HOXB7 constitutively activates basic fibroblast growth factor in melanomas

Molecular and Cellular Biology

Volumn 16, Issue 9, 1996, Pages 4842-4851

  Carè, Alessandra ^a   Silvani, Anna ^b   Meccia, Ettore ^a   Mattia, Gianfranco ^a   Stoppacciaro, Antonella ^c   Parmiani, Giorgio ^b   Peschle, Cesare ^a,d   Colombo, Mario P ^b  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; HOMEODOMAIN PROTEIN;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; GENE CLUSTER; GENE EXPRESSION; HOMEOBOX; HUMAN; HUMAN CELL; MELANOCYTE; MELANOMA; MELANOMA CELL; PRIORITY JOURNAL; TRANSACTIVATION;

MAMMALIA;

EID: 0029740337     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.9.4842     Document Type: Article

References (55)

1. Adema, G. J., A. J. De Boer, R. van't Hullenaar, M. Denijn, D. J. Ruiter, A. M. Vogel, and C. G. Figdor. 1993. Melanocyte lineage-specific antigens recognized by monoclonal antibodies NKI-beteb, HMB-50, and HMB-45 are encoded by a single c-DNA. Am. J. Pathol. 143:1579-1585.
2. Anichini, A., R. Mortarini, G. Fossati, and G. Parmiani. 1986. Phenotype profile of clones from early cultures of human metastatic melanomas and its modulation by recombinant interferon γ. Int. J. Cancer 38:505-511.
3. Asselineau, D., B. A. Bernard, C. Bailly, and M. Darmon. 1989. Retinoic acid improves epidermal morphogenesis. Dev. Biol. 133:322-335.
4. Balling, R., G. Mutter, P. Gruss, and M. Kessll. 1989. Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox 1.1 in transgenic mice. Cell 58:337-347.
5. Beck, V., R. Oren, B. Amit, A. Levanon, M. Gorecki, and J. R. Hartman. 1987. Human Mn superoxide dismutase cDNA sequence. Nucleic Acids Res. 15:9076.
6. Becker, D., C. B. Meier, and M. Herlyn. 1989. Proliferation of human malignant melanomas is inhibited by antisense oligodeoxynucleotides targeted against basic fibroblast growth factor. EMBO J. 8:3685-3691.
7. Bieberich, C. J., F. H. Ruddle, and K. S. Stenn. 1992. Differential expression of the 3.1 gene in adult mouse skin. Ann. N. Y. Acad. Sci. 642:346-354.
8. Blatt, C., J. Lotem, and L. Sachs. 1992. Inhibition of specific pathways of myeloid cell differentiation by an activated Hox 2.4 homeobox gene. Cell Growth Differ. 6:671-676.
9. Bordoni, R., R. Fine, D. Murray, and A. Richmond. 1990. Characterization of the role of melanoma growth stimulatory activity (MGSA) in the growth of normal melanocytes, nevocytes, and malignant melanocytes. J. Cell. Biochem. 44:207-219.
10. Carè, A., G. Mattia, E. Montesoro, I. Parolini, G. Russo, M. P. Colombo, and C. Peschle. 1994. c-fes expression in ontogenetic development and hematopoietic differentiation. Oncogene 9:739-747.
11. Carè, A., U. Testa, A. Bassani, E. Tritarelli, E. Montesoro, P. Samoggia, L. Cianetti, and C. Peschle. 1994. Coordinate expression and proliferative role of HOXB genes in activated adult T lymphocytes. Mol. Cell. Biol. 14:4872-4877.
12. Cillo, C., P. Barba, G. Freschi, G. Bucciarelli, M. C. Magli, and E. Boncinelli. 1992. HOX gene expression in normal and neoplastic human kidney. Int. J. Cancer 51:892-897.
13. Colombo, M. P., C. Maccalli, S. Mattei, C. Melani, M. Radrizzani, and G. Parmiani. 1992. Expression of cytokine genes, including IL-6, in human melanoma cell lines. Melanoma Res. 2:181-189.
14. Condie, B. G., and M. R. Capecchi. 1994. Mice with targeted disruptions in the paralogous genes hoxa-3 and hod-3 reveal synergistic interaction. Nature (London) 370:304-307.
15. Dedera, D. A., E. K. Waller, D. P. LeBrun, A. Sen-Majumdar, M. E. Stevens, G. S. Barsh, and M. L. Cleary. 1993. Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice. Cell 74:833-838.
16. Deguchi, Y., and J. H. Kehre. 1993. High level expression of the homeobox gene HB24 in a human T-cell line confers the ability to form tumors in nude mice. Cancer Res. 53:373-377.
17. Deguchi, Y., J. F. Moroney, and J. H. Kehrl. 1991. Expression of the HOX-2.3 homeobox gene in human lymphocytes and lymphoid tissues. Blood 78:445-450.
18. Deschamps, J., and F. Meijlink. 1992. Mammalian homeobox genes in normal development and neoplasia. Crit. Res. Oncol. 3:117-173.
19. De Vita, G., P. Barba, N. Odartchenko, J.-C. Givel, G. Freschi, G. Bucciarelli, M. C. Magli, E. Boncinelli, and C. Cillo. 1993. Expression of homeobox containing genes in primary and metastatic colorectal cancer. Eur. J. Cancer 29A:887-893.
20. Edelmann, G. M., and F. S. Jones. 1993. Outside and downstream of the homeobox. J. Biol. Chem. 268:20683-20685.
21. Flamme, I., and W. Risau. 1992. Induction of vasculogenesis and hematopoiesis in vitro. Development 116:435-439.
22. Florkievitcz, R. Z., F. Shibata, T. Barankiewicz, A. Baird, A.-M. Gonzales, E. Florkiewicz, and N. Shah. 1991. Basic fibroblast growth factor gene expression. Ann. N. Y. Acad. Sci. 638:109-126.
23. Giampaolo, A., P. Sterpetti, D. Bulgarini, P. Samoggia, E. Pelosi, M. Valtieri, and C. Peschle. 1994. Key functional role and lineage-specific expression of selected HOXB genes in purified hematopoietic progenitor differentiation. Blood 84:3637-3647.
24. Giard, D. J., S. A. Aaorson, G. J. Todaro, P. Arnstein, J. H. Kersey, H. Dosik, and W. P. Parks. 1973. In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J. Natl. Cancer Inst. 51:1417-1423.
25. Goomer, R. S., B. D. Holst, I. C. Wood, F. S. Jones, and G. M. Edelmann. 1994. Regulation in vitro of an L-CAM enhancer by homeobox genes HOXD9 and HNF-1. Proc. Natl. Acad. Sci. USA 91:7985-7989.
26. Halaban, R., B. S. Kwon, S. Ghosh, P. Delli Bovi, and A. Baird. 1988. bFGF as an autocrine growth factor for human melanoma. Oncogene Res. 3:177-186.
27. Hatano, M., C. W. M. Roberts, M. Minden, W. N. Crist, and S. J. Korsmeyer. 1991. Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia. Science 253:79-82.
28. Herlyn, M., D. Guerry, and H. Koprowsky. 1985. Recombinant γ-interferon induced changes in expression and shedding of antigens associated with normal human melanocytes, nevus cells, and primary and metastatic melanoma cells. J. Immunol. 134:4226-4230.
29. Herlyn, M., J. Thurin, G. Balaban, J. L. Bennicelli, D. Herlyn, D. E. Elder, E. Bondi, G. DuPont, P. Nowell, W. H. Clark, and H. Koproski. 1985 Characteristics of cultured human melanocytes isolated from different stages of tumor progression. Cancer Res. 45:5670-5676.
30. Jones, F. S., G. Chalepakis, P. Gruss, and G. M. Edelmann. 1992. Activation of the cytotactin promoter by the homeobox-containing gene Evx-1. Proc. Natl. Acad. Sci. USA 89:2091-2095.
31. Jones, F. S., B. D. Holst, O. Minowa, E. M. De Robertis, and G. M. Edelmann. 1993. Binding and transcriptional activation of the promoter for the neural cell adhesion molecule by HOX C6 (HOX-3.3). Proc. Natl. Acad. Sci. USA 90:6557-6561.
32. Jones, F. S., E. A. Prediger, D. A. Bittner, E. M. De Robertis, and G. M. Edelmann. 1992. Cell adhesion molecules as targets for HOX genes: neural cell adhesion molecule promoter activity is modulated by cotransfection with HOX-2.5 and 2.4. Proc. Natl. Acad. Sci. USA 89:2086-2090.
33. Kalionis, B., and P. H. O'Farrell. 1993. Universal target sequence is bound in vitro by diverse homeodomains. Mech. Dcv. 43:57-70.
34. Kerbel, R. S. 1992. Expression of multi-cytokine resistance and multi-growth factor independence in advanced stage metastatic cancer. Am. J. Pathol. 141:519-524.
35. Kerbel, R. S., M. S. Man, and D. Dexter. 1984. A model of human cancer metastasis: extensive spontaneous and artificial metastasis of a human pigmented melanoma and derived variant sublines in nude mice. J. Natl. Cancer Inst. 72:93-101.
36. Kozlowsky, J. M., I. J. Fidler, D. Campbell, Z.-I. Xu, M. E. Kaighn, and I. R. Hart. 1984. Metastatic behaviour of human tumor cell lines grown in the nude mouse. Cancer Res. 44:3522-3529.
37. Krumlauf, R. 1994. HOX genes in vertebrate development. Cell 78:191-2111.
38. Lawrence, H. J., and C. Largman. 1992. Homeobox genes in normal hematopoiesis and leukemia. Blood 80:2445-2453.
39. Magli, M. C., P. Barba, A. Celetti, G. De Vita, C. Cillo, and E. Boncinelli. 1991. Coordinate regulation of HOX genes in human hematopoietic cells. Proc. Natl. Acad. Sci. USA 88:6348-6352.
40. Mattei, S., M. P. Colombo, C. Melani, A. Silvani, G. Parmiani, and M. Herlyn. 1994. Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes. Int. J. Cancer 56:853-857.
41. Matthews, C. H. E., K. Detmer, H. J. Lawrence, and C. Largman. 1993. Expression of the Hox 2.2 homeobox gene in murine embryonic epidermis. Differentialion 52:177-184.
42. Maulbecker, C. C., and P. Gruss. 1993. The oncogenic potential of deregulated homeobox genes. Cell Growth Differ. 4:431-441.
43. Mavilio, F. 1993. Regulation of homeo-box containing genes by morphogens. Eur. J. Biochem. 212:273-288.
44. McGregor, G. R., and C. T. Caskey. 1989. Construction of plasmids that express E. coli β-galactosidase in mammalian cells. Nucleic Acids Res. 17: 2365.
45. Perkins, A., K. Kongsuwan, J. Visvader, J. M. Adams, and S. Cory. 1990. Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia. Proc. Natl. Acad. Sci. USA 87:8398-8402.
46. Perkins, A. C., and S. Cory. 1993. Conditional immortalization of mouse myelomonocytic, megakaryocytic and mast cell progenitors by the Hox-2.4 homeobox gene. EMBO J. 12:3835-3846.
47. Petrini, M., M. T. Quaranta, U. Testa, P. Samoggia, E. Tritarelli, A. Carè, L. Cianetti, M. Valtieri, C. Barletta, and C. Peschle. 1992. Expression of selected human HOX-2 genes in B/T acute lymphoid leukemia and IL-2/IL-1β-stimulated natural killer lymphocytes. Blood 80:185-193.
48. Pollock, R. A., T. Sreenath, L. Ngo, and C. J. Bieberich. 1995. Gain of function mutations for paralogous Hox genes: implications for the evolution of Hox gene function. Proc. Natl. Acad. Sci. USA 92:4492-4496.
49. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
50. + subpopulations of human bone marrow cells. Proc. Natl. Acad. Sci. USA 91: 12223-12227.
51. Schadendorf, D., A. Moller, B. Algermissen, M. Worm, M. Sticherling, and B. M. Czarnetzki. 1993. IL-8 produced by human malignant melanoma cells in vitro is an essential autocrine growth factor. J. Immunol. 151:2667-2675.
52. Schweigerer, L., G. Neufeld, A. Mergia, J. A. Abraham, J. C. Fiddes, and D. Gospodarowicz. 1987. Basic fibroblast growth factor in human rhabdomyosarcoma cells: implication for the proliferation and neovascularization of myoblast-derived tumors. Proc. Natl. Acad. Sci. USA 84:842-846.
53. Scott, G. A., and L. A. Goldsmith. 1993. Homeobox genes and skin development: a review. J. Invest. Dermatol. 101:3-8.
54. Scott, M. P. 1992. Vertebrate homeobox gene nomenclature. Cell 71:551-553.
55. Simeone, A., F. Mavilio, D. Acampora, A. Giampaolo, A. Faiella, V. Zappavigna, M. D'Esposito, M. Pannese, G. Russo, E. Boncinelli, and C. Peschle. 1987. Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development. Proc. Natl. Acad. Sci. USA 84:4914-4918.