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Volumn 6, Issue 12, 2011, Pages

Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 CIP1/WAF1 and p16 INK4a in vascular endothelial cells

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MEOX1; TRANSCRIPTION FACTOR MEOX2; UNCLASSIFIED DRUG; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DNA; HOMEODOMAIN PROTEIN; MEOX1 PROTEIN, MOUSE; MEOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SP1;

EID: 83755228645     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029099     Document Type: Article
Times cited : (50)

References (59)
  • 1
    • 38549161152 scopus 로고    scopus 로고
    • Cell fate determination during G1 phase progression
    • Blomen VA, Boonstra J, (2007) Cell fate determination during G1 phase progression. Cell Mol Life Sci 64: 3084-3104.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 3084-3104
    • Blomen, V.A.1    Boonstra, J.2
  • 2
    • 33644913165 scopus 로고    scopus 로고
    • The role of therapeutic angiogenesis in tissue repair and regeneration
    • quiz 501-492
    • Li WW, Talcott KE, Zhai AW, Kruger EA, Li VW, (2005) The role of therapeutic angiogenesis in tissue repair and regeneration. Adv Skin Wound Care 18: 491-500; quiz 501-492.
    • (2005) Adv Skin Wound Care , vol.18 , pp. 491-500
    • Li, W.W.1    Talcott, K.E.2    Zhai, A.W.3    Kruger, E.A.4    Li, V.W.5
  • 3
    • 0035345030 scopus 로고    scopus 로고
    • Regulation of angiogenesis in the endometrium
    • Smith SK, (2001) Regulation of angiogenesis in the endometrium. Trends Endocrinol Metab 12: 147-151.
    • (2001) Trends Endocrinol Metab , vol.12 , pp. 147-151
    • Smith, S.K.1
  • 4
    • 28744456297 scopus 로고    scopus 로고
    • Angiogenesis during exercise and training
    • Bloor CM, (2005) Angiogenesis during exercise and training. Angiogenesis 8: 263-271.
    • (2005) Angiogenesis , vol.8 , pp. 263-271
    • Bloor, C.M.1
  • 6
    • 0347416785 scopus 로고    scopus 로고
    • Molecular mechanisms of replicative senescence in endothelial cells
    • Foreman KE, Tang J, (2003) Molecular mechanisms of replicative senescence in endothelial cells. Exp Gerontol 38: 1251-1257.
    • (2003) Exp Gerontol , vol.38 , pp. 1251-1257
    • Foreman, K.E.1    Tang, J.2
  • 7
    • 24644497236 scopus 로고    scopus 로고
    • Cellular senescence in vivo: its relevance in ageing and cardiovascular disease
    • Erusalimsky JD, Kurz DJ, (2005) Cellular senescence in vivo: its relevance in ageing and cardiovascular disease. Exp Gerontol 40: 634-642.
    • (2005) Exp Gerontol , vol.40 , pp. 634-642
    • Erusalimsky, J.D.1    Kurz, D.J.2
  • 8
    • 0035130153 scopus 로고    scopus 로고
    • Differential expression of thymosin beta-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: evidence for senescent endothelial cells in vivo at sites of atherosclerosis
    • Vasile E, Tomita Y, Brown LF, Kocher O, Dvorak HF, (2001) Differential expression of thymosin beta-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: evidence for senescent endothelial cells in vivo at sites of atherosclerosis. Faseb J 15: 458-466.
    • (2001) Faseb J , vol.15 , pp. 458-466
    • Vasile, E.1    Tomita, Y.2    Brown, L.F.3    Kocher, O.4    Dvorak, H.F.5
  • 9
    • 0037007075 scopus 로고    scopus 로고
    • Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction
    • Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, et al. (2002) Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Circulation 105: 1541-1544.
    • (2002) Circulation , vol.105 , pp. 1541-1544
    • Minamino, T.1    Miyauchi, H.2    Yoshida, T.3    Ishida, Y.4    Yoshida, H.5
  • 10
    • 0242361641 scopus 로고    scopus 로고
    • Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis
    • Minamino T, Yoshida T, Tateno K, Miyauchi H, Zou Y, et al. (2003) Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis. Circulation 108: 2264-2269.
    • (2003) Circulation , vol.108 , pp. 2264-2269
    • Minamino, T.1    Yoshida, T.2    Tateno, K.3    Miyauchi, H.4    Zou, Y.5
  • 11
    • 0027296739 scopus 로고
    • Reduction of nitric oxide producing activity associated with in vitro aging in cultured human umbilical vein endothelial cell
    • Sato I, Morita I, Kaji K, Ikeda M, Nagao M, et al. (1993) Reduction of nitric oxide producing activity associated with in vitro aging in cultured human umbilical vein endothelial cell. Biochem Biophys Res Commun 195: 1070-1076.
    • (1993) Biochem Biophys Res Commun , vol.195 , pp. 1070-1076
    • Sato, I.1    Morita, I.2    Kaji, K.3    Ikeda, M.4    Nagao, M.5
  • 12
    • 0035851216 scopus 로고    scopus 로고
    • Aging enhances the sensitivity of endothelial cells toward apoptotic stimuli: important role of nitric oxide
    • Hoffmann J, Haendeler J, Aicher A, Rossig L, Vasa M, et al. (2001) Aging enhances the sensitivity of endothelial cells toward apoptotic stimuli: important role of nitric oxide. Circ Res 89: 709-715.
    • (2001) Circ Res , vol.89 , pp. 709-715
    • Hoffmann, J.1    Haendeler, J.2    Aicher, A.3    Rossig, L.4    Vasa, M.5
  • 13
    • 0035955754 scopus 로고    scopus 로고
    • eNOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization
    • Matsushita H, Chang E, Glassford AJ, Cooke JP, Chiu CP, et al. (2001) eNOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization. Circ Res 89: 793-798.
    • (2001) Circ Res , vol.89 , pp. 793-798
    • Matsushita, H.1    Chang, E.2    Glassford, A.J.3    Cooke, J.P.4    Chiu, C.P.5
  • 14
    • 0033711708 scopus 로고    scopus 로고
    • Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle
    • Ekholm SV, Reed SI, (2000) Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle. Curr Opin Cell Biol 12: 676-684.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 676-684
    • Ekholm, S.V.1    Reed, S.I.2
  • 15
    • 33846967463 scopus 로고    scopus 로고
    • The homeobox gene GAX activates p21WAF1/CIP1 expression in vascular endothelial cells through direct interaction with upstream AT-rich sequences
    • Chen Y, Leal AD, Patel S, Gorski DH, (2007) The homeobox gene GAX activates p21WAF1/CIP1 expression in vascular endothelial cells through direct interaction with upstream AT-rich sequences. J Biol Chem 282: 507-517.
    • (2007) J Biol Chem , vol.282 , pp. 507-517
    • Chen, Y.1    Leal, A.D.2    Patel, S.3    Gorski, D.H.4
  • 16
    • 64549140317 scopus 로고    scopus 로고
    • A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a
    • Irelan JT, Gutierrez Del Arroyo A, Gutierrez A, Peters G, Quon KC, et al. (2009) A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a. PLoS One 4: e5067.
    • (2009) PLoS One , vol.4
    • Irelan, J.T.1    Gutierrez Del Arroyo, A.2    Gutierrez, A.3    Peters, G.4    Quon, K.C.5
  • 17
    • 78650472007 scopus 로고    scopus 로고
    • C/EBPbeta controls exercise-induced cardiac growth and protects against pathological cardiac remodeling
    • Bostrom P, Mann N, Wu J, Quintero PA, Plovie ER, et al. (2010) C/EBPbeta controls exercise-induced cardiac growth and protects against pathological cardiac remodeling. Cell 143: 1072-1083.
    • (2010) Cell , vol.143 , pp. 1072-1083
    • Bostrom, P.1    Mann, N.2    Wu, J.3    Quintero, P.A.4    Plovie, E.R.5
  • 18
    • 0030946646 scopus 로고    scopus 로고
    • Embryonic expression of the Gax homeodomain protein in cardiac, smooth, and skeletal muscle
    • Skopicki HA, Lyons GE, Schatteman G, Smith RC, Andres V, et al. (1997) Embryonic expression of the Gax homeodomain protein in cardiac, smooth, and skeletal muscle. Circ Res 80: 452-462.
    • (1997) Circ Res , vol.80 , pp. 452-462
    • Skopicki, H.A.1    Lyons, G.E.2    Schatteman, G.3    Smith, R.C.4    Andres, V.5
  • 19
    • 0030681252 scopus 로고    scopus 로고
    • Forced expression of the homeodomain protein Gax inhibits cardiomyocyte proliferation and perturbs heart morphogenesis
    • Fisher SA, Siwik E, Branellec D, Walsh K, Watanabe M, (1997) Forced expression of the homeodomain protein Gax inhibits cardiomyocyte proliferation and perturbs heart morphogenesis. Development 124: 4405-4413.
    • (1997) Development , vol.124 , pp. 4405-4413
    • Fisher, S.A.1    Siwik, E.2    Branellec, D.3    Walsh, K.4    Watanabe, M.5
  • 20
    • 28844478432 scopus 로고    scopus 로고
    • Meox1Cre: a mouse line expressing Cre recombinase in somitic mesoderm
    • Jukkola T, Trokovic R, Maj P, Lamberg A, Mankoo B, et al. (2005) Meox1Cre: a mouse line expressing Cre recombinase in somitic mesoderm. Genesis 43: 148-153.
    • (2005) Genesis , vol.43 , pp. 148-153
    • Jukkola, T.1    Trokovic, R.2    Maj, P.3    Lamberg, A.4    Mankoo, B.5
  • 21
    • 49949107971 scopus 로고    scopus 로고
    • Developmental origin of smooth muscle cells in the descending aorta in mice
    • Wasteson P, Johansson BR, Jukkola T, Breuer S, Akyurek LM, et al. (2008) Developmental origin of smooth muscle cells in the descending aorta in mice. Development 135: 1823-1832.
    • (2008) Development , vol.135 , pp. 1823-1832
    • Wasteson, P.1    Johansson, B.R.2    Jukkola, T.3    Breuer, S.4    Akyurek, L.M.5
  • 22
    • 24744457932 scopus 로고    scopus 로고
    • Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
    • Wu Z, Guo H, Chow N, Sallstrom J, Bell RD, et al. (2005) Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease. Nat Med 11: 959-965.
    • (2005) Nat Med , vol.11 , pp. 959-965
    • Wu, Z.1    Guo, H.2    Chow, N.3    Sallstrom, J.4    Bell, R.D.5
  • 23
    • 34249689634 scopus 로고    scopus 로고
    • Blood and lymphatic endothelial cell-specific differentiation programs are stringently controlled by the tissue environment
    • Amatschek S, Kriehuber E, Bauer W, Reininger B, Meraner P, et al. (2007) Blood and lymphatic endothelial cell-specific differentiation programs are stringently controlled by the tissue environment. Blood 109: 4777-4785.
    • (2007) Blood , vol.109 , pp. 4777-4785
    • Amatschek, S.1    Kriehuber, E.2    Bauer, W.3    Reininger, B.4    Meraner, P.5
  • 24
    • 20444408381 scopus 로고    scopus 로고
    • Hedgehog signaling induces cardiomyogenesis in P19 cells
    • Gianakopoulos PJ, Skerjanc IS, (2005) Hedgehog signaling induces cardiomyogenesis in P19 cells. J Biol Chem 280: 21022-21028.
    • (2005) J Biol Chem , vol.280 , pp. 21022-21028
    • Gianakopoulos, P.J.1    Skerjanc, I.S.2
  • 25
    • 0030610836 scopus 로고    scopus 로고
    • p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene
    • Smith RC, Branellec D, Gorski DH, Guo K, Perlman H, et al. (1997) p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene. Genes Dev 11: 1674-1689.
    • (1997) Genes Dev , vol.11 , pp. 1674-1689
    • Smith, R.C.1    Branellec, D.2    Gorski, D.H.3    Guo, K.4    Perlman, H.5
  • 26
    • 0037709253 scopus 로고    scopus 로고
    • Inhibition of endothelial cell activation by the homeobox gene Gax
    • Gorski DH, Leal AJ, (2003) Inhibition of endothelial cell activation by the homeobox gene Gax. J Surg Res 111: 91-99.
    • (2003) J Surg Res , vol.111 , pp. 91-99
    • Gorski, D.H.1    Leal, A.J.2
  • 27
    • 0027256035 scopus 로고
    • Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells
    • Gorski DH, LePage DF, Patel CV, Copeland NG, Jenkins NA, et al. (1993) Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells. Mol Cell Biol 13: 3722-3733.
    • (1993) Mol Cell Biol , vol.13 , pp. 3722-3733
    • Gorski, D.H.1    LePage, D.F.2    Patel, C.V.3    Copeland, N.G.4    Jenkins, N.A.5
  • 28
    • 0028929751 scopus 로고
    • Expression of gax, a growth arrest homeobox gene, is rapidly down-regulated in the rat carotid artery during the proliferative response to balloon injury
    • Weir L, Chen D, Pastore C, Isner JM, Walsh K, (1995) Expression of gax, a growth arrest homeobox gene, is rapidly down-regulated in the rat carotid artery during the proliferative response to balloon injury. J Biol Chem 270: 5457-5461.
    • (1995) J Biol Chem , vol.270 , pp. 5457-5461
    • Weir, L.1    Chen, D.2    Pastore, C.3    Isner, J.M.4    Walsh, K.5
  • 29
    • 33744792301 scopus 로고    scopus 로고
    • Down-regulation of the gax gene in smooth muscle cells of the splenic vein of portal hypertension patients
    • Zeng JH, Yang Z, Xu J, Qiu ML, Lin KC, (2006) Down-regulation of the gax gene in smooth muscle cells of the splenic vein of portal hypertension patients. Hepatobiliary Pancreat Dis Int 5: 242-245.
    • (2006) Hepatobiliary Pancreat Dis Int , vol.5 , pp. 242-245
    • Zeng, J.H.1    Yang, Z.2    Xu, J.3    Qiu, M.L.4    Lin, K.C.5
  • 30
    • 0142010691 scopus 로고    scopus 로고
    • The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites
    • Mankoo BS, Skuntz S, Harrigan I, Grigorieva E, Candia A, et al. (2003) The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites. Development 130: 4655-4664.
    • (2003) Development , vol.130 , pp. 4655-4664
    • Mankoo, B.S.1    Skuntz, S.2    Harrigan, I.3    Grigorieva, E.4    Candia, A.5
  • 31
    • 1642403669 scopus 로고    scopus 로고
    • Meox homeodomain proteins are required for Bapx1 expression in the sclerotome and activate its transcription by direct binding to its promoter
    • Rodrigo I, Bovolenta P, Mankoo BS, Imai K, (2004) Meox homeodomain proteins are required for Bapx1 expression in the sclerotome and activate its transcription by direct binding to its promoter. Mol Cell Biol 24: 2757-2766.
    • (2004) Mol Cell Biol , vol.24 , pp. 2757-2766
    • Rodrigo, I.1    Bovolenta, P.2    Mankoo, B.S.3    Imai, K.4
  • 32
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR, (1989) Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77: 51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 34
    • 0028829465 scopus 로고
    • Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter
    • Datto MB, Yu Y, Wang XF, (1995) Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter. J Biol Chem 270: 28623-28628.
    • (1995) J Biol Chem , vol.270 , pp. 28623-28628
    • Datto, M.B.1    Yu, Y.2    Wang, X.F.3
  • 35
    • 8544264635 scopus 로고    scopus 로고
    • Interplay between HIV-1 Vpr and Sp1 modulates p21(WAF1) gene expression in human astrocytes
    • Amini S, Saunders M, Kelley K, Khalili K, Sawaya BE, (2004) Interplay between HIV-1 Vpr and Sp1 modulates p21(WAF1) gene expression in human astrocytes. J Biol Chem 279: 46046-46056.
    • (2004) J Biol Chem , vol.279 , pp. 46046-46056
    • Amini, S.1    Saunders, M.2    Kelley, K.3    Khalili, K.4    Sawaya, B.E.5
  • 36
    • 0029000724 scopus 로고
    • Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression
    • Udvadia AJ, Templeton DJ, Horowitz JM, (1995) Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression. Proc Natl Acad Sci U S A 92: 3953-3957.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3953-3957
    • Udvadia, A.J.1    Templeton, D.J.2    Horowitz, J.M.3
  • 37
    • 11244325724 scopus 로고    scopus 로고
    • Inhibition of p53-mediated transcriptional responses by mithramycin A
    • Koutsodontis G, Kardassis D, (2004) Inhibition of p53-mediated transcriptional responses by mithramycin A. Oncogene 23: 9190-9200.
    • (2004) Oncogene , vol.23 , pp. 9190-9200
    • Koutsodontis, G.1    Kardassis, D.2
  • 38
    • 77952536463 scopus 로고    scopus 로고
    • Estrogen regulated expression of the p21 Waf1/Cip1 gene in estrogen receptor positive human breast cancer cells
    • Mandal S, Davie JR, (2010) Estrogen regulated expression of the p21 Waf1/Cip1 gene in estrogen receptor positive human breast cancer cells. J Cell Physiol 224: 28-32.
    • (2010) J Cell Physiol , vol.224 , pp. 28-32
    • Mandal, S.1    Davie, J.R.2
  • 39
    • 0029047362 scopus 로고
    • A biomarker that identifies senescent human cells in culture and in aging skin in vivo
    • Dimri GP, Lee X, Basile G, Acosta M, Scott G, et al. (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A 92: 9363-9367.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.2    Basile, G.3    Acosta, M.4    Scott, G.5
  • 40
    • 0030657868 scopus 로고    scopus 로고
    • Siamois is required for formation of Spemann's organizer
    • Kessler DS, (1997) Siamois is required for formation of Spemann's organizer. Proc Natl Acad Sci U S A 94: 13017-13022.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13017-13022
    • Kessler, D.S.1
  • 41
    • 34547124864 scopus 로고    scopus 로고
    • Dlx homeobox genes promote cortical interneuron migration from the basal forebrain by direct repression of the semaphorin receptor neuropilin-2
    • Le TN, Du G, Fonseca M, Zhou QP, Wigle JT, et al. (2007) Dlx homeobox genes promote cortical interneuron migration from the basal forebrain by direct repression of the semaphorin receptor neuropilin-2. J Biol Chem 282: 19071-19081.
    • (2007) J Biol Chem , vol.282 , pp. 19071-19081
    • Le, T.N.1    Du, G.2    Fonseca, M.3    Zhou, Q.P.4    Wigle, J.T.5
  • 43
    • 2442688110 scopus 로고    scopus 로고
    • Intracellular localization of homopolymeric amino acid-containing proteins expressed in mammalian cells
    • Oma Y, Kino Y, Sasagawa N, Ishiura S, (2004) Intracellular localization of homopolymeric amino acid-containing proteins expressed in mammalian cells. J Biol Chem 279: 21217-21222.
    • (2004) J Biol Chem , vol.279 , pp. 21217-21222
    • Oma, Y.1    Kino, Y.2    Sasagawa, N.3    Ishiura, S.4
  • 44
    • 62149119245 scopus 로고    scopus 로고
    • Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment
    • Salichs E, Ledda A, Mularoni L, Alba MM, de la Luna S, (2009) Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment. PLoS Genet 5: e1000397.
    • (2009) PLoS Genet , vol.5
    • Salichs, E.1    Ledda, A.2    Mularoni, L.3    Alba, M.M.4    de la Luna, S.5
  • 45
    • 33847272589 scopus 로고    scopus 로고
    • Enhanced autophagic cell death in expanded polyhistidine variants of HOXA1 reduces PBX1-coupled transcriptional activity and inhibits neuronal differentiation
    • Paraguison RC, Higaki K, Yamamoto K, Matsumoto H, Sasaki T, et al. (2007) Enhanced autophagic cell death in expanded polyhistidine variants of HOXA1 reduces PBX1-coupled transcriptional activity and inhibits neuronal differentiation. J Neurosci Res 85: 479-487.
    • (2007) J Neurosci Res , vol.85 , pp. 479-487
    • Paraguison, R.C.1    Higaki, K.2    Yamamoto, K.3    Matsumoto, H.4    Sasaki, T.5
  • 46
    • 79953320011 scopus 로고    scopus 로고
    • VentX trans-activates p53 and p16ink4a to regulate cellular senescence
    • Wu X, Gao H, Ke W, Hager M, Xiao S, et al. (2011) VentX trans-activates p53 and p16ink4a to regulate cellular senescence. J Biol Chem 286: 12693-12701.
    • (2011) J Biol Chem , vol.286 , pp. 12693-12701
    • Wu, X.1    Gao, H.2    Ke, W.3    Hager, M.4    Xiao, S.5
  • 47
    • 30044432705 scopus 로고    scopus 로고
    • Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells
    • Simmons SO, Horowitz JM, (2006) Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells. Biochem J 393: 397-409.
    • (2006) Biochem J , vol.393 , pp. 397-409
    • Simmons, S.O.1    Horowitz, J.M.2
  • 48
    • 0035933539 scopus 로고    scopus 로고
    • Homeodomain proteins Mox1 and Mox2 associate with Pax1 and Pax3 transcription factors
    • Stamataki D, Kastrinaki M, Mankoo BS, Pachnis V, Karagogeos D, (2001) Homeodomain proteins Mox1 and Mox2 associate with Pax1 and Pax3 transcription factors. FEBS Lett 499: 274-278.
    • (2001) FEBS Lett , vol.499 , pp. 274-278
    • Stamataki, D.1    Kastrinaki, M.2    Mankoo, B.S.3    Pachnis, V.4    Karagogeos, D.5
  • 49
    • 0033080402 scopus 로고    scopus 로고
    • Transcriptional regulation of the p21((WAF1/CIP1)) gene
    • Gartel AL, Tyner AL, (1999) Transcriptional regulation of the p21((WAF1/CIP1)) gene. Exp Cell Res 246: 280-289.
    • (1999) Exp Cell Res , vol.246 , pp. 280-289
    • Gartel, A.L.1    Tyner, A.L.2
  • 50
    • 0032832571 scopus 로고    scopus 로고
    • c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1
    • Kardassis D, Papakosta P, Pardali K, Moustakas A, (1999) c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1. J Biol Chem 274: 29572-29581.
    • (1999) J Biol Chem , vol.274 , pp. 29572-29581
    • Kardassis, D.1    Papakosta, P.2    Pardali, K.3    Moustakas, A.4
  • 51
    • 0033523778 scopus 로고    scopus 로고
    • Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites
    • Kivinen L, Tsubari M, Haapajarvi T, Datto MB, Wang XF, et al. (1999) Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites. Oncogene 18: 6252-6261.
    • (1999) Oncogene , vol.18 , pp. 6252-6261
    • Kivinen, L.1    Tsubari, M.2    Haapajarvi, T.3    Datto, M.B.4    Wang, X.F.5
  • 52
    • 0034464787 scopus 로고    scopus 로고
    • Androgen induction of cyclin-dependent kinase inhibitor p21 gene: role of androgen receptor and transcription factor Sp1 complex
    • Lu S, Jenster G, Epner DE, (2000) Androgen induction of cyclin-dependent kinase inhibitor p21 gene: role of androgen receptor and transcription factor Sp1 complex. Mol Endocrinol 14: 753-760.
    • (2000) Mol Endocrinol , vol.14 , pp. 753-760
    • Lu, S.1    Jenster, G.2    Epner, D.E.3
  • 53
    • 0035836706 scopus 로고    scopus 로고
    • Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3
    • Gartel AL, Ye X, Goufman E, Shianov P, Hay N, et al. (2001) Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3. Proc Natl Acad Sci U S A 98: 4510-4515.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4510-4515
    • Gartel, A.L.1    Ye, X.2    Goufman, E.3    Shianov, P.4    Hay, N.5
  • 54
    • 0035800746 scopus 로고    scopus 로고
    • Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein
    • Koutsodontis G, Tentes I, Papakosta P, Moustakas A, Kardassis D, (2001) Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein. J Biol Chem 276: 29116-29125.
    • (2001) J Biol Chem , vol.276 , pp. 29116-29125
    • Koutsodontis, G.1    Tentes, I.2    Papakosta, P.3    Moustakas, A.4    Kardassis, D.5
  • 55
    • 0035859818 scopus 로고    scopus 로고
    • Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21(WAF1/CIP1) expression in keratinocyte differentiation
    • Santini MP, Talora C, Seki T, Bolgan L, Dotto GP, (2001) Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21(WAF1/CIP1) expression in keratinocyte differentiation. Proc Natl Acad Sci U S A 98: 9575-9580.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 9575-9580
    • Santini, M.P.1    Talora, C.2    Seki, T.3    Bolgan, L.4    Dotto, G.P.5
  • 56
    • 0037159245 scopus 로고    scopus 로고
    • The role of Sp1 family members, the proximal GC-rich motifs, and the upstream enhancer region in the regulation of the human cell cycle inhibitor p21WAF-1/Cip1 gene promoter
    • Koutsodontis G, Moustakas A, Kardassis D, (2002) The role of Sp1 family members, the proximal GC-rich motifs, and the upstream enhancer region in the regulation of the human cell cycle inhibitor p21WAF-1/Cip1 gene promoter. Biochemistry 41: 12771-12784.
    • (2002) Biochemistry , vol.41 , pp. 12771-12784
    • Koutsodontis, G.1    Moustakas, A.2    Kardassis, D.3
  • 57
    • 3843126775 scopus 로고    scopus 로고
    • A LIM protein, Hic-5, functions as a potential coactivator for Sp1
    • Shibanuma M, Kim-Kaneyama JR, Sato S, Nose K, (2004) A LIM protein, Hic-5, functions as a potential coactivator for Sp1. J Cell Biochem 91: 633-645.
    • (2004) J Cell Biochem , vol.91 , pp. 633-645
    • Shibanuma, M.1    Kim-Kaneyama, J.R.2    Sato, S.3    Nose, K.4
  • 58
    • 38049077461 scopus 로고    scopus 로고
    • Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter
    • Hwang-Verslues WW, Sladek FM, (2008) Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter. Mol Endocrinol 22: 78-90.
    • (2008) Mol Endocrinol , vol.22 , pp. 78-90
    • Hwang-Verslues, W.W.1    Sladek, F.M.2
  • 59
    • 8344274464 scopus 로고    scopus 로고
    • Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis
    • Csoka AB, English SB, Simkevich CP, Ginzinger DG, Butte AJ, et al. (2004) Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis. Aging Cell 3: 235-243.
    • (2004) Aging Cell , vol.3 , pp. 235-243
    • Csoka, A.B.1    English, S.B.2    Simkevich, C.P.3    Ginzinger, D.G.4    Butte, A.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.