A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels

Development

Volumn 131, Issue 20, 2004, Pages 5197-5209

  Hallaq, Haifa ^a   Pinter, Emese ^a   Enciso, Josephine ^c   McGrath, James ^a   Zeiss, Caroline ^a   Brueckner, Martina ^a   Madri, Joseph ^a   Jacobs, Harris C ^b   Wilson, Christine M ^a   Vasavada, Hemaxi ^a   Jiang, Xiaobing ^a   Bogue, Clifford W ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIDGEPORT HOSPITAL   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Cardiac morphogenesis; Endocardial cushion; Epithelial mesenchymal transformation; Homeobox; Repressor; Transcription factor; Vasculogenesis; Vegf

Indexed keywords

HOMEODOMAIN PROTEIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 1;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOVASCULAR MALFORMATION; CELL TRANSFORMATION; CONTROLLED STUDY; ENDOCARDIAL CUSHION DEFECT; ENDODERM; EPITHELIUM CELL; GENE MUTATION; HEART DEVELOPMENT; HEART RIGHT VENTRICLE DYSPLASIA; HEART VENTRICLE SEPTUM DEFECT; MESENCHYME CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; TRICUSPID VALVE DISEASE;

ANIMALS; CELL DIFFERENTIATION; EPITHELIUM; HEART; HOMEODOMAIN PROTEINS; MESODERM; MICE; MUTATION; MYOCARDIUM; NEOVASCULARIZATION, PHYSIOLOGIC; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; ZEBRAFISH PROTEINS;

ANIMALIA; MAMMALIA;

EID: 8444234265     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01393     Document Type: Article

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