VEGF gene delivery to muscle: Potential role for vasculogenesis in adults

Molecular Cell

Volumn 2, Issue 5, 1998, Pages 549-558

  Springer, Matthew L ^b   Chen, Aileen S ^b   Kraft, Peggy E ^b   Bednarski, Mark ^a   Blau, Helen M ^b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; ENDOTHELIAL CELL GROWTH FACTOR; HISTONE ACETYLTRANSFERASE; LYMPHOKINE; SACCHAROMYCES CEREVISIAE PROTEIN; VASCULOTROPIN; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL; ARTICLE; BLOOD; CELL CULTURE; CELL MOTION; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENE TRANSFER; GENE VECTOR; GENETICS; HEMANGIOMA; LIMB; MACROPHAGE; METABOLISM; MOUSE; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY; RETROVIRUS; SKELETAL MUSCLE; VASCULAR ENDOTHELIUM; VASCULARIZATION; WESTERN BLOTTING;

ACETYLTRANSFERASES; ANIMALS; BLOTTING, WESTERN; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTREMITIES; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEMANGIOMA; HISTONE ACETYLTRANSFERASES; LYMPHOKINES; MACROPHAGES; MAGNETIC RESONANCE IMAGING; MICE; MUSCLE, SKELETAL; NEOVASCULARIZATION, PHYSIOLOGIC; RETROVIRIDAE; SACCHAROMYCES CEREVISIAE PROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0032215354     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80154-9     Document Type: Article

References (67)

1. Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G., and Isner, J.M. (1997). Isolation of putative progenitor endothelial cells for angiogenesis. Science 275, 964-967.
2. Austyn, J.M., and Gordon, S. (1981). F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immunol. 11, 805-815.
3. Baldwin, H.S., Shen, H.M., Van, H.C., DeLisser, H.M., Chung, A., Mickanin, C., Trask, T., Kirschbaum, N.E., Newman, P.J., Albelda, S. M., et al. (1994). Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development 120, 2539-2553.
4. Banai, S., Jaklitsch, M.T., Shou, M., Lazarous, D.F., Scheinowitz, M., Biro, S., Epstein, S.E., and Unger, E.F. (1994a). Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs. Circulation 89, 2183-2189.
5. Banai, S., Shweiki, D., Pinson, A., Chandra, M., Lazarovici, G., and Keshet, E. (1994b). Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: implications for coronary angiogenesis. Cardiovasc. Res. 28, 1176-1179.
6. Barr, E., and Leiden, J.M. (1991). Systemic delivery of recombinant proteins by genetically modified myoblasts. Science 254, 1507-1509.
7. Bauters, C., Asahara, T., Zheng, L.P., Takeshita, S., Bunting, S., Ferrara, N., Symes, J.F., and Isner, J.M. (1995). Site-specific therapeutic angiogenesis after systemic administration of vascular endothelial growth factor. J. Vasc. Surg. 21, 314-325.
8. Blau, H.M., and Springer, M.L. (1995). Muscle-mediated gene therapy. New Engl. J. Med. 333, 1554-1556.
9. Bohl, D., Naffakh, N., and Heard, J.M. (1997). Long-term control of erythropoietin secretion by doxycycline in mice transplanted with engineered primary myoblasts. Nat. Med. 3, 299-305.
10. Booth, C.J., and Sundberg, J.P. (1995). Hemangiomas and heman-giosarcomas in inbred laboratory mice. Lab. Anim. Sci. 45, 497-502.
11. Brogi, E., Schatteman, G., Wu, T., Kim, E.A., Varticovski, L., Keyt, B., and Isner, J.M. (1996). Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression. J. Clin. Invest. 97, 469-476.
12. Claffey, K.P., Wilkison, W.O., and Spiegelman, B.M. (1992). Vascular endothelial growth factor. Regulation by cell differentiation and activated second messenger pathways. J. Biol. Chem. 267, 16317-16322.
13. Claffey, K.P., Shih, S.C., Mullen, A., Dziennis, S., Cusick, J.L., Abrams, K.R., Lee, S.W., and Detmar, M. (1998). Identification of a human VPF/VEGF 3′ untranslated region mediating hypoxia-induced mRNA stability. Mol. Biol. Cell 9, 469-481.
14. Conn, G., Soderman, D.D., Schaeffer, M.T., Wile, M., Hatcher, V.B., and Thomas, K.A. (1990). Purification of a glycoprotein vascular endothelial cell mitogen from a rat glioma-derived cell line. Proc. Natl. Acad. Sci. USA 87, 1323-1327.
15. Cotran, R.S., Kumar, V., and Robbins, S.L. (1994). Pathologic Basis of Disease, 5th Edition (Philadelphia, PA: W. B. Saunders Company).
16. Dai, Y., Roman, M., Naviaux, R.K., and Verma, I.M. (1992). Gene therapy via primary myoblasts: long-term expression of factor IX protein following transplantation in vivo. Proc. Natl. Acad. Sci. USA 89, 10892-10895.
17. DeLisser, H.M., Newman, P.J., and Albelda, S.M. (1994). Molecular and functional aspects of PECAM-1/CD31. Immunol. Today 15, 490-495.
18. Detmar, M., Brown, L.F., Berse, B., Jackman, R.W., Elicker, B.M., Dvorak, H.F., and Claffey, K.P. (1997). Hypoxia regulates the expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin. J. Invest. Dermatol. 108, 263-268.
19. Dhawan, J., Pan, L.C., Pavlath, G.K., Travis, M.A., Lanctot, A.M., and Blau, H.M. (1991). Systemic delivery of human growth hormone by injection of genetically engineered myoblasts. Science 254, 1509-1512.
20. Dhawan, J., Rando, R.A., Elson, S.E., Lee, F., Stanley, E.R., and Blau, H.M. (1996). Myoblast-mediated expression of colony stimulating factor-1 (CSF-1) in the cytokine-deficient op/op mouse. Som. Cell Mol. Genet. 22, 363-381.
21. Drake, C.J., and Little, C.D. (1995). Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization. Proc. Natl. Acad. Sci. USA 92, 7657-7661.
22. Fina, L., Molgaard, H.V., Robertson, D., Bradley, N.J., Monaghan, P., Delia, D., Sutherland, D.R., Baker, M.A., and Greaves, M.F. (1990). Expression of the CD34 gene in vascular endothelial cells. Blood 75, 2417-2426.
23. Gussoni, E., Blau, H.M., and Kunkel, L.M. (1997). The fate of individual myoblasts after transplantation into muscles of DMD patients. Nat. Med. 3, 970-977.
24. Harada, K., Friedman, M., Lopez, J.J., Wang, S.Y., Li, J., Prasad, P. V., Pearlman, J.D., Edelman, E.R., Sellke, F.W., and Simons, M. (1996). Vascular endothelial growth factor administration in chronic myocardial ischemia. Am. J. Physiol. 270, H1791-H1802.
25. Hariawala, M.D., Horowitz, J.J., Esakof, D., Sheriff, D.D., Walter, D.H., Keyt, B., Isner, J.M., and Symes, J.F. (1996). VEGF improves myocardial blood flow but produces EDRF-mediated hypotension in porcine hearts. J. Surg. Res. 63, 77-82.
26. Hofmann, A., Nolan, G.P., and Blau, H.M. (1996). Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette. Proc. Natl. Acad. Sci. USA 93, 5185-5190.
27. Horowitz, J.R., Rivard, A., van der Zee, R., Hariawala, M., Sheriff, D.D., Esakof, D.D., Chaudhry, G.M., Symes, J.F., and Isner, J.M. (1997). Vascular endothelial growth factor/vascular permeability factor produces nitric oxide-dependent hypotension. Evidence for a maintenance role in quiescent adult endothelium. Arterioscler. Thromb. Vase. Biol. 17, 2793-2800.
28. Houck, K.A., Leung, D.W., Rowland, A.M., Winer, J., and Ferrara, N. (1992). Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. J. Biol. Chem. 267, 26031-26037.
29. Hughes, S.M., and Blau, H.M. (1992). M uscle fiber pattern is independent of cell lineage in postnatal rodent development. Cell 68, 659-671.
30. Isner, J.M., Pieczek, A., Schainfeld, R., Blair, R., Haley, L., Asahara, T., Rosenfield, K., Razvi, S., Walsh, K., and Symes, J.F. (1996). Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb. Lancet 348, 370-374.
31. Joyner, W.L., and Kern, D.F. (1990). Microvascular permeability to macromolecules and its dynamic modulation. Advanced Drug Delivery Rev. 4, 319-342.
32. Kinoshita, I., Roy, R., Dugre, F.J., Gravel, C., Roy, B., Goulet, M., Asselin, I., and Tremblay, J.P. (1996). Myoblast transplantation in monkeys: control of immune response by FK506. J. Neuropath, and Exp. Neuro. 55, 687-697.
33. Kojimahara, M. (1986). Ultrastructural study of hemangiomas. 4. Cavernous hemangioma of the liver. Acta Pathol. Jpn. 36, 1477-1485.
34. Kringstein, A.M., Rossi, F.M.V., Hofmann, A., and Blau, H.M. (1998). Graded transcriptional response to different concentrations of a single transactivator. Proc. Natl. Acad. Science USA, in press.
35. Lampugnani, M.G., Resnati, M., Raiteri, M., Pigott, R., Piscane, A., Houen, G., Ruco, L.P., and Dejana, E. (1992). A novel endothelial-specific membrane protein is a marker of cell-cell contacts. J. Cell Biol. 118, 1511-1522.
36. Leung, D.W., Cachianes, G., Kuang, W.J., Goeddel, D.V., and Ferrara, N. (1989). Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246, 1306-1309.
37. Lobb, R.R., Key, M.E., Alderman, E.M., and Fett, J.W. (1985). Partial purification and characterization of a vascular permeability factor secreted by a human colon adenocarcinoma cell line. Int. J. Cancer 36, 473-478.
38. Mack, C.A., Patel, S.R., Schwarz, E.A., Zanzonico, P., Hahn, R.T., Ilercil, A., Devereux, R.B., Goldsmith, S.J., Christian, T.F., Sanborn, T.A., et al. (1998). Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart. J. Thorac. Cardiovasc. Surg. 115, 168-177.
39. Magovern, C.J., Mack, C.A., Zhang, J., Rosengart, T.K., Isom, O.W., and Crystal, R.G. (1997). Regional angiogenesis induced in nonischemic tissue by an adenoviral vector expressing vascular endothelial growth factor. Hum. Gene. Ther. 8, 215-227.
40. Mesri, E.A., Federoff, H.J., and Brownlee, M. (1995). Expression of vascular endothelial growth factor from a defective herpes simplex virus type 1 amplicon vector induces angiogenesis in mice. Circ. Res. 76, 161-167.
41. Moore, J.W., and Sholley, M.M. (1985). Comparison of the neovascular effects of stimulated macrophages and neutrophils in autologous rabbit corneas. Am. J. Pathol. 120, 87-98.
42. Mühlhauser, J., Merrill, M.J., Pili, R., Maeda, H., Bacic, M., Bewig, B., Passaniti, A., Edwards, N.A., Crystal, R.G., and Capogrossi, M.C. (1995). VEGF165 expressed by a replication-deficient recombinant adenovirus vector induces angiogenesis in vivo. Circ. Res. 77, 1077-1086.
43. Muller, W.A., Ratti, C.M., McDonnell, S.L., and Cohn, Z.A. (1989). A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions. J. Exp. Med. 170, 399-414.
44. + cells at a diverging point of endothelial and hemopoietic lineages. Development 125, 1747-1757.
45. Pardanaud, L., Yassine, F., and Dieterlen-Lievre, F. (1989). Relationship between vasculogenesis, angiogenesis and haemopoiesis during avian ontogeny. Development 105, 473-485.
46. Pear, W.S., Nolan, G.P., Scott, M.L., and Baltimore, D. (1993). Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA 90, 8392-8396.
47. Plouet, J., Schilling, J., and Gospodarowicz, D. (1989). Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells. EMBO J. 8, 3801-3806.
48. Rand, J.H., Sussman, I.I., Gordon, R.E., Chu, S.V., and Solomon, V. (1980). Localization of factor-VIII-related antigen in human vascular subendothelium. Blood 55, 752-756.
49. Rando, T., and Blau, H.M. (1994). Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy. J. Cell Biol. 125, 1275-1287.
50. Risau, W. (1995). Differentiation of endothelium. FASEB J. 9, 926-933.
51. Risau, W., and Flamme, I. (1995). Vasculogenesis. Annu. Rev. Cell Dev. Biol. 11, 73-91.
52. Senger, D.R., Connolly, D.T., Van de Water, L., Feder, J., and Dvorak, H. F. (1990). Purification and NH2-terminal amino acid sequence of guinea pig tumor-secreted vascular permeability factor. Cancer Res. 50, 1774-1778.
53. Shen, H., Clauss, M., Ryan, J., Schmidt, A.M., Tijburg, P., Borden, L., Connolly, D., Stern, D., and Kao, J. (1993). Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes. Blood 81, 2767-2773.
54. Shi, Q., Rafii, S., Wu, M.H.D., Wijelath, E.S., Yu, C., Ishida, A., Fujita, Y., Kothari, S., Mohle, R., Sauvage, L.R., et al. (1998). Evidence for circulating bone-marrow-derived endothelial cells. Blood 92, 362-367.
55. Skalli, O., Ropraz, P., Trzeciak, A., Benzonana, G., Gillessen, D., and Gabbiani, G. (1986). A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J. Cell Biol. 103, 2787-2796.
56. Springer, M.L., and Blau, H.M. (1997). High efficiency retroviral infection of primary myoblasts. Som. Cell Mol. Genet. 23, 203-209.
57. Springer, M.L., Rando, T.A., and Blau, H.M. (1997). Gene delivery to muscle. In Current Protocols in Human Genetics, A.L Boyle, ed. (New York: John Wiley and Sons), pp. 13.4.1-13.4.19.
58. Sugihara, T., Wadhwa, R., Kaul, S.C., and Mitsui, Y. (1998). A novel alternatively spliced form of murine vascular endothelial growth factor, VEGF 115. J. Biol. Chem. 273, 3033-3038.
59. Takeshita, S., Pu, L.Q., Stein, L.A., Sniderman, A.D., Bunting, S., Ferrara, N., Isner, J.M., and Symes, J.F. (1994a). Intramuscular administration of vascular endothelial growth factor induces dose-dependent collateral artery augmentation in a rabbit model of chronic limb ischemia. Circulation 90, II228-II234.
60. Takeshita, S., Zheng, L.P., Brogi, E., Kearney, M., Pu, L.Q., Bunting, S., Ferrara, N., Symes, J.F., and Isner, J.M. (1994b). Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. J. Clin. Invest. 93, 662-670.
61. Takeshita, S., Tsurumi, Y., Couffinahl, T., Asahara, T., Bauters, C., Symes, J., Ferrara, N., and Isner, J.M. (1996). Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo. Lab. Invest. 75, 487-501.
62. Tassin, A.-M., Paintrand, M., Berger, E.G., and Bornens, M. (1985). The Golgi apparatus remains associated with microtubule organizing centers during myogenesis. J. Cell Biol. 101, 630-638.
63. Tsurumi, Y., Takeshita, S., Chen, D., Kearney, M., Rossow, ST., Passen, J., Horowitz, J.R., Symes, J.F., and Isner, J.M. (1996). Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion. Circulation 94, 3281-3290.
64. Wang, R., Clark, R., and Bautch, V.L. (1992). Embryonic stem cell-derived cystic embryoid bodies form vascular channels: an in vitro model of blood vessel development. Development 114, 303-316.
65. Watt, D.J., Lambert, K., Morgan, J.E., Partridge, T.A., and Sloper, J.C. (1982). Incorporation of donor muscle precursor cells into an area of muscle regeration in the host mouse. J. Neurol. Sci. 57, 319-331.
66. Williams, H.B. (1980). Vascular neoplasms. Clin. Plast. Surg. 7, 397-411.
67. Wilting, J., Christ, B., and Weich, H.A. (1992). The effects of growth factors on the day 13 chorioallantoic membrane (CAM): a study of VEGF165 and PDGF-BB. Anat. Embryol. 186, 251-257.