Homeobox B3 promotes capillary morphogenesis and angiogenesis

Journal of Cell Biology

Volumn 148, Issue 2, 2000, Pages 343-351

  Myers, Connie ^a   Charboneau, Aubri ^b   Boudreau, Nancy ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endothelial cells; Ephrin; Extracellular matrix; Hox; Neovascularization

Indexed keywords

EPHRIN; INTEGRIN; UROKINASE;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CAPILLARY; CAPILLARY ENDOTHELIUM; CELL ADHESION; CELL INVASION; CELL MIGRATION; CHICKEN; CONTROLLED STUDY; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; HOMEOBOX; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTISENSE ELEMENTS (GENETICS); CAPILLARIES; CELLS, CULTURED; DERMIS; ENDOTHELIUM, VASCULAR; EPHRIN-A1; EPHRIN-B1; GENES, HOMEOBOX; HUMANS; MEMBRANE PROTEINS; MORPHOGENESIS; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEINS; QUAIL; RECEPTOR PROTEIN-TYROSINE KINASES; RECOMBINANT FUSION PROTEINS;

EID: 0034707595     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.148.2.343     Document Type: Article

References (37)

1. Adams, R.M., G.A. Wilkinson, C. Weiss, F. Diella, N.W. Gale, U. Deutsch, W. Risau, and R. Kloin. 1999. Rules of ephrin B1 and EphB receptors in cardiovascular development: demarcation of arterial venous domains. vascular morphogenesis and sprouting angiogenesis. Genes. Dev. 18:2165-2173.
2. Ades, W., F.J. Candal, R.A. Swerlick, V.G. George, S. Summers., D.C. Bosse, and T.J. Lawley. 1992. HMEC-1-establishment of an immortalized human microvascular ondothelial cell line. J. Invest. Dermatol. 99:683-690.
3. Bader, B.L., H. Rayburn, D. Crowley, and R.O. Hynes, 1998. Extensive vasculogenesis, angiogenesis and organogenesis precede lethality in mice lacking all αv integrins. Cell. 95:507-520.
4. Belotti, D., N. Clausse, D. Flagiello, Y. Alami, M. Daukandt, C. Deroanne, B. Malfoy, E. Boncinelli, A. Faiella, and V. Castronovo, 1998. Expression and modulation of homenbox genes from cluster B in endothelial cells, Lab. Invest. 78:1291-1299.
5. Botas, J. 1993. Control of morphogenesis and differentiation hy Hom/Hox genes. Curr. Opin. Cell Biol. 5:1015-1022.
6. Boudreau, N., and M.J. Bissell. 1998. Extracellular matrix signaling: integration of form and function in normal and malignant cells. Curr. Opin Cell Biol. 10:640-646.
7. Boudreau, N., C. Andrews, A. Srebrow, A. Ravanpay, and D.A Cheresh. 1997. Hox D3 induces an angiogenic phenotype in endothelial cells. J. Cell Biol. 139:257-264.
8. Bouillet, P., M. Oulad-Abdelghani, S. Vicaire, J.-M. Gamier, B. Schuhaur, P. Dolle, and P. Chambon. 1995. Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gone Stral (mouse Lerk2). Dev. Biol. 170:420-433.
9. Brooks, P.C., A.M.P. Montgomery, M. Rosonfeld, R.A. Riesfeld, T. Hu, G. Klier, and D.A. Cheresh, 1994. Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell. 79:1157-1164.
10. Chon, F., and M.R. Capecchi. 1999. Paralogous mouse Hox genes, Hoxa9, Hoxb9, Hoxd9, function together to control development of the mammary gland in response to pregnancy. Proc. Natl. Acad. Sci. USA. 96:541-546.
11. Chen, J., and H.E. Ruley. 1998. An enhancer element in the EphA2 (Eck) gene sufficient for rhombomere-specific expression is activated by Hox A1 and Hox B1 homeobox proteins. J. Biol. Chem. 273:24670-24675.
12. Cillo, C., A. Faiella, M. Cantile, and B. Boncinelli. 1999. Homeobox genes and cancer. Exp. Cell Res. 248:1-9.
13. Condie, B.G., and M.R. Capecchi. 1994. Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions. Nature. 370:304-307.
14. Daniel, T.O., E. Stein, D.P. Cerretti, P.L. St. John, B. Robert, and D.R. Abrahamson. 1996. ELK and LERK-2 in developing kidney and microvascular endothelial assembly. Kidney Int. Suppl. 57:S73-S81.
15. Duhoule, D. 1998. Vertebrate hox gene regulation: clustering and/or colinearity? Curr. Opin. Genet. Dev. 8:514-518.
16. Guazzi, S., R. Lonigro, L. Pintonello, E. Boncinelli, R. Di Lauro, and F. Mavillo. 1994. The thyroid transcription factor-1 gene is a candidate target for regulation hy Hox proteins. EMBO (Eur. Mol. Biol. Organ.) J. 13:3339-3347.
17. Hirschi, K.K., and P.A. D'Amore. 1996. Pericytes in the microvasculature. Cardiovasc. Res. 32:687-698.
18. Holder, N., and R. Klein. 1999. Eph receptors and ephrins: effectors of morphogenesis. Development. 126:2033-2044.
19. Huynh-Do, U., E. Stein, A.A. Lane, H. Liu, D.P. Cerretti, and T.O. Daniel. 1999. Surface densities of ephrin B1 determine EphB-coupled activation of cell attachment through αvβ3 and α5β1 integrins. EMBO (Eur. Mol. Biol. Organ.) J. 18:2165-2173.
20. Jones, F.S., G. Chalepakis, P. Gruss, and G.M. Edelman 1992. Activation of the cytotactin promoter by the homeobox containing gene Evx-1. Proc. Natl. Acad. Sci. USA. 89:2091-2095.
21. Klemke, R.L., S. Cai, A.L. Giannini, P.J. Gallagher, P. De Lanerolle, and D.A. Cheresh. 1997. Regulation of cell motility by mitogen-activated protein kinase. J. Cell Biol. 137:481-492.
22. Kubota, Y., H.K. Kleinman, G.R. Martin, and T.J. Lawley. 1988. Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures. J. Cell Biol. 107:1589-1596.
23. Langston, A.W., and L.J. Gudas. 1994 Retinoic acid and homeobox gene regulation. Curr. Opin. Genet. Dev. 4:550-555.
24. Li, C., and L.J. Gudas. 1996. Murine laminin B1 gene regulation during the retinoic acid and dibutyrl cAMP induced differentiation of embryonic F9 teratocarcinoma stem cells. J. Biol. Chem. 271:6810-6818.
25. Lorentz, O., I. Duluc, A. De Arcangelis, P. Simun-Assman, M. Kedinger, and J.-N. Freund. 1997. Key role of the CDX2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation. J. Cell Biol. 139:1553-1565.
26. Maisonpierre, P.C., C. Suri, P.F. Jones, S. Bartunkova, S.J. Wiegand, C. Radziejewski, D. Compton, J. McClain, T.H. Aldrich, N. Papadopoulos, et al. 1997. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science: 277:55-60.
27. Manley, N.R., and M.R. Capecchi. 1997. Hox group 3 paralogous genes act synerpistically in the formation of somitic and neural crest-derived structures. Dev. Biol. 142:274-288.
28. Pandey, A., H. Shao, R.M. Marks, P. Polverini, and V.M. Dixit. 1995. Role of B61, the ligand for the Eck receptor tyrtisine kinase in TNFα-induced angiogenesis. Science. 268:567-569.
29. Patel, C.V., R. Sharangpam, S. Bandyopadhyay, and P.E. DiCorleto. 1999. Endothelial cells express a novel, tumor necrosis factor alpha-regulated variant of HOXA9. J. Biol. Chem. 274:1415-1422.
30. Savageau, G., U. Thorsteindottir, M.R. Hough, P. Hugo, H.J. Lawrence, C. Largman, and R.K. Humphries. 1997. Overexpression of Hox B3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation. Immunity. 6:13-22.
31. Stelnicki, E.J., J. Arbeit, D.L. Cass, C. Saner, M. Harrison, and C. Largman, 1998. Modulation of the human homebox genes PRX-2 and HOXB13 in scarless fetal wounds. J. Invest. Dermatol. 111:57-63.
32. Stoker, A.W., and M.J. Bissell. 1988. Development of avian sarcoma and leukosis virus-based vector packaging cell lines. J. Virol. 62:1008-1015.
33. Stromblad, S., and D.A. Cheresh. 1996. Cell adhesion and angiogenesis. Trends Cell Biol. 6:462-468.
34. Studer, M., A. Gavalas, H. Marshall, L. Ariza-McNaughton, F.M. Rijli, P. Chambon, and R. Krumlauf. 1998 Genetic interactions between Hox A1 and Hox B1 reveal new roles in regulation of early bindbrain patterning. Development. 125:1025-1036.
35. Wang, H.U., and D.J. Anderson. 1997. Eph family transmembrane ligands can mediate repulsive guidance of trunk neural crest migration and motor axon outgrowth. Neuron. 18:383-396.
36. Werb, Z., T.H. Vu, J.L. Rinkenberger, and L.M. Coussens. 1999. Matrixdegrading proteases and angiogenesis during development and tumor formation. APMIS. 107:11-18.
37. Xu, Y., R.A. Swerlick, N. Sepp, D. Bosse, E.A. Ades, and T.J. Lawley. 1994. Characterization of expression and modulation of cell adhesion molecules on an immortalized dermal microvascular endothelial cell line (HMEC-1). J. Invest. Dermatol. 102:833-837.