Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim

Journal of Experimental Medicine

Volumn 196, Issue 7, 2002, Pages 947-955

  Davey, Gayle M ^a   Kurts, Christian ^b   Miller, Jacques F A P ^a   Bouillet, Philippe ^a   Strasser, Andreas ^a   Brooks, Andrew G ^c   Carbone, Francis R ^a,c   Heath, William R ^a  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Antigen presentation; Apoptosis; Bcl 2; CD8 positive T lymphocytes; T cell tolerance

Indexed keywords

APOPTOSIS INDUCING FACTOR; AUTOANTIGEN; BIM PROTEIN; CD8 ANTIGEN; OVALBUMIN; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CONTROLLED STUDY; CROSS REACTION; CROSS TOLERANCE; DENDRITIC CELL; GENE OVEREXPRESSION; IMMUNOLOGICAL TOLERANCE; LYMPH NODE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMOCYTE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOANTIGENS; CARRIER PROTEINS; CD8-POSITIVE T-LYMPHOCYTES; INSULIN; LYMPHOCYTE DEPLETION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OVALBUMIN; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 0037037543     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20020827     Document Type: Article

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