Apigenin attenuates copper-mediated β-amyloid neurotoxicity through antioxidation, mitochondrion protection and MAPK signal inactivation in an AD cell model

Brain Research

Volumn 1492, Issue , 2013, Pages 33-45

  Zhao, Le ^a   Wang, Jun Li ^a   Wang, Yan Rui ^b   Fa, Xiu Zhi ^b  

^a MINZU UNIVERSITY OF CHINA   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Amyloid peptide; Apigenin; Apoptosis; Mitochondrion

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; ANTIOXIDANT; APIGENIN; COPPER; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CHEMICAL REACTION; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NEUROPROTECTION; NEUROTOXICITY; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; APIGENIN; APOPTOSIS; CELL LINE, TUMOR; COPPER; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIA; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATION-REDUCTION;

EID: 84871919725     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.11.019     Document Type: Article

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