Epigenetic disruption of interferon-γ response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas

Oncogene

Volumn 27, Issue 39, 2008, Pages 5267-5276

  Lee, K Y ^a   Geng, H ^a   Ng, K M ^a   Yu, J ^b   Van Hasselt, A ^b   Cao, Y ^c   Zeng, Y X ^d   Wong, A H Y ^a   Wang, X ^a   Ying, J ^a   Srivastava, G ^e   Lung, M L ^f   Wang, L D ^g   Kwok, T T ^b   Levi, B Z ^h   Chan, A T C ^a   Sung, J J Y ^b   Tao, Q ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c Central South University   (China)

^d SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^e UNIVERSITY OF HONG KONG   (Hong Kong)

^f HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^g ZHENGZHOU UNIVERSITY   (China)

^h TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Carcinoma; CpG island; IRF8; Methylation; Tumor suppressor gene

Indexed keywords

GAMMA INTERFERON; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN;

ARTICLE; BREAST CARCINOMA; CELL DIFFERENTIATION; CELL GROWTH; CELL STRAIN HCT116; CLONOGENESIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; DNA METHYLATION; ESOPHAGUS CARCINOMA; FETUS; GENE DELETION; GENE SILENCING; GENETIC EPIGENESIS; HOST RESISTANCE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREGULATION; LUNG CARCINOMA; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE; UTERINE CERVIX CARCINOMA;

CELL LINE, TUMOR; DNA METHYLATION; DOWN-REGULATION; EPIGENESIS, GENETIC; ESOPHAGEAL NEOPLASMS; GENE SILENCING; HUMANS; INTERFERON REGULATORY FACTORS; INTERFERON TYPE II; NASOPHARYNGEAL NEOPLASMS; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 51349083104     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.147     Document Type: Article

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