-
1
-
-
0032948005
-
Synergy of demethylation and histone deacetylase inhibition in the re-expression of gene silenced in cancer
-
Cameron EE, Bachman KE, Myohanen S, et al. Synergy of demethylation and histone deacetylase inhibition in the re-expression of gene silenced in cancer. Nat Genet 1999;21:103-7.
-
(1999)
Nat Genet
, vol.21
, pp. 103-107
-
-
Cameron, E.E.1
Bachman, K.E.2
Myohanen, S.3
-
2
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003;349:2042-54.
-
(2003)
N Engl J Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
3
-
-
0035048449
-
Histone deacetylase induce angiogenesis by negative regulation of tumor suppressor genes
-
Kim MS, Kwon HJ, Lee YM, et al. Histone deacetylase induce angiogenesis by negative regulation of tumor suppressor genes. Nat Med 2001;7:437-43.
-
(2001)
Nat Med
, vol.7
, pp. 437-443
-
-
Kim, M.S.1
Kwon, H.J.2
Lee, Y.M.3
-
4
-
-
0242442588
-
Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer
-
Belinsky SA, Klinge DM, Stidley CA, et al. Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer. Cancer Res 2003;63:7089-93.
-
(2003)
Cancer Res
, vol.63
, pp. 7089-7093
-
-
Belinsky, S.A.1
Klinge, D.M.2
Stidley, C.A.3
-
5
-
-
0012508834
-
Pharmacological unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma
-
Yamashita K, Upadhyay S, Osada M, et al. Pharmacological unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. Cancer Cell 2002;2:485-95.
-
(2002)
Cancer Cell
, vol.2
, pp. 485-495
-
-
Yamashita, K.1
Upadhyay, S.2
Osada, M.3
-
6
-
-
4344628907
-
Inverse Correlation between Cyclin A1 Hypermethylation and p53 Mutation in Head and Neck Cancer Identified by Reversal of Epigenetic Silencing
-
Tokumaru Y, Yamashita K, Osada M, et al. Inverse Correlation between Cyclin A1 Hypermethylation and p53 Mutation in Head and Neck Cancer Identified by Reversal of Epigenetic Silencing. Cancer Res 2004;64:5982-7.
-
(2004)
Cancer Res
, vol.64
, pp. 5982-5987
-
-
Tokumaru, Y.1
Yamashita, K.2
Osada, M.3
-
7
-
-
21144442201
-
PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinoma
-
Mandelker D, Yamashita K, Tokumaru Y, et al. PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinoma. Cancer Res 2005;65:4963-8.
-
(2005)
Cancer Res
, vol.65
, pp. 4963-4968
-
-
Mandelker, D.1
Yamashita, K.2
Tokumaru, Y.3
-
8
-
-
33645734603
-
NMDA receptor type 2B is epigenetically inactivated and exhibits tumor suppressor activity in human esophageal cancer
-
Kim MS, Yamashita K, Baek JH, et al. NMDA receptor type 2B is epigenetically inactivated and exhibits tumor suppressor activity in human esophageal cancer. Cancer Res 2006;66:3409-18.
-
(2006)
Cancer Res
, vol.66
, pp. 3409-3418
-
-
Kim, M.S.1
Yamashita, K.2
Baek, J.H.3
-
9
-
-
0038709289
-
Clinical significance of secreted protein acidic and rich in cystein in esophageal carcinoma and its relation to carcinoma progression
-
Yamashita K, Upadhay S, Mimori K, et al. Clinical significance of secreted protein acidic and rich in cystein in esophageal carcinoma and its relation to carcinoma progression. Cancer 2003;97:2412-9.
-
(2003)
Cancer
, vol.97
, pp. 2412-2419
-
-
Yamashita, K.1
Upadhay, S.2
Mimori, K.3
-
10
-
-
2342580668
-
Differential expression of MMP and uPA systems and prognostic relevance of their expression in esophageal squamous cell carcinoma
-
Yamashita K, Tanaka Y, Mimori K, et al. Differential expression of MMP and uPA systems and prognostic relevance of their expression in esophageal squamous cell carcinoma. Int J Cancer 2004;110:201-7.
-
(2004)
Int J Cancer
, vol.110
, pp. 201-207
-
-
Yamashita, K.1
Tanaka, Y.2
Mimori, K.3
-
11
-
-
0142250910
-
A tumor suppressor role for trypsin in human cancer progression
-
Yamashita K, Mimori K, Inoue H, et al. A tumor suppressor role for trypsin in human cancer progression. Cancer Res 2003;63:6575-8.
-
(2003)
Cancer Res
, vol.63
, pp. 6575-6578
-
-
Yamashita, K.1
Mimori, K.2
Inoue, H.3
-
12
-
-
0038795261
-
MAL gene expression in esophageal cancer suppresses motility, invasion, and tumorigenicity and enhances apoptosis through the Fas pathway
-
Mimori K, Shiraishi T, Mashino K, et al. MAL gene expression in esophageal cancer suppresses motility, invasion, and tumorigenicity and enhances apoptosis through the Fas pathway. Oncogene 2003;22:3463-71.
-
(2003)
Oncogene
, vol.22
, pp. 3463-3471
-
-
Mimori, K.1
Shiraishi, T.2
Mashino, K.3
-
13
-
-
33645736546
-
PGP9.5 methylation in diffuse type gastric cancer
-
Yamashita K, Park LM, Kim MS, et al. PGP9.5 methylation in diffuse type gastric cancer. Cancer Res 2006;66:3921-7.
-
(2006)
Cancer Res
, vol.66
, pp. 3921-3927
-
-
Yamashita, K.1
Park, L.M.2
Kim, M.S.3
-
14
-
-
4043181214
-
Cancer genes and pathways they control
-
Vogelstein B, Kinzler KW. Cancer genes and pathways they control. Nat Med 2004;10:789-99.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
15
-
-
3843055813
-
Loss of HOP tumor suppressor expression in head and neck squamous cell carcinoma
-
Lemaire F, Millon R, Muller D, et al. Loss of HOP tumor suppressor expression in head and neck squamous cell carcinoma. Br J Cancer 2004;91:258-61.
-
(2004)
Br J Cancer
, vol.91
, pp. 258-261
-
-
Lemaire, F.1
Millon, R.2
Muller, D.3
-
16
-
-
0033918563
-
Epigenetic inactivation of a RAS association domain family protein from lung tumor suppressor locus 3p21.3
-
Dammann R, Li C, Yoon JH, et al. Epigenetic inactivation of a RAS association domain family protein from lung tumor suppressor locus 3p21.3. Nat Genet 2000;25:315-9.
-
(2000)
Nat Genet
, vol.25
, pp. 315-319
-
-
Dammann, R.1
Li, C.2
Yoon, J.H.3
-
17
-
-
0035042611
-
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth expression activity
-
Yoshikawa H, Matsubara K, Qian GS, et al. SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth expression activity. Nat Genet 2001;28:29-35.
-
(2001)
Nat Genet
, vol.28
, pp. 29-35
-
-
Yoshikawa, H.1
Matsubara, K.2
Qian, G.S.3
-
18
-
-
0035072880
-
TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer
-
Kuramochi M, Fukuhara H, Nokubuni T, et al. TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer. Nat Genet 2001;27:427-30.
-
(2001)
Nat Genet
, vol.27
, pp. 427-430
-
-
Kuramochi, M.1
Fukuhara, H.2
Nokubuni, T.3
-
19
-
-
18344389720
-
Causal relationship between the loss of RUNX3 expression and gastric cancer
-
Li Q-L, Ito K, Sakakura C, et al. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell 2002;109:113-24.
-
(2002)
Cell
, vol.109
, pp. 113-124
-
-
Li, Q.-L.1
Ito, K.2
Sakakura, C.3
-
20
-
-
0037289066
-
NECC1, a candidate choriocarcinoma suppressor gene that encodes a homeobox consensus motif
-
Asanoma K, Matsuda T, kondo H, et al. NECC1, a candidate choriocarcinoma suppressor gene that encodes a homeobox consensus motif. Genomics 2003;81:15-25.
-
(2003)
Genomics
, vol.81
, pp. 15-25
-
-
Asanoma, K.1
Matsuda, T.2
kondo, H.3
-
21
-
-
18644364557
-
Modulation of cardiac growth and development by HOP, an unusual homeodomain protein
-
Shin CH, Liu ZP, Passier R, et al. Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell 2002;110:725-35.
-
(2002)
Cell
, vol.110
, pp. 725-735
-
-
Shin, C.H.1
Liu, Z.P.2
Passier, R.3
-
22
-
-
18644374460
-
Hop is an unusual homeobox gene that modulates cardiac development
-
Chen F, Kook H, Milewski R, et al. Hop is an unusual homeobox gene that modulates cardiac development. Cell 2002;110:713-23.
-
(2002)
Cell
, vol.110
, pp. 713-723
-
-
Chen, F.1
Kook, H.2
Milewski, R.3
-
23
-
-
0034665274
-
SRF-dependent gene expression is required for PI3-kinase-regulated cell proliferation
-
Poser S, Impey S, Trinh K, et al. SRF-dependent gene expression is required for PI3-kinase-regulated cell proliferation. EMBO J 2000;19:4955-66.
-
(2000)
EMBO J
, vol.19
, pp. 4955-4966
-
-
Poser, S.1
Impey, S.2
Trinh, K.3
-
24
-
-
85047694248
-
Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop
-
Kook H, Lepore JJ, Gitler AD, et al. Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop. J Clin Invest 2003;112:863-71.
-
(2003)
J Clin Invest
, vol.112
, pp. 863-871
-
-
Kook, H.1
Lepore, J.J.2
Gitler, A.D.3
-
25
-
-
33746617492
-
Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulumonary gene expression
-
Yin Z, Gonzales L, Kolla V, et al. Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulumonary gene expression. Am J Physiol Lung Cell Mol Physiol 2006;291:L191-9.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Yin, Z.1
Gonzales, L.2
Kolla, V.3
-
26
-
-
0242552587
-
GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer
-
Akiyama Y, Watkins N, Suzuki H, et al. GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer. Mol Cell Biol 2003;23:8429-39.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8429-8439
-
-
Akiyama, Y.1
Watkins, N.2
Suzuki, H.3
-
27
-
-
12544260190
-
Global analysis of altered gene expressions during the process of esophageal squamous cell carcinogenesis in the rat: A study combined with a laser microdissection and a cDNA microarray
-
Nishida K, Mine S, Utunomiya T, et al. Global analysis of altered gene expressions during the process of esophageal squamous cell carcinogenesis in the rat: a study combined with a laser microdissection and a cDNA microarray. Cancer Res 2005;65:401-9.
-
(2005)
Cancer Res
, vol.65
, pp. 401-409
-
-
Nishida, K.1
Mine, S.2
Utunomiya, T.3
-
28
-
-
33749024160
-
Detection of aberrant methylation of four genes in plasma DNA for detetion of breast cancer
-
Hoque MO, Feng Q, Toure P, et al. Detection of aberrant methylation of four genes in plasma DNA for detetion of breast cancer. J Clin Oncol 2006;24:4262-9.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4262-4269
-
-
Hoque, M.O.1
Feng, Q.2
Toure, P.3
-
29
-
-
33746716987
-
Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection
-
Hoque MO, Begum S, Topalogu O, et al. Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection. J Natl Cancer Inst 2006;98:996-1004.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 996-1004
-
-
Hoque, M.O.1
Begum, S.2
Topalogu, O.3
-
30
-
-
27244450828
-
Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects
-
Hoque MO, Topalogu O, Begum S, et al. Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects. J Clin Oncol 2005;23:6569-75.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6569-6575
-
-
Hoque, M.O.1
Topalogu, O.2
Begum, S.3
-
31
-
-
1642272931
-
Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis
-
Xing M, Cohen Y, Mambo E, et al. Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis. Cancer Res 2004;64:1664-8.
-
(2004)
Cancer Res
, vol.64
, pp. 1664-1668
-
-
Xing, M.1
Cohen, Y.2
Mambo, E.3
-
32
-
-
33747463915
-
RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI-associated endometrial carcinoma
-
Kang S, Lee JM, Jeon ES, et al. RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI-associated endometrial carcinoma. Int J Cancer 2006;119:1316-21.
-
(2006)
Int J Cancer
, vol.119
, pp. 1316-1321
-
-
Kang, S.1
Lee, J.M.2
Jeon, E.S.3
-
33
-
-
0034625043
-
AIS is an oncogene amplified in squamous cell carcinoma
-
Hibi K, Trink B, Patturajan M, et al. AIS is an oncogene amplified in squamous cell carcinoma. Proc Natl Acad Sci U S A 2000;97:5462-7.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 5462-5467
-
-
Hibi, K.1
Trink, B.2
Patturajan, M.3
-
34
-
-
0037134020
-
-
Brummelkamp T, Bernards R, Agami R: a system for stable expression of short interfering RNAs in mammalian cells. Science 2002;296:550-3.
-
Brummelkamp T, Bernards R, Agami R: a system for stable expression of short interfering RNAs in mammalian cells. Science 2002;296:550-3.
-
-
-
|