-
1
-
-
78049402859
-
Molecular signals of epigenetic states
-
Bonasio R., Tu S., Reinberg D. Molecular signals of epigenetic states. Science 2010, 330:612-616.
-
(2010)
Science
, vol.330
, pp. 612-616
-
-
Bonasio, R.1
Tu, S.2
Reinberg, D.3
-
2
-
-
42749087226
-
Highly integrated single-base resolution maps of the epigenome in Arabidopsis
-
Lister R., O'Malley R.C., Tonti-Filippini J., Gregory B.D., Berry C.C., Millar A.H., Ecker J.R. Highly integrated single-base resolution maps of the epigenome in Arabidopsis. Cell 2008, 133:523-536.
-
(2008)
Cell
, vol.133
, pp. 523-536
-
-
Lister, R.1
O'Malley, R.C.2
Tonti-Filippini, J.3
Gregory, B.D.4
Berry, C.C.5
Millar, A.H.6
Ecker, J.R.7
-
3
-
-
42949138450
-
Epigenome sequencing comes of age
-
Zhu J.K. Epigenome sequencing comes of age. Cell 2008, 133:395-397.
-
(2008)
Cell
, vol.133
, pp. 395-397
-
-
Zhu, J.K.1
-
5
-
-
80053144962
-
A decade of exploring the cancer epigenome - biological and translational implications
-
Baylin S.B., Jones P.A. A decade of exploring the cancer epigenome - biological and translational implications. Nat. Rev. Cancer 2011, 11:726-734.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 726-734
-
-
Baylin, S.B.1
Jones, P.A.2
-
6
-
-
82955207588
-
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
-
Wu H., Zhang Y. Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev. 2011, 25:2436-2452.
-
(2011)
Genes Dev.
, vol.25
, pp. 2436-2452
-
-
Wu, H.1
Zhang, Y.2
-
7
-
-
84861912630
-
Programming of DNA methylation patterns
-
Cedar H., Bergman Y. Programming of DNA methylation patterns. Annu. Rev. Biochem. 2012, 81:97-117.
-
(2012)
Annu. Rev. Biochem.
, vol.81
, pp. 97-117
-
-
Cedar, H.1
Bergman, Y.2
-
8
-
-
79955795581
-
Paused RNA polymerase II as a developmental checkpoint
-
Levine M. Paused RNA polymerase II as a developmental checkpoint. Cell 2011, 145:502-511.
-
(2011)
Cell
, vol.145
, pp. 502-511
-
-
Levine, M.1
-
9
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A., Cuddapah S., Cui K., Roh T.Y., Schones D.E., Wang Z., Wei G., Chepelev I., Zhao K. High-resolution profiling of histone methylations in the human genome. Cell 2007, 129:823-837.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
10
-
-
34447098370
-
A chromatin landmark and transcription initiation at most promoters in human cells
-
Guenther M.G., Levine S.S., Boyer L.A., Jaenisch R., Young R.A. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 2007, 130:77-88.
-
(2007)
Cell
, vol.130
, pp. 77-88
-
-
Guenther, M.G.1
Levine, S.S.2
Boyer, L.A.3
Jaenisch, R.4
Young, R.A.5
-
11
-
-
33847065486
-
The epigenomics of cancer
-
Jones P.A., Baylin S.B. The epigenomics of cancer. Cell 2007, 128:683-692.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
12
-
-
70249121045
-
The logic of chromatin architecture and remodelling at promoters
-
Cairns B.R. The logic of chromatin architecture and remodelling at promoters. Nature 2009, 461:193-198.
-
(2009)
Nature
, vol.461
, pp. 193-198
-
-
Cairns, B.R.1
-
13
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M. Epigenetics in cancer. N. Engl. J. Med. 2008, 358:1148-1159.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
14
-
-
77953469917
-
Epigenetics as a unifying principle in the aetiology of complex traits and diseases
-
Petronis A. Epigenetics as a unifying principle in the aetiology of complex traits and diseases. Nature 2010, 465:721-727.
-
(2010)
Nature
, vol.465
, pp. 721-727
-
-
Petronis, A.1
-
15
-
-
58249086425
-
Understanding the words of chromatin regulation
-
Wu J.I., Lessard J., Crabtree G.R. Understanding the words of chromatin regulation. Cell 2009, 136:200-206.
-
(2009)
Cell
, vol.136
, pp. 200-206
-
-
Wu, J.I.1
Lessard, J.2
Crabtree, G.R.3
-
16
-
-
84872050593
-
Interplay between chromatin modifications and paused RNA polymerase II in dynamic transition between stalled and activated genes
-
Liu S., Tao Y. Interplay between chromatin modifications and paused RNA polymerase II in dynamic transition between stalled and activated genes. Biol. Rev. Camb. Philos. Soc. 2012.
-
(2012)
Biol. Rev. Camb. Philos. Soc.
-
-
Liu, S.1
Tao, Y.2
-
17
-
-
84864295824
-
Regulation and function of mammalian DNA methylation patterns: a genomic perspective
-
Wu H., Tao J., Sun Y.E. Regulation and function of mammalian DNA methylation patterns: a genomic perspective. Brief. Funct. Genomics 2012, 11:240-250.
-
(2012)
Brief. Funct. Genomics
, vol.11
, pp. 240-250
-
-
Wu, H.1
Tao, J.2
Sun, Y.E.3
-
18
-
-
23044514626
-
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
-
Weber M., Davies J.J., Wittig D., Oakeley E.J., Haase M., Lam W.L., Schubeler D. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat. Genet. 2005, 37:853-862.
-
(2005)
Nat. Genet.
, vol.37
, pp. 853-862
-
-
Weber, M.1
Davies, J.J.2
Wittig, D.3
Oakeley, E.J.4
Haase, M.5
Lam, W.L.6
Schubeler, D.7
-
19
-
-
31744433660
-
Evidence for an instructive mechanism of de novo methylation in cancer cells
-
Keshet I., Schlesinger Y., Farkash S., Rand E., Hecht M., Segal E., Pikarski E., Young R.A., Niveleau A., Cedar H., Simon I. Evidence for an instructive mechanism of de novo methylation in cancer cells. Nat. Genet. 2006, 38:149-153.
-
(2006)
Nat. Genet.
, vol.38
, pp. 149-153
-
-
Keshet, I.1
Schlesinger, Y.2
Farkash, S.3
Rand, E.4
Hecht, M.5
Segal, E.6
Pikarski, E.7
Young, R.A.8
Niveleau, A.9
Cedar, H.10
Simon, I.11
-
20
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M., Hellmann I., Stadler M.B., Ramos L., Paabo S., Rebhan M., Schubeler D. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat. Genet. 2007, 39:457-466.
-
(2007)
Nat. Genet.
, vol.39
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
Ramos, L.4
Paabo, S.5
Rebhan, M.6
Schubeler, D.7
-
21
-
-
33748629119
-
Genome-wide high-resolution mapping and functional analysis of DNA methylation in Arabidopsis
-
Zhang X., Yazaki J., Sundaresan A., Cokus S., Chan S.W., Chen H., Henderson I.R., Shinn P., Pellegrini M., Jacobsen S.E., Ecker J.R. Genome-wide high-resolution mapping and functional analysis of DNA methylation in Arabidopsis. Cell 2006, 126:1189-1201.
-
(2006)
Cell
, vol.126
, pp. 1189-1201
-
-
Zhang, X.1
Yazaki, J.2
Sundaresan, A.3
Cokus, S.4
Chan, S.W.5
Chen, H.6
Henderson, I.R.7
Shinn, P.8
Pellegrini, M.9
Jacobsen, S.E.10
Ecker, J.R.11
-
22
-
-
58849091905
-
A human B cell methylome at 100-base pair resolution
-
Rauch T.A., Wu X., Zhong X., Riggs A.D., Pfeifer G.P. A human B cell methylome at 100-base pair resolution. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:671-678.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 671-678
-
-
Rauch, T.A.1
Wu, X.2
Zhong, X.3
Riggs, A.D.4
Pfeifer, G.P.5
-
23
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A., Mikkelsen T.S., Gu H., Wernig M., Hanna J., Sivachenko A., Zhang X., Bernstein B.E., Nusbaum C., Jaffe D.B., Gnirke A., Jaenisch R., Lander E.S. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 2008, 454:766-770.
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
Wernig, M.4
Hanna, J.5
Sivachenko, A.6
Zhang, X.7
Bernstein, B.E.8
Nusbaum, C.9
Jaffe, D.B.10
Gnirke, A.11
Jaenisch, R.12
Lander, E.S.13
-
24
-
-
40749109894
-
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning
-
Cokus S.J., Feng S., Zhang X., Chen Z., Merriman B., Haudenschild C.D., Pradhan S., Nelson S.F., Pellegrini M., Jacobsen S.E. Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature 2008, 452:215-219.
-
(2008)
Nature
, vol.452
, pp. 215-219
-
-
Cokus, S.J.1
Feng, S.2
Zhang, X.3
Chen, Z.4
Merriman, B.5
Haudenschild, C.D.6
Pradhan, S.7
Nelson, S.F.8
Pellegrini, M.9
Jacobsen, S.E.10
-
25
-
-
77952355762
-
Genome-wide evolutionary analysis of eukaryotic DNA methylation
-
Zemach A., McDaniel I.E., Silva P., Zilberman D. Genome-wide evolutionary analysis of eukaryotic DNA methylation. Science 2010, 328:916-919.
-
(2010)
Science
, vol.328
, pp. 916-919
-
-
Zemach, A.1
McDaniel, I.E.2
Silva, P.3
Zilberman, D.4
-
26
-
-
77952734605
-
Conservation and divergence of methylation patterning in plants and animals
-
Feng S., Cokus S.J., Zhang X., Chen P.Y., Bostick M., Goll M.G., Hetzel J., Jain J., Strauss S.H., Halpern M.E., Ukomadu C., Sadler K.C., Pradhan S., Pellegrini M., Jacobsen S.E. Conservation and divergence of methylation patterning in plants and animals. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:8689-8694.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 8689-8694
-
-
Feng, S.1
Cokus, S.J.2
Zhang, X.3
Chen, P.Y.4
Bostick, M.5
Goll, M.G.6
Hetzel, J.7
Jain, J.8
Strauss, S.H.9
Halpern, M.E.10
Ukomadu, C.11
Sadler, K.C.12
Pradhan, S.13
Pellegrini, M.14
Jacobsen, S.E.15
-
27
-
-
78649969065
-
The DNA methylome of human peripheral blood mononuclear cells
-
Li Y., Zhu J., Tian G., Li N., Li Q., Ye M., Zheng H., Yu J., Wu H., Sun J., Zhang H., Chen Q., Luo R., Chen M., He Y., Jin X., Zhang Q., Yu C., Zhou G., Huang Y., Cao H., Zhou X., Guo S., Hu X., Li X., Kristiansen K., Bolund L., Xu J., Wang W., Yang H., Wang J., Li R., Beck S., Zhang X. The DNA methylome of human peripheral blood mononuclear cells. PLoS Biol. 2010, 8:e1000533.
-
(2010)
PLoS Biol.
, vol.8
-
-
Li, Y.1
Zhu, J.2
Tian, G.3
Li, N.4
Li, Q.5
Ye, M.6
Zheng, H.7
Yu, J.8
Wu, H.9
Sun, J.10
Zhang, H.11
Chen, Q.12
Luo, R.13
Chen, M.14
He, Y.15
Jin, X.16
Zhang, Q.17
Yu, C.18
Zhou, G.19
Huang, Y.20
Cao, H.21
Zhou, X.22
Guo, S.23
Hu, X.24
Li, X.25
Kristiansen, K.26
Bolund, L.27
Xu, J.28
Wang, W.29
Yang, H.30
Wang, J.31
Li, R.32
Beck, S.33
Zhang, X.34
more..
-
28
-
-
79954993753
-
Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences
-
Tao Y., Xi S., Shan J., Maunakea A., Che A., Briones V., Lee E.Y., Geiman T., Huang J., Stephens R., Leighty R.M., Zhao K., Muegge K. Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:5626-5631.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 5626-5631
-
-
Tao, Y.1
Xi, S.2
Shan, J.3
Maunakea, A.4
Che, A.5
Briones, V.6
Lee, E.Y.7
Geiman, T.8
Huang, J.9
Stephens, R.10
Leighty, R.M.11
Zhao, K.12
Muegge, K.13
-
29
-
-
78649459828
-
Targets and dynamics of promoter DNA methylation during early mouse development
-
Borgel J., Guibert S., Li Y., Chiba H., Schubeler D., Sasaki H., Forne T., Weber M. Targets and dynamics of promoter DNA methylation during early mouse development. Nat. Genet. 2010, 42:1093-1100.
-
(2010)
Nat. Genet.
, vol.42
, pp. 1093-1100
-
-
Borgel, J.1
Guibert, S.2
Li, Y.3
Chiba, H.4
Schubeler, D.5
Sasaki, H.6
Forne, T.7
Weber, M.8
-
30
-
-
80555125018
-
Comparative methylomics reveals gene-body H3K36me3 in Drosophila predicts DNA methylation and CpG landscapes in other invertebrates
-
Nanty L., Carbajosa G., Heap G.A., Ratnieks F., van Heel D.A., Down T.A., Rakyan V.K. Comparative methylomics reveals gene-body H3K36me3 in Drosophila predicts DNA methylation and CpG landscapes in other invertebrates. Genome Res. 2011, 21:1841-1850.
-
(2011)
Genome Res.
, vol.21
, pp. 1841-1850
-
-
Nanty, L.1
Carbajosa, G.2
Heap, G.A.3
Ratnieks, F.4
van Heel, D.A.5
Down, T.A.6
Rakyan, V.K.7
-
31
-
-
51649129596
-
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
-
Mohn F., Weber M., Rebhan M., Roloff T.C., Richter J., Stadler M.B., Bibel M., Schubeler D. Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol. Cell 2008, 30:755-766.
-
(2008)
Mol. Cell
, vol.30
, pp. 755-766
-
-
Mohn, F.1
Weber, M.2
Rebhan, M.3
Roloff, T.C.4
Richter, J.5
Stadler, M.B.6
Bibel, M.7
Schubeler, D.8
-
32
-
-
84883798471
-
PcG proteins, DNA methylation, and gene repression by chromatin looping
-
Tiwari V.K., McGarvey K.M., Licchesi J.D., Ohm J.E., Herman J.G., Schubeler D., Baylin S.B. PcG proteins, DNA methylation, and gene repression by chromatin looping. PLoS Biol. 2008, 6:2911-2927.
-
(2008)
PLoS Biol.
, vol.6
, pp. 2911-2927
-
-
Tiwari, V.K.1
McGarvey, K.M.2
Licchesi, J.D.3
Ohm, J.E.4
Herman, J.G.5
Schubeler, D.6
Baylin, S.B.7
-
33
-
-
77954504873
-
Conserved role of intragenic DNA methylation in regulating alternative promoters
-
Maunakea A.K., Nagarajan R.P., Bilenky M., Ballinger T.J., D'Souza C., Fouse S.D., Johnson B.E., Hong C., Nielsen C., Zhao Y., Turecki G., Delaney A., Varhol R., Thiessen N., Shchors K., Heine V.M., Rowitch D.H., Xing X., Fiore C., Schillebeeckx M., Jones S.J., Haussler D., Marra M.A., Hirst M., Wang T., Costello J.F. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature 2010, 466:253-257.
-
(2010)
Nature
, vol.466
, pp. 253-257
-
-
Maunakea, A.K.1
Nagarajan, R.P.2
Bilenky, M.3
Ballinger, T.J.4
D'Souza, C.5
Fouse, S.D.6
Johnson, B.E.7
Hong, C.8
Nielsen, C.9
Zhao, Y.10
Turecki, G.11
Delaney, A.12
Varhol, R.13
Thiessen, N.14
Shchors, K.15
Heine, V.M.16
Rowitch, D.H.17
Xing, X.18
Fiore, C.19
Schillebeeckx, M.20
Jones, S.J.21
Haussler, D.22
Marra, M.A.23
Hirst, M.24
Wang, T.25
Costello, J.F.26
more..
-
34
-
-
75749142980
-
A role for the elongator complex in zygotic paternal genome demethylation
-
Okada Y., Yamagata K., Hong K., Wakayama T., Zhang Y. A role for the elongator complex in zygotic paternal genome demethylation. Nature 2010, 463:554-558.
-
(2010)
Nature
, vol.463
, pp. 554-558
-
-
Okada, Y.1
Yamagata, K.2
Hong, K.3
Wakayama, T.4
Zhang, Y.5
-
35
-
-
55549141877
-
Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks
-
Zilberman D., Coleman-Derr D., Ballinger T., Henikoff S. Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks. Nature 2008, 456:125-129.
-
(2008)
Nature
, vol.456
, pp. 125-129
-
-
Zilberman, D.1
Coleman-Derr, D.2
Ballinger, T.3
Henikoff, S.4
-
36
-
-
77954659099
-
Relationship between nucleosome positioning and DNA methylation
-
Chodavarapu R.K., Feng S., Bernatavichute Y.V., Chen P.Y., Stroud H., Yu Y., Hetzel J.A., Kuo F., Kim J., Cokus S.J., Casero D., Bernal M., Huijser P., Clark A.T., Kramer U., Merchant S.S., Zhang X., Jacobsen S.E., Pellegrini M. Relationship between nucleosome positioning and DNA methylation. Nature 2010, 466:388-392.
-
(2010)
Nature
, vol.466
, pp. 388-392
-
-
Chodavarapu, R.K.1
Feng, S.2
Bernatavichute, Y.V.3
Chen, P.Y.4
Stroud, H.5
Yu, Y.6
Hetzel, J.A.7
Kuo, F.8
Kim, J.9
Cokus, S.J.10
Casero, D.11
Bernal, M.12
Huijser, P.13
Clark, A.T.14
Kramer, U.15
Merchant, S.S.16
Zhang, X.17
Jacobsen, S.E.18
Pellegrini, M.19
-
37
-
-
80054718602
-
Spontaneous epigenetic variation in the Arabidopsis thaliana methylome
-
Becker C., Hagmann J., Muller J., Koenig D., Stegle O., Borgwardt K., Weigel D. Spontaneous epigenetic variation in the Arabidopsis thaliana methylome. Nature 2011, 480:245-249.
-
(2011)
Nature
, vol.480
, pp. 245-249
-
-
Becker, C.1
Hagmann, J.2
Muller, J.3
Koenig, D.4
Stegle, O.5
Borgwardt, K.6
Weigel, D.7
-
38
-
-
80054994283
-
Identification of genetic elements that autonomously determine DNA methylation states
-
Lienert F., Wirbelauer C., Som I., Dean A., Mohn F., Schubeler D. Identification of genetic elements that autonomously determine DNA methylation states. Nat. Genet. 2011, 43:1091-1097.
-
(2011)
Nat. Genet.
, vol.43
, pp. 1091-1097
-
-
Lienert, F.1
Wirbelauer, C.2
Som, I.3
Dean, A.4
Mohn, F.5
Schubeler, D.6
-
39
-
-
84355163093
-
DNA-binding factors shape the mouse methylome at distal regulatory regions
-
Stadler M.B., Murr R., Burger L., Ivanek R., Lienert F., Scholer A., van Nimwegen E., Wirbelauer C., Oakeley E.J., Gaidatzis D., Tiwari V.K., Schubeler D. DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature 2011, 480:490-495.
-
(2011)
Nature
, vol.480
, pp. 490-495
-
-
Stadler, M.B.1
Murr, R.2
Burger, L.3
Ivanek, R.4
Lienert, F.5
Scholer, A.6
van Nimwegen, E.7
Wirbelauer, C.8
Oakeley, E.J.9
Gaidatzis, D.10
Tiwari, V.K.11
Schubeler, D.12
-
40
-
-
84859910536
-
A unique regulatory phase of DNA methylation in the early mammalian embryo
-
Smith Z.D., Chan M.M., Mikkelsen T.S., Gu H., Gnirke A., Regev A., Meissner A. A unique regulatory phase of DNA methylation in the early mammalian embryo. Nature 2012, 484:339-344.
-
(2012)
Nature
, vol.484
, pp. 339-344
-
-
Smith, Z.D.1
Chan, M.M.2
Mikkelsen, T.S.3
Gu, H.4
Gnirke, A.5
Regev, A.6
Meissner, A.7
-
41
-
-
80052937538
-
Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates
-
Molaro A., Hodges E., Fang F., Song Q., McCombie W.R., Hannon G.J., Smith A.D. Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates. Cell 2011, 146:1029-1041.
-
(2011)
Cell
, vol.146
, pp. 1029-1041
-
-
Molaro, A.1
Hodges, E.2
Fang, F.3
Song, Q.4
McCombie, W.R.5
Hannon, G.J.6
Smith, A.D.7
-
42
-
-
79551677421
-
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines
-
Bock C., Kiskinis E., Verstappen G., Gu H., Boulting G., Smith Z.D., Ziller M., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K., Meissner A. Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell 2011, 144:439-452.
-
(2011)
Cell
, vol.144
, pp. 439-452
-
-
Bock, C.1
Kiskinis, E.2
Verstappen, G.3
Gu, H.4
Boulting, G.5
Smith, Z.D.6
Ziller, M.7
Croft, G.F.8
Amoroso, M.W.9
Oakley, D.H.10
Gnirke, A.11
Eggan, K.12
Meissner, A.13
-
43
-
-
84861977900
-
Comparative epigenomic annotation of regulatory DNA
-
Xiao S., Xie D., Cao X., Yu P., Xing X., Chen C.C., Musselman M., Xie M., West F.D., Lewin H.A., Wang T., Zhong S. Comparative epigenomic annotation of regulatory DNA. Cell 2012, 149:1381-1392.
-
(2012)
Cell
, vol.149
, pp. 1381-1392
-
-
Xiao, S.1
Xie, D.2
Cao, X.3
Yu, P.4
Xing, X.5
Chen, C.C.6
Musselman, M.7
Xie, M.8
West, F.D.9
Lewin, H.A.10
Wang, T.11
Zhong, S.12
-
44
-
-
84860808258
-
Genomic landscape of human allele-specific DNA methylation
-
Fang F., Hodges E., Molaro A., Dean M., Hannon G.J., Smith A.D. Genomic landscape of human allele-specific DNA methylation. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:7332-7337.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 7332-7337
-
-
Fang, F.1
Hodges, E.2
Molaro, A.3
Dean, M.4
Hannon, G.J.5
Smith, A.D.6
-
45
-
-
79957577720
-
Primate CpG islands are maintained by heterogeneous evolutionary regimes involving minimal selection
-
Cohen N.M., Kenigsberg E., Tanay A. Primate CpG islands are maintained by heterogeneous evolutionary regimes involving minimal selection. Cell 2011, 145:773-786.
-
(2011)
Cell
, vol.145
, pp. 773-786
-
-
Cohen, N.M.1
Kenigsberg, E.2
Tanay, A.3
-
46
-
-
84856555311
-
A DNA methylation fingerprint of 1628 human samples
-
Fernandez A.F., Assenov Y., Martin-Subero J.I., Balint B., Siebert R., Taniguchi H., Yamamoto H., Hidalgo M., Tan A.C., Galm O., Ferrer I., Sanchez-Cespedes M., Villanueva A., Carmona J., Sanchez-Mut J.V., Berdasco M., Moreno V., Capella G., Monk D., Ballestar E., Ropero S., Martinez R., Sanchez-Carbayo M., Prosper F., Agirre X., Fraga M.F., Grana O., Perez-Jurado L., Mora J., Puig S., Prat J., Badimon L., Puca A.A., Meltzer S.J., Lengauer T., Bridgewater J., Bock C., Esteller M. A DNA methylation fingerprint of 1628 human samples. Genome Res. 2012, 22:407-419.
-
(2012)
Genome Res.
, vol.22
, pp. 407-419
-
-
Fernandez, A.F.1
Assenov, Y.2
Martin-Subero, J.I.3
Balint, B.4
Siebert, R.5
Taniguchi, H.6
Yamamoto, H.7
Hidalgo, M.8
Tan, A.C.9
Galm, O.10
Ferrer, I.11
Sanchez-Cespedes, M.12
Villanueva, A.13
Carmona, J.14
Sanchez-Mut, J.V.15
Berdasco, M.16
Moreno, V.17
Capella, G.18
Monk, D.19
Ballestar, E.20
Ropero, S.21
Martinez, R.22
Sanchez-Carbayo, M.23
Prosper, F.24
Agirre, X.25
Fraga, M.F.26
Grana, O.27
Perez-Jurado, L.28
Mora, J.29
Puig, S.30
Prat, J.31
Badimon, L.32
Puca, A.A.33
Meltzer, S.J.34
Lengauer, T.35
Bridgewater, J.36
Bock, C.37
Esteller, M.38
more..
-
47
-
-
77956902023
-
Comprehensive methylome map of lineage commitment from haematopoietic progenitors
-
Ji H., Ehrlich L.I., Seita J., Murakami P., Doi A., Lindau P., Lee H., Aryee M.J., Irizarry R.A., Kim K., Rossi D.J., Inlay M.A., Serwold T., Karsunky H., Ho L., Daley G.Q., Weissman I.L., Feinberg A.P. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature 2010, 467:338-342.
-
(2010)
Nature
, vol.467
, pp. 338-342
-
-
Ji, H.1
Ehrlich, L.I.2
Seita, J.3
Murakami, P.4
Doi, A.5
Lindau, P.6
Lee, H.7
Aryee, M.J.8
Irizarry, R.A.9
Kim, K.10
Rossi, D.J.11
Inlay, M.A.12
Serwold, T.13
Karsunky, H.14
Ho, L.15
Daley, G.Q.16
Weissman, I.L.17
Feinberg, A.P.18
-
48
-
-
79959872458
-
Cell type-specific DNA methylation at intragenic CpG islands in the immune system
-
Deaton A.M., Webb S., Kerr A.R., Illingworth R.S., Guy J., Andrews R., Bird A. Cell type-specific DNA methylation at intragenic CpG islands in the immune system. Genome Res. 2011, 21:1074-1086.
-
(2011)
Genome Res.
, vol.21
, pp. 1074-1086
-
-
Deaton, A.M.1
Webb, S.2
Kerr, A.R.3
Illingworth, R.S.4
Guy, J.5
Andrews, R.6
Bird, A.7
-
49
-
-
77951116072
-
CpG islands influence chromatin structure via the CpG-binding protein Cfp1
-
Thomson J.P., Skene P.J., Selfridge J., Clouaire T., Guy J., Webb S., Kerr A.R., Deaton A., Andrews R., James K.D., Turner D.J., Illingworth R., Bird A. CpG islands influence chromatin structure via the CpG-binding protein Cfp1. Nature 2010, 464:1082-1086.
-
(2010)
Nature
, vol.464
, pp. 1082-1086
-
-
Thomson, J.P.1
Skene, P.J.2
Selfridge, J.3
Clouaire, T.4
Guy, J.5
Webb, S.6
Kerr, A.R.7
Deaton, A.8
Andrews, R.9
James, K.D.10
Turner, D.J.11
Illingworth, R.12
Bird, A.13
-
50
-
-
78049419464
-
Orphan CpG islands identify numerous conserved promoters in the mammalian genome
-
Illingworth R.S., Gruenewald-Schneider U., Webb S., Kerr A.R., James K.D., Turner D.J., Smith C., Harrison D.J., Andrews R., Bird A.P. Orphan CpG islands identify numerous conserved promoters in the mammalian genome. PLoS Genet. 2010, 6.
-
(2010)
PLoS Genet.
, vol.6
-
-
Illingworth, R.S.1
Gruenewald-Schneider, U.2
Webb, S.3
Kerr, A.R.4
James, K.D.5
Turner, D.J.6
Smith, C.7
Harrison, D.J.8
Andrews, R.9
Bird, A.P.10
-
51
-
-
77954842322
-
Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
-
Wu H., Coskun V., Tao J., Xie W., Ge W., Yoshikawa K., Li E., Zhang Y., Sun Y.E. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 2010, 329:444-448.
-
(2010)
Science
, vol.329
, pp. 444-448
-
-
Wu, H.1
Coskun, V.2
Tao, J.3
Xie, W.4
Ge, W.5
Yoshikawa, K.6
Li, E.7
Zhang, Y.8
Sun, Y.E.9
-
52
-
-
81055130253
-
Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression
-
Gao Q., Steine E.J., Barrasa M.I., Hockemeyer D., Pawlak M., Fu D., Reddy S., Bell G.W., Jaenisch R. Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:18061-18066.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 18061-18066
-
-
Gao, Q.1
Steine, E.J.2
Barrasa, M.I.3
Hockemeyer, D.4
Pawlak, M.5
Fu, D.6
Reddy, S.7
Bell, G.W.8
Jaenisch, R.9
-
53
-
-
84555207349
-
Dnmt3a is essential for hematopoietic stem cell differentiation
-
Challen G.A., Sun D., Jeong M., Luo M., Jelinek J., Berg J.S., Bock C., Vasanthakumar A., Gu H., Xi Y., Liang S., Lu Y., Darlington G.J., Meissner A., Issa J.P., Godley L.A., Li W., Goodell M.A. Dnmt3a is essential for hematopoietic stem cell differentiation. Nat. Genet. 2012, 44:23-31.
-
(2012)
Nat. Genet.
, vol.44
, pp. 23-31
-
-
Challen, G.A.1
Sun, D.2
Jeong, M.3
Luo, M.4
Jelinek, J.5
Berg, J.S.6
Bock, C.7
Vasanthakumar, A.8
Gu, H.9
Xi, Y.10
Liang, S.11
Lu, Y.12
Darlington, G.J.13
Meissner, A.14
Issa, J.P.15
Godley, L.A.16
Li, W.17
Goodell, M.A.18
-
54
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R., Pelizzola M., Dowen R.H., Hawkins R.D., Hon G., Tonti-Filippini J., Nery J.R., Lee L., Ye Z., Ngo Q.M., Edsall L., Antosiewicz-Bourget J., Stewart R., Ruotti V., Millar A.H., Thomson J.A., Ren B., Ecker J.R. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009, 462:315-322.
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
Hawkins, R.D.4
Hon, G.5
Tonti-Filippini, J.6
Nery, J.R.7
Lee, L.8
Ye, Z.9
Ngo, Q.M.10
Edsall, L.11
Antosiewicz-Bourget, J.12
Stewart, R.13
Ruotti, V.14
Millar, A.H.15
Thomson, J.A.16
Ren, B.17
Ecker, J.R.18
-
55
-
-
77649267695
-
Dynamic changes in the human methylome during differentiation
-
Laurent L., Wong E., Li G., Huynh T., Tsirigos A., Ong C.T., Low H.M., Kin Sung K.W., Rigoutsos I., Loring J., Wei C.L. Dynamic changes in the human methylome during differentiation. Genome Res. 2010, 20:320-331.
-
(2010)
Genome Res.
, vol.20
, pp. 320-331
-
-
Laurent, L.1
Wong, E.2
Li, G.3
Huynh, T.4
Tsirigos, A.5
Ong, C.T.6
Low, H.M.7
Kin Sung, K.W.8
Rigoutsos, I.9
Loring, J.10
Wei, C.L.11
-
56
-
-
84855281409
-
Genomic distribution and inter-sample variation of non-CpG methylation across human cell types
-
Ziller M.J., Muller F., Liao J., Zhang Y., Gu H., Bock C., Boyle P., Epstein C.B., Bernstein B.E., Lengauer T., Gnirke A., Meissner A. Genomic distribution and inter-sample variation of non-CpG methylation across human cell types. PLoS Genet. 2011, 7:e1002389.
-
(2011)
PLoS Genet.
, vol.7
-
-
Ziller, M.J.1
Muller, F.2
Liao, J.3
Zhang, Y.4
Gu, H.5
Bock, C.6
Boyle, P.7
Epstein, C.B.8
Bernstein, B.E.9
Lengauer, T.10
Gnirke, A.11
Meissner, A.12
-
57
-
-
69149087790
-
Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density
-
Barres R., Osler M.E., Yan J., Rune A., Fritz T., Caidahl K., Krook A., Zierath J.R. Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density. Cell Metab. 2009, 10:189-198.
-
(2009)
Cell Metab.
, vol.10
, pp. 189-198
-
-
Barres, R.1
Osler, M.E.2
Yan, J.3
Rune, A.4
Fritz, T.5
Caidahl, K.6
Krook, A.7
Zierath, J.R.8
-
58
-
-
80053572636
-
Evidence for non-CpG methylation in mammals
-
Yan J., Zierath J.R., Barres R. Evidence for non-CpG methylation in mammals. Exp. Cell Res. 2011, 317:2555-2561.
-
(2011)
Exp. Cell Res.
, vol.317
, pp. 2555-2561
-
-
Yan, J.1
Zierath, J.R.2
Barres, R.3
-
60
-
-
81055139701
-
Global DNA demethylation during mouse erythropoiesis in vivo
-
Shearstone J.R., Pop R., Bock C., Boyle P., Meissner A., Socolovsky M. Global DNA demethylation during mouse erythropoiesis in vivo. Science 2011, 334:799-802.
-
(2011)
Science
, vol.334
, pp. 799-802
-
-
Shearstone, J.R.1
Pop, R.2
Bock, C.3
Boyle, P.4
Meissner, A.5
Socolovsky, M.6
-
61
-
-
40449104358
-
Transient cyclical methylation of promoter DNA
-
Kangaspeska S., Stride B., Metivier R., Polycarpou-Schwarz M., Ibberson D., Carmouche R.P., Benes V., Gannon F., Reid G. Transient cyclical methylation of promoter DNA. Nature 2008, 452:112-115.
-
(2008)
Nature
, vol.452
, pp. 112-115
-
-
Kangaspeska, S.1
Stride, B.2
Metivier, R.3
Polycarpou-Schwarz, M.4
Ibberson, D.5
Carmouche, R.P.6
Benes, V.7
Gannon, F.8
Reid, G.9
-
62
-
-
40449123137
-
Cyclical DNA methylation of a transcriptionally active promoter
-
Metivier R., Gallais R., Tiffoche C., Le Peron C., Jurkowska R.Z., Carmouche R.P., Ibberson D., Barath P., Demay F., Reid G., Benes V., Jeltsch A., Gannon F., Salbert G. Cyclical DNA methylation of a transcriptionally active promoter. Nature 2008, 452:45-50.
-
(2008)
Nature
, vol.452
, pp. 45-50
-
-
Metivier, R.1
Gallais, R.2
Tiffoche, C.3
Le Peron, C.4
Jurkowska, R.Z.5
Carmouche, R.P.6
Ibberson, D.7
Barath, P.8
Demay, F.9
Reid, G.10
Benes, V.11
Jeltsch, A.12
Gannon, F.13
Salbert, G.14
-
63
-
-
33846933274
-
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
-
Barreto G., Schafer A., Marhold J., Stach D., Swaminathan S.K., Handa V., Doderlein G., Maltry N., Wu W., Lyko F., Niehrs C. Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 2007, 445:671-675.
-
(2007)
Nature
, vol.445
, pp. 671-675
-
-
Barreto, G.1
Schafer, A.2
Marhold, J.3
Stach, D.4
Swaminathan, S.K.5
Handa, V.6
Doderlein, G.7
Maltry, N.8
Wu, W.9
Lyko, F.10
Niehrs, C.11
-
64
-
-
60749094831
-
Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis
-
Ma D.K., Jang M.H., Guo J.U., Kitabatake Y., Chang M.L., Pow-Anpongkul N., Flavell R.A., Lu B., Ming G.L., Song H. Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 2009, 323:1074-1077.
-
(2009)
Science
, vol.323
, pp. 1074-1077
-
-
Ma, D.K.1
Jang, M.H.2
Guo, J.U.3
Kitabatake, Y.4
Chang, M.L.5
Pow-Anpongkul, N.6
Flavell, R.A.7
Lu, B.8
Ming, G.L.9
Song, H.10
-
65
-
-
77954345408
-
Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway
-
Hajkova P., Jeffries S.J., Lee C., Miller N., Jackson S.P., Surani M.A. Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science 2010, 329:78-82.
-
(2010)
Science
, vol.329
, pp. 78-82
-
-
Hajkova, P.1
Jeffries, S.J.2
Lee, C.3
Miller, N.4
Jackson, S.P.5
Surani, M.A.6
-
66
-
-
77249148019
-
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
-
Popp C., Dean W., Feng S., Cokus S.J., Andrews S., Pellegrini M., Jacobsen S.E., Reik W. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 2010, 463:1101-1105.
-
(2010)
Nature
, vol.463
, pp. 1101-1105
-
-
Popp, C.1
Dean, W.2
Feng, S.3
Cokus, S.J.4
Andrews, S.5
Pellegrini, M.6
Jacobsen, S.E.7
Reik, W.8
-
67
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino S., Xu J., Sannai M., Moore R., Caretti E., Cigliano A., Le Coz M., Devarajan K., Wessels A., Soprano D., Abramowitz L.K., Bartolomei M.S., Rambow F., Bassi M.R., Bruno T., Fanciulli M., Renner C., Klein-Szanto A.J., Matsumoto Y., Kobi D., Davidson I., Alberti C., Larue L., Bellacosa A. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 2011, 146:67-79.
-
(2011)
Cell
, vol.146
, pp. 67-79
-
-
Cortellino, S.1
Xu, J.2
Sannai, M.3
Moore, R.4
Caretti, E.5
Cigliano, A.6
Le Coz, M.7
Devarajan, K.8
Wessels, A.9
Soprano, D.10
Abramowitz, L.K.11
Bartolomei, M.S.12
Rambow, F.13
Bassi, M.R.14
Bruno, T.15
Fanciulli, M.16
Renner, C.17
Klein-Szanto, A.J.18
Matsumoto, Y.19
Kobi, D.20
Davidson, I.21
Alberti, C.22
Larue, L.23
Bellacosa, A.24
more..
-
68
-
-
79951810964
-
Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability
-
Cortazar D., Kunz C., Selfridge J., Lettieri T., Saito Y., MacDougall E., Wirz A., Schuermann D., Jacobs A.L., Siegrist F., Steinacher R., Jiricny J., Bird A., Schar P. Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability. Nature 2011, 470:419-423.
-
(2011)
Nature
, vol.470
, pp. 419-423
-
-
Cortazar, D.1
Kunz, C.2
Selfridge, J.3
Lettieri, T.4
Saito, Y.5
MacDougall, E.6
Wirz, A.7
Schuermann, D.8
Jacobs, A.L.9
Siegrist, F.10
Steinacher, R.11
Jiricny, J.12
Bird, A.13
Schar, P.14
-
69
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis S., Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 2009, 324:929-930.
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
70
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M., Koh K.P., Shen Y., Pastor W.A., Bandukwala H., Brudno Y., Agarwal S., Iyer L.M., Liu D.R., Aravind L., Rao A. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 2009, 324:930-935.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
Rao, A.11
-
71
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
Guo J.U., Su Y., Zhong C., Ming G.L., Song H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 2011, 145:423-434.
-
(2011)
Cell
, vol.145
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
72
-
-
80052933429
-
DNA demethylation dynamics
-
Bhutani N., Burns D.M., Blau H.M. DNA demethylation dynamics. Cell 2011, 146:866-872.
-
(2011)
Cell
, vol.146
, pp. 866-872
-
-
Bhutani, N.1
Burns, D.M.2
Blau, H.M.3
-
73
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams K., Christensen J., Pedersen M.T., Johansen J.V., Cloos P.A., Rappsilber J., Helin K. TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 2011, 473:343-348.
-
(2011)
Nature
, vol.473
, pp. 343-348
-
-
Williams, K.1
Christensen, J.2
Pedersen, M.T.3
Johansen, J.V.4
Cloos, P.A.5
Rappsilber, J.6
Helin, K.7
-
74
-
-
79956323623
-
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz G., Branco M.R., Seisenberger S., Santos F., Krueger F., Hore T.A., Marques C.J., Andrews S., Reik W. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 2011, 473:398-402.
-
(2011)
Nature
, vol.473
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
Santos, F.4
Krueger, F.5
Hore, T.A.6
Marques, C.J.7
Andrews, S.8
Reik, W.9
-
75
-
-
79956292024
-
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
-
Wu H., D'Alessio A.C., Ito S., Xia K., Wang Z., Cui K., Zhao K., Sun Y.E., Zhang Y. Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 2011, 473:389-393.
-
(2011)
Nature
, vol.473
, pp. 389-393
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Xia, K.4
Wang, Z.5
Cui, K.6
Zhao, K.7
Sun, Y.E.8
Zhang, Y.9
-
76
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
Pastor W.A., Pape U.J., Huang Y., Henderson H.R., Lister R., Ko M., McLoughlin E.M., Brudno Y., Mahapatra S., Kapranov P., Tahiliani M., Daley G.Q., Liu X.S., Ecker J.R., Milos P.M., Agarwal S., Rao A. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 2011, 473:394-397.
-
(2011)
Nature
, vol.473
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
Henderson, H.R.4
Lister, R.5
Ko, M.6
McLoughlin, E.M.7
Brudno, Y.8
Mahapatra, S.9
Kapranov, P.10
Tahiliani, M.11
Daley, G.Q.12
Liu, X.S.13
Ecker, J.R.14
Milos, P.M.15
Agarwal, S.16
Rao, A.17
-
77
-
-
78650175023
-
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
-
Ko M., Huang Y., Jankowska A.M., Pape U.J., Tahiliani M., Bandukwala H.S., An J., Lamperti E.D., Koh K.P., Ganetzky R., Liu X.S., Aravind L., Agarwal S., Maciejewski J.P., Rao A. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature 2010, 468:839-843.
-
(2010)
Nature
, vol.468
, pp. 839-843
-
-
Ko, M.1
Huang, Y.2
Jankowska, A.M.3
Pape, U.J.4
Tahiliani, M.5
Bandukwala, H.S.6
An, J.7
Lamperti, E.D.8
Koh, K.P.9
Ganetzky, R.10
Liu, X.S.11
Aravind, L.12
Agarwal, S.13
Maciejewski, J.P.14
Rao, A.15
-
78
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito S., D'Alessio A.C., Taranova O.V., Hong K., Sowers L.C., Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 2010, 466:1129-1133.
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
79
-
-
79960062301
-
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
-
Quivoron C., Couronne L., Della Valle V., Lopez C.K., Plo I., Wagner-Ballon O., Do Cruzeiro M., Delhommeau F., Arnulf B., Stern M.H., Godley L., Opolon P., Tilly H., Solary E., Duffourd Y., Dessen P., Merle-Beral H., Nguyen-Khac F., Fontenay M., Vainchenker W., Bastard C., Mercher T., Bernard O.A. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 2011, 20:25-38.
-
(2011)
Cancer Cell
, vol.20
, pp. 25-38
-
-
Quivoron, C.1
Couronne, L.2
Della Valle, V.3
Lopez, C.K.4
Plo, I.5
Wagner-Ballon, O.6
Do Cruzeiro, M.7
Delhommeau, F.8
Arnulf, B.9
Stern, M.H.10
Godley, L.11
Opolon, P.12
Tilly, H.13
Solary, E.14
Duffourd, Y.15
Dessen, P.16
Merle-Beral, H.17
Nguyen-Khac, F.18
Fontenay, M.19
Vainchenker, W.20
Bastard, C.21
Mercher, T.22
Bernard, O.A.23
more..
-
80
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases
-
Xu W., Yang H., Liu Y., Yang Y., Wang P., Kim S.H., Ito S., Yang C., Xiao M.T., Liu L.X., Jiang W.Q., Liu J., Zhang J.Y., Wang B., Frye S., Zhang Y., Xu Y.H., Lei Q.Y., Guan K.L., Zhao S.M., Xiong Y. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases. Cancer Cell 2011, 19:17-30.
-
(2011)
Cancer Cell
, vol.19
, pp. 17-30
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
Yang, Y.4
Wang, P.5
Kim, S.H.6
Ito, S.7
Yang, C.8
Xiao, M.T.9
Liu, L.X.10
Jiang, W.Q.11
Liu, J.12
Zhang, J.Y.13
Wang, B.14
Frye, S.15
Zhang, Y.16
Xu, Y.H.17
Lei, Q.Y.18
Guan, K.L.19
Zhao, S.M.20
Xiong, Y.21
more..
-
81
-
-
79955948324
-
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells
-
Xu Y., Wu F., Tan L., Kong L., Xiong L., Deng J., Barbera A.J., Zheng L., Zhang H., Huang S., Min J., Nicholson T., Chen T., Xu G., Shi Y., Zhang K., Shi Y.G. Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol. Cell 2011, 42:451-464.
-
(2011)
Mol. Cell
, vol.42
, pp. 451-464
-
-
Xu, Y.1
Wu, F.2
Tan, L.3
Kong, L.4
Xiong, L.5
Deng, J.6
Barbera, A.J.7
Zheng, L.8
Zhang, H.9
Huang, S.10
Min, J.11
Nicholson, T.12
Chen, T.13
Xu, G.14
Shi, Y.15
Zhang, K.16
Shi, Y.G.17
-
82
-
-
79551587102
-
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
-
Koh K.P., Yabuuchi A., Rao S., Huang Y., Cunniff K., Nardone J., Laiho A., Tahiliani M., Sommer C.A., Mostoslavsky G., Lahesmaa R., Orkin S.H., Rodig S.J., Daley G.Q., Rao A. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 2011, 8:200-213.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 200-213
-
-
Koh, K.P.1
Yabuuchi, A.2
Rao, S.3
Huang, Y.4
Cunniff, K.5
Nardone, J.6
Laiho, A.7
Tahiliani, M.8
Sommer, C.A.9
Mostoslavsky, G.10
Lahesmaa, R.11
Orkin, S.H.12
Rodig, S.J.13
Daley, G.Q.14
Rao, A.15
-
83
-
-
79954457998
-
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
-
Wu H., D'Alessio A.C., Ito S., Wang Z., Cui K., Zhao K., Sun Y.E., Zhang Y. Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev. 2011, 25:679-684.
-
(2011)
Genes Dev.
, vol.25
, pp. 679-684
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Wang, Z.4
Cui, K.5
Zhao, K.6
Sun, Y.E.7
Zhang, Y.8
-
84
-
-
79961139741
-
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development
-
Dawlaty M.M., Ganz K., Powell B.E., Hu Y.C., Markoulaki S., Cheng A.W., Gao Q., Kim J., Choi S.W., Page D.C., Jaenisch R. Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell 2011, 9:166-175.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 166-175
-
-
Dawlaty, M.M.1
Ganz, K.2
Powell, B.E.3
Hu, Y.C.4
Markoulaki, S.5
Cheng, A.W.6
Gao, Q.7
Kim, J.8
Choi, S.W.9
Page, D.C.10
Jaenisch, R.11
-
85
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He Y.F., Li B.Z., Li Z., Liu P., Wang Y., Tang Q., Ding J., Jia Y., Chen Z., Li L., Sun Y., Li X., Dai Q., Song C.X., Zhang K., He C., Xu G.L. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 2011, 333:1303-1307.
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
Tang, Q.6
Ding, J.7
Jia, Y.8
Chen, Z.9
Li, L.10
Sun, Y.11
Li, X.12
Dai, Q.13
Song, C.X.14
Zhang, K.15
He, C.16
Xu, G.L.17
-
86
-
-
83855163995
-
Uncovering the role of 5-hydroxymethylcytosine in the epigenome
-
Branco M.R., Ficz G., Reik W. Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat. Rev. Genet. 2012, 13:7-13.
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 7-13
-
-
Branco, M.R.1
Ficz, G.2
Reik, W.3
-
87
-
-
77956095231
-
Active DNA demethylation: many roads lead to Rome
-
Wu S.C., Zhang Y. Active DNA demethylation: many roads lead to Rome. Nat. Rev. Mol. Cell Biol. 2010, 11:607-620.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 607-620
-
-
Wu, S.C.1
Zhang, Y.2
-
88
-
-
79960249232
-
Genomic mapping of 5-hydroxymethylcytosine in the human brain
-
Jin S.G., Wu X., Li A.X., Pfeifer G.P. Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Res. 2011, 39:5015-5024.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 5015-5024
-
-
Jin, S.G.1
Wu, X.2
Li, A.X.3
Pfeifer, G.P.4
-
89
-
-
78751595020
-
Polycomb preferentially targets stalled promoters of coding and noncoding transcripts
-
Enderle D., Beisel C., Stadler M.B., Gerstung M., Athri P., Paro R. Polycomb preferentially targets stalled promoters of coding and noncoding transcripts. Genome Res. 2011, 21:216-226.
-
(2011)
Genome Res.
, vol.21
, pp. 216-226
-
-
Enderle, D.1
Beisel, C.2
Stadler, M.B.3
Gerstung, M.4
Athri, P.5
Paro, R.6
-
90
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
-
Gu T.P., Guo F., Yang H., Wu H.P., Xu G.F., Liu W., Xie Z.G., Shi L., He X., Jin S.G., Iqbal K., Shi Y.G., Deng Z., Szabo P.E., Pfeifer G.P., Li J., Xu G.L. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 2011, 477:606-610.
-
(2011)
Nature
, vol.477
, pp. 606-610
-
-
Gu, T.P.1
Guo, F.2
Yang, H.3
Wu, H.P.4
Xu, G.F.5
Liu, W.6
Xie, Z.G.7
Shi, L.8
He, X.9
Jin, S.G.10
Iqbal, K.11
Shi, Y.G.12
Deng, Z.13
Szabo, P.E.14
Pfeifer, G.P.15
Li, J.16
Xu, G.L.17
-
91
-
-
79952713567
-
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
-
Wossidlo M., Nakamura T., Lepikhov K., Marques C.J., Zakhartchenko V., Boiani M., Arand J., Nakano T., Reik W., Walter J. 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nat. Commun. 2011, 2:241.
-
(2011)
Nat. Commun.
, vol.2
, pp. 241
-
-
Wossidlo, M.1
Nakamura, T.2
Lepikhov, K.3
Marques, C.J.4
Zakhartchenko, V.5
Boiani, M.6
Arand, J.7
Nakano, T.8
Reik, W.9
Walter, J.10
-
92
-
-
80054097425
-
Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos
-
Inoue A., Zhang Y. Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science 2011, 334:194.
-
(2011)
Science
, vol.334
, pp. 194
-
-
Inoue, A.1
Zhang, Y.2
-
93
-
-
79952763586
-
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
-
Iqbal K., Jin S.G., Pfeifer G.P., Szabo P.E. Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:3642-3647.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 3642-3647
-
-
Iqbal, K.1
Jin, S.G.2
Pfeifer, G.P.3
Szabo, P.E.4
-
94
-
-
84455167621
-
Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
-
Yildirim O., Li R., Hung J.H., Chen P.B., Dong X., Ee L.S., Weng Z., Rando O.J., Fazzio T.G. Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells. Cell 2011, 147:1498-1510.
-
(2011)
Cell
, vol.147
, pp. 1498-1510
-
-
Yildirim, O.1
Li, R.2
Hung, J.H.3
Chen, P.B.4
Dong, X.5
Ee, L.S.6
Weng, Z.7
Rando, O.J.8
Fazzio, T.G.9
-
95
-
-
78649281582
-
Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis
-
Conerly M.L., Teves S.S., Diolaiti D., Ulrich M., Eisenman R.N., Henikoff S. Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis. Genome Res. 2010, 20:1383-1390.
-
(2010)
Genome Res.
, vol.20
, pp. 1383-1390
-
-
Conerly, M.L.1
Teves, S.S.2
Diolaiti, D.3
Ulrich, M.4
Eisenman, R.N.5
Henikoff, S.6
-
96
-
-
59149084538
-
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
-
Irizarry R.A., Ladd-Acosta C., Wen B., Wu Z., Montano C., Onyango P., Cui H., Gabo K., Rongione M., Webster M., Ji H., Potash J.B., Sabunciyan S., Feinberg A.P. The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat. Genet. 2009, 41:178-186.
-
(2009)
Nat. Genet.
, vol.41
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
Wu, Z.4
Montano, C.5
Onyango, P.6
Cui, H.7
Gabo, K.8
Rongione, M.9
Webster, M.10
Ji, H.11
Potash, J.B.12
Sabunciyan, S.13
Feinberg, A.P.14
-
97
-
-
79960927422
-
Increased methylation variation in epigenetic domains across cancer types
-
Hansen K.D., Timp W., Bravo H.C., Sabunciyan S., Langmead B., McDonald O.G., Wen B., Wu H., Liu Y., Diep D., Briem E., Zhang K., Irizarry R.A., Feinberg A.P. Increased methylation variation in epigenetic domains across cancer types. Nat. Genet. 2011, 43:768-775.
-
(2011)
Nat. Genet.
, vol.43
, pp. 768-775
-
-
Hansen, K.D.1
Timp, W.2
Bravo, H.C.3
Sabunciyan, S.4
Langmead, B.5
McDonald, O.G.6
Wen, B.7
Wu, H.8
Liu, Y.9
Diep, D.10
Briem, E.11
Zhang, K.12
Irizarry, R.A.13
Feinberg, A.P.14
-
98
-
-
79959911384
-
Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer
-
Kim J.H., Dhanasekaran S.M., Prensner J.R., Cao X., Robinson D., Kalyana-Sundaram S., Huang C., Shankar S., Jing X., Iyer M., Hu M., Sam L., Grasso C., Maher C.A., Palanisamy N., Mehra R., Kominsky H.D., Siddiqui J., Yu J., Qin Z.S., Chinnaiyan A.M. Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer. Genome Res. 2011, 21:1028-1041.
-
(2011)
Genome Res.
, vol.21
, pp. 1028-1041
-
-
Kim, J.H.1
Dhanasekaran, S.M.2
Prensner, J.R.3
Cao, X.4
Robinson, D.5
Kalyana-Sundaram, S.6
Huang, C.7
Shankar, S.8
Jing, X.9
Iyer, M.10
Hu, M.11
Sam, L.12
Grasso, C.13
Maher, C.A.14
Palanisamy, N.15
Mehra, R.16
Kominsky, H.D.17
Siddiqui, J.18
Yu, J.19
Qin, Z.S.20
Chinnaiyan, A.M.21
more..
-
99
-
-
84856528270
-
Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer
-
Hon G.C., Hawkins R.D., Caballero O.L., Lo C., Lister R., Pelizzola M., Valsesia A., Ye Z., Kuan S., Edsall L.E., Camargo A.A., Stevenson B.J., Ecker J.R., Bafna V., Strausberg R.L., Simpson A.J., Ren B. Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer. Genome Res. 2012, 22:246-258.
-
(2012)
Genome Res.
, vol.22
, pp. 246-258
-
-
Hon, G.C.1
Hawkins, R.D.2
Caballero, O.L.3
Lo, C.4
Lister, R.5
Pelizzola, M.6
Valsesia, A.7
Ye, Z.8
Kuan, S.9
Edsall, L.E.10
Camargo, A.A.11
Stevenson, B.J.12
Ecker, J.R.13
Bafna, V.14
Strausberg, R.L.15
Simpson, A.J.16
Ren, B.17
-
100
-
-
84655162785
-
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains
-
Berman B.P., Weisenberger D.J., Aman J.F., Hinoue T., Ramjan Z., Liu Y., Noushmehr H., Lange C.P., van Dijk C.M., Tollenaar R.A., Van Den Berg D., Laird P.W. Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains. Nat. Genet. 2012, 44:40-46.
-
(2012)
Nat. Genet.
, vol.44
, pp. 40-46
-
-
Berman, B.P.1
Weisenberger, D.J.2
Aman, J.F.3
Hinoue, T.4
Ramjan, Z.5
Liu, Y.6
Noushmehr, H.7
Lange, C.P.8
van Dijk, C.M.9
Tollenaar, R.A.10
Van Den Berg, D.11
Laird, P.W.12
-
101
-
-
79955510962
-
Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer
-
Steine E.J., Ehrich M., Bell G.W., Raj A., Reddy S., van Oudenaarden A., Jaenisch R., Linhart H.G. Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer. J. Clin. Invest. 2011, 121:1748-1752.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1748-1752
-
-
Steine, E.J.1
Ehrich, M.2
Bell, G.W.3
Raj, A.4
Reddy, S.5
van Oudenaarden, A.6
Jaenisch, R.7
Linhart, H.G.8
-
102
-
-
66649097032
-
DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer
-
Nosho K., Shima K., Irahara N., Kure S., Baba Y., Kirkner G.J., Chen L., Gokhale S., Hazra A., Spiegelman D., Giovannucci E.L., Jaenisch R., Fuchs C.S., Ogino S. DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer. Clin. Cancer Res. 2009, 15:3663-3671.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 3663-3671
-
-
Nosho, K.1
Shima, K.2
Irahara, N.3
Kure, S.4
Baba, Y.5
Kirkner, G.J.6
Chen, L.7
Gokhale, S.8
Hazra, A.9
Spiegelman, D.10
Giovannucci, E.L.11
Jaenisch, R.12
Fuchs, C.S.13
Ogino, S.14
-
103
-
-
36849004469
-
Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing
-
Linhart H.G., Lin H., Yamada Y., Moran E., Steine E.J., Gokhale S., Lo G., Cantu E., Ehrich M., He T., Meissner A., Jaenisch R. Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. Genes Dev. 2007, 21:3110-3122.
-
(2007)
Genes Dev.
, vol.21
, pp. 3110-3122
-
-
Linhart, H.G.1
Lin, H.2
Yamada, Y.3
Moran, E.4
Steine, E.J.5
Gokhale, S.6
Lo, G.7
Cantu, E.8
Ehrich, M.9
He, T.10
Meissner, A.11
Jaenisch, R.12
-
104
-
-
78649906060
-
DNMT3A mutations in acute myeloid leukemia
-
Ley T.J., Ding L., Walter M.J., McLellan M.D., Lamprecht T., Larson D.E., Kandoth C., Payton J.E., Baty J., Welch J., Harris C.C., Lichti C.F., Townsend R.R., Fulton R.S., Dooling D.J., Koboldt D.C., Schmidt H., Zhang Q., Osborne J.R., Lin L., O'Laughlin M., McMichael J.F., Delehaunty K.D., McGrath S.D., Fulton L.A., Magrini V.J., Vickery T.L., Hundal J., Cook L.L., Conyers J.J., Swift G.W., Reed J.P., Alldredge P.A., Wylie T., Walker J., Kalicki J., Watson M.A., Heath S., Shannon W.D., Varghese N., Nagarajan R., Westervelt P., Tomasson M.H., Link D.C., Graubert T.A., DiPersio J.F., Mardis E.R., Wilson R.K. DNMT3A mutations in acute myeloid leukemia. N. Engl. J. Med. 2010, 363:2424-2433.
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 2424-2433
-
-
Ley, T.J.1
Ding, L.2
Walter, M.J.3
McLellan, M.D.4
Lamprecht, T.5
Larson, D.E.6
Kandoth, C.7
Payton, J.E.8
Baty, J.9
Welch, J.10
Harris, C.C.11
Lichti, C.F.12
Townsend, R.R.13
Fulton, R.S.14
Dooling, D.J.15
Koboldt, D.C.16
Schmidt, H.17
Zhang, Q.18
Osborne, J.R.19
Lin, L.20
O'Laughlin, M.21
McMichael, J.F.22
Delehaunty, K.D.23
McGrath, S.D.24
Fulton, L.A.25
Magrini, V.J.26
Vickery, T.L.27
Hundal, J.28
Cook, L.L.29
Conyers, J.J.30
Swift, G.W.31
Reed, J.P.32
Alldredge, P.A.33
Wylie, T.34
Walker, J.35
Kalicki, J.36
Watson, M.A.37
Heath, S.38
Shannon, W.D.39
Varghese, N.40
Nagarajan, R.41
Westervelt, P.42
Tomasson, M.H.43
Link, D.C.44
Graubert, T.A.45
DiPersio, J.F.46
Mardis, E.R.47
Wilson, R.K.48
more..
-
105
-
-
79953176952
-
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
-
Yan X.J., Xu J., Gu Z.H., Pan C.M., Lu G., Shen Y., Shi J.Y., Zhu Y.M., Tang L., Zhang X.W., Liang W.X., Mi J.Q., Song H.D., Li K.Q., Chen Z., Chen S.J. Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat. Genet. 2011, 43:309-315.
-
(2011)
Nat. Genet.
, vol.43
, pp. 309-315
-
-
Yan, X.J.1
Xu, J.2
Gu, Z.H.3
Pan, C.M.4
Lu, G.5
Shen, Y.6
Shi, J.Y.7
Zhu, Y.M.8
Tang, L.9
Zhang, X.W.10
Liang, W.X.11
Mi, J.Q.12
Song, H.D.13
Li, K.Q.14
Chen, Z.15
Chen, S.J.16
-
106
-
-
79960255863
-
Recurrent DNMT3A mutations in patients with myelodysplastic syndromes
-
Walter M.J., Ding L., Shen D., Shao J., Grillot M., McLellan M., Fulton R., Schmidt H., Kalicki-Veizer J., O'Laughlin M., Kandoth C., Baty J., Westervelt P., DiPersio J.F., Mardis E.R., Wilson R.K., Ley T.J., Graubert T.A. Recurrent DNMT3A mutations in patients with myelodysplastic syndromes. Leukemia 2011, 25:1153-1158.
-
(2011)
Leukemia
, vol.25
, pp. 1153-1158
-
-
Walter, M.J.1
Ding, L.2
Shen, D.3
Shao, J.4
Grillot, M.5
McLellan, M.6
Fulton, R.7
Schmidt, H.8
Kalicki-Veizer, J.9
O'Laughlin, M.10
Kandoth, C.11
Baty, J.12
Westervelt, P.13
DiPersio, J.F.14
Mardis, E.R.15
Wilson, R.K.16
Ley, T.J.17
Graubert, T.A.18
-
107
-
-
84863393263
-
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
-
Patel J.P., Gonen M., Figueroa M.E., Fernandez H., Sun Z., Racevskis J., Van Vlierberghe P., Dolgalev I., Thomas S., Aminova O., Huberman K., Cheng J., Viale A., Socci N.D., Heguy A., Cherry A., Vance G., Higgins R.R., Ketterling R.P., Gallagher R.E., Litzow M., van den Brink M.R., Lazarus H.M., Rowe J.M., Luger S., Ferrando A., Paietta E., Tallman M.S., Melnick A., Abdel-Wahab O., Levine R.L. Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. N. Engl. J. Med. 2012, 366:1079-1089.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 1079-1089
-
-
Patel, J.P.1
Gonen, M.2
Figueroa, M.E.3
Fernandez, H.4
Sun, Z.5
Racevskis, J.6
Van Vlierberghe, P.7
Dolgalev, I.8
Thomas, S.9
Aminova, O.10
Huberman, K.11
Cheng, J.12
Viale, A.13
Socci, N.D.14
Heguy, A.15
Cherry, A.16
Vance, G.17
Higgins, R.R.18
Ketterling, R.P.19
Gallagher, R.E.20
Litzow, M.21
van den Brink, M.R.22
Lazarus, H.M.23
Rowe, J.M.24
Luger, S.25
Ferrando, A.26
Paietta, E.27
Tallman, M.S.28
Melnick, A.29
Abdel-Wahab, O.30
Levine, R.L.31
more..
-
108
-
-
84855433323
-
Loss of Dnmt3b function upregulates the tumor modifier ment and accelerates mouse lymphomagenesis
-
Hlady R.A., Novakova S., Opavska J., Klinkebiel D., Peters S.L., Bies J., Hannah J., Iqbal J., Anderson K.M., Siebler H.M., Smith L.M., Greiner T.C., Bastola D., Joshi S., Lockridge O., Simpson M.A., Felsher D.W., Wagner K.U., Chan W.C., Christman J.K., Opavsky R. Loss of Dnmt3b function upregulates the tumor modifier ment and accelerates mouse lymphomagenesis. J. Clin. Invest. 2012, 122:163-177.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 163-177
-
-
Hlady, R.A.1
Novakova, S.2
Opavska, J.3
Klinkebiel, D.4
Peters, S.L.5
Bies, J.6
Hannah, J.7
Iqbal, J.8
Anderson, K.M.9
Siebler, H.M.10
Smith, L.M.11
Greiner, T.C.12
Bastola, D.13
Joshi, S.14
Lockridge, O.15
Simpson, M.A.16
Felsher, D.W.17
Wagner, K.U.18
Chan, W.C.19
Christman, J.K.20
Opavsky, R.21
more..
-
109
-
-
77949374305
-
Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation
-
Tao Y., Xi S., Briones V., Muegge K. Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation. PLoS One 2010, 5:e9163.
-
(2010)
PLoS One
, vol.5
-
-
Tao, Y.1
Xi, S.2
Briones, V.3
Muegge, K.4
-
110
-
-
83755185498
-
Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS
-
Tao Y., Liu S., Briones V., Geiman T.M., Muegge K. Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS. Nucleic Acids Res. 2011, 39:9508-9520.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 9508-9520
-
-
Tao, Y.1
Liu, S.2
Briones, V.3
Geiman, T.M.4
Muegge, K.5
-
111
-
-
66249137734
-
Mutation in TET2 in myeloid cancers
-
Delhommeau F., Dupont S., Della Valle V., James C., Trannoy S., Masse A., Kosmider O., Le Couedic J.P., Robert F., Alberdi A., Lecluse Y., Plo I., Dreyfus F.J., Marzac C., Casadevall N., Lacombe C., Romana S.P., Dessen P., Soulier J., Viguie F., Fontenay M., Vainchenker W., Bernard O.A. Mutation in TET2 in myeloid cancers. N. Engl. J. Med. 2009, 360:2289-2301.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 2289-2301
-
-
Delhommeau, F.1
Dupont, S.2
Della Valle, V.3
James, C.4
Trannoy, S.5
Masse, A.6
Kosmider, O.7
Le Couedic, J.P.8
Robert, F.9
Alberdi, A.10
Lecluse, Y.11
Plo, I.12
Dreyfus, F.J.13
Marzac, C.14
Casadevall, N.15
Lacombe, C.16
Romana, S.P.17
Dessen, P.18
Soulier, J.19
Viguie, F.20
Fontenay, M.21
Vainchenker, W.22
Bernard, O.A.23
more..
-
112
-
-
67649876132
-
Acquired mutations in TET2 are common in myelodysplastic syndromes
-
Langemeijer S.M., Kuiper R.P., Berends M., Knops R., Aslanyan M.G., Massop M., Stevens-Linders E., van Hoogen P., van Kessel A.G., Raymakers R.A., Kamping E.J., Verhoef G.E., Verburgh E., Hagemeijer A., Vandenberghe P., de Witte T., van der Reijden B.A., Jansen J.H. Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat. Genet. 2009, 41:838-842.
-
(2009)
Nat. Genet.
, vol.41
, pp. 838-842
-
-
Langemeijer, S.M.1
Kuiper, R.P.2
Berends, M.3
Knops, R.4
Aslanyan, M.G.5
Massop, M.6
Stevens-Linders, E.7
van Hoogen, P.8
van Kessel, A.G.9
Raymakers, R.A.10
Kamping, E.J.11
Verhoef, G.E.12
Verburgh, E.13
Hagemeijer, A.14
Vandenberghe, P.15
de Witte, T.16
van der Reijden, B.A.17
Jansen, J.H.18
-
113
-
-
84866419591
-
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma
-
Lian C.G., Xu Y., Ceol C., Wu F., Larson A., Dresser K., Xu W., Tan L., Hu Y., Zhan Q., Lee C.W., Hu D., Lian B.Q., Kleffel S., Yang Y., Neiswender J., Khorasani A.J., Fang R., Lezcano C., Duncan L.M., Scolyer R.A., Thompson J.F., Kakavand H., Houvras Y., Zon L.I., Mihm M.C., Kaiser U.B., Schatton T., Woda B.A., Murphy G.F., Shi Y.G. Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell 2012, 150:1135-1146.
-
(2012)
Cell
, vol.150
, pp. 1135-1146
-
-
Lian, C.G.1
Xu, Y.2
Ceol, C.3
Wu, F.4
Larson, A.5
Dresser, K.6
Xu, W.7
Tan, L.8
Hu, Y.9
Zhan, Q.10
Lee, C.W.11
Hu, D.12
Lian, B.Q.13
Kleffel, S.14
Yang, Y.15
Neiswender, J.16
Khorasani, A.J.17
Fang, R.18
Lezcano, C.19
Duncan, L.M.20
Scolyer, R.A.21
Thompson, J.F.22
Kakavand, H.23
Houvras, Y.24
Zon, L.I.25
Mihm, M.C.26
Kaiser, U.B.27
Schatton, T.28
Woda, B.A.29
Murphy, G.F.30
Shi, Y.G.31
more..
-
114
-
-
79960064353
-
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
Moran-Crusio K., Reavie L., Shih A., Abdel-Wahab O., Ndiaye-Lobry D., Lobry C., Figueroa M.E., Vasanthakumar A., Patel J., Zhao X., Perna F., Pandey S., Madzo J., Song C., Dai Q., He C., Ibrahim S., Beran M., Zavadil J., Nimer S.D., Melnick A., Godley L.A., Aifantis I., Levine R.L. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 2011, 20:11-24.
-
(2011)
Cancer Cell
, vol.20
, pp. 11-24
-
-
Moran-Crusio, K.1
Reavie, L.2
Shih, A.3
Abdel-Wahab, O.4
Ndiaye-Lobry, D.5
Lobry, C.6
Figueroa, M.E.7
Vasanthakumar, A.8
Patel, J.9
Zhao, X.10
Perna, F.11
Pandey, S.12
Madzo, J.13
Song, C.14
Dai, Q.15
He, C.16
Ibrahim, S.17
Beran, M.18
Zavadil, J.19
Nimer, S.D.20
Melnick, A.21
Godley, L.A.22
Aifantis, I.23
Levine, R.L.24
more..
-
115
-
-
84863621527
-
Cancer epigenetics: from mechanism to therapy
-
Dawson M.A., Kouzarides T. Cancer epigenetics: from mechanism to therapy. Cell 2012, 150:12-27.
-
(2012)
Cell
, vol.150
, pp. 12-27
-
-
Dawson, M.A.1
Kouzarides, T.2
-
116
-
-
85027954125
-
DNA methylation profiling in the clinic: applications and challenges
-
Heyn H., Esteller M. DNA methylation profiling in the clinic: applications and challenges. Nat. Rev. Genet. 2012, 13:679-692.
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 679-692
-
-
Heyn, H.1
Esteller, M.2
-
117
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Bernstein B.E., Birney E., Dunham I., Green E.D., Gunter C., Snyder M. An integrated encyclopedia of DNA elements in the human genome. Nature 2012, 489:57-74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Bernstein, B.E.1
Birney, E.2
Dunham, I.3
Green, E.D.4
Gunter, C.5
Snyder, M.6
-
118
-
-
77249178763
-
DNA methylation increases nucleosome compaction and rigidity
-
Choy J.S., Wei S., Lee J.Y., Tan S., Chu S., Lee T.H. DNA methylation increases nucleosome compaction and rigidity. J. Am. Chem. Soc. 2010, 132:1782-1783.
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 1782-1783
-
-
Choy, J.S.1
Wei, S.2
Lee, J.Y.3
Tan, S.4
Chu, S.5
Lee, T.H.6
-
119
-
-
70349873824
-
Comprehensive mapping of long-range interactions reveals folding principles of the human genome
-
Lieberman-Aiden E., van Berkum N.L., Williams L., Imakaev M., Ragoczy T., Telling A., Amit I., Lajoie B.R., Sabo P.J., Dorschner M.O., Sandstrom R., Bernstein B., Bender M.A., Groudine M., Gnirke A., Stamatoyannopoulos J., Mirny L.A., Lander E.S., Dekker J. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 2009, 326:289-293.
-
(2009)
Science
, vol.326
, pp. 289-293
-
-
Lieberman-Aiden, E.1
van Berkum, N.L.2
Williams, L.3
Imakaev, M.4
Ragoczy, T.5
Telling, A.6
Amit, I.7
Lajoie, B.R.8
Sabo, P.J.9
Dorschner, M.O.10
Sandstrom, R.11
Bernstein, B.12
Bender, M.A.13
Groudine, M.14
Gnirke, A.15
Stamatoyannopoulos, J.16
Mirny, L.A.17
Lander, E.S.18
Dekker, J.19
-
120
-
-
84861221693
-
Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution
-
Booth M.J., Branco M.R., Ficz G., Oxley D., Krueger F., Reik W., Balasubramanian S. Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science 2012, 336:934-937.
-
(2012)
Science
, vol.336
, pp. 934-937
-
-
Booth, M.J.1
Branco, M.R.2
Ficz, G.3
Oxley, D.4
Krueger, F.5
Reik, W.6
Balasubramanian, S.7
-
121
-
-
84861990517
-
Base-resolution analysis of 5-hydroxymethylcytosine in the Mammalian genome
-
Yu M., Hon G.C., Szulwach K.E., Song C.X., Zhang L., Kim A., Li X., Dai Q., Shen Y., Park B., Min J.H., Jin P., Ren B., He C. Base-resolution analysis of 5-hydroxymethylcytosine in the Mammalian genome. Cell 2012, 149:1368-1380.
-
(2012)
Cell
, vol.149
, pp. 1368-1380
-
-
Yu, M.1
Hon, G.C.2
Szulwach, K.E.3
Song, C.X.4
Zhang, L.5
Kim, A.6
Li, X.7
Dai, Q.8
Shen, Y.9
Park, B.10
Min, J.H.11
Jin, P.12
Ren, B.13
He, C.14
|