Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS

Nucleic Acids Research

Volumn 39, Issue 22, 2011, Pages 9508-9520

  Tao, Yongguang ^a,b   Liu, Shuang ^c   Briones, Victorino ^a   Geiman, Theresa M ^a   Muegge, Kathrin ^a  

^a SAIC FREDERICK INC   (United States)

^b Central South University   (China)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZACITIDINE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA METHYLTRANSFERASE 3B; EPIGALLOCATECHIN GALLATE; PARTHENOLIDE; PROTEIN LSH; QUERCETIN; REGULATOR PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; DRUG MECHANISM; ENZYME BINDING; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; RNA INTERFERENCE; RNA TRANSLATION; TRANSCRIPTION INITIATION SITE; UPREGULATION;

AZACITIDINE; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA HELICASES; DNA METHYLATION; DNA-BINDING PROTEINS; FEMALE; GENE SILENCING; HISTONES; HUMANS; REPRESSOR PROTEINS; RNA POLYMERASE II; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

EID: 83755185498     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr611     Document Type: Article

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