Endothelium-dependent vasorelaxant and antiproliferative effects of apigenin

General Pharmacology: Vascular System

Volumn 35, Issue 6, 2000, Pages 341-347

  Zhang, Yong He ^a   Park, Yang Su ^b   Kim, Tack Joong ^b   Fang, Lian Hua ^a   Ahn, Hee Yul ^b,c   Hong, JinTae ^b   Kim, Youngsoo ^b   Lee, Chong Kil ^b   Yun, Yeo Pyo ^b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b Chungbuk National University   (South Korea)

^c Chungbuk National University College of Medicine   (South Korea)

Author keywords

Apigenin; cGMP; Nitric oxide; Proliferation; Rat aorta; Vasorelaxation

Indexed keywords

ACETYLCHOLINE; APIGENIN; CALCIUM ION; CYCLIC GMP; DNA; METHYLENE BLUE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHENYLEPHRINE; PHORBOL DIBUTYRATE; PROTEIN KINASE C; THYMIDINE; TRITIUM; FLAVONOID;

ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTERY CONSTRICTION; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; CALCIUM TRANSPORT; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG DNA BINDING; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; ENZYME ACTIVITY; INHIBITION KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR RING; ANIMAL; CELL CULTURE; CELL DIVISION; CYTOLOGY; METABOLISM; MUSCLE ISOMETRIC CONTRACTION; MUSCLE RELAXATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT; THORACIC AORTA; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA, THORACIC; APIGENIN; CELL DIVISION; CELLS, CULTURED; CYCLIC GMP; ENDOTHELIUM, VASCULAR; FLAVONOIDS; ISOMETRIC CONTRACTION; MALE; METHYLENE BLUE; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; NG-NITROARGININE METHYL ESTER; PHORBOL 12,13-DIBUTYRATE; RATS; RATS, SPRAGUE-DAWLEY; THYMIDINE;

EID: 0034581924     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(02)00113-1     Document Type: Article

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