Homeobox D1 regulates angiogenic functions of endothelial cells via integrin β1 expression

Biochemical and Biophysical Research Communications

Volumn 408, Issue 1, 2011, Pages 186-192

  Park, Hyojin ^a   Choi, Hyun Jung ^a   Kim, Jihye ^a   Kim, Minhyung ^b   Rho, Seung Sik ^a   Hwang, Daehee ^b   Kim, Young Myeong ^c   Kwon, Young Guen ^a  

^a Yonsei University   (South Korea)

^b Pohang University of Science and Technology (POSTECH)   (South Korea)

^c Kangwon National University   (South Korea)

Author keywords

Adhesion; Angiogenesis; Endothelial cell; Homeobox D1; Integrin 1; Migration

Indexed keywords

BETA1 INTEGRIN; HOMEODOMAIN PROTEIN;

ANGIOGENESIS; ARTICLE; BINDING SITE; CELL ADHESION; CELL FUNCTION; CELL MIGRATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOTHELIUM CELL; GENE; GENE SILENCING; HOMEOBOX D1 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIGENS, CD29; BINDING SITES; CELL ADHESION; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HOMEODOMAIN PROTEINS; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 79955381485     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.04.017     Document Type: Article

References (27)

1. Gorski D.H., Walsh K. Control of vascular cell differentiation by homeobox transcription factors. Trends in Cardiovascular Medicine 2003, 13:213-220.
2. Bandyopadhyay S., Ashraf M.Z., Daher P., Howe P.H., DiCorleto P.E. HOXA9 participates in the transcriptional activation of E-selectin in endothelial cells. Molecular and Cellular Biology 2007, 27:4207-4216.
3. Boudreau N.J., Varner J.A. The homeobox transcription factor HoxD3 promotes integrin α5β1 expression and function during angiogenesis. Journal of Biological Chemistry 2004, 279:4862-4868.
4. Cantile M., Schiavo G., Terracciano L., Cillo C. Homeobox genes in normal and abnormal vasculogenesis. Nutrition, Metabolism and Cardiovascular Diseases 2008, 18:651-658.
5. Kim S., Bell K., Mousa S.A., Varner J.A. Regulation of angiogenesis in vivo by ligation of integrin α5β1 with the central cell-binding domain of fibronectin. American Journal of Pathology 2000, 156:1345-1362.
6. D.G. Stupack, D.A. Cheresh, ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands, Science's STKE [Electronic Resource]: Signal Transduction Knowledge Environment 2002 (2002).
7. Eliceiri B.P., Cheresh D.A. Role of αv integrins during angiogenesis. Cancer Journal 2000, 6:S245-S249.
8. Senger D.R., Claffey K.P., Benes J.E., Perruzzi C.A., Sergiou A.P., Detmar M. Angiogenesis promoted by vascular endothelial growth factor: regulation through α1β1 and α2β1 integrins. Proceedings of the National Academy of Sciences of the United States of America 1997, 94:13612-13617.
9. Maeng Y.S., Choi H.J., Kwon J.Y., Park Y.W., Choi K.S., Min J.K., Kim Y.H., Suh P.G., Kang K.S., Won M.H., Kim Y.M., Kwon Y.G. Endothelial progenitor cell homing: prominent role of the IGF2-IGF2R-PLC22 axis. Blood 2009, 113:233-243.
10. Marin V., Kaplanski G., Grès S., Farnarier C., Bongrand P. Endothelial cell culture: protocol to obtain and cultivate human umbilical endothelial cells. Journal of Immunological Methods 2001, 254:183-190.
11. Min J.K., Cho Y.L., Choi J.H., Kim Y., Jeong H.K., Young S.Y., Rho J., Mochizuki N., Kim Y.M., Goo T.O., Kwon Y.G. Receptor activator of nuclear factor (NF)-κB ligand (RANKL) increases vascular permeability: impaired permeability and angiogenesis in eNOS-deficient mice. Blood 2007, 109:1495-1502.
12. Bloch W., Forsberg E., Lentini S., Brakebusch C., Martin K., Krell H.W., Weidle U.H., Addicks K., Fässler R. Integrin is essential for teratoma growth and angiogenesis. Journal of Cell Biology 1997, 139:265-278.
13. Haider S., Ballester B., Smedley D., Zhang J., Rice P., Kasprzyk A. BioMart central portal - unified access to biological data. Nucleic Acids Research 2009, 37:W23-W27.
14. Thijs G., Moreau Y., De Smet F., Mathys J., Lescot M., Rombauts S., Rouze P., De Moor B., Marchal K. INCLUSive: INtegrated clustering, upstream sequence retrieval and motif sampling. Bioinformatics 2002, 18:331-332.
15. Newburger D.E., Bulyk M.L. UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. Nucleic Acids Research 2009, 37:D77-D82.
16. Zappavigna V., Falciola L., Citterich M.H., Mavilio F., Bianchi M.E. HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation. EMBO Journal 1996, 15:4981-4991.
17. Gorski D.H., Walsh K. The role of homeobox genes in vascular remodeling and angiogenesis. Circulation Research 2000, 87:865-872.
18. + cells of hypertensive patients. Journal of Hypertension 2007, 25:2093-2099.
19. Belotti D., Clausse N., Flagiello D., Alami Y., Daukandt M., Deroanne C., Malfoy B., Boncinelli E., Faiella A., Castronovo V. Expression and modulation of homeobox genes from cluster B in endothelial cells. Laboratory Investigation 1998, 78:1291-1299.
20. Myers C., Charboneau A., Boudreau N. Homeobox B3 promotes capillary morphogenesis and angiogenesis. Journal of Cell Biology 2000, 148:343-351.
21. Astrof S., Hynes R.O. Fibronectins in vascular morphogenesis. Angiogenesis 2009, 12:165-175.
22. Silva R., D'Amico G., Hodivala-Dilke K.M., Reynolds L.E. Integrins: the keys to unlocking angiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology 2008, 28:1703-1713.
23. Hynes R.O. Cell-matrix adhesion in vascular development. Journal of Thrombosis and Haemostasis 2007, 5:32-40.
24. Carlson T.R., Hu H., Braren R., Kim Y.H., Wang R.A. Cell-autonomous requirement for β1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice. Development 2008, 135:2193-2202.
25. Francis S.E., Goh K.L., Hodivala-Dilke K., Bader B.L., Stark M., Davidson D., Hynes R.O. Central roles of α5β1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arteriosclerosis, Thrombosis, and Vascular Biology 2002, 22:927-933.
26. Fassler R., Meyer M. Consequences of lack of β1 integrin gene expression in mice. Genes and Development 1995, 9:1896-1908.
27. Fässler R., Pfaff M., Murphy J., Noegel A.A., Johansson S., Timpl R., Albrecht R. Lack of β1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts. Journal of Cell Biology 1995, 128:979-988.