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Volumn 36, Issue 3, 2010, Pages 321-331

Heterogeneity of the tumor vasculature

Author keywords

Angiogenesis; Arterio venogenesis; Tumors; Vascular endothelial growth factor; VEGF A

Indexed keywords

ADENOVIRUS VECTOR; CATHEPSIN; CATHEPSIN B; CELL PROTEIN; CYSTEINE PROTEINASE INHIBITOR; FIBRIN; TRANSMEMBRANE 4 L SIX FAMILY 1 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN ANTIBODY; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR;

EID: 77953257462     PISSN: 00946176     EISSN: 10989064     Source Type: Journal    
DOI: 10.1055/s-0030-1253454     Document Type: Review
Times cited : (321)

References (60)
  • 1
    • 0033580889 scopus 로고    scopus 로고
    • Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
    • Holash J, Maisonpierre P C., Compton D et al. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 1999 284 (5422) 1994-1998
    • (1999) Science , vol.284 , Issue.5422 , pp. 1994-1998
    • Holash, J.1    Maisonpierre, P.C.2    Compton, D.3
  • 2
    • 0036033456 scopus 로고    scopus 로고
    • Vessel co-option: How tumors obtain blood supply in the absence of sprouting angiogenesis
    • Leenders W P., Küsters B, de Waal R M. Vessel co-option: how tumors obtain blood supply in the absence of sprouting angiogenesis. Endothelium 2002 9 (2) 83-87
    • (2002) Endothelium , vol.9 , Issue.2 , pp. 83-87
    • Leenders, W.P.1    Küsters, B.2    De Waal, R.M.3
  • 3
    • 39849102836 scopus 로고    scopus 로고
    • HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion
    • Du R, Lu K V., Petritsch C et al. HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell 2008 13 (3) 206-220
    • (2008) Cancer Cell , vol.13 , Issue.3 , pp. 206-220
    • Du, R.1    Lu, K.V.2    Petritsch, C.3
  • 4
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971 285 (21) 1182-1186
    • (1971) N Engl J Med , vol.285 , Issue.21 , pp. 1182-1186
    • Folkman, J.1
  • 6
    • 0033986761 scopus 로고    scopus 로고
    • Causes and consequences of tumour acidity and implications for treatment
    • Stubbs M, McSheehy P M., Griffiths J R., Bashford C L. Causes and consequences of tumour acidity and implications for treatment. Mol Med Today 2000 6 (1) 15-19
    • (2000) Mol Med Today , vol.6 , Issue.1 , pp. 15-19
    • Stubbs, M.1    McSheehy, P.M.2    Griffiths, J.R.3    Bashford, C.L.4
  • 7
    • 0034901463 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
    • Semenza G L. Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. Trends Mol Med 2001 7 (8) 345-350
    • (2001) Trends Mol Med , vol.7 , Issue.8 , pp. 345-350
    • Semenza, G.L.1
  • 8
    • 33746257413 scopus 로고    scopus 로고
    • Permeability properties of tumor surrogate blood vessels induced by VEGF-A
    • Nagy J A., Feng D, Vasile E et al. Permeability properties of tumor surrogate blood vessels induced by VEGF-A. Lab Invest 2006 86 (8) 767-780
    • (2006) Lab Invest , vol.86 , Issue.8 , pp. 767-780
    • Nagy, J.A.1    Feng, D.2    Vasile, E.3
  • 9
    • 49949152533 scopus 로고    scopus 로고
    • Tumor blood vessels In: Aird W Cambridge, United Kingdom Cambridge University Press
    • Dvorak H. Tumor blood vessels In: Aird W The Endothelium: A Comprehensive Reference. Cambridge, United Kingdom Cambridge University Press 2007
    • (2007) The Endothelium: A Comprehensive Reference
    • Dvorak, H.1
  • 10
    • 0037926778 scopus 로고    scopus 로고
    • Rous-Whipple Award Lecture. How tumors make bad blood vessels and stroma
    • Dvorak H F. Rous-Whipple Award Lecture. How tumors make bad blood vessels and stroma. Am J Pathol 2003 162 (6) 1747-1757
    • (2003) Am J Pathol , vol.162 , Issue.6 , pp. 1747-1757
    • Dvorak, H.F.1
  • 11
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak H F. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 1986 315 (26) 1650-1659
    • (1986) N Engl J Med , vol.315 , Issue.26 , pp. 1650-1659
    • Dvorak, H.F.1
  • 12
    • 19344363035 scopus 로고    scopus 로고
    • Gene expression signature of fibroblast serum response predicts human cancer progression: Similarities between tumors and wounds
    • Chang H Y., Sneddon J B., Alizadeh A A. et al. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol 2004 2 (2) E7
    • (2004) PLoS Biol , vol.2 , Issue.2
    • Chang, H.Y.1    Sneddon, J.B.2    Alizadeh, A.A.3
  • 13
    • 0028861231 scopus 로고
    • Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer
    • Brown L F., Berse B, Jackman R W. et al. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum Pathol 1995 26 (1) 86-91
    • (1995) Hum Pathol , vol.26 , Issue.1 , pp. 86-91
    • Brown, L.F.1    Berse, B.2    Jackman, R.W.3
  • 14
    • 0029155712 scopus 로고
    • Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia
    • Guidi A J., Abu-Jawdeh G, Berse B et al. Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia. J Natl Cancer Inst 1995 87 (16) 1237-1245
    • (1995) J Natl Cancer Inst , vol.87 , Issue.16 , pp. 1237-1245
    • Guidi, A.J.1    Abu-Jawdeh, G.2    Berse, B.3
  • 15
    • 33645989446 scopus 로고    scopus 로고
    • Overview of anti-VEGF therapy and angiogenesis. Part 1: Angiogenesis inhibition in solid tumor malignancies
    • Ellis L M., Rosen L, Gordon M S. Overview of anti-VEGF therapy and angiogenesis. Part 1: Angiogenesis inhibition in solid tumor malignancies. Clin Adv Hematol Oncol 2006 4 (suppl) 1-12
    • (2006) Clin Adv Hematol Oncol , vol.4 , Issue.SUPPL. , pp. 1-12
    • Ellis, L.M.1    Rosen, L.2    Gordon, M.S.3
  • 16
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004 350 (23) 2335-2342
    • (2004) N Engl J Med , vol.350 , Issue.23 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 17
    • 30944446883 scopus 로고    scopus 로고
    • Lessons from phase III clinical trials on anti-VEGF therapy for cancer
    • Jain R K., Duda D G., Clark J W., Loeffler J S. Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol 2006 3 (1) 24-40
    • (2006) Nat Clin Pract Oncol , vol.3 , Issue.1 , pp. 24-40
    • Jain, R.K.1    Duda, D.G.2    Clark, J.W.3    Loeffler, J.S.4
  • 18
    • 17344390961 scopus 로고    scopus 로고
    • Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor
    • Pettersson A, Nagy J A., Brown L F. et al. Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor. Lab Invest 2000 80 (1) 99-115
    • (2000) Lab Invest , vol.80 , Issue.1 , pp. 99-115
    • Pettersson, A.1    Nagy, J.A.2    Brown, L.F.3
  • 19
    • 33947414473 scopus 로고    scopus 로고
    • VEGF-A and the induction of pathological angiogenesis
    • Nagy J A., Dvorak H F., Dvorak A M. VEGF-A and the induction of pathological angiogenesis. Annu Rev Pathol 2007 2 251-275
    • (2007) Annu Rev Pathol , vol.2 , pp. 251-275
    • Nagy, J.A.1    Dvorak, H.F.2    Dvorak, A.M.3
  • 20
    • 0035106147 scopus 로고    scopus 로고
    • Glomeruloid microvascular proliferation follows adenoviral vascular permeability factor/vascular endothelial growth factor-164 gene delivery
    • Sundberg C, Nagy J A., Brown L F. et al. Glomeruloid microvascular proliferation follows adenoviral vascular permeability factor/vascular endothelial growth factor-164 gene delivery. Am J Pathol 2001 158 (3) 1145-1160
    • (2001) Am J Pathol , vol.158 , Issue.3 , pp. 1145-1160
    • Sundberg, C.1    Nagy, J.A.2    Brown, L.F.3
  • 21
    • 0037011070 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis
    • Nagy J A., Vasile E, Feng D et al. Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis. J Exp Med 2002 196 (11) 1497-1506
    • (2002) J Exp Med , vol.196 , Issue.11 , pp. 1497-1506
    • Nagy, J.A.1    Vasile, E.2    Feng, D.3
  • 22
    • 0037827662 scopus 로고    scopus 로고
    • VEGF-A induces angiogenesis, arteriogenesis, lymphangiogenesis, and vascular malformations
    • Nagy J A., Vasile E, Feng D et al. VEGF-A induces angiogenesis, arteriogenesis, lymphangiogenesis, and vascular malformations. Cold Spring Harb Symp Quant Biol 2002 67 227-237
    • (2002) Cold Spring Harb Symp Quant Biol , vol.67 , pp. 227-237
    • Nagy, J.A.1    Vasile, E.2    Feng, D.3
  • 23
    • 5044223787 scopus 로고    scopus 로고
    • Angiogenesis and lymphangiogenesis of skin cancers
    • Dadras S S., Detmar M. Angiogenesis and lymphangiogenesis of skin cancers. Hematol Oncol Clin North Am 2004 18 (5) 1059-1070, viii
    • (2004) Hematol Oncol Clin North Am , vol.18 , Issue.5 , pp. 1059-1070
    • Dadras, S.S.1    Detmar, M.2
  • 24
    • 1242269816 scopus 로고    scopus 로고
    • Role of lymphangiogenic factors in tumor metastasis
    • He Y, Karpanen T, Alitalo K. Role of lymphangiogenic factors in tumor metastasis. Biochim Biophys Acta 2004 1654 (1) 3-12
    • (2004) Biochim Biophys Acta , vol.1654 , Issue.1 , pp. 3-12
    • He, Y.1    Karpanen, T.2    Alitalo, K.3
  • 25
    • 0037698967 scopus 로고    scopus 로고
    • Angiogenesis and lymphangiogenesis in tumors: Insights from intravital microscopy
    • Jain R K. Angiogenesis and lymphangiogenesis in tumors: insights from intravital microscopy. Cold Spring Harb Symp Quant Biol 2002 67 239-248
    • (2002) Cold Spring Harb Symp Quant Biol , vol.67 , pp. 239-248
    • Jain, R.K.1
  • 26
    • 34250370123 scopus 로고    scopus 로고
    • Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting
    • Wirzenius M, Tammela T, Uutela M et al. Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting. J Exp Med 2007 204 (6) 1431-1440
    • (2007) J Exp Med , vol.204 , Issue.6 , pp. 1431-1440
    • Wirzenius, M.1    Tammela, T.2    Uutela, M.3
  • 27
    • 62549151252 scopus 로고    scopus 로고
    • Why are tumour blood vessels abnormal and why is it important to know?
    • Nagy J A., Chang S H., Dvorak A M., Dvorak H F. Why are tumour blood vessels abnormal and why is it important to know? Br J Cancer 2009 100 (6) 865-869
    • (2009) Br J Cancer , vol.100 , Issue.6 , pp. 865-869
    • Nagy, J.A.1    Chang, S.H.2    Dvorak, A.M.3    Dvorak, H.F.4
  • 28
    • 0025994605 scopus 로고
    • First steps of tumor-related angiogenesis
    • Paku S, Paweletz N. First steps of tumor-related angiogenesis. Lab Invest 1991 65 (3) 334-346
    • (1991) Lab Invest , vol.65 , Issue.3 , pp. 334-346
    • Paku, S.1    Paweletz, N.2
  • 29
    • 0026756163 scopus 로고
    • Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing
    • Brown L F., Yeo K T., Berse B et al. Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing. J Exp Med 1992 176 (5) 1375-1379
    • (1992) J Exp Med , vol.176 , Issue.5 , pp. 1375-1379
    • Brown, L.F.1    Yeo, K.T.2    Berse, B.3
  • 30
    • 0036143406 scopus 로고    scopus 로고
    • Morphological characteristics of the microvasculature in healing myocardial infarcts
    • Ren G, Michael L H., Entman M L., Frangogiannis N G. Morphological characteristics of the microvasculature in healing myocardial infarcts. J Histochem Cytochem 2002 50 (1) 71-79
    • (2002) J Histochem Cytochem , vol.50 , Issue.1 , pp. 71-79
    • Ren, G.1    Michael, L.H.2    Entman, M.L.3    Frangogiannis, N.G.4
  • 32
    • 0020449692 scopus 로고
    • Endothelial-cell proliferation in experimental tumours
    • Denekamp J, Hobson B. Endothelial-cell proliferation in experimental tumours. Br J Cancer 1982 46 (5) 711-720
    • (1982) Br J Cancer , vol.46 , Issue.5 , pp. 711-720
    • Denekamp, J.1    Hobson, B.2
  • 33
    • 0024615091 scopus 로고
    • Distensibility of single capillaries and venules in the rat and frog mesentery
    • Swayne G T., Smaje L H., Bergel D H. Distensibility of single capillaries and venules in the rat and frog mesentery. Int J Microcirc Clin Exp 1989 8 (1) 25-42
    • (1989) Int J Microcirc Clin Exp , vol.8 , Issue.1 , pp. 25-42
    • Swayne, G.T.1    Smaje, L.H.2    Bergel, D.H.3
  • 34
    • 66249098899 scopus 로고    scopus 로고
    • VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation
    • Chang S H., Kanasaki K, Gocheva V et al. VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Res 2009 69 (10) 4537-4544
    • (2009) Cancer Res , vol.69 , Issue.10 , pp. 4537-4544
    • Chang, S.H.1    Kanasaki, K.2    Gocheva, V.3
  • 35
    • 63849286557 scopus 로고    scopus 로고
    • Cystatins and cancer
    • Cox J L. Cystatins and cancer. Front Biosci 2009 14 463-474
    • (2009) Front Biosci , vol.14 , pp. 463-474
    • Cox, J.L.1
  • 36
    • 0030045180 scopus 로고    scopus 로고
    • The vesiculo-vacuolar organelle (VVO): A distinct endothelial cell structure that provides a transcellular pathway for macromolecular extravasation
    • Dvorak A M., Kohn S, Morgan E S., Fox P, Nagy J A., Dvorak H F. The vesiculo-vacuolar organelle (VVO): a distinct endothelial cell structure that provides a transcellular pathway for macromolecular extravasation. J Leukoc Biol 1996 59 (1) 100-115
    • (1996) J Leukoc Biol , vol.59 , Issue.1 , pp. 100-115
    • Dvorak, A.M.1    Kohn, S.2    Morgan, E.S.3    Fox, P.4    Nagy, J.A.5    Dvorak, H.F.6
  • 37
    • 0029890824 scopus 로고    scopus 로고
    • Vesiculo-vacuolar organelles and the regulation of venule permeability to macromolecules by vascular permeability factor, histamine, and serotonin
    • Feng D, Nagy J A., Hipp J, Dvorak H F., Dvorak A M. Vesiculo-vacuolar organelles and the regulation of venule permeability to macromolecules by vascular permeability factor, histamine, and serotonin. J Exp Med 1996 183 (5) 1981-1986
    • (1996) J Exp Med , vol.183 , Issue.5 , pp. 1981-1986
    • Feng, D.1    Nagy, J.A.2    Hipp, J.3    Dvorak, H.F.4    Dvorak, A.M.5
  • 38
    • 0030832884 scopus 로고    scopus 로고
    • Reinterpretation of endothelial cell gaps induced by vasoactive mediators in guinea-pig, mouse and rat: Many are transcellular pores
    • Feng D, Nagy J A., Hipp J, Pyne K, Dvorak H F., Dvorak A M. Reinterpretation of endothelial cell gaps induced by vasoactive mediators in guinea-pig, mouse and rat: many are transcellular pores. J Physiol 1997 504 (Pt 3) 747-761
    • (1997) J Physiol , vol.504 , Issue.PART 3 , pp. 747-761
    • Feng, D.1    Nagy, J.A.2    Hipp, J.3    Pyne, K.4    Dvorak, H.F.5    Dvorak, A.M.6
  • 39
    • 0033969993 scopus 로고    scopus 로고
    • Different pathways of macromolecule extravasation from hyperpermeable tumor vessels
    • Feng D, Nagy J A., Dvorak A M., Dvorak H F. Different pathways of macromolecule extravasation from hyperpermeable tumor vessels. Microvasc Res 2000 59 (1) 24-37
    • (2000) Microvasc Res , vol.59 , Issue.1 , pp. 24-37
    • Feng, D.1    Nagy, J.A.2    Dvorak, A.M.3    Dvorak, H.F.4
  • 40
    • 0028857418 scopus 로고
    • Pathogenesis of ascites tumor growth: Angiogenesis, vascular remodeling, and stroma formation in the peritoneal lining
    • Nagy J A., Morgan E S., Herzberg K T., Manseau E J., Dvorak A M., Dvorak H F. Pathogenesis of ascites tumor growth: angiogenesis, vascular remodeling, and stroma formation in the peritoneal lining. Cancer Res 1995 55 (2) 376-385
    • (1995) Cancer Res , vol.55 , Issue.2 , pp. 376-385
    • Nagy, J.A.1    Morgan, E.S.2    Herzberg, K.T.3    Manseau, E.J.4    Dvorak, A.M.5    Dvorak, H.F.6
  • 42
    • 0141921881 scopus 로고    scopus 로고
    • Glomeruloid microvascular proliferation is associated with p53 expression, germline BRCA1 mutations and an adverse outcome following breast cancer
    • Goffin J R., Straume O, Chappuis P O. et al. Glomeruloid microvascular proliferation is associated with p53 expression, germline BRCA1 mutations and an adverse outcome following breast cancer. Br J Cancer 2003 89 (6) 1031-1034
    • (2003) Br J Cancer , vol.89 , Issue.6 , pp. 1031-1034
    • Goffin, J.R.1    Straume, O.2    Chappuis, P.O.3
  • 43
    • 0036896003 scopus 로고    scopus 로고
    • Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers
    • Straume O, Chappuis P O., Salvesen H B. et al. Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers. Cancer Res 2002 62 (23) 6808-6811
    • (2002) Cancer Res , vol.62 , Issue.23 , pp. 6808-6811
    • Straume, O.1    Chappuis, P.O.2    Salvesen, H.B.3
  • 45
    • 0038692867 scopus 로고    scopus 로고
    • VEGF-A(164/165) and PlGF: Roles in angiogenesis and arteriogenesis
    • Nagy J A., Dvorak A M., Dvorak H F. VEGF-A(164/165) and PlGF: roles in angiogenesis and arteriogenesis. Trends Cardiovasc Med 2003 13 (5) 169-175
    • (2003) Trends Cardiovasc Med , vol.13 , Issue.5 , pp. 169-175
    • Nagy, J.A.1    Dvorak, A.M.2    Dvorak, H.F.3
  • 47
    • 0026233328 scopus 로고
    • Retinal capillary hemangioma
    • Baker J L. Retinal capillary hemangioma. J Am Optom Assoc 1991 62 (10) 776-779
    • (1991) J Am Optom Assoc , vol.62 , Issue.10 , pp. 776-779
    • Baker, J.L.1
  • 49
    • 0037238771 scopus 로고    scopus 로고
    • Retroorbital hemangiopericytoma and cavernous sinus schwannomacase report
    • Goel A, Muzumdar D, Desai K, Chagla A. Retroorbital hemangiopericytoma and cavernous sinus schwannomacase report. Neurol Med Chir (Tokyo) 2003 43 (1) 47-50
    • (2003) Neurol Med Chir (Tokyo) , vol.43 , Issue.1 , pp. 47-50
    • Goel, A.1    Muzumdar, D.2    Desai, K.3    Chagla, A.4
  • 50
    • 0033840389 scopus 로고    scopus 로고
    • Vasculogenic mimicry and tumor angiogenesis
    • Folberg R, Hendrix M J., Maniotis A J. Vasculogenic mimicry and tumor angiogenesis. Am J Pathol 2000 156 (2) 361-381
    • (2000) Am J Pathol , vol.156 , Issue.2 , pp. 361-381
    • Folberg, R.1    Hendrix, M.J.2    Maniotis, A.J.3
  • 51
    • 33644645280 scopus 로고    scopus 로고
    • VE-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway: Implications for vasculogenic mimicry
    • Hess A R., Seftor E A., Gruman L M., Kinch M S., Seftor R E., Hendrix M J. VE-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway: implications for vasculogenic mimicry. Cancer Biol Ther 2006 5 (2) 228-233
    • (2006) Cancer Biol Ther , vol.5 , Issue.2 , pp. 228-233
    • Hess, A.R.1    Seftor, E.A.2    Gruman, L.M.3    Kinch, M.S.4    Seftor, R.E.5    Hendrix, M.J.6
  • 52
    • 34247571036 scopus 로고    scopus 로고
    • Comparing vasculogenic mimicry with endothelial cell-lined vessels: Techniques for 3D reconstruction and quantitative analysis of tissue components from archival paraffin blocks
    • Lin A Y., Ai Z, Lee S C. et al. Comparing vasculogenic mimicry with endothelial cell-lined vessels: techniques for 3D reconstruction and quantitative analysis of tissue components from archival paraffin blocks. Appl Immunohistochem Mol Morphol 2007 15 (1) 113-119
    • (2007) Appl Immunohistochem Mol Morphol , vol.15 , Issue.1 , pp. 113-119
    • Lin, A.Y.1    Ai, Z.2    Lee, S.C.3
  • 53
    • 0033873782 scopus 로고    scopus 로고
    • Vasculogenic mimicry: How convincing, how novel, and how significant?
    • McDonald D M., Munn L, Jain R K. Vasculogenic mimicry: how convincing, how novel, and how significant? Am J Pathol 2000 156 (2) 383-388
    • (2000) Am J Pathol , vol.156 , Issue.2 , pp. 383-388
    • McDonald, D.M.1    Munn, L.2    Jain, R.K.3
  • 54
    • 0036985699 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: Therapeutic implications
    • Ferrara N. Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications. Semin Oncol 2002 29 (6, suppl 16) 10-14
    • (2002) Semin Oncol , vol.29 , Issue.6 SUPPL. 16 , pp. 10-14
    • Ferrara, N.1
  • 55
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • Kim K J., Li B, Winer J et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993 362 (6423) 841-844
    • (1993) Nature , vol.362 , Issue.6423 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3
  • 56
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain R K. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005 307 (5706) 58-62
    • (2005) Science , vol.307 , Issue.5706 , pp. 58-62
    • Jain, R.K.1
  • 57
    • 0038476608 scopus 로고    scopus 로고
    • Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
    • Bergers G, Song S, Meyer-Morse N, Bergsland E, Hanahan D. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest 2003 111 (9) 1287-1295
    • (2003) J Clin Invest , vol.111 , Issue.9 , pp. 1287-1295
    • Bergers, G.1    Song, S.2    Meyer-Morse, N.3    Bergsland, E.4    Hanahan, D.5
  • 58
    • 68149169793 scopus 로고    scopus 로고
    • Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase
    • Xue Q, Nagy J A., Manseau E J., Phung T L., Dvorak H F., Benjamin L E. Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase. Arterioscler Thromb Vasc Biol 2009 29 (8) 1172-1178
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , Issue.8 , pp. 1172-1178
    • Xue, Q.1    Nagy, J.A.2    Manseau, E.J.3    Phung, T.L.4    Dvorak, H.F.5    Benjamin, L.E.6
  • 60
    • 65949124896 scopus 로고    scopus 로고
    • The L6 protein TM4SF1 is critical for endothelial cell function and tumor angiogenesis
    • Shih S C., Zukauskas A, Li D et al. The L6 protein TM4SF1 is critical for endothelial cell function and tumor angiogenesis. Cancer Res 2009 69 (8) 3272-3277
    • (2009) Cancer Res , vol.69 , Issue.8 , pp. 3272-3277
    • Shih, S.C.1    Zukauskas, A.2    Li, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.