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Volumn 6, Issue 6, 2012, Pages 457-470

The dual roles of homeobox genes in vascularization and wound healing

Author keywords

Angiogenesis; Endothelial cells; Hox genes; Inflammation; Tumor vascularization

Indexed keywords

HOMEODOMAIN PROTEIN;

EID: 84872063817     PISSN: 19336918     EISSN: 19336926     Source Type: Journal    
DOI: 10.4161/cam.22164     Document Type: Review
Times cited : (63)

References (146)
  • 1
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • PMID:11001068
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000; 407:249-57; PMID:11001068; http://dx.doi.org/10.1038/35025220
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 2
    • 13944255075 scopus 로고    scopus 로고
    • Mathematical model of oxygen distribution in engineered cardiac tissue with parallel channel array perfused with culture medium containing oxygen carriers
    • PMID:15539422
    • Radisic M, Deen W, Langer R, Vunjak-Novakovic G. Mathematical model of oxygen distribution in engineered cardiac tissue with parallel channel array perfused with culture medium containing oxygen carriers. Am J Physiol Heart Circ Physiol 2005; 288: H1278-89; PMID:15539422; http://dx.doi.org/10.1152/ajpheart. 00787.2004
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Radisic, M.1    Deen, W.2    Langer, R.3    Vunjak-Novakovic, G.4
  • 3
    • 0034470341 scopus 로고    scopus 로고
    • Vasculogenesis and angiogenesis as mechanisms of vascular network formation, growth and remodeling
    • PMID: 11245270
    • Patan S. Vasculogenesis and angiogenesis as mechanisms of vascular network formation, growth and remodeling. J Neurooncol 2000; 50:1-15; PMID: 11245270; http://dx.doi.org/10.1023/A:1006493130855
    • (2000) J Neurooncol , vol.50 , pp. 1-15
    • Patan, S.1
  • 4
    • 0032215354 scopus 로고    scopus 로고
    • VEGF gene delivery to muscle: Potential role for vasculogenesis in adults
    • PMID:9844628
    • Springer ML, Chen AS, Kraft PE, Bednarski M, Blau HM. VEGF gene delivery to muscle: potential role for vasculogenesis in adults. Mol Cell 1998; 2:549-58; PMID:9844628; http://dx.doi.org/10.1016/S1097-2765(00)80154-9
    • (1998) Mol Cell , vol.2 , pp. 549-558
    • Springer, M.L.1    Chen, A.S.2    Kraft, P.E.3    Bednarski, M.4    Blau, H.M.5
  • 5
    • 0033529618 scopus 로고    scopus 로고
    • Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization
    • PMID:10436164
    • Asahara T, Masuda H, Takahashi T, Kalka C, Pastore C, Silver M, et al. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 1999; 85:221-8; PMID:10436164; http://dx.doi.org/10.1161/01.RES.85.3.221
    • (1999) Circ Res , vol.85 , pp. 221-228
    • Asahara, T.1    Masuda, H.2    Takahashi, T.3    Kalka, C.4    Pastore, C.5    Silver, M.6
  • 6
    • 42949175181 scopus 로고    scopus 로고
    • Matrix metalloproteinase control of capillary morphogenesis
    • PMID: 18540825
    • Ghajar CM, George SC, Putnam AJ. Matrix metalloproteinase control of capillary morphogenesis. Crit Rev Eukaryot Gene Expr 2008; 18:251-78; PMID: 18540825; http://dx.doi.org/10.1615/CritRevEukarGeneExpr.v18.i3.30
    • (2008) Crit Rev Eukaryot Gene Expr , vol.18 , pp. 251-278
    • Ghajar, C.M.1    George, S.C.2    Putnam, A.J.3
  • 7
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • PMID:7584949
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995; 1:27-31; PMID:7584949; http://dx.doi.org/10.1038/nm0195- 27
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 8
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • PMID:8756718
    • Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86:353-64; PMID:8756718; http://dx.doi.org/10.1016/S0092-8674(00)80108-7
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 9
    • 0026362940 scopus 로고
    • Switch to the angiogenic phenotype during tumorigenesis
    • PMID:1726933
    • Folkman J, Hanahan D. Switch to the angiogenic phenotype during tumorigenesis. Princess Takamatsu Symp 1991; 22:339-47; PMID:1726933
    • (1991) Princess Takamatsu Symp , vol.22 , pp. 339-347
    • Folkman, J.1    Hanahan, D.2
  • 10
    • 63149088164 scopus 로고    scopus 로고
    • Trophic macrophages in development and disease
    • PMID:19282852
    • Pollard JW. Trophic macrophages in development and disease. Nat Rev Immunol 2009; 9:259-70; PMID:19282852; http://dx.doi.org/10.1038/nri2528
    • (2009) Nat Rev Immunol , vol.9 , pp. 259-270
    • Pollard, J.W.1
  • 11
    • 58149267580 scopus 로고    scopus 로고
    • Corrupt policemen: Inflammatory cells promote tumor angiogenesis
    • PMID:19125020
    • Zumsteg A, Christofori G. Corrupt policemen: inflammatory cells promote tumor angiogenesis. Curr Opin Oncol 2009; 21:60-70; PMID:19125020; http://dx.doi.org/10.1097/CCO.0b013e32831bed7e
    • (2009) Curr Opin Oncol , vol.21 , pp. 60-70
    • Zumsteg, A.1    Christofori, G.2
  • 12
    • 0005339099 scopus 로고    scopus 로고
    • Tumor-associated macrophages in breast cancer
    • PMID:12463738
    • Leek RD, Harris AL. Tumor-associated macrophages in breast cancer. J Mammary Gland Biol Neoplasia 2002; 7:177-89; PMID:12463738; http://dx.doi.org/ 10.1023/A:1020304003704
    • (2002) J Mammary Gland Biol Neoplasia , vol.7 , pp. 177-189
    • Leek, R.D.1    Harris, A.L.2
  • 13
    • 33845767868 scopus 로고    scopus 로고
    • Macrophages regulate the angiogenic switch in a mouse model of breast cancer
    • PMID:17114237
    • Lin EY, Li JF, Gnatovskiy L, Deng Y, Zhu L, Grzesik DA, et al. Macrophages regulate the angiogenic switch in a mouse model of breast cancer. Cancer Res 2006; 66:11238-46; PMID:17114237; http://dx.doi.org/10.1158/0008- 5472.CAN-06-1278
    • (2006) Cancer Res , vol.66 , pp. 11238-11246
    • Lin, E.Y.1    Li, J.F.2    Gnatovskiy, L.3    Deng, Y.4    Zhu, L.5    Grzesik, D.A.6
  • 14
    • 4944239035 scopus 로고    scopus 로고
    • An aminobisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis
    • PMID:15343380
    • Giraudo E, Inoue M, Hanahan D. An aminobisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis. J Clin Invest 2004; 114:623-33; PMID:15343380
    • (2004) J Clin Invest , vol.114 , pp. 623-633
    • Giraudo, E.1    Inoue, M.2    Hanahan, D.3
  • 15
    • 39849102836 scopus 로고    scopus 로고
    • HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion
    • PMID:18328425
    • Du R, Lu KV, Petritsch C, Liu P, Ganss R, Passegué E, et al. HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell 2008; 13:206-20; PMID:18328425; http://dx.doi.org/10.1016/j.ccr.2008.01.034
    • (2008) Cancer Cell , vol.13 , pp. 206-220
    • Du, R.1    Lu, K.V.2    Petritsch, C.3    Liu, P.4    Ganss, R.5    Passegué, E.6
  • 16
    • 66049154097 scopus 로고    scopus 로고
    • M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis
    • PMID:19398755
    • Kubota Y, Takubo K, Shimizu T, Ohno H, Kishi K, Shibuya M, et al. M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med 2009; 206:1089-102; PMID:19398755; http://dx.doi.org/10.1084/jem. 20081605
    • (2009) J Exp Med , vol.206 , pp. 1089-1102
    • Kubota, Y.1    Takubo, K.2    Shimizu, T.3    Ohno, H.4    Kishi, K.5    Shibuya, M.6
  • 17
    • 33746926292 scopus 로고    scopus 로고
    • Clodronate-liposome-mediated depletion of tumour-associated macrophages: A new and highly effective antiangiogenic therapy approach
    • PMID:16832418
    • Zeisberger SM, Odermatt B, Marty C, Zehnder-Fjällman AH, Ballmer-Hofer K, Schwendener RA. Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach. Br J Cancer 2006; 95:272-81; PMID:16832418; http://dx.doi.org/10. 1038/sj.bjc.6603240
    • (2006) Br J Cancer , vol.95 , pp. 272-281
    • Zeisberger, S.M.1    Odermatt, B.2    Marty, C.3    Zehnder-Fjällman, A.H.4    Ballmer-Hofer, K.5    Schwendener, R.A.6
  • 18
    • 0025147371 scopus 로고
    • A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
    • PMID:1697685
    • Good DJ, Polverini PJ, Rastinejad F, Le Beau MM, Lemons RS, Frazier WA, et al. A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc Natl Acad Sci U S A 1990; 87:6624-8; PMID:1697685; http://dx.doi.org/10.1073/pnas. 87.17.6624
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 6624-6628
    • Good, D.J.1    Polverini, P.J.2    Rastinejad, F.3    Le Beau, M.M.4    Lemons, R.S.5    Frazier, W.A.6
  • 19
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • PMID:7521539
    • Dameron KM, Volpert OV, Tainsky MA, Bouck N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 1994; 265:1582-4; PMID:7521539; http://dx.doi.org/10.1126/science.7521539
    • (1994) Science , vol.265 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 20
    • 0036899023 scopus 로고    scopus 로고
    • Sustained expression of homeobox D10 inhibits angiogenesis
    • PMID:12466126
    • Myers C, Charboneau A, Cheung I, Hanks D, Boudreau N. Sustained expression of homeobox D10 inhibits angiogenesis. Am J Pathol 2002; 161:2099-109; PMID:12466126; http://dx.doi.org/10.1016/S0002-9440(10)64488-4
    • (2002) Am J Pathol , vol.161 , pp. 2099-2109
    • Myers, C.1    Charboneau, A.2    Cheung, I.3    Hanks, D.4    Boudreau, N.5
  • 22
    • 0018240421 scopus 로고
    • A gene complex controlling segmentation in Drosophila
    • PMID:103000
    • Lewis EB. A gene complex controlling segmentation in Drosophila. Nature 1978; 276:565-70; PMID:103000; http://dx.doi.org/10.1038/276565a0
    • (1978) Nature , vol.276 , pp. 565-570
    • Lewis, E.B.1
  • 23
    • 0027953771 scopus 로고
    • Hox genes in vertebrate development
    • PMID:7913880
    • Krumlauf R. Hox genes in vertebrate development. Cell 1994; 78:191-201; PMID:7913880; http://dx.doi.org/10.1016/0092-8674(94)90290-9
    • (1994) Cell , vol.78 , pp. 191-201
    • Krumlauf, R.1
  • 24
    • 67749093008 scopus 로고    scopus 로고
    • Hox genes and vertebrate axial pattern
    • PMID:19651308
    • Wellik DM. Hox genes and vertebrate axial pattern. Curr Top Dev Biol 2009; 88:257-78; PMID:19651308; http://dx.doi.org/10.1016/S0070-2153(09)88009-5
    • (2009) Curr Top Dev Biol , vol.88 , pp. 257-278
    • Wellik, D.M.1
  • 25
    • 0026497470 scopus 로고
    • Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene
    • PMID:1359423
    • Lufkin T, Mark M, Hart CP, Dollé P, LeMeur M, Chambon P. Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene. Nature 1992; 359:835-41; PMID:1359423; http://dx.doi.org/10.1038/ 359835a0
    • (1992) Nature , vol.359 , pp. 835-841
    • Lufkin, T.1    Mark, M.2    Hart, C.P.3    Dollé, P.4    LeMeur, M.5    Chambon, P.6
  • 26
    • 0025342695 scopus 로고
    • Variations of cervical vertebrae after expression of a Hox-1.1 transgene in mice
    • PMID:1970515
    • Kessel M, Balling R, Gruss P. Variations of cervical vertebrae after expression of a Hox-1.1 transgene in mice. Cell 1990; 61:301-8; PMID:1970515; http://dx.doi.org/10.1016/0092-8674(90)90810-2
    • (1990) Cell , vol.61 , pp. 301-308
    • Kessel, M.1    Balling, R.2    Gruss, P.3
  • 27
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • International Human Genome Sequencing Consortium PMID:11237011
    • Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, et al. International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 2001; 409:860-921; PMID:11237011; http://dx.doi.org/10.1038/35057062
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3    Nusbaum, C.4    Zody, M.C.5    Baldwin, J.6
  • 28
    • 0026504525 scopus 로고
    • Homeobox genes and axial patterning
    • PMID:1346368
    • McGinnis W, Krumlauf R. Homeobox genes and axial patterning. Cell 1992; 68:283-302; PMID:1346368; http://dx.doi.org/10.1016/0092-8674(92)90471-N
    • (1992) Cell , vol.68 , pp. 283-302
    • McGinnis, W.1    Krumlauf, R.2
  • 29
    • 0028124772 scopus 로고
    • Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions
    • PMID:7913519
    • Condie BG, Capecchi MR. Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions. Nature 1994; 370: 304-7; PMID:7913519; http://dx.doi.org/10.1038/370304a0
    • (1994) Nature , vol.370 , pp. 304-307
    • Condie, B.G.1    Capecchi, M.R.2
  • 30
    • 0029026767 scopus 로고
    • Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11
    • PMID:7596412
    • Davis AP, Witte DP, Hsieh-Li HM, Potter SS, Capecchi MR. Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11. Nature 1995; 375:791-5; PMID:7596412; http://dx.doi.org/10.1038/375791a0
    • (1995) Nature , vol.375 , pp. 791-795
    • Davis, A.P.1    Witte, D.P.2    Hsieh-Li, H.M.3    Potter, S.S.4    Capecchi, M.R.5
  • 31
    • 0029143166 scopus 로고
    • Compound mutants for the paralogous hoxa-4, hoxb-4, and hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed
    • PMID:7628700
    • Horan GS, Ramírez-Solis R, Featherstone MS, Wolgemuth DJ, Bradley A, Behringer RR. Compound mutants for the paralogous hoxa-4, hoxb-4, and hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed. Genes Dev 1995; 9:1667-77; PMID:7628700; http://dx.doi.org/10.1101/gad.9.13.1667
    • (1995) Genes Dev , vol.9 , pp. 1667-1677
    • Horan, G.S.1    Ramírez-Solis, R.2    Featherstone, M.S.3    Wolgemuth, D.J.4    Bradley, A.5    Behringer, R.R.6
  • 32
    • 0029045063 scopus 로고
    • Mutations in paralogous Hox genes result in overlapping homeotic transformations of the axial skeleton: Evidence for unique and redundant function
    • PMID:7750651
    • Horan GS, Kovàcs EN, Behringer RR, Featherstone MS. Mutations in paralogous Hox genes result in overlapping homeotic transformations of the axial skeleton: evidence for unique and redundant function. Dev Biol 1995; 169:359-72; PMID:7750651; http://dx.doi.org/10.1006/dbio.1995.1150
    • (1995) Dev Biol , vol.169 , pp. 359-372
    • Horan, G.S.1    Kovàcs, E.N.2    Behringer, R.R.3    Featherstone, M.S.4
  • 33
    • 0030040552 scopus 로고    scopus 로고
    • Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning
    • PMID:8625797
    • Fromental-Ramain C, Warot X, Lakkaraju S, Favier B, Haack H, Birling C, et al. Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning. Development 1996; 122:461-72; PMID:8625797
    • (1996) Development , vol.122 , pp. 461-472
    • Fromental-Ramain, C.1    Warot, X.2    Lakkaraju, S.3    Favier, B.4    Haack, H.5    Birling, C.6
  • 34
    • 0034628489 scopus 로고    scopus 로고
    • Maintenance of functional equivalence during paralogous Hox gene evolution
    • PMID:10688203
    • Greer JM, Puetz J, Thomas KR, Capecchi MR. Maintenance of functional equivalence during paralogous Hox gene evolution. Nature 2000; 403:661-5; PMID:10688203; http://dx.doi.org/10.1038/35001077
    • (2000) Nature , vol.403 , pp. 661-665
    • Greer, J.M.1    Puetz, J.2    Thomas, K.R.3    Capecchi, M.R.4
  • 35
    • 0029963585 scopus 로고    scopus 로고
    • A mutational analysis of the 5′ HoxD genes: Dissection of genetic interactions during limb development in the mouse
    • PMID:8620844
    • Davis AP, Capecchi MR. A mutational analysis of the 5′ HoxD genes: dissection of genetic interactions during limb development in the mouse. Development 1996; 122:1175-85; PMID:8620844
    • (1996) Development , vol.122 , pp. 1175-1185
    • Davis, A.P.1    Capecchi, M.R.2
  • 36
    • 0033572530 scopus 로고    scopus 로고
    • Targeted disruption of Hoxd9 and Hoxd10 alters locomotor behavior, vertebral identity, and peripheral nervous system development
    • PMID:10642795
    • de la Cruz CC, Der-Avakian A, Spyropoulos DD, Tieu DD, Carpenter EM. Targeted disruption of Hoxd9 and Hoxd10 alters locomotor behavior, vertebral identity, and peripheral nervous system development. Dev Biol 1999; 216:595-610; PMID:10642795; http://dx.doi.org/10.1006/dbio.1999.9528
    • (1999) Dev Biol , vol.216 , pp. 595-610
    • De La Cruz, C.C.1    Der-Avakian, A.2    Spyropoulos, D.D.3    Tieu, D.D.4    Carpenter, E.M.5
  • 37
    • 0028859990 scopus 로고
    • Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation
    • PMID:7828847
    • Rancourt DE, Tsuzuki T, Capecchi MR. Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation. Genes Dev 1995; 9: 108-22; PMID:7828847; http://dx.doi.org/10.1101/gad.9.1.108
    • (1995) Genes Dev , vol.9 , pp. 108-122
    • Rancourt, D.E.1    Tsuzuki, T.2    Capecchi, M.R.3
  • 38
    • 0030019608 scopus 로고    scopus 로고
    • Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton
    • PMID:8625796
    • Favier B, Rijli FM, Fromental-Ramain C, Fraulob V, Chambon P, Dollé P. Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton. Development 1996; 122:449-60; PMID:8625796
    • (1996) Development , vol.122 , pp. 449-460
    • Favier, B.1    Rijli, F.M.2    Fromental-Ramain, C.3    Fraulob, V.4    Chambon, P.5    Dollé, P.6
  • 39
    • 0025797513 scopus 로고
    • Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5
    • PMID:1673020
    • Chisaka O, Capecchi MR. Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5. Nature 1991; 350:473-9; PMID:1673020; http://dx.doi.org/10.1038/350473a0
    • (1991) Nature , vol.350 , pp. 473-479
    • Chisaka, O.1    Capecchi, M.R.2
  • 40
    • 0034004138 scopus 로고    scopus 로고
    • Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus
    • PMID:10664157
    • Bergwerff M, Gittenberger-de Groot AC, Wisse LJ, DeRuiter MC, Wessels A, Martin JF, et al. Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus. Virchows Arch 2000; 436:12-9; PMID:10664157; http://dx.doi.org/10.1007/PL00008193
    • (2000) Virchows Arch , vol.436 , pp. 12-19
    • Bergwerff, M.1    Gittenberger-de Groot, A.C.2    Wisse, L.J.3    DeRuiter, M.C.4    Wessels, A.5    Martin, J.F.6
  • 41
    • 0030071340 scopus 로고    scopus 로고
    • Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells
    • PMID:8570656
    • Miano JM, Firulli AB, Olson EN, Hara P, Giachelli CM, Schwartz SM. Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells. Proc Natl Acad Sci U S A 1996; 93:900-5; PMID:8570656; http://dx.doi.org/10.1073/pnas.93.2.900
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 900-905
    • Miano, J.M.1    Firulli, A.B.2    Olson, E.N.3    Hara, P.4    Giachelli, C.M.5    Schwartz, S.M.6
  • 42
    • 0043133832 scopus 로고    scopus 로고
    • HoxB5 is an upstream transcriptional switch for differentiation of the vascular endothelium from precursor cells
    • PMID:12897140
    • Wu Y, Moser M, Bautch VL, Patterson C. HoxB5 is an upstream transcriptional switch for differentiation of the vascular endothelium from precursor cells. Mol Cell Biol 2003; 23:5680-91; PMID:12897140; http://dx.doi.org/10.1128/MCB.23.16.5680-5691.2003
    • (2003) Mol Cell Biol , vol.23 , pp. 5680-5691
    • Wu, Y.1    Moser, M.2    Bautch, V.L.3    Patterson, C.4
  • 43
    • 79952341940 scopus 로고    scopus 로고
    • Temporal changes in Hox gene expression accompany endothelial cell differentiation of embryonic stem cells
    • PMID:21200152
    • Bahrami SB, Veiseh M, Dunn AA, Boudreau NJ. Temporal changes in Hox gene expression accompany endothelial cell differentiation of embryonic stem cells. Cell Adh Migr 2011; 5:133-41; PMID:21200152; http://dx.doi.org/10.4161/cam.5.2. 14373
    • (2011) Cell Adh Migr , vol.5 , pp. 133-141
    • Bahrami, S.B.1    Veiseh, M.2    Dunn, A.A.3    Boudreau, N.J.4
  • 44
    • 78650516843 scopus 로고    scopus 로고
    • HoxA3 is an apical regulator of haemogenic endothelium
    • PMID:21170035
    • Iacovino M, Chong D, Szatmari I, Hartweck L, Rux D, Caprioli A, et al. HoxA3 is an apical regulator of haemogenic endothelium. Nat Cell Biol 2011; 13:72-8; PMID:21170035; http://dx.doi.org/10.1038/ncb2137
    • (2011) Nat Cell Biol , vol.13 , pp. 72-78
    • Iacovino, M.1    Chong, D.2    Szatmari, I.3    Hartweck, L.4    Rux, D.5    Caprioli, A.6
  • 45
    • 22344439276 scopus 로고    scopus 로고
    • Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells
    • PMID:15928198
    • Rössig L, Urbich C, Brühl T, Dernbach E, Heeschen C, Chavakis E, et al. Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells. J Exp Med 2005; 201:1825-35; PMID:15928198; http://dx.doi.org/10.1084/jem.20042097
    • (2005) J Exp Med , vol.201 , pp. 1825-1835
    • Rössig, L.1    Urbich, C.2    Brühl, T.3    Dernbach, E.4    Heeschen, C.5    Chavakis, E.6
  • 46
    • 0026462854 scopus 로고
    • Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells
    • PMID:1360645
    • Crompton MR, Bartlett TJ, MacGregor AD, Manfioletti G, Buratti E, Giancotti V, et al. Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells. Nucleic Acids Res 1992; 20:5661-7; PMID:1360645; http://dx.doi.org/10.1093/nar/20.21.5661
    • (1992) Nucleic Acids Res , vol.20 , pp. 5661-5667
    • Crompton, M.R.1    Bartlett, T.J.2    MacGregor, A.D.3    Manfioletti, G.4    Buratti, E.5    Giancotti, V.6
  • 47
    • 8444234265 scopus 로고    scopus 로고
    • A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels
    • PMID:15459110
    • Hallaq H, Pinter E, Enciso J, McGrath J, Zeiss C, Brueckner M, et al. A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels. Development 2004; 131: 5197-209; PMID:15459110; http://dx.doi.org/10.1242/dev.01393
    • (2004) Development , vol.131 , pp. 5197-5209
    • Hallaq, H.1    Pinter, E.2    Enciso, J.3    McGrath, J.4    Zeiss, C.5    Brueckner, M.6
  • 48
    • 0037327001 scopus 로고    scopus 로고
    • HEX acts as a negative regulator of angiogenesis by modulating the expression of angiogenesis-related gene in endothelial cells in vitro
    • PMID:12588764
    • Nakagawa T, Abe M, Yamazaki T, Miyashita H, Niwa H, Kokubun S, et al. HEX acts as a negative regulator of angiogenesis by modulating the expression of angiogenesis-related gene in endothelial cells in vitro. Arterioscler Thromb Vasc Biol 2003; 23:231-7; PMID:12588764; http://dx.doi.org/10.1161/01.ATV. 0000052670.55321.87
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 231-237
    • Nakagawa, T.1    Abe, M.2    Yamazaki, T.3    Miyashita, H.4    Niwa, H.5    Kokubun, S.6
  • 49
    • 2442646336 scopus 로고    scopus 로고
    • Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling
    • PMID:15016828
    • Minami T, Murakami T, Horiuchi K, Miura M, Noguchi T, Miyazaki J, et al. Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling. J Biol Chem 2004; 279: 20626-35; PMID:15016828; http://dx.doi.org/10.1074/jbc. M308730200
    • (2004) J Biol Chem , vol.279 , pp. 20626-20635
    • Minami, T.1    Murakami, T.2    Horiuchi, K.3    Miura, M.4    Noguchi, T.5    Miyazaki, J.6
  • 50
    • 0030762078 scopus 로고    scopus 로고
    • Induction of the angiogenic phenotype by Hox D3
    • PMID:9314544
    • Boudreau N, Andrews C, Srebrow A, Ravanpay A, Cheresh DA. Induction of the angiogenic phenotype by Hox D3. J Cell Biol 1997; 139:257-64; PMID:9314544; http://dx.doi.org/10.1083/jcb.139.1.257
    • (1997) J Cell Biol , vol.139 , pp. 257-264
    • Boudreau, N.1    Andrews, C.2    Srebrow, A.3    Ravanpay, A.4    Cheresh, D.A.5
  • 51
    • 1042301376 scopus 로고    scopus 로고
    • The homeobox transcription factor Hox D3 promotes integrin alpha5beta1 expression and function during angiogenesis
    • PMID:14610084
    • Boudreau NJ, Varner JA. The homeobox transcription factor Hox D3 promotes integrin alpha5beta1 expression and function during angiogenesis. J Biol Chem 2004; 279:4862-8; PMID:14610084; http://dx.doi.org/10.1074/jbc.M305190200
    • (2004) J Biol Chem , vol.279 , pp. 4862-4868
    • Boudreau, N.J.1    Varner, J.A.2
  • 52
    • 33644606996 scopus 로고    scopus 로고
    • Pbx1 is required for Hox D3-mediated angiogenesis
    • PMID:16328158
    • Charboneau A, East L, Mulholland N, Rohde M, Boudreau N. Pbx1 is required for Hox D3-mediated angiogenesis. Angiogenesis 2005; 8:289-96; PMID:16328158; http://dx.doi.org/10.1007/s10456-005-9016-7
    • (2005) Angiogenesis , vol.8 , pp. 289-296
    • Charboneau, A.1    East, L.2    Mulholland, N.3    Rohde, M.4    Boudreau, N.5
  • 53
    • 79955381485 scopus 로고    scopus 로고
    • Homeobox D1 regulates angiogenic functions of endothelial cells via integrin â1 expression
    • PMID:21501586
    • Park H, Choi HJ, Kim J, Kim M, Rho SS, Hwang D, et al. Homeobox D1 regulates angiogenic functions of endothelial cells via integrin â1 expression. Biochem Biophys Res Commun 2011; 408:186-92; PMID:21501586; http://dx.doi.org/10.1016/j.bbrc.2011.04.017
    • (2011) Biochem Biophys Res Commun , vol.408 , pp. 186-192
    • Park, H.1    Choi, H.J.2    Kim, J.3    Kim, M.4    Rho, S.S.5    Hwang, D.6
  • 54
    • 0028362876 scopus 로고
    • Requirement of vascular integrin alpha v beta 3 for angiogenesis
    • PMID:7512751
    • Brooks PC, Clark RA, Cheresh DA. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 1994; 264:569-71; PMID:7512751; http://dx.doi.org/10.1126/science.7512751
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 55
    • 0033843942 scopus 로고    scopus 로고
    • Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin
    • PMID:10751360
    • Kim S, Bell K, Mousa SA, Varner JA. Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin. Am J Pathol 2000; 156:1345-62; PMID:10751360; http://dx.doi.org/10. 1016/S0002-9440(10)65005-5
    • (2000) Am J Pathol , vol.156 , pp. 1345-1362
    • Kim, S.1    Bell, K.2    Mousa, S.A.3    Varner, J.A.4
  • 56
    • 21644472188 scopus 로고    scopus 로고
    • HOXA3 induces cell migration in endothelial and epithelial cells promoting angiogenesis and wound repair
    • PMID:15914537
    • Mace KA, Hansen SL, Myers C, Young DM, Boudreau N. HOXA3 induces cell migration in endothelial and epithelial cells promoting angiogenesis and wound repair. J Cell Sci 2005; 118:2567-77; PMID:15914537; http://dx.doi.org/10.1242/ jcs.02399
    • (2005) J Cell Sci , vol.118 , pp. 2567-2577
    • Mace, K.A.1    Hansen, S.L.2    Myers, C.3    Young, D.M.4    Boudreau, N.5
  • 57
    • 0034707595 scopus 로고    scopus 로고
    • Homeobox B3 promotes capillary morphogenesis and angiogenesis
    • PMID:10648567
    • Myers C, Charboneau A, Boudreau N. Homeobox B3 promotes capillary morphogenesis and angiogenesis. J Cell Biol 2000; 148:343-51; PMID:10648567; http://dx.doi.org/10.1083/jcb.148.2.343
    • (2000) J Cell Biol , vol.148 , pp. 343-351
    • Myers, C.1    Charboneau, A.2    Boudreau, N.3
  • 58
    • 0344413014 scopus 로고    scopus 로고
    • HoxD3 accelerates wound healing in diabetic mice
    • PMID:14633614
    • Hansen SL, Myers CA, Charboneau A, Young DM, Boudreau N. HoxD3 accelerates wound healing in diabetic mice. Am J Pathol 2003; 163:2421-31; PMID:14633614; http://dx.doi.org/10.1016/S0002-9440(10)63597-3
    • (2003) Am J Pathol , vol.163 , pp. 2421-2431
    • Hansen, S.L.1    Myers, C.A.2    Charboneau, A.3    Young, D.M.4    Boudreau, N.5
  • 59
    • 0033556313 scopus 로고    scopus 로고
    • Endothelial cells express a novel, tumor necrosis factor-alpha-regulated variant of HOXA9
    • PMID:9880515
    • Patel CV, Sharangpani R, Bandyopadhyay S, DiCorleto PE. Endothelial cells express a novel, tumor necrosis factor-alpha-regulated variant of HOXA9. J Biol Chem 1999; 274:1415-22; PMID:9880515; http://dx.doi.org/10.1074/jbc.274.3.1415
    • (1999) J Biol Chem , vol.274 , pp. 1415-1422
    • Patel, C.V.1    Sharangpani, R.2    Bandyopadhyay, S.3    DiCorleto, P.E.4
  • 60
    • 1842559902 scopus 로고    scopus 로고
    • Homeobox A9 transcriptionally regulates the EphB4 receptor to modulate endothelial cell migration and tube formation
    • PMID:14764452
    • Bruhl T, Urbich C, Aicher D, Acker-Palmer A, Zeiher AM, Dimmeler S. Homeobox A9 transcriptionally regulates the EphB4 receptor to modulate endothelial cell migration and tube formation. Circ Res 2004; 94: 743-51; PMID:14764452; http://dx.doi.org/10.1161/01.RES.0000120861.27064.09
    • (2004) Circ Res , vol.94 , pp. 743-751
    • Bruhl, T.1    Urbich, C.2    Aicher, D.3    Acker-Palmer, A.4    Zeiher, A.M.5    Dimmeler, S.6
  • 61
    • 69249110820 scopus 로고    scopus 로고
    • Endothelial cell migration and vascular endothelial growth factor expression are the result of loss of breast tissue polarity
    • PMID:19654314
    • Chen A, Cuevas I, Kenny PA, Miyake H, Mace K, Ghajar C, et al. Endothelial cell migration and vascular endothelial growth factor expression are the result of loss of breast tissue polarity. Cancer Res 2009; 69: 6721-9; PMID:19654314; http://dx.doi.org/10.1158/0008-5472.CAN-08-4069
    • (2009) Cancer Res , vol.69 , pp. 6721-6729
    • Chen, A.1    Cuevas, I.2    Kenny, P.A.3    Miyake, H.4    Mace, K.5    Ghajar, C.6
  • 62
    • 30944466045 scopus 로고    scopus 로고
    • A role for Hox A5 in regulating angiogenesis and vascular patterning
    • PMID:16379594
    • Rhoads K, Arderiu G, Charboneau A, Hansen SL, Hoffman W, Boudreau N. A role for Hox A5 in regulating angiogenesis and vascular patterning. Lymphat Res Biol 2005; 3:240-52; PMID:16379594; http://dx.doi.org/10.1089/lrb.2005.3.240
    • (2005) Lymphat Res Biol , vol.3 , pp. 240-252
    • Rhoads, K.1    Arderiu, G.2    Charboneau, A.3    Hansen, S.L.4    Hoffman, W.5    Boudreau, N.6
  • 63
    • 66549118591 scopus 로고    scopus 로고
    • HoxA5 stabilizes adherens junctions via increased Akt1
    • PMID:19262140
    • Arderiu G, Cuevas I, Chen A, Carrio M, East L, Boudreau NJ. HoxA5 stabilizes adherens junctions via increased Akt1. Cell Adh Migr 2007; 1:185-95; PMID:19262140; http://dx.doi.org/10.4161/cam.1.4.5448
    • (2007) Cell Adh Migr , vol.1 , pp. 185-195
    • Arderiu, G.1    Cuevas, I.2    Chen, A.3    Carrio, M.4    East, L.5    Boudreau, N.J.6
  • 64
    • 67651123069 scopus 로고    scopus 로고
    • HoxB5 induces endothelial sprouting in vitro and modifies intussusceptive angiogenesis in vivo involving angiopoietin-2
    • PMID:19403561
    • Winnik S, Klinkert M, Kurz H, Zoeller C, Heinke J, Wu Y, et al. HoxB5 induces endothelial sprouting in vitro and modifies intussusceptive angiogenesis in vivo involving angiopoietin-2. Cardiovasc Res 2009; 83: 558-65; PMID:19403561; http://dx.doi.org/10.1093/cvr/cvp133
    • (2009) Cardiovasc Res , vol.83 , pp. 558-565
    • Winnik, S.1    Klinkert, M.2    Kurz, H.3    Zoeller, C.4    Heinke, J.5    Wu, Y.6
  • 65
    • 0027256035 scopus 로고
    • Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells
    • PMID:8098844
    • Gorski DH, LePage DF, Patel CV, Copeland NG, Jenkins NA, Walsh K. Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells. Mol Cell Biol 1993; 13:3722-33; PMID:8098844
    • (1993) Mol Cell Biol , vol.13 , pp. 3722-3733
    • Gorski, D.H.1    LePage, D.F.2    Patel, C.V.3    Copeland, N.G.4    Jenkins, N.A.5    Walsh, K.6
  • 66
    • 0030610836 scopus 로고    scopus 로고
    • p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene
    • PMID:9224717
    • Smith RC, Branellec D, Gorski DH, Guo K, Perlman H, Dedieu JF, et al. p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene. Genes Dev 1997; 11:1674-89; PMID:9224717; http://dx.doi.org/ 10.1101/gad.11.13.1674
    • (1997) Genes Dev , vol.11 , pp. 1674-1689
    • Smith, R.C.1    Branellec, D.2    Gorski, D.H.3    Guo, K.4    Perlman, H.5    Dedieu, J.F.6
  • 67
    • 0037709253 scopus 로고    scopus 로고
    • Inhibition of endothelial cell activation by the homeobox gene Gax
    • PMID:12842453
    • Gorski DH, Leal AJ. Inhibition of endothelial cell activation by the homeobox gene Gax. J Surg Res 2003; 111:91-9; PMID:12842453; http://dx.doi.org/10.1016/S0022-4804(03)00042-8
    • (2003) J Surg Res , vol.111 , pp. 91-99
    • Gorski, D.H.1    Leal, A.J.2
  • 68
    • 83755228645 scopus 로고    scopus 로고
    • Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells
    • PMID:22206000
    • Douville JM, Cheung DY, Herbert KL, Moffatt T, Wigle JT. Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells. PLoS One 2011; 6:e29099; PMID:22206000; http://dx.doi.org/10.1371/journal.pone.0029099
    • (2011) PLoS One , vol.6
    • Douville, J.M.1    Cheung, D.Y.2    Herbert, K.L.3    Moffatt, T.4    Wigle, J.T.5
  • 69
    • 13944268747 scopus 로고    scopus 로고
    • The homeobox gene Gax inhibits angiogenesis through inhibition of nuclear factor-kappaB-dependent endothelial cell gene expression
    • PMID:15735029
    • Patel S, Leal AD, Gorski DH. The homeobox gene Gax inhibits angiogenesis through inhibition of nuclear factor-kappaB-dependent endothelial cell gene expression. Cancer Res 2005; 65:1414-24; PMID:15735029; http://dx.doi.org/10. 1158/0008-5472.CAN-04-3431
    • (2005) Cancer Res , vol.65 , pp. 1414-1424
    • Patel, S.1    Leal, A.D.2    Gorski, D.H.3
  • 70
    • 38949193234 scopus 로고    scopus 로고
    • Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5
    • PMID:17957028
    • Chen Y, Gorski DH. Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood 2008; 111:1217-26; PMID:17957028; http://dx.doi.org/10.1182/blood-2007-07- 104133
    • (2008) Blood , vol.111 , pp. 1217-1226
    • Chen, Y.1    Gorski, D.H.2
  • 71
    • 0033517356 scopus 로고    scopus 로고
    • Cutaneous wound healing
    • PMID:10471461
    • Singer AJ, Clark RA. Cutaneous wound healing. N Engl J Med 1999; 341:738-46; PMID:10471461; http://dx.doi.org/10.1056/NEJM199909023411006
    • (1999) N Engl J Med , vol.341 , pp. 738-746
    • Singer, A.J.1    Clark, R.A.2
  • 73
    • 68049144398 scopus 로고    scopus 로고
    • HOXA3 modulates injuryinduced mobilization and recruitment of bone marrow-derived cells
    • PMID:19544454
    • Mace KA, Restivo TE, Rinn JL, Paquet AC, Chang HY, Young DM, et al. HOXA3 modulates injuryinduced mobilization and recruitment of bone marrow-derived cells. Stem Cells 2009; 27:1654-65; PMID:19544454; http://dx.doi.org/10.1002/ stem.90
    • (2009) Stem Cells , vol.27 , pp. 1654-1665
    • Mace, K.A.1    Restivo, T.E.2    Rinn, J.L.3    Paquet, A.C.4    Chang, H.Y.5    Young, D.M.6
  • 74
    • 78751693140 scopus 로고    scopus 로고
    • Hoxa3 promotes the differentiation of hematopoietic progenitor cells into proangiogenic Gr-1+CD11b+ myeloid cells
    • PMID:20974673
    • Mahdipour E, Charnock JC, Mace KA. Hoxa3 promotes the differentiation of hematopoietic progenitor cells into proangiogenic Gr-1+CD11b+ myeloid cells. Blood 2011; 117:815-26; PMID:20974673; http://dx.doi.org/10.1182/blood-2009-12- 259549
    • (2011) Blood , vol.117 , pp. 815-826
    • Mahdipour, E.1    Charnock, J.C.2    Mace, K.A.3
  • 75
    • 63849185760 scopus 로고    scopus 로고
    • Enhanced angiogenesis and reduced contraction in thrombospondin-2-null wounds is associated with increased levels of matrix metalloproteinases-2 and -9, and soluble VEGF
    • PMID:19029404
    • Maclauchlan S, Skokos EA, Agah A, Zeng J, Tian W, Davidson JM, et al. Enhanced angiogenesis and reduced contraction in thrombospondin-2-null wounds is associated with increased levels of matrix metalloproteinases-2 and -9, and soluble VEGF. J Histochem Cytochem 2009; 57:301-13; PMID:19029404; http://dx.doi.org/10.1369/jhc.2008.952689
    • (2009) J Histochem Cytochem , vol.57 , pp. 301-313
    • Maclauchlan, S.1    Skokos, E.A.2    Agah, A.3    Zeng, J.4    Tian, W.5    Davidson, J.M.6
  • 76
    • 0037590115 scopus 로고    scopus 로고
    • Hoxb13 knockout adult skin exhibits high levels of hyaluronan and enhanced wound healing
    • PMID:12759339
    • Mack JA, Abramson SR, Ben Y, Coffin JC, Rothrock JK, Maytin EV, et al. Hoxb13 knockout adult skin exhibits high levels of hyaluronan and enhanced wound healing. FASEB J 2003; 17:1352-4; PMID:12759339
    • (2003) FASEB J , vol.17 , pp. 1352-1354
    • Mack, J.A.1    Abramson, S.R.2    Ben, Y.3    Coffin, J.C.4    Rothrock, J.K.5    Maytin, E.V.6
  • 77
    • 76649111722 scopus 로고    scopus 로고
    • Persistent inflammation and angiogenesis during wound healing in K14-directed Hoxb13 transgenic mice
    • PMID:19759546
    • Mack JA, Maytin EV. Persistent inflammation and angiogenesis during wound healing in K14-directed Hoxb13 transgenic mice. J Invest Dermatol 2010; 130:856-65; PMID:19759546; http://dx.doi.org/10.1038/jid.2009.305
    • (2010) J Invest Dermatol , vol.130 , pp. 856-865
    • Mack, J.A.1    Maytin, E.V.2
  • 78
  • 79
    • 67649389706 scopus 로고    scopus 로고
    • Restoring transcription factor HoxA5 expression inhibits the growth of experimental hemangiomas in the brain
    • PMID:19458547
    • Zhu Y, Cuevas IC, Gabriel RA, Su H, Nishimura S, Gao P, et al. Restoring transcription factor HoxA5 expression inhibits the growth of experimental hemangiomas in the brain. J Neuropathol Exp Neurol 2009; 68:626-32; PMID:19458547; http://dx.doi.org/10.1097/NEN.0b013e3181a491ce
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 626-632
    • Zhu, Y.1    Cuevas, I.C.2    Gabriel, R.A.3    Su, H.4    Nishimura, S.5    Gao, P.6
  • 80
    • 0029740337 scopus 로고    scopus 로고
    • HOXB7 constitutively activates basic fibroblast growth factor in melanomas
    • PMID:8756643
    • Caré A, Silvani A, Meccia E, Mattia G, Stoppacciaro A, Parmiani G, et al. HOXB7 constitutively activates basic fibroblast growth factor in melanomas. Mol Cell Biol 1996; 16:4842-51; PMID:8756643
    • (1996) Mol Cell Biol , vol.16 , pp. 4842-4851
    • Caré, A.1    Silvani, A.2    Meccia, E.3    Mattia, G.4    Stoppacciaro, A.5    Parmiani, G.6
  • 81
    • 0032566065 scopus 로고    scopus 로고
    • Transduction of the SkBr3 breast carcinoma cell line with the HOXB7 gene induces bFGF expression, increases cell proliferation and reduces growth factor dependence
    • PMID:9681827
    • Caré A, Silvani A, Meccia E, Mattia G, Peschle C, Colombo MP. Transduction of the SkBr3 breast carcinoma cell line with the HOXB7 gene induces bFGF expression, increases cell proliferation and reduces growth factor dependence. Oncogene 1998; 16:3285-9; PMID:9681827; http://dx.doi.org/10.1038/ sj.onc.1201875
    • (1998) Oncogene , vol.16 , pp. 3285-3289
    • Caré, A.1    Silvani, A.2    Meccia, E.3    Mattia, G.4    Peschle, C.5    Colombo, M.P.6
  • 83
    • 0037143737 scopus 로고    scopus 로고
    • Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo
    • PMID:12163646
    • Lobov IB, Brooks PC, Lang RA. Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo. Proc Natl Acad Sci U S A 2002; 99:11205-10; PMID:12163646; http://dx.doi.org/10.1073/ pnas.172161899
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 11205-11210
    • Lobov, I.B.1    Brooks, P.C.2    Lang, R.A.3
  • 84
    • 75749132037 scopus 로고    scopus 로고
    • HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis
    • PMID:20080567
    • Hayashida T, Takahashi F, Chiba N, Brachtel E, Takahashi M, Godin-Heymann N, et al. HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis. Proc Natl Acad Sci U S A 2010; 107:1100-5; PMID:20080567; http://dx.doi.org/10.1073/pnas.0912710107
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 1100-1105
    • Hayashida, T.1    Takahashi, F.2    Chiba, N.3    Brachtel, E.4    Takahashi, M.5    Godin-Heymann, N.6
  • 86
    • 4944239035 scopus 로고    scopus 로고
    • An aminobisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis
    • PMID:15343380
    • Giraudo E, Inoue M, Hanahan D. An aminobisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis. J Clin Invest 2004; 114:623-33; PMID:15343380
    • (2004) J Clin Invest , vol.114 , pp. 623-633
    • Giraudo, E.1    Inoue, M.2    Hanahan, D.3
  • 87
    • 28644432204 scopus 로고    scopus 로고
    • VEGFR1-positive haematopoietic bone marrow progenitors initiate the premetastatic niche
    • PMID:16341007
    • Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the premetastatic niche. Nature 2005; 438:820-7; PMID:16341007; http://dx.doi.org/ 10.1038/nature04186
    • (2005) Nature , vol.438 , pp. 820-827
    • Kaplan, R.N.1    Riba, R.D.2    Zacharoulis, S.3    Bramley, A.H.4    Vincent, L.5    Costa, C.6
  • 88
    • 68749109536 scopus 로고    scopus 로고
    • A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth
    • PMID:19668347
    • Qian B, Deng Y, Im JH, Muschel RJ, Zou Y, Li J, et al. A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS One 2009; 4:e6562; PMID:19668347; http://dx.doi.org/10.1371/journal.pone.0006562
    • (2009) PLoS One , vol.4
    • Qian, B.1    Deng, Y.2    Im, J.H.3    Muschel, R.J.4    Zou, Y.5    Li, J.6
  • 89
    • 33751504690 scopus 로고    scopus 로고
    • Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
    • PMID:17128264
    • Hiratsuka S, Watanabe A, Aburatani H, Maru Y. Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat Cell Biol 2006; 8:1369-75; PMID:17128264; http://dx.doi.org/10.1038/ncb1507
    • (2006) Nat Cell Biol , vol.8 , pp. 1369-1375
    • Hiratsuka, S.1    Watanabe, A.2    Aburatani, H.3    Maru, Y.4
  • 90
    • 79960080321 scopus 로고    scopus 로고
    • Regulation of CCL2 expression by an upstream TALE homeodomain protein-binding site that synergizes with the site created by the A-2578G SNP
    • PMID:21760952
    • Page SH, Wright EK, Jr., Gama L, Clements JE. Regulation of CCL2 expression by an upstream TALE homeodomain protein-binding site that synergizes with the site created by the A-2578G SNP. PLoS One 2011; 6:e22052; PMID:21760952; http://dx.doi.org/10.1371/journal.pone.0022052
    • (2011) PLoS One , vol.6
    • Page, S.H.1    Wright Jr., E.K.2    Gama, L.3    Clements, J.E.4
  • 91
    • 34548644772 scopus 로고    scopus 로고
    • The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
    • PMID:17825402
    • De Santa F, Totaro MG, Prosperini E, Notarbartolo S, Testa G, Natoli G. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 2007; 130: 1083-94; PMID:17825402; http://dx.doi.org/10.1016/j.cell.2007.08.019
    • (2007) Cell , vol.130 , pp. 1083-1094
    • De Santa, F.1    Totaro, M.G.2    Prosperini, E.3    Notarbartolo, S.4    Testa, G.5    Natoli, G.6
  • 92
    • 35348849015 scopus 로고    scopus 로고
    • Hox genes in hematopoiesis and leukemogenesis
    • PMID:17934484
    • Argiropoulos B, Humphries RK. Hox genes in hematopoiesis and leukemogenesis. Oncogene 2007; 26:6766-76; PMID:17934484; http://dx.doi.org/10. 1038/sj.onc.1210760
    • (2007) Oncogene , vol.26 , pp. 6766-6776
    • Argiropoulos, B.1    Humphries, R.K.2
  • 93
    • 79959899727 scopus 로고    scopus 로고
    • Hox transcription factor regulation of adult bone-marrow-derived cell behaviour during tissue repair and regeneration
    • PMID:21513461
    • Mahdipour E, Mace KA. Hox transcription factor regulation of adult bone-marrow-derived cell behaviour during tissue repair and regeneration. Expert Opin Biol Ther 2011; 11:1079-90; PMID:21513461; http://dx.doi.org/10.1517/ 14712598.2011.579096
    • (2011) Expert Opin Biol Ther , vol.11 , pp. 1079-1090
    • Mahdipour, E.1    Mace, K.A.2
  • 94
    • 0032168459 scopus 로고    scopus 로고
    • MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis
    • PMID:9724755
    • Yu BD, Hanson RD, Hess JL, Horning SE, Korsmeyer SJ. MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. Proc Natl Acad Sci U S A 1998; 95: 10632-6; PMID:9724755; http://dx.doi.org/10.1073/pnas.95.18.10632
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 10632-10636
    • Yu, B.D.1    Hanson, R.D.2    Hess, J.L.3    Horning, S.E.4    Korsmeyer, S.J.5
  • 95
    • 23444445683 scopus 로고    scopus 로고
    • Epigenetic inheritance of chromatin states mediated by Polycomb and trithorax group proteins in Drosophila
    • PMID:15881890
    • Déjardin J, Cavalli G. Epigenetic inheritance of chromatin states mediated by Polycomb and trithorax group proteins in Drosophila. Prog Mol Subcell Biol 2005; 38:31-63; PMID:15881890; http://dx.doi.org/10.1007/3-540- 27310-7-2
    • (2005) Prog Mol Subcell Biol , vol.38 , pp. 31-63
    • Déjardin, J.1    Cavalli, G.2
  • 96
    • 33847084602 scopus 로고    scopus 로고
    • Genome regulation by polycomb and trithorax proteins
    • PMID:17320510
    • Schuettengruber B, Chourrout D, Vervoort M, Leblanc B, Cavalli G. Genome regulation by polycomb and trithorax proteins. Cell 2007; 128:735-45; PMID:17320510; http://dx.doi.org/10.1016/j.cell.2007.02.009
    • (2007) Cell , vol.128 , pp. 735-745
    • Schuettengruber, B.1    Chourrout, D.2    Vervoort, M.3    Leblanc, B.4    Cavalli, G.5
  • 97
    • 81855212627 scopus 로고    scopus 로고
    • Trithorax group proteins: Switching genes on and keeping them active
    • PMID:22108599
    • Schuettengruber B, Martinez AM, Iovino N, Cavalli G. Trithorax group proteins: switching genes on and keeping them active. Nat Rev Mol Cell Biol 2011; 12: 799-814; PMID:22108599; http://dx.doi.org/10.1038/nrm3230
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 799-814
    • Schuettengruber, B.1    Martinez, A.M.2    Iovino, N.3    Cavalli, G.4
  • 98
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • PMID:16630818
    • Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 2006; 125:301-13; PMID:16630818; http://dx.doi.org/10.1016/j.cell.2006.02. 043
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3    Guenther, M.G.4    Levine, S.S.5    Kumar, R.M.6
  • 99
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • PMID:16625203
    • Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 2006; 441:349-53; PMID:16625203; http://dx.doi.org/10.1038/ nature04733
    • (2006) Nature , vol.441 , pp. 349-353
    • Boyer, L.A.1    Plath, K.2    Zeitlinger, J.3    Brambrink, T.4    Medeiros, L.A.5    Lee, T.I.6
  • 100
    • 33846902276 scopus 로고    scopus 로고
    • The histone methyltransferase MLL is an upstream regulator of endothelial-cell sprout formation
    • PMID:17047146
    • Diehl F, Rössig L, Zeiher AM, Dimmeler S, Urbich C. The histone methyltransferase MLL is an upstream regulator of endothelial-cell sprout formation. Blood 2007; 109:1472-8; PMID:17047146; http://dx.doi.org/10.1182/ blood-2006-08-039651
    • (2007) Blood , vol.109 , pp. 1472-1478
    • Diehl, F.1    Rössig, L.2    Zeiher, A.M.3    Dimmeler, S.4    Urbich, C.5
  • 101
    • 77957277896 scopus 로고    scopus 로고
    • Mel-18, a mammalian Polycomb gene, regulates angiogenic gene expression of endothelial cells
    • PMID:20801102
    • Jung JH, Choi HJ, Maeng YS, Choi JY, Kim M, Kwon JY, et al. Mel-18, a mammalian Polycomb gene, regulates angiogenic gene expression of endothelial cells. Biochem Biophys Res Commun 2010; 400:523-30; PMID:20801102; http://dx.doi.org/10.1016/j.bbrc.2010.08.086
    • (2010) Biochem Biophys Res Commun , vol.400 , pp. 523-530
    • Jung, J.H.1    Choi, H.J.2    Maeng, Y.S.3    Choi, J.Y.4    Kim, M.5    Kwon, J.Y.6
  • 102
    • 80755140181 scopus 로고    scopus 로고
    • Loss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathway
    • PMID:21602890
    • Park JH, Lee JY, Shin DH, Jang KS, Kim HJ, Kong G. Loss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathway. Oncogene 2011; 30:4578-89; PMID:21602890; http://dx.doi.org/10.1038/onc.2011.174
    • (2011) Oncogene , vol.30 , pp. 4578-4589
    • Park, J.H.1    Lee, J.Y.2    Shin, D.H.3    Jang, K.S.4    Kim, H.J.5    Kong, G.6
  • 103
    • 68249128477 scopus 로고    scopus 로고
    • Epigenetic reprogramming during wound healing: Loss of polycomb-mediated silencing may enable upregulation of repair genes
    • PMID:19575012
    • Shaw T, Martin P. Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes. EMBO Rep 2009; 10:881-6; PMID:19575012; http://dx.doi.org/10.1038/embor.2009.102
    • (2009) EMBO Rep , vol.10 , pp. 881-886
    • Shaw, T.1    Martin, P.2
  • 104
    • 3042801308 scopus 로고    scopus 로고
    • SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
    • PMID:15225548
    • Cao R, Zhang Y. SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex. Mol Cell 2004; 15:57-67; PMID:15225548; http://dx.doi.org/10.1016/j.molcel.2004.06.020
    • (2004) Mol Cell , vol.15 , pp. 57-67
    • Cao, R.1    Zhang, Y.2
  • 105
    • 70350494322 scopus 로고    scopus 로고
    • Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells
    • PMID:19638619
    • Fiskus W, Wang Y, Sreekumar A, Buckley KM, Shi H, Jillella A, et al. Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells. Blood 2009; 114:2733-43; PMID:19638619; http://dx.doi.org/10. 1182/blood-2009-03-213496
    • (2009) Blood , vol.114 , pp. 2733-2743
    • Fiskus, W.1    Wang, Y.2    Sreekumar, A.3    Buckley, K.M.4    Shi, H.5    Jillella, A.6
  • 106
    • 33747732171 scopus 로고    scopus 로고
    • Tumor suppressor p16INK4A regulates polycomb-mediated DNA hypermethylation in human mammary epithelial cells
    • PMID:16766534
    • Reynolds PA, Sigaroudinia M, Zardo G, Wilson MB, Benton GM, Miller CJ, et al. Tumor suppressor p16INK4A regulates polycomb-mediated DNA hypermethylation in human mammary epithelial cells. J Biol Chem 2006; 281:24790-802; PMID:16766534; http://dx.doi.org/10.1074/jbc.M604175200
    • (2006) J Biol Chem , vol.281 , pp. 24790-24802
    • Reynolds, P.A.1    Sigaroudinia, M.2    Zardo, G.3    Wilson, M.B.4    Benton, G.M.5    Miller, C.J.6
  • 107
    • 77955983629 scopus 로고    scopus 로고
    • Noninvasive electromagnetic fields on keratinocyte growth and migration
    • PMID:19592020
    • Huo R, Ma Q, Wu JJ, Chin-Nuke K, Jing Y, Chen J, et al. Noninvasive electromagnetic fields on keratinocyte growth and migration. J Surg Res 2010; 162:299-307; PMID:19592020; http://dx.doi.org/10.1016/j.jss.2009.02.016
    • (2010) J Surg Res , vol.162 , pp. 299-307
    • Huo, R.1    Ma, Q.2    Wu, J.J.3    Chin-Nuke, K.4    Jing, Y.5    Chen, J.6
  • 109
    • 23844537411 scopus 로고    scopus 로고
    • Homeobox D10 induces phenotypic reversion of breast tumor cells in a three-dimensional culture model
    • PMID:16103068
    • Carrio M, Arderiu G, Myers C, Boudreau NJ. Homeobox D10 induces phenotypic reversion of breast tumor cells in a three-dimensional culture model. Cancer Res 2005; 65:7177-85; PMID:16103068; http://dx.doi.org/10.1158/0008- 5472.CAN-04-1717
    • (2005) Cancer Res , vol.65 , pp. 7177-7185
    • Carrio, M.1    Arderiu, G.2    Myers, C.3    Boudreau, N.J.4
  • 110
    • 35948942354 scopus 로고    scopus 로고
    • The prognostic biomarkers HOXB13, IL17BR, and CHDH are regulated by estrogen in breast cancer
    • PMID:17975144
    • Wang Z, Dahiya S, Provencher H, Muir B, Carney E, Coser K, et al. The prognostic biomarkers HOXB13, IL17BR, and CHDH are regulated by estrogen in breast cancer. Clin Cancer Res 2007; 13:6327-34; PMID:17975144; http://dx.doi.org/10.1158/1078-0432.CCR-07-0310
    • (2007) Clin Cancer Res , vol.13 , pp. 6327-6334
    • Wang, Z.1    Dahiya, S.2    Provencher, H.3    Muir, B.4    Carney, E.5    Coser, K.6
  • 111
    • 34248361968 scopus 로고    scopus 로고
    • Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarraybased methylated CpG island recovery assay
    • PMID:17369352
    • Rauch T, Wang Z, Zhang X, Zhong X, Wu X, Lau SK, et al. Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarraybased methylated CpG island recovery assay. Proc Natl Acad Sci U S A 2007; 104:5527-32; PMID:17369352; http://dx.doi.org/10.1073/pnas.0701059104
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 5527-5532
    • Rauch, T.1    Wang, Z.2    Zhang, X.3    Zhong, X.4    Wu, X.5    Lau, S.K.6
  • 112
    • 34249930780 scopus 로고    scopus 로고
    • Dysregulated expression of HOX and ParaHOX genes in human esophageal squamous cell carcinoma
    • PMID:17342311
    • Takahashi O, Hamada J, Abe M, Hata S, Asano T, Takahashi Y, et al. Dysregulated expression of HOX and ParaHOX genes in human esophageal squamous cell carcinoma. Oncol Rep 2007; 17:753-60; PMID:17342311
    • (2007) Oncol Rep , vol.17 , pp. 753-760
    • Takahashi, O.1    Hamada, J.2    Abe, M.3    Hata, S.4    Asano, T.5    Takahashi, Y.6
  • 113
    • 35548934558 scopus 로고    scopus 로고
    • MLL translocations, histone modifications and leukaemia stem-cell development
    • PMID:17957188
    • Krivtsov AV, Armstrong SA. MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer 2007; 7:823-33; PMID:17957188; http://dx.doi.org/10.1038/nrc2253
    • (2007) Nat Rev Cancer , vol.7 , pp. 823-833
    • Krivtsov, A.V.1    Armstrong, S.A.2
  • 114
    • 0038240453 scopus 로고    scopus 로고
    • Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: Dominance of HOX dysregulation
    • PMID:12637319
    • Ferrando AA, Armstrong SA, Neuberg DS, Sallan SE, Silverman LB, Korsmeyer SJ, et al. Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation. Blood 2003; 102:262-8; PMID:12637319; http://dx.doi.org/10.1182/blood-2002-10-3221
    • (2003) Blood , vol.102 , pp. 262-268
    • Ferrando, A.A.1    Armstrong, S.A.2    Neuberg, D.S.3    Sallan, S.E.4    Silverman, L.B.5    Korsmeyer, S.J.6
  • 115
    • 0142062911 scopus 로고    scopus 로고
    • MLL-rearranged leukemias: Insights from gene expression profiling
    • PMID:14582077
    • Armstrong SA, Golub TR, Korsmeyer SJ. MLL-rearranged leukemias: insights from gene expression profiling. Semin Hematol 2003; 40:268-73; PMID:14582077; http://dx.doi.org/10.1016/S0037-1963(03)00196-3
    • (2003) Semin Hematol , vol.40 , pp. 268-273
    • Armstrong, S.A.1    Golub, T.R.2    Korsmeyer, S.J.3
  • 116
    • 2342597203 scopus 로고    scopus 로고
    • HOXB13 homeodomain protein suppresses the growth of prostate cancer cells by the negative regulation of T-cell factor 4
    • PMID:15126340
    • Jung C, Kim RS, Lee SJ, Wang C, Jeng MH. HOXB13 homeodomain protein suppresses the growth of prostate cancer cells by the negative regulation of T-cell factor 4. Cancer Res 2004; 64: 3046-51; PMID:15126340; http://dx.doi.org/10.1158/0008-5472.CAN-03-2614
    • (2004) Cancer Res , vol.64 , pp. 3046-3051
    • Jung, C.1    Kim, R.S.2    Lee, S.J.3    Wang, C.4    Jeng, M.H.5
  • 117
    • 22044455309 scopus 로고    scopus 로고
    • HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation
    • PMID:15928669
    • Jung C, Kim RS, Zhang H, Lee SJ, Sheng H, Loehrer PJ, et al. HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation. Br J Cancer 2005; 92:2233-9; PMID:15928669; http://dx.doi.org/10.1038/sj.bjc.6602631
    • (2005) Br J Cancer , vol.92 , pp. 2233-2239
    • Jung, C.1    Kim, R.S.2    Zhang, H.3    Lee, S.J.4    Sheng, H.5    Loehrer, P.J.6
  • 118
    • 84863115448 scopus 로고    scopus 로고
    • The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway
    • PMID:21690342
    • Jin K, Kong X, Shah T, Penet MF, Wildes F, Sgroi DC, et al. The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway. Proc Natl Acad Sci U S A 2012; 109: 2736-41; PMID:21690342; http://dx.doi.org/10.1073/pnas.1018859108
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 2736-2741
    • Jin, K.1    Kong, X.2    Shah, T.3    Penet, M.F.4    Wildes, F.5    Sgroi, D.C.6
  • 119
    • 77951770118 scopus 로고    scopus 로고
    • HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype
    • PMID:20389018
    • Gilbert PM, Mouw JK, Unger MA, Lakins JN, Gbegnon MK, Clemmer VB, et al. HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. J Clin Invest 2010; 120:1535-50; PMID:20389018; http://dx.doi.org/10.1172/JCI39534
    • (2010) J Clin Invest , vol.120 , pp. 1535-1550
    • Gilbert, P.M.1    Mouw, J.K.2    Unger, M.A.3    Lakins, J.N.4    Gbegnon, M.K.5    Clemmer, V.B.6
  • 120
    • 0030942488 scopus 로고    scopus 로고
    • Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis
    • PMID:9058712
    • Lawrence HJ, Helgason CD, Sauvageau G, Fong S, Izon DJ, Humphries RK, et al. Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis. Blood 1997; 89:1922-30; PMID:9058712
    • (1997) Blood , vol.89 , pp. 1922-1930
    • Lawrence, H.J.1    Helgason, C.D.2    Sauvageau, G.3    Fong, S.4    Izon, D.J.5    Humphries, R.K.6
  • 121
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • PMID:10521349
    • Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999; 286:531-7; PMID:10521349; http://dx.doi.org/10.1126/science.286.5439.531
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1    Slonim, D.K.2    Tamayo, P.3    Huard, C.4    Gaasenbeek, M.5    Mesirov, J.P.6
  • 122
    • 0036782277 scopus 로고    scopus 로고
    • Deregulated homeobox gene expression in cancer: Cause or consequence?
    • PMID:12360280
    • Abate-Shen C. Deregulated homeobox gene expression in cancer: cause or consequence? Nat Rev Cancer 2002; 2:777-85; PMID:12360280; http://dx.doi.org/10. 1038/nrc907
    • (2002) Nat Rev Cancer , vol.2 , pp. 777-785
    • Abate-Shen, C.1
  • 124
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • PMID:17898713
    • Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007; 449:682-8; PMID:17898713; http://dx.doi.org/10.1038/nature06174
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 125
    • 77951605788 scopus 로고    scopus 로고
    • The Hox genes and their roles in oncogenesis
    • PMID:20357775
    • Shah N, Sukumar S. The Hox genes and their roles in oncogenesis. Nat Rev Cancer 2010; 10:361-71; PMID:20357775; http://dx.doi.org/10.1038/nrc2826
    • (2010) Nat Rev Cancer , vol.10 , pp. 361-371
    • Shah, N.1    Sukumar, S.2
  • 126
    • 0025359059 scopus 로고
    • The developmental effect of overexpressing a Ubx product in Drosophila embryos is dependent on its interactions with other homeotic products
    • PMID: 1970762
    • González-Reyes A, Morata G. The developmental effect of overexpressing a Ubx product in Drosophila embryos is dependent on its interactions with other homeotic products. Cell 1990; 61:515-22; PMID: 1970762; http://dx.doi.org/10.1016/0092-8674(90)90533-K
    • (1990) Cell , vol.61 , pp. 515-522
    • González-Reyes, A.1    Morata, G.2
  • 127
    • 0032431822 scopus 로고    scopus 로고
    • Functional dominance among Hox genes: Repression dominates activation in the regulation of Dpp
    • PMID:9811579
    • Capovilla M, Botas J. Functional dominance among Hox genes: repression dominates activation in the regulation of Dpp. Development 1998; 125:4949-57; PMID:9811579
    • (1998) Development , vol.125 , pp. 4949-4957
    • Capovilla, M.1    Botas, J.2
  • 128
    • 0025165214 scopus 로고
    • Are cross-regulatory interactions between homoeotic genes functionally significant?
    • PMID:1968232
    • González-Reyes A, Urquia N, Gehring WJ, Struhl G, Morata G. Are cross-regulatory interactions between homoeotic genes functionally significant? Nature 1990; 344:78-80; PMID:1968232; http://dx.doi.org/10.1038/344078a0
    • (1990) Nature , vol.344 , pp. 78-80
    • González-Reyes, A.1    Urquia, N.2    Gehring, W.J.3    Struhl, G.4    Morata, G.5
  • 129
    • 0026200238 scopus 로고
    • Patterning in the vertebrate limb
    • PMID:1688004
    • Duboule D. Patterning in the vertebrate limb. Curr Opin Genet Dev 1991; 1:211-6; PMID:1688004; http://dx.doi.org/10.1016/S0959-437X(05)80072-3
    • (1991) Curr Opin Genet Dev , vol.1 , pp. 211-216
    • Duboule, D.1
  • 130
    • 0342368849 scopus 로고    scopus 로고
    • Phenotypic suppression of empty spiracles is prevented by buttonhead
    • PMID:10830964
    • Schöck F, Reischl J, Wimmer E, Taubert H, Purnell BA, Jäckle H. Phenotypic suppression of empty spiracles is prevented by buttonhead. Nature 2000; 405:351-4; PMID:10830964; http://dx.doi.org/10.1038/35012620
    • (2000) Nature , vol.405 , pp. 351-354
    • Schöck, F.1    Reischl, J.2    Wimmer, E.3    Taubert, H.4    Purnell, B.A.5    Jäckle, H.6
  • 131
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-directed cleavage of HOXB8 mRNA
    • PMID:15105502
    • Yekta S, Shih IH, Bartel DP. MicroRNA-directed cleavage of HOXB8 mRNA. Science 2004; 304:594-6; PMID:15105502; http://dx.doi.org/10.1126/science. 1097434
    • (2004) Science , vol.304 , pp. 594-596
    • Yekta, S.1    Shih, I.H.2    Bartel, D.P.3
  • 132
    • 52149090746 scopus 로고    scopus 로고
    • MicroRNAs in the Hox network: An apparent link to posterior prevalence
    • PMID:18781158
    • Yekta S, Tabin CJ, Bartel DP. MicroRNAs in the Hox network: an apparent link to posterior prevalence. Nat Rev Genet 2008; 9:789-96; PMID:18781158; http://dx.doi.org/10.1038/nrg2400
    • (2008) Nat Rev Genet , vol.9 , pp. 789-796
    • Yekta, S.1    Tabin, C.J.2    Bartel, D.P.3
  • 133
    • 0028784065 scopus 로고
    • The Drosophila homeotic target gene centrosomin (cnn) encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for midgut morphogenesis
    • PMID:8582295
    • Heuer JG, Li K, Kaufman TC. The Drosophila homeotic target gene centrosomin (cnn) encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for midgut morphogenesis. Development 1995; 121:3861-76; PMID:8582295
    • (1995) Development , vol.121 , pp. 3861-3876
    • Heuer, J.G.1    Li, K.2    Kaufman, T.C.3
  • 134
    • 0027295299 scopus 로고
    • A homeotic gene cluster patterns the anteroposterior body axis of C. elegans
    • PMID:8101474
    • Wang BB, Müller-Immergluck MM, Austin J, Robinson NT, Chisholm A, Kenyon C. A homeotic gene cluster patterns the anteroposterior body axis of C. elegans. Cell 1993; 74:29-42; PMID:8101474; http://dx.doi.org/10.1016/0092- 8674(93)90292-X
    • (1993) Cell , vol.74 , pp. 29-42
    • Wang, B.B.1    Müller-Immergluck, M.M.2    Austin, J.3    Robinson, N.T.4    Chisholm, A.5    Kenyon, C.6
  • 135
    • 0027053874 scopus 로고
    • Ectopic expression of UBX and ABD-B proteins during Drosophila embryogenesis: Competition, not a functional hierarchy, explains phenotypic suppression
    • PMID:1363544
    • Lamka ML, Boulet AM, Sakonju S. Ectopic expression of UBX and ABD-B proteins during Drosophila embryogenesis: competition, not a functional hierarchy, explains phenotypic suppression. Development 1992; 116:841-54; PMID:1363544
    • (1992) Development , vol.116 , pp. 841-854
    • Lamka, M.L.1    Boulet, A.M.2    Sakonju, S.3
  • 136
    • 0037093507 scopus 로고    scopus 로고
    • Three habits of highly effective signaling pathways: Principles of transcriptional control by developmental cell signaling
    • PMID:12023297
    • Barolo S, Posakony JW. Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling. Genes Dev 2002; 16:1167-81; PMID:12023297; http://dx.doi.org/10.1101/gad.976502
    • (2002) Genes Dev , vol.16 , pp. 1167-1181
    • Barolo, S.1    Posakony, J.W.2
  • 137
    • 0028947525 scopus 로고
    • Pbx proteins display hexapep-tide-dependent cooperative DNA binding with a subset of Hox proteins
    • PMID:7729685
    • Chang CP, Shen WF, Rozenfeld S, Lawrence HJ, Largman C, Cleary ML. Pbx proteins display hexapep-tide-dependent cooperative DNA binding with a subset of Hox proteins. Genes Dev 1995; 9:663-74; PMID:7729685; http://dx.doi.org/10. 1101/gad.9.6.663
    • (1995) Genes Dev , vol.9 , pp. 663-674
    • Chang, C.P.1    Shen, W.F.2    Rozenfeld, S.3    Lawrence, H.J.4    Largman, C.5    Cleary, M.L.6
  • 138
    • 0029865897 scopus 로고    scopus 로고
    • Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA
    • PMID:8600458
    • Shen WF, Chang CP, Rozenfeld S, Sauvageau G, Humphries RK, Lu M, et al. Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA. Nucleic Acids Res 1996; 24:898-906; PMID:8600458; http://dx.doi.org/10.1093/ nar/24.5.898
    • (1996) Nucleic Acids Res , vol.24 , pp. 898-906
    • Shen, W.F.1    Chang, C.P.2    Rozenfeld, S.3    Sauvageau, G.4    Humphries, R.K.5    Lu, M.6
  • 140
    • 0031964860 scopus 로고    scopus 로고
    • Functional and regulatory interactions between Hox and extradenticle genes
    • PMID:9436985
    • Azpiazu N, Morata G. Functional and regulatory interactions between Hox and extradenticle genes. Genes Dev 1998; 12:261-73; PMID:9436985; http://dx.doi.org/10.1101/gad.12.2.261
    • (1998) Genes Dev , vol.12 , pp. 261-273
    • Azpiazu, N.1    Morata, G.2
  • 141
    • 0031007898 scopus 로고    scopus 로고
    • A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila
    • PMID:9171376
    • Jaffe L, Ryoo HD, Mann RS. A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila. Genes Dev 1997; 11:1327-40; PMID:9171376; http://dx.doi.org/10.1101/gad.11.10.1327
    • (1997) Genes Dev , vol.11 , pp. 1327-1340
    • Jaffe, L.1    Ryoo, H.D.2    Mann, R.S.3
  • 142
    • 0037148839 scopus 로고    scopus 로고
    • Hox protein mutation and macroevolution of the insect body plan
    • PMID: 11859370
    • Ronshaugen M, McGinnis N, McGinnis W. Hox protein mutation and macroevolution of the insect body plan. Nature 2002; 415:914-7; PMID: 11859370; http://dx.doi.org/10.1038/nature716
    • (2002) Nature , vol.415 , pp. 914-917
    • Ronshaugen, M.1    McGinnis, N.2    McGinnis, W.3
  • 143
    • 0347986652 scopus 로고    scopus 로고
    • HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8
    • PMID: 14701762
    • Chen H, Chung S, Sukumar S. HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8. Mol Cell Biol 2004; 24:924-35; PMID: 14701762; http://dx.doi.org/10.1128/MCB.24.2.924-935.2004
    • (2004) Mol Cell Biol , vol.24 , pp. 924-935
    • Chen, H.1    Chung, S.2    Sukumar, S.3
  • 144
    • 0031860728 scopus 로고    scopus 로고
    • Modulation of the human homeobox genes PRX-2 and HOXB13 in scarless fetal wounds
    • PMID:9665387
    • Stelnicki EJ, Arbeit J, Cass DL, Saner C, Harrison M, Largman C. Modulation of the human homeobox genes PRX-2 and HOXB13 in scarless fetal wounds. J Invest Dermatol 1998; 111:57-63; PMID:9665387; http://dx.doi.org/10. 1046/j.1523-1747.1998.00238.x
    • (1998) J Invest Dermatol , vol.111 , pp. 57-63
    • Stelnicki, E.J.1    Arbeit, J.2    Cass, D.L.3    Saner, C.4    Harrison, M.5    Largman, C.6
  • 145
    • 45049086810 scopus 로고    scopus 로고
    • Homeobox genes Hoxd3 and Hoxd8 are differentially expressed in fetal mouse excisional wounds
    • PMID:18570930
    • Jain K, Sykes V, Kordula T, Lanning D. Homeobox genes Hoxd3 and Hoxd8 are differentially expressed in fetal mouse excisional wounds. J Surg Res 2008; 148: 45-8; PMID:18570930; http://dx.doi.org/10.1016/j.jss.2008.02.053
    • (2008) J Surg Res , vol.148 , pp. 45-48
    • Jain, K.1    Sykes, V.2    Kordula, T.3    Lanning, D.4
  • 146
    • 0030810349 scopus 로고    scopus 로고
    • The human homeobox genes MSX-1, MSX-2, and MOX-1 are differentially expressed in the dermis and epidermis in fetal and adult skin
    • PMID:9373945
    • Stelnicki EJ, Kömüves LG, Holmes D, Clavin W, Harrison MR, Adzick NS, et al. The human homeobox genes MSX-1, MSX-2, and MOX-1 are differentially expressed in the dermis and epidermis in fetal and adult skin. Differentiation 1997; 62:33-41; PMID:9373945; http://dx.doi.org/10.1046/j.1432- 0436.1997.6210033.x
    • (1997) Differentiation , vol.62 , pp. 33-41
    • Stelnicki, E.J.1    Kömüves, L.G.2    Holmes, D.3    Clavin, W.4    Harrison, M.R.5    Adzick, N.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.