng, H.2    Ng, K.M.3
  • 107
    • 29244447735 scopus 로고    scopus 로고
    • Metallothionien 3 expression is frequently down-re gulated in oesophageal squamous cell carcinoma by DNA methylation
    • Smith E, Drew PA, Tian ZQ, et al. Metallothionien 3 expression is frequently down-re gulated in oesophageal squamous cell carcinoma by DNA methylation. Mol Cancer, 2005,4:42.
    • (2005) Mol Cancer , vol.4 , pp. 42
    • Smith, E.1    Drew, P.A.2    Tian, Z.Q.3
  • 108
    • 77949395248 scopus 로고    scopus 로고
    • Neurofilament heavy polypeptide regulates the Akt-beta-catenin pathway in human esophageal squamous cell carcinoma
    • Kim MS, Chang X, LeBron C, et al. Neurofilament heavy polypeptide regulates the Akt-beta-catenin pathway in human esophageal squamous cell carcinoma. PLoS One, 2010,5: e9003.
    • (2010) PLoS One , vol.5
    • Kim, M.S.1    Chang, X.2    Lebron, C.3
  • 109
    • 34648843272 scopus 로고    scopus 로고
    • Hypermethylation of the nel-lik e 1 gene is a common and early event and is associated with poor prognosis in early-s tage esophageal adenocarcinoma
    • Jin Z, Mori Y, Yang J, et al. Hypermethylation of the nel-lik e 1 gene is a common and early event and is associated with poor prognosis in early-s tage esophageal adenocarcinoma. Oncogene, 2007,26:6332-6340.
    • (2007) Oncogene , vol.26 , pp. 6332-6340
    • Jin, Z.1    Mori, Y.2    Yang, J.3
  • 110
    • 36048970800 scopus 로고    scopus 로고
    • p300 expression repression by hypermethylation associated with tumour invasion and metastasis in oesophageal squamous cell carcinoma
    • Zhang C, Li K, Wei L, et al. p300 expression repression by hypermethylation associated with tumour invasion and metastasis in oesophageal squamous cell carcinoma. J Clin Pathol, 2007,60:1249-1253.
    • (2007) J Clin Pathol , vol.60 , pp. 1249-1253
    • Zhang, C.1    Li, K.2    Wei, L.3
  • 111
    • 68349125550 scopus 로고    scopus 로고
    • Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma
    • Zhu C, Qin YR, Xie D, et al. Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma. Oncogene, 2009,28:2821-2828.
    • (2009) Oncogene , vol.28 , pp. 2821-2828
    • Zhu, C.1    Qin, Y.R.2    Xie, D.3
  • 112
    • 36349033101 scopus 로고    scopus 로고
    • Characterization of a novel tumor-suppressor gene PLC delta 1 at 3p22 in esophageal squamous cell carcinoma
    • Fu L, Qin YR, Xie D, et al. Characterization of a novel tumor-suppressor gene PLC delta 1 at 3p22 in esophageal squamous cell carcinoma. Cancer Res, 2007,67:10720-10726.
    • (2007) Cancer Res , vol.67 , pp. 10720-10726
    • Fu, L.1    Qin, Y.R.2    Xie, D.3
  • 113
    • 37449034421 scopus 로고    scopus 로고
    • Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis
    • Jin Z, Mori Y, Hamilton JP, et al. Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis. Cancer, 2008,112:43-49.
    • (2008) Cancer , vol.112 , pp. 43-49
    • Jin, Z.1    Mori, Y.2    Hamilton, J.P.3
  • 114
    • 42049120045 scopus 로고    scopus 로고
    • Monochromosome transfer and microarray analysis identify a critical tumor-s uppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma
    • Ko JM, Chan PL, Yau WL, et al. Monochromosome transfer and microarray analysis identify a critical tumor-s uppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma. Mol Cancer Res, 2008,6:592-603.
    • (2008) Mol Cancer Res , vol.6 , pp. 592-603
    • Ko, J.M.1    Chan, P.L.2    Yau, W.L.3
  • 115
    • 53149100965 scopus 로고    scopus 로고
    • Aberrant promoter methylation of the TPEF gene in esophageal squamous cell carcinoma
    • Zhao BJ, Tan SN, Cui Y, et al. Aberrant promoter methylation of the TPEF gene in esophageal squamous cell carcinoma. Dis Esophagus, 2008,21:582-588.
    • (2008) Dis Esophagus , vol.21 , pp. 582-588
    • Zhao, B.J.1    Tan, S.N.2    Cui, Y.3
  • 116
    • 0142250910 scopus 로고    scopus 로고
    • A tumor-s uppressive role for trypsin in human cancer progression
    • Yamashita K, Mimori K, Inoue H, et al. A tumor-s uppressive role for trypsin in human cancer progression. Cancer Res, 2003,63:6575-6578.
    • (2003) Cancer Res , vol.63 , pp. 6575-6578
    • Yamashita, K.1    Mimori, K.2    Inoue, H.3
  • 117
    • 0038756374 scopus 로고    scopus 로고
    • Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma
    • Kuroki T, Trapasso F, Yendamuri S, et al. Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma. Cancer Res, 2003,63: 3724-3728.
    • (2003) Cancer Res , vol.63 , pp. 3724-3728
    • Kuroki, T.1    Trapasso, F.2    Yendamuri, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.