Bim, a proapoptotic protein, up-regulated via transcription factor E2F1-dependent mechanism, functions as a prosurvival molecule in cancer

Journal of Biological Chemistry

Volumn 288, Issue 1, 2013, Pages 368-381

  Gogada, Raghu ^a   Yadav, Neelu ^a   Liu, Junwei ^b   Tang, Shaohua ^b   Zhang, Dianmu ^a   Schneider, Andrea ^a   Seshadri, Athul ^a   Sun, Leimin ^a   Aldaz, C Marcelo ^b   Tang, Dean G ^b   Chandra, Dhyan ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER CELLS; CANCER CELLS; CELL CYTOPLASM; CELL ROUNDING; CYTOCHROME C; EPITHELIAL CANCER CELLS; IN-SILICO; LUCIFERASE ACTIVITIES; LUCIFERASE ASSAYS; MICRO-INJECTION; PRO-APOPTOTIC FUNCTION; QUANTITATIVE REAL TIME PCR; TUMOR CELLS; UP-REGULATION;

MOLECULES; PHOSPHORYLATION; TRANSCRIPTION FACTORS;

CELL DEATH;

ANTIBODY; BIM ANTIBODY; BIM PROTEIN; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING AFFINITY; BINDING SITE; BREAST CANCER; CANCER CELL; CELL ADHESION; CELL MIGRATION; CELL SHAPE; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; CYTOSKELETON; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; UPREGULATION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; E2F1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICROTUBULES; MITOCHONDRIA; NEOPLASMS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84872093149     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.386102     Document Type: Article

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