Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 44, 2011, Pages 18061-18066

  Gao, Qing ^a   Steine, Eveline J ^a   Barrasa, M Inmaculada ^a   Hockemeyer, Dirk ^a   Pawlak, Mathias ^a   Fu, Dongdong ^a   Reddy, Seshamma ^a,c   Bell, George W ^a   Jaenisch, Rudolf ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c OralCDx Laboratories   (United States)

Author keywords

Adenocarcinoma; Cancer epigenetics; Gene body methylation; K ras

Indexed keywords

DNA; DNA METHYLTRANSFERASE 3A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL MOTION; CELL PROLIFERATION; CONTROLLED STUDY; DNA METHYLATION; GENE DELETION; GENE EXPRESSION; LIFESPAN; LUNG TUMOR; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE K RAS; PRIORITY JOURNAL; TUMOR CELL; TUMOR GROWTH; TUMOR MODEL; TUMOR SUPPRESSOR GENE;

ANIMALS; BASE SEQUENCE; CELL DIVISION; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA PRIMERS; GENE SILENCING; LUNG NEOPLASMS; MICE; MICE, KNOCKOUT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 81055130253     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1114946108     Document Type: Article

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