Modulation of the human homeobox genes PRX-2 and HOXB13 in scarless fetal wounds

Journal of Investigative Dermatology

Volumn 111, Issue 1, 1998, Pages 57-63

  Stelnicki, Eric J ^a,b   Arbeit, Jeff ^a   Cass, Darrell L ^c   Saner, Catherine ^d   Harrison, Michael ^a   Largman, Corey ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Homeodomain; Scar formation; Skin development; Wound healing

Indexed keywords

HOMEODOMAIN PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FETUS; FETUS DEVELOPMENT; HOMEOBOX; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCAR FORMATION; SKIN FIBROBLAST; SKIN INJURY; TISSUE REGENERATION; TRANSCRIPTION REGULATION; WOUND HEALING;

EID: 0031860728     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1998.00238.x     Document Type: Article

References (59)

1. Adzick NS, Lorenz HP: Cells, matrix, growth factors, and the surgeon. The biology of scarless fetal wound repair. Ann Surg 220:8-10, 1994
2. Andersen B, Weinberg WC, Rennekampff O, et al: Functions of the POU domain genes Skn-1a/i and Tst-1/Oct6/SCIP in epidermal differentiation. Genes Dev 11:1873-1884, 1997
3. Arbeit J, Olson D, Hanahan D: Upregulation of fibroblast growth factors and their receptors during multi-stage epidermal carcinogenesis in K14-HPV16 transgenic mice. Oncogene 13:1847-1857, 1996
4. Brockes JP: Amphibian limb regeneration: rebuilding a complex structure. Science 276:81-87, 1997
5. Brown R, Brockes JP: Identification and expression of a regeneration-specific homeobox gene in the newt limb blastema. Development 111:489-496, 1991
6. Burglin T: A comprehensive classification of homeobox genes. In: Duboule D (ed.). Guidebook to the Homeobox Genes. Oxford University Press, Oxford, 1994, pp. 25-71
7. Care A, Silvani A, Meccia E, et al: HOXB7 constitutively activates basic fibroblast growth factor in melanomas. Mol Cell Biol 16:4842-4851, 1996
8. Chisaka O, Capecchi MR: Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5. Nature 350:473-479, 1991
9. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159, 1987
10. Cotsarelis G, Sun T-T, Lavker RM: Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61:1329-1337, 1990
11. Crews L, Gates PB, Brown R, Joliot A, Foley C, Brockes JP, Gann AA: Expression and activity of the newt Msx-1 gene in relation to limb regeneration. Proc R Soc Lond B Biol Sci 259:161-171, 1995
12. Detmer K, Lawrence HJ, Largman C: Expression of class I homeobox genes in fetal and adult murine skin. J Invest Dermtol 101:517-522, 1993
13. Edelman GM, Jones FS: Cytotactin: a morphoregulatory molecule and a target for regulation by homeobox gene products. TIBS 17:228-232, 1992
14. Francis PH, Richardson MK, Brickell PM, Tickle C: Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb. Development 120:209-218, 1994
15. Gehring WJ, Affolter M, Burglin T: Homeodomain proteins. Ann Rev Biochem 63:487-526, 1994
16. Godwin AR, Capecchi MR: HoxC13 mutant mice lack external hair. Genes Dev 12:11-20, 1998
17. Goomer RS, Holst BD, Wood IC, Jones FS, Edelman GM: Regulation in vitro of an L-CAM enhancer by homeobox genes HOXD9 and HNF-1. Proc Natl Acad Sci USA 91:7985-7989, 1994
18. Gould AP, White RA: Connectin, a target of homeotic gene control in Drosophila. Develop 116:1163-1174, 1992
19. Gray JW, Kallioniemi A, Kallioniemi O, Pallavicini M, Waldman F, Pinkel D: Molecular cytogenetics: diagnosis and prognostic assessment. Curr Opin Biotechnol 3:623-631, 1992
20. He X, Treacy MN, Simmons DM, Ingraham HA, Swanson LW, Rosenfeld MG: Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature 340:35-42, 1989
21. Holleran WM, Takagi Y, Imokawa G, Jackson S, Lee JM, Elias PM: beta-Glucocerebrosidase activity in murine epidermis: characterization and localization in relation to differentiation. J Lipid Res 33:1201-1209, 1992
22. Hopkinson-Woolley J, Hughes D, Gordon S, Martin P: Macrophage recruitment during limb development and wound healing in the embryonic and foetal mouse. J Cell Sci 107:1159-1167, 1994
23. Immergluck K, Lawrence PA, Bienz M: Induction across germ layers in Drosophila mediated by a genetic cascade. Cell 62:261-268, 1990
24. Jabs EW, Muller U, Li X, et al: A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis. Cell 75:443-450, 1993
25. Jones FS, Prediger EA, De Bittner DA, RE, Edelman GM: Cell adhesion molecules as targets for Hox genes: neural cell adhesion molecule promoter activity is modulated by cotransfection with Hox-2.5 and -2.4. Proc Natl Acad Sci USA 89:2086-2090, 1992
26. Jones FS, Holst BD, Minowa O, DeRobertis EM, Edelman GM: Binding and transcriptional activation of the promoter for the neural cell adhesion molecule gene by HOXC6 (HOX-3.3). Proc Natl Acad Sci USA 90:6557-6561, 1993
27. Jones PH, Watt FM: Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell 73:713-724, 1993
28. de Jong R, Meijlink F: The homeobox gene S8: mesoderm-specific expression in presomite embryos and in cells cultured in vitro and modulation in differentiating pluripotent cells. Dev Biol 157:133-146, 1993
29. Joyner AL, Lebo RV, Kan YW, Tijan R, Cox DR, Martin GR: Comparative chromosome mapping of a conserved homoeo box region in mouse and human. Nature 314:173-175, 1985
30. Krumlauf R: Evolution of the vertebrate Hox homeobox genes. Bioessays 14:245-252, 1992
31. Lawrence HJ, Sauvageau G, Humphries RK, Largman C: The role of HOX genes in normal and leukemic hematopoiesis. Stem Cells 14:281-290, 1996
32. Leussink B, Brouwer A, El Khattabi M, Poelmann RE, Gittenberger-de Groot AC. Meijlink F: Expression patterns of the paired-related homeobox genes MHox Prx1 and S8/Prx2 suggest roles in development of the heart and forebrain. Mech Dev 52:51-64, 1995
33. Loh EY, Elliott JF, Cwirla S, Lanier LL, Davis M: Polymerase chain reaction with a single-sided specificity: Analysis of T cell receptor δ chain. Science 243:217-220, 1989
34. Longaker MT, Adzick NS: The biology of fetal wound healing: a review. Plast Reconstr Surg 87:788-798, 1991
35. Longaker MT, Moelleken BR, Cheng JC, et al: Fetal fracture healing in a lamb model. Plast Reconstr Surg 90:161-171, 1992
36. Lorenz HP, Adzick NS: Scarless skin wound repair in the fetus. West J Med 159:350-355, 1993
37. Lorenz HP, Longaker MT, Perkocha LA, Jennings RW, Harrison MR, Adzick NS: Scarless wound repair: a human fetal skin model. Development 114:253-259, 1992
38. Lorenz HP, Lin RY, Longaker MT, Whitby DJ, Adzick NS: The fetal fibroblast: the effector cell of scarless fetal skin repair. Plast Reconstr Surg 96:1251-1259;, 1995
39. Martin P: Wound healing - aiming for perfect skin regenertion. Science 276:75-81, 1997
40. Mathews CH, Detmer K, Lawrence HJ, Largman C: Expression of the Hox 2.2 homeobox gene in murine embryonic epidermis. Differentiation 52:177-184, 1993
41. Nath RK, Parks WC, Mackinnon SE, Hunter DA, Markham H, Weeks PM: The regulation of collagen in fetal skin wounds: mRNA localization and analysis. J Pediatr Surg 29:855-862, 1994
42. Opstelten DJ, Vogels R, Robert B, et al: The mouse homeobox gene, S8, is expressed during embryogenesis predominantly in mesenchyme. Mech Dev 34:29-41, 1991
43. Perkins A, Kongsuwan K, Visvader J, Adams JM, Cory S: Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia. Proc Natl Acad Sci USA 87:8398-8402, 1990
44. Rabin M, Hart C, Ferguson-Smith AP, McGinnis W, Levine M, Ruddle FH: Two homoeo box loci mapped in evolutionarily related mouse and human chromosomes. Nature 314:175-178, 1985
45. Reginelli AD, Wang YQ, Sassoon D, Muneoka K: Digit tip regeneration correlates with regions of Msx1 (Hox 7) expression in fetal and newborn mice. Development 121:1065-1076, 1995
46. Sauvageau G, Lansdorp PM, Eaves CE, et al: Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. Proc Natl Acad Sci USA 91:12223-12227, 1994
47. Sauvageau G, Thorsteinsdottir U, Eaves CJ, Lawrence HJ, Largman C, Lansdorp PM, Humphries RK: Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. Genes Dev 9:1753-1765, 1995
48. Sauvageau G, Thorsteinsdottir U, Hough MR, Hugo MR, Lawrence HJ, Largman C, Humphries RK: Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation. Immunity 6:13-22, 1997
49. Savard P, Tremblay M: Differential regulation of Hox C6 in the appendages of adult urodeles and anurans. J Mol Biol 249:879-889, 1995
50. Savard P, Gates PB, Brockes JP: Position dependent expression of a homeobox gene transcript in relation to amphibian limb regeneration. EMBO 7:4275-4282, 1988
51. Shen W-F, Montgomery JC, Rozenfeld S, Lawrence HJ, Buchberg A, Largman C: The Abd-B-like Hox proteins stabilize DNA binding by the Meisl homeodomain proteins. Mol Cell Biol 17:6448-6558, 1997
52. Stelnicki EJ, Komuves LG, Holmes D, Clavin W, Harrison MR, Adzick NS, Largman C: The human homeobox genes MSX-1, MSX-2, and MOX-1 are differentially expressed in the dermis and epidermis in fetal and adult skin. Differentiation 62:33-41, 1997
53. Stelnicki EJ, Komuves L, Kwong AO, et al: Differential HOX homeobox gene expression during human skin development. J Invest Dermatol 110:110-115, 1998
54. Taylor JJ, Heasman PA: Control genes for reverse transcriptase/polymerase chain reaction (RT-PCR). Br J Haematol 86:444-445, 1994
55. Thorsteinsdottir U, Sauvageau G, Hough MR, et al: Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia. Mol Cell Biol 17:495-505, 1997
56. Tomotsune D, Shoji H, Wakamatsu Y, Kondoh H, Takahashi N: A mouse homologue of the Drosophila tumour-suppressor gene I (2) gI controlled by Hox-C8 in vivo. Nature 365:69-72, 1993
57. Vieille-Grosjean I, Roullot V, Courtois G: Identification of homeobox-containing genes expressed in hematopoietic blast cells. Biochem Biophys Res Commun 185:785-792, 1992
58. Vogel A, Roberts-Clarke D, Niswander L: Effect of FGF on gene expression in chick limb bud cells in vivo and in vitro. Dev Biol 171:507-520, 1995
59. Zeltser L, Desplan C, Heintz N: Hoxb-13: a new Hox gene in a distant region of the HOXB cluster maintains colinearity. Development 122:2475-2484, 1996