메뉴 건너뛰기




Volumn 5, Issue 10, 1999, Pages 2704-2713

Mechanisms of inactivation of p14(ARF), p15(INK4b), and p16(INK4a) genes in human esophageal squamous cell carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; MESSENGER RNA; ONCOPROTEIN; PROTEIN P15; PROTEIN P16; RETINOBLASTOMA PROTEIN; CALPONIN HOMOLOG PROTEIN, SCHISTOSOMA JAPONICUM; CDKN2B PROTEIN, HUMAN; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2B; HELMINTH PROTEIN; MUSCLE PROTEIN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

EID: 0032589744     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (183)

References (36)
  • 1
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr, C. J. Cancer cell cycles. Science (Washington DC), 274: 1672-1677, 1996.
    • (1996) Science (Washington DC) , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 4
    • 0029587551 scopus 로고
    • Alternative reading frames of the INk4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • Quelle, D. E., Zindy, F., Ashmun, R. A., and Sherr, C. J. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell, 83: 993-1000, 1995.
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 5
    • 0028168242 scopus 로고
    • p15INK4b is a potential effector of TGF-β-induced cell cycle arrest
    • Hannon, G. J., and Beach, D. p15INK4B is a potential effector of TGF-β-induced cell cycle arrest [see comments]. Nature (Lond.), 371: 257-261, 1994.
    • (1994) Nature (Lond.) , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 6
    • 0030780646 scopus 로고    scopus 로고
    • Disruption of the multiple tumor suppressor gene MTSI/p16(INK4a)/CDKN2 by illegitimate V(D)J recombinase activity in T-cell acute lymphoblastic leukemias
    • Cayuela, J. M., Gardie, B., and Sigaux, F. Disruption of the multiple tumor suppressor gene MTSI/p16(INK4a)/CDKN2 by illegitimate V(D)J recombinase activity in T-cell acute lymphoblastic leukemias. Blood, 90: 3720-3726, 1997.
    • (1997) Blood , vol.90 , pp. 3720-3726
    • Cayuela, J.M.1    Gardie, B.2    Sigaux, F.3
  • 7
    • 0031771497 scopus 로고    scopus 로고
    • The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53
    • Robertson, K. D., and Jones, P. A. The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53. Mol. Cell. Biol., 18: 6457-6473, 1998.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 6457-6473
    • Robertson, K.D.1    Jones, P.A.2
  • 8
    • 0031710479 scopus 로고    scopus 로고
    • The INK4a/ARF tumor suppressor: One gene-two products-two pathways
    • Chin, L., Pomerantz, J., and DePinho, R. A. The INK4a/ARF tumor suppressor: one gene-two products-two pathways. Trends Biochem. Sci., 23: 291-296, 1998.
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 291-296
    • Chin, L.1    Pomerantz, J.2    DePinho, R.A.3
  • 9
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano, M., Hannon, G. J., and Beach, D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 [see comments]. Nature (Lond.), 366: 704-777, 1993.
    • (1993) Nature (Lond.) , vol.366 , pp. 704-777
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 11
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano, M., Lin, A. W., McCurrach, M. E., Beach, D., and Lowe, S. W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell, 88: 593-602, 1997.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 12
    • 0032504784 scopus 로고    scopus 로고
    • p19ARF links the tumour suppressor p53 to Ras
    • Palmero, I., Pantoja, C., and Serrano, M. p19ARF links the tumour suppressor p53 to Ras. Nature (Lond.), 595: 125-126, 1998.
    • (1998) Nature (Lond.) , vol.595 , pp. 125-126
    • Palmero, I.1    Pantoja, C.2    Serrano, M.3
  • 14
    • 0029134016 scopus 로고
    • Role of the cyclin-dependent kinase inhibitors in the development of cancer
    • Hirama, T., and Koeffler, H. P. Role of the cyclin-dependent kinase inhibitors in the development of cancer. Blood, 86: 841-854, 1995.
    • (1995) Blood , vol.86 , pp. 841-854
    • Hirama, T.1    Koeffler, H.P.2
  • 17
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTSI gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman, J. G., Merlo, A., Mao, L., Lapidus, R. G., Issa, J. P., Davidson, N. E., Sidransky, D., and Baylin, S. B. Inactivation of the CDKN2/p16/MTSI gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res., 55: 4525-4530, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.P.5    Davidson, N.E.6    Sidransky, D.7    Baylin, S.B.8
  • 18
    • 0031025368 scopus 로고    scopus 로고
    • Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies
    • Herman, J. G., Civin, C. I., Issa, J. P., Collector, M. I., Sharkis, S. J., and Baylin, S. B. Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies. Cancer Res., 57: 837-841, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 837-841
    • Herman, J.G.1    Civin, C.I.2    Issa, J.P.3    Collector, M.I.4    Sharkis, S.J.5    Baylin, S.B.6
  • 19
    • 0030025518 scopus 로고    scopus 로고
    • Compilation of somatic mutations of the CDKN2 gene in human cancers: Non-random distribution of base substitutions
    • Pollock, P. M., Pearson, J. V., and Hayward, N. K. Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitutions. Genes Chromosomes Cancer, 15: 77-88, 1996.
    • (1996) Genes Chromosomes Cancer , vol.15 , pp. 77-88
    • Pollock, P.M.1    Pearson, J.V.2    Hayward, N.K.3
  • 21
    • 0031987331 scopus 로고    scopus 로고
    • Genomic alterations of the p19ARF encoding exons in T-cell acute lymphoblastic leukemia
    • Gardie, B., Cayuela, J. M., Martini, S., and Sigaux, F. Genomic alterations of the p19ARF encoding exons in T-cell acute lymphoblastic leukemia. Blood, 91: 1016-1020, 1998.
    • (1998) Blood , vol.91 , pp. 1016-1020
    • Gardie, B.1    Cayuela, J.M.2    Martini, S.3    Sigaux, F.4
  • 23
    • 0030728468 scopus 로고    scopus 로고
    • Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
    • Kamijo, T., Zindy, F., Roussel, M. F., Quelle, D. E., Downing, J. R., Ashmun, R. A., Grosveld, G., and Sherr, C. J. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell, 91: 649-659, 1997.
    • (1997) Cell , vol.91 , pp. 649-659
    • Kamijo, T.1    Zindy, F.2    Roussel, M.F.3    Quelle, D.E.4    Downing, J.R.5    Ashmun, R.A.6    Grosveld, G.7    Sherr, C.J.8
  • 24
    • 0031454405 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitors and human cancer
    • Kamb, A. Cyclin-dependent kinase inhibitors and human cancer. Curr. Top. Microbiol. Immunol., 227: 139-148, 1998.
    • (1998) Curr. Top. Microbiol. Immunol. , vol.227 , pp. 139-148
    • Kamb, A.1
  • 25
    • 0031030325 scopus 로고    scopus 로고
    • Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF
    • Quelle, D. E., Cheng, M., Ashmun, R. A., and Sherr, C. J. Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF. Proc. Natl. Acad. Sci. USA, 94: 669-673, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 669-673
    • Quelle, D.E.1    Cheng, M.2    Ashmun, R.A.3    Sherr, C.J.4
  • 26
    • 0029664483 scopus 로고    scopus 로고
    • p16INK4a: A gene with a dual capacity to encode unrelated proteins that inhibit cell cycle progression
    • Larsen, C. J. p16INK4a: a gene with a dual capacity to encode unrelated proteins that inhibit cell cycle progression. Oncogene, 12: 2041-2044, 1996.
    • (1996) Oncogene , vol.12 , pp. 2041-2044
    • Larsen, C.J.1
  • 27
    • 0029993450 scopus 로고    scopus 로고
    • Role of the INK4a locus in tumor suppression and cell mortality
    • Serrano, M., Lee, H., Chin, L., Cordon-Cardo, C., Beach, D., and DePinho, R. A. Role of the INK4a locus in tumor suppression and cell mortality. Cell, 85: 27-37, 1996.
    • (1996) Cell , vol.85 , pp. 27-37
    • Serrano, M.1    Lee, H.2    Chin, L.3    Cordon-Cardo, C.4    Beach, D.5    DePinho, R.A.6
  • 29
    • 0031029580 scopus 로고    scopus 로고
    • Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines
    • Sangfelt, O., Erickson, S., Einhorn, S., and Grander, D. Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines. Oncogene, 14: 415-423, 1997.
    • (1997) Oncogene , vol.14 , pp. 415-423
    • Sangfelt, O.1    Erickson, S.2    Einhorn, S.3    Grander, D.4
  • 30
    • 0030714115 scopus 로고    scopus 로고
    • Methylation of the multi tumor suppressor gene-2 (MTS2, CDKN1, p15INK4B) in childhood acute lymphoblastic leukemia
    • Iravani, M., Dhat, R., and Price, C. M. Methylation of the multi tumor suppressor gene-2 (MTS2, CDKN1, p15INK4B) in childhood acute lymphoblastic leukemia. Oncogene, 15: 2609-2614, 1997.
    • (1997) Oncogene , vol.15 , pp. 2609-2614
    • Iravani, M.1    Dhat, R.2    Price, C.M.3
  • 32
    • 9444268107 scopus 로고    scopus 로고
    • Inactivation of the CDKN2 gene by homozygous deletion and de novo methylation is associated with advanced stage esophageal squamous cell carcinoma
    • Maesawa, C., Tamura, G., Nishizuka, S., Ogasawara, S., Ishida, K., Terashima, M., Sakata, K., Sato, N., Saito, K., and Satodate, R. Inactivation of the CDKN2 gene by homozygous deletion and de novo methylation is associated with advanced stage esophageal squamous cell carcinoma. Cancer Res., 56: 3875-3878, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 3875-3878
    • Maesawa, C.1    Tamura, G.2    Nishizuka, S.3    Ogasawara, S.4    Ishida, K.5    Terashima, M.6    Sakata, K.7    Sato, N.8    Saito, K.9    Satodate, R.10
  • 33
    • 0030897676 scopus 로고    scopus 로고
    • p16 tumor suppressor gene mutations in chinese esophageal carcinomas in Hong Kong
    • Chan, W. C., Tang, C. M., Lau, K. W., and Lung, M. L. p16 tumor suppressor gene mutations in Chinese esophageal carcinomas in Hong Kong. Cancer Lett., 115: 201-206, 1997.
    • (1997) Cancer Lett. , vol.115 , pp. 201-206
    • Chan, W.C.1    Tang, C.M.2    Lau, K.W.3    Lung, M.L.4
  • 35
    • 0030459140 scopus 로고    scopus 로고
    • The role of DNA methylation in cancer genetic and epigenetics
    • Laird, P. W., and Jaenisch, R. The role of DNA methylation in cancer genetic and epigenetics. Annu. Rev. Genet., 30: 441-464, 1996.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 441-464
    • Laird, P.W.1    Jaenisch, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.