Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis

BMC Medicine

Volumn 10, Issue , 2012, Pages

  Liu, Rui ^a   Wu, Cai Xia ^a,b   Zhou, Dan ^a   Yang, Fan ^a   Tian, Shuo ^a   Zhang, Li ^a   Zhang, Tian Tai ^a   Du, Guan Hua ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Amyloid peptide; Apoptosis; Pinocembrin; Receptor for advanced glycation end products

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; AMYLOID BETA PROTEIN[25-35]; CASPASE 3; CASPASE 9; CYTOCHROME C; HEAT SHOCK PROTEIN 27; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PINOCEMBRINE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BEHAVIOR; BRAIN CORTEX; COGNITION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FLUORESCENCE; GENE OVEREXPRESSION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NERVE CELL DEGENERATION; NEUROPIL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; APOPTOSIS; CEREBRAL CORTEX; COGNITION; DISEASE MODELS, ANIMAL; FLAVANONES; GENE EXPRESSION PROFILING; MALE; MICE; MITOCHONDRIA; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION;

EID: 84866305795     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-10-105     Document Type: Article

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