메뉴 건너뛰기




Volumn 28, Issue 8, 2009, Pages 1131-1141

Differential regulation of homologous recombination at DNA breaks and replication forks by the Mrc1 branch of the S-phase checkpoint

Author keywords

Checkpoints; DNA replication; Genomic instability; Homologous recombination; S. cerevisiae

Indexed keywords

ENDONUCLEASE; MEC1 PROTEIN; MRC1 PROTEIN; PROTEIN; RAD52 PROTEIN; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

EID: 67349097341     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2009.75     Document Type: Article
Times cited : (79)

References (71)
  • 3
    • 11244269445 scopus 로고    scopus 로고
    • The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
    • Aylon Y, Liefshitz B, Kupiec M (2004) The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle. EMBO J 23: 4868-4875
    • (2004) EMBO J , vol.23 , pp. 4868-4875
    • Aylon, Y.1    Liefshitz, B.2    Kupiec, M.3
  • 6
    • 0032519615 scopus 로고    scopus 로고
    • The Cdc7 protein kinase is required for origin firing during S phase
    • Bousset K, Diffley JF (1998) The Cdc7 protein kinase is required for origin firing during S phase. Genes Dev 12: 480-490
    • (1998) Genes Dev , vol.12 , pp. 480-490
    • Bousset, K.1    Diffley, J.F.2
  • 7
    • 36849052400 scopus 로고    scopus 로고
    • RecQ helicases queuing with Srs2 to disrupt Rad51 filaments and suppress recombination
    • Branzei D, Foiani M (2007) RecQ helicases queuing with Srs2 to disrupt Rad51 filaments and suppress recombination. Genes Dev21: 3019-3026
    • (2007) Genes Dev , vol.21 , pp. 3019-3026
    • Branzei, D.1    Foiani, M.2
  • 8
    • 41149094512 scopus 로고    scopus 로고
    • Regulation of DNA repair throughout the cell cycle
    • Branzei D, Foiani M (2008) Regulation of DNA repair throughout the cell cycle. Nat Rev Mol Cell Biol 9: 297-308
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 297-308
    • Branzei, D.1    Foiani, M.2
  • 9
    • 33750437743 scopus 로고    scopus 로고
    • Ubc9- and Mms21 -mediated sumoylation counteracts recombinogenic events at damaged replication forks
    • Branzei D, Sollier J, Liberi G, Zhao X, Maeda D, Seki M, Enomoto T, Ohta K, Foiani M (2006) Ubc9- and Mms21 -mediated sumoylation counteracts recombinogenic events at damaged replication forks. Cell 127: 509-522
    • (2006) Cell , vol.127 , pp. 509-522
    • Branzei, D.1    Sollier, J.2    Liberi, G.3    Zhao, X.4    Maeda, D.5    Seki, M.6    Enomoto, T.7    Ohta, K.8    Foiani, M.9
  • 10
    • 0030479885 scopus 로고    scopus 로고
    • The ATM homo- logue MEC1 is required for phosphorylation of replication protein A in yeast
    • Brush GS, Morrow DM, Hieter P, Kelly TJ (1996) The ATM homo- logue MEC1 is required for phosphorylation of replication protein A in yeast. Proc Natl Acad Sci USA 93: 15075-15080
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15075-15080
    • Brush, G.S.1    Morrow, D.M.2    Hieter, P.3    Kelly, T.J.4
  • 11
    • 0037168646 scopus 로고    scopus 로고
    • A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage
    • Chang M, Bellaoui M, Boone C, Brown GW (2002) A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage. Proc Natl Acad Sci USA 99: 16934-16939
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16934-16939
    • Chang, M.1    Bellaoui, M.2    Boone, C.3    Brown, G.W.4
  • 12
    • 33644691699 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends
    • Clerici M, Mantiero D, Lucchini G, Longhese MP (2005) The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends. J Biol Chem 280:38631-38638
    • (2005) J Biol Chem , vol.280 , pp. 38631-38638
    • Clerici, M.1    Mantiero, D.2    Lucchini, G.3    Longhese, M.P.4
  • 13
    • 0042466524 scopus 로고    scopus 로고
    • DNA polymerase stabilization at stalled replication forks requires Mecl and the RecQ helicase Sgsl
    • Cobb JA, Bjergbaek L, Shimada K, Frei C, Gasser SM (2003) DNA polymerase stabilization at stalled replication forks requires Mecl and the RecQ helicase Sgsl. EMBO J 22: 4325-4336
    • (2003) EMBO J , vol.22 , pp. 4325-4336
    • Cobb, J.A.1    Bjergbaek, L.2    Shimada, K.3    Frei, C.4    Gasser, S.M.5
  • 14
    • 29144486147 scopus 로고    scopus 로고
    • Replisome instability, fork collapse, and gross chromoso- mal rearrangements arise synergistically from Mecl kinase and RecQ helicase mutations
    • Cobb JA, Schleker T, Rojas V, Bjergbaek L, Tercero JA, Gasser SM (2005) Replisome instability, fork collapse, and gross chromoso- mal rearrangements arise synergistically from Mecl kinase and RecQ helicase mutations. Genes Dev 19: 3055-3069
    • (2005) Genes Dev , vol.19 , pp. 3055-3069
    • Cobb, J.A.1    Schleker, T.2    Rojas, V.3    Bjergbaek, L.4    Tercero, J.A.5    Gasser, S.M.6
  • 15
    • 11344268431 scopus 로고    scopus 로고
    • Exol processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells
    • Cotta-Ramusino C, Fachinetti D, Lucca C, Doksani Y, Lopes M, Sogo J, Foiani M (2005) Exol processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells. Mol Cell17: 153-159
    • (2005) Mol Cell , vol.17 , pp. 153-159
    • Cotta-Ramusino, C.1    Fachinetti, D.2    Lucca, C.3    Doksani, Y.4    Lopes, M.5    Sogo, J.6    Foiani, M.7
  • 16
    • 40649097306 scopus 로고    scopus 로고
    • Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein A
    • Davies AA, Huttner D, Daigaku Y, Chen S, Ulrich HD (2008) Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein A. Mol Cell 29: 625-636
    • (2008) Mol Cell , vol.29 , pp. 625-636
    • Davies, A.A.1    Huttner, D.2    Daigaku, Y.3    Chen, S.4    Ulrich, H.D.5
  • 17
    • 42249099979 scopus 로고    scopus 로고
    • Budding yeast Mms22 and Mmsl regulate homologous recombination induced by replisome blockage
    • Duro E, Vaisica JA, Brown GW, Rouse J (2008) Budding yeast Mms22 and Mmsl regulate homologous recombination induced by replisome blockage. DNA Repair (Amst) 7: 811-818
    • (2008) DNA Repair (Amst) , vol.7 , pp. 811-818
    • Duro, E.1    Vaisica, J.A.2    Brown, G.W.3    Rouse, J.4
  • 18
    • 0037168658 scopus 로고    scopus 로고
    • Alternate pathways involving Sgsl/Top3, Mus81/Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication
    • Fabre F, Chan A, Heyer WD, Gangloff S (2002) Alternate pathways involving Sgsl/Top3, Mus81/Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication. Proc Natl Acad Sci USA 99:16887-16892
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16887-16892
    • Fabre, F.1    Chan, A.2    Heyer, W.D.3    Gangloff, S.4
  • 19
    • 0034922586 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae rad51 mutants are defective in DNA damage-associated sister chromatid exchanges but exhibit in- creased rates of homology-directed translocations
    • Fasullo M, Giallanza P, Dong Z, Cera C, Bennett T (2001) Saccharomyces cerevisiae rad51 mutants are defective in DNA damage-associated sister chromatid exchanges but exhibit in- creased rates of homology-directed translocations. Genetics 158:959-972
    • (2001) Genetics , vol.158 , pp. 959-972
    • Fasullo, M.1    Giallanza, P.2    Dong, Z.3    Cera, C.4    Bennett, T.5
  • 21
    • 0034119866 scopus 로고    scopus 로고
    • Homologous recombination is responsible for cell death in the absence of the Sgsl and Srs2 helicases
    • Gangloff S, Soustelle C, Fabre F (2000) Homologous recombination is responsible for cell death in the absence of the Sgsl and Srs2 helicases. Nat Genet 25: 192-194
    • (2000) Nat Genet , vol.25 , pp. 192-194
    • Gangloff, S.1    Soustelle, C.2    Fabre, F.3
  • 22
    • 37249025795 scopus 로고    scopus 로고
    • Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replica- tive stress
    • Ge XQ, Jackson DA, Blow JJ (2007) Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replica- tive stress. Genes Dev 21: 3331-3341
    • (2007) Genes Dev , vol.21 , pp. 3331-3341
    • Ge, X.Q.1    Jackson, D.A.2    Blow, J.J.3
  • 23
    • 0034881760 scopus 로고    scopus 로고
    • Budding yeast Rad9 is an ATP-dependent Rad53 activating machine
    • Gilbert CS, Green CM, Lowndes NF (2001) Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. Mol Cell 8: 129-136
    • (2001) Mol Cell , vol.8 , pp. 129-136
    • Gilbert, C.S.1    Green, C.M.2    Lowndes, N.F.3
  • 26
    • 48249084972 scopus 로고    scopus 로고
    • Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication
    • Ibarra A, Schwob E, Mendez J (2008) Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication. Proc Natl Acad Sci USA 105: 8956-8961
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 8956-8961
    • Ibarra, A.1    Schwob, E.2    Mendez, J.3
  • 28
    • 17444416489 scopus 로고    scopus 로고
    • Replication check- point kinase Cdsl regulates Mus81 to preserve genome integrity during replication stress
    • Kai M, Boddy MN, Russell P, Wang TS (2005) Replication check- point kinase Cdsl regulates Mus81 to preserve genome integrity during replication stress. Genes Dev 19: 919-932
    • (2005) Genes Dev , vol.19 , pp. 919-932
    • Kai, M.1    Boddy, M.N.2    Russell, P.3    Wang, T.S.4
  • 29
    • 0345791546 scopus 로고    scopus 로고
    • Hydroxyurea arrests DNA replication by a mechanism that preserves basal dNTP pools
    • Koc A, Wheeler LI, Mathews CK, Merrill GF (2004) Hydroxyurea arrests DNA replication by a mechanism that preserves basal dNTP pools. J Biol Chem 279: 223-230
    • (2004) J Biol Chem , vol.279 , pp. 223-230
    • Koc, A.1    Wheeler, L.I.2    Mathews, C.K.3    Merrill, G.F.4
  • 31
    • 10344263324 scopus 로고    scopus 로고
    • Recombination proteins in yeast
    • Krogh BO, Symington LS (2004) Recombination proteins in yeast. Annu Rev Genet 38: 233-271
    • (2004) Annu Rev Genet , vol.38 , pp. 233-271
    • Krogh, B.O.1    Symington, L.S.2
  • 32
    • 34047094441 scopus 로고    scopus 로고
    • Replication fork barriers: Pausing for a break or stalling for time?
    • Labib K, Hodgson B (2007) Replication fork barriers: pausing for a break or stalling for time? EMBO Rep 8: 346-353
    • (2007) EMBO Rep , vol.8 , pp. 346-353
    • Labib, K.1    Hodgson, B.2
  • 33
    • 4544281398 scopus 로고    scopus 로고
    • Choreography of the DNA damage response; spatiotemporal relationships among checkpoint and repair proteins
    • Lisby M, Barlow JH, Burgess RC, Rothstein R (2004) Choreography of the DNA damage response; spatiotemporal relationships among checkpoint and repair proteins. Cell 118: 699-713
    • (2004) Cell , vol.118 , pp. 699-713
    • Lisby, M.1    Barlow, J.H.2    Burgess, R.C.3    Rothstein, R.4
  • 34
    • 0035902544 scopus 로고    scopus 로고
    • Rad52 forms DNA repair and recombination centers during S phase
    • Lisby M, Rothstein R, Mortensen UH (2001) Rad52 forms DNA repair and recombination centers during S phase. Proc Natl Acad Sci USA 98: 8276-8282
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8276-8282
    • Lisby, M.1    Rothstein, R.2    Mortensen, U.H.3
  • 35
    • 42449130956 scopus 로고    scopus 로고
    • Break-induced replica- tion: What is it and what is it for?
    • Llorente B, Smith CE, Symington LS (2008) Break-induced replica- tion: what is it and what is it for? Cell Cycle 7: 859-864
    • (2008) Cell Cycle , vol.7 , pp. 859-864
    • Llorente, B.1    Smith, C.E.2    Symington, L.S.3
  • 36
    • 6344254299 scopus 로고    scopus 로고
    • The Mrell nuclease is not required for 5' to 3' resection at multiple HO-induced double-strand breaks
    • Llorente B, Symington LS (2004) The Mrell nuclease is not required for 5' to 3' resection at multiple HO-induced double-strand breaks. Mol Cell Biol 24: 9682-9694
    • (2004) Mol Cell Biol , vol.24 , pp. 9682-9694
    • Llorente, B.1    Symington, L.S.2
  • 38
    • 33646073448 scopus 로고    scopus 로고
    • The cullin Rtt101p promotes replication fork progression through damaged DNA and natural pause sites
    • Luke B, Versini G, Jaquenoud M, Zaidi IW, Kurz T, Pintard L, Pasero P, Peter M (2006) The cullin Rtt101p promotes replication fork progression through damaged DNA and natural pause sites. Curr Biol 16: 786-792
    • (2006) Curr Biol , vol.16 , pp. 786-792
    • Luke, B.1    Versini, G.2    Jaquenoud, M.3    Zaidi, I.W.4    Kurz, T.5    Pintard, L.6    Pasero, P.7    Peter, M.8
  • 39
    • 22244474639 scopus 로고    scopus 로고
    • Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double- strand breaks
    • Lundin C, North M, Erixon K, Walters K, Jenssen D, Goldman AS, Helleday T (2005) Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double- strand breaks. Nucleic Acids Res 33: 3799-3811
    • (2005) Nucleic Acids Res , vol.33 , pp. 3799-3811
    • Lundin, C.1    North, M.2    Erixon, K.3    Walters, K.4    Jenssen, D.5    Goldman, A.S.6    Helleday, T.7
  • 40
    • 13944261496 scopus 로고    scopus 로고
    • Temporal separation of replication and recombination requires the intra-S checkpoint
    • Meister P, Taddei A, Vernis L, Poidevin M, Gasser SM, Baldacci G (2005) Temporal separation of replication and recombination requires the intra-S checkpoint. J Cell Biol 168: 537-544
    • (2005) J Cell Biol , vol.168 , pp. 537-544
    • Meister, P.1    Taddei, A.2    Vernis, L.3    Poidevin, M.4    Gasser, S.M.5    Baldacci, G.6
  • 43
    • 53649104599 scopus 로고    scopus 로고
    • Sae2, Exol and Sgsl collaborate in DNA double-strand break processing
    • Mimitou EP, Symington LS (2008) Sae2, Exol and Sgsl collaborate in DNA double-strand break processing. Nature 455: 770-774
    • (2008) Nature , vol.455 , pp. 770-774
    • Mimitou, E.P.1    Symington, L.S.2
  • 44
    • 51949118680 scopus 로고    scopus 로고
    • Checkpoint-dependent phosphorylation of Exol modulates the DNA damage response
    • Morin I, Ngo HP, Greenall A, Zubko MK, Morrice N, Lydall D (2008) Checkpoint-dependent phosphorylation of Exol modulates the DNA damage response. EMBO J 27: 2400-2410
    • (2008) EMBO J , vol.27 , pp. 2400-2410
    • Morin, I.1    Ngo, H.P.2    Greenall, A.3    Zubko, M.K.4    Morrice, N.5    Lydall, D.6
  • 45
    • 0038506000 scopus 로고    scopus 로고
    • Mrcl is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53
    • Osborn AJ, Elledge SJ (2003) Mrcl is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53. Genes Dev 17: 1755-1767
    • (2003) Genes Dev , vol.17 , pp. 1755-1767
    • Osborn, A.J.1    Elledge, S.J.2
  • 46
    • 0038799991 scopus 로고    scopus 로고
    • Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae
    • Paques F, Haber JE (1999) Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev 63: 349-404
    • (1999) Microbiol Mol Biol Rev , vol.63 , pp. 349-404
    • Paques, F.1    Haber, J.E.2
  • 47
    • 0036791653 scopus 로고    scopus 로고
    • Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus
    • Pasero P, Bensimon A, Schwob E (2002) Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus. Genes Dev 16: 2479-2484
    • (2002) Genes Dev , vol.16 , pp. 2479-2484
    • Pasero, P.1    Bensimon, A.2    Schwob, E.3
  • 48
    • 0033570894 scopus 로고    scopus 로고
    • Activation of Rad53 kinase in response to DNA damage and its effect in modulating phospho- rylation of the lagging strand DNA polymerase
    • Pellicioli A, Lucca C, Liberi G, Marini F, Lopes M, Plevani P, Romano A, Di Fiore PP, Foiani M (1999) Activation of Rad53 kinase in response to DNA damage and its effect in modulating phospho- rylation of the lagging strand DNA polymerase. EMBO J 18:6561-6572
    • (1999) EMBO J , vol.18 , pp. 6561-6572
    • Pellicioli, A.1    Lucca, C.2    Liberi, G.3    Marini, F.4    Lopes, M.5    Plevani, P.6    Romano, A.7    Di Fiore, P.P.8    Foiani, M.9
  • 49
    • 22944474665 scopus 로고    scopus 로고
    • SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase
    • Pfander B, Moldovan G-L, Sacher M, Hoege C, Jentsch S (2005) SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase. Nature 436: 428-433
    • (2005) Nature , vol.436 , pp. 428-433
    • Pfander, B.1    Moldovan, G.-L.2    Sacher, M.3    Hoege, C.4    Jentsch, S.5
  • 50
    • 33749034730 scopus 로고    scopus 로고
    • Topoisomerase I inhibitors: Camptothecins and beyond
    • Pommier Y (2006) Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer 6: 789-802
    • (2006) Nat Rev Cancer , vol.6 , pp. 789-802
    • Pommier, Y.1
  • 52
    • 33748809503 scopus 로고    scopus 로고
    • SUMO-binding motifs mediate the Rad60-dependent response to replicative stress and self-association
    • Raffa GD, Wohlschlegel J, Yates III JR, Boddy MN (2006) SUMO-binding motifs mediate the Rad60-dependent response to replicative stress and self-association. J Biol Chem 281:27973-27981
    • (2006) J Biol Chem , vol.281 , pp. 27973-27981
    • Raffa, G.D.1    Wohlschlegel, J.2    Yates III, J.R.3    Boddy, M.N.4
  • 53
    • 55749093286 scopus 로고    scopus 로고
    • DNA double-strand break proces- sing: The beginning of the end
    • Raynard S, Niu H, Sung P (2008) DNA double-strand break proces- sing: the beginning of the end. Genes Dev 22: 2903-2907
    • (2008) Genes Dev , vol.22 , pp. 2903-2907
    • Raynard, S.1    Niu, H.2    Sung, P.3
  • 54
    • 0043066728 scopus 로고    scopus 로고
    • Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage
    • Redon C, Pilch DR, Rogakou EP, Orr AH, Lowndes NF, Bonner WM (2003) Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage. EMBO Rep 4: 678-684
    • (2003) EMBO Rep , vol.4 , pp. 678-684
    • Redon, C.1    Pilch, D.R.2    Rogakou, E.P.3    Orr, A.H.4    Lowndes, N.F.5    Bonner, W.M.6
  • 55
    • 0036241880 scopus 로고    scopus 로고
    • Lcd1p recruits Meclp to DNA lesions in vitro and in vivo
    • Rouse J, Jackson SP (2002) Lcd1p recruits Meclp to DNA lesions in vitro and in vivo. Mol Cell 9: 857-869
    • (2002) Mol Cell , vol.9 , pp. 857-869
    • Rouse, J.1    Jackson, S.P.2
  • 56
    • 50649100744 scopus 로고    scopus 로고
    • Mechanism of eukaryotic homologous recombination
    • San Filippo J, Sung P, Klein H (2008) Mechanism of eukaryotic homologous recombination. Annu Rev Biochem 77: 229-257
    • (2008) Annu Rev Biochem , vol.77 , pp. 229-257
    • San Filippo, J.1    Sung, P.2    Klein, H.3
  • 57
    • 46249122812 scopus 로고    scopus 로고
    • Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks
    • Segurado M, Diffley JFX (2008) Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks. Genes Dev 22: 1816-1827
    • (2008) Genes Dev , vol.22 , pp. 1816-1827
    • Segurado, M.1    Diffley, J.F.X.2
  • 58
    • 0037178740 scopus 로고    scopus 로고
    • Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
    • Sogo JM, Lopes M, Foiani M (2002) Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science 297: 599-602
    • (2002) Science , vol.297 , pp. 599-602
    • Sogo, J.M.1    Lopes, M.2    Foiani, M.3
  • 60
    • 33745208227 scopus 로고    scopus 로고
    • Repair of DNA double strand breaks: In vivo biochemistry
    • Sugawara N, Haber JE (2006) Repair of DNA double strand breaks: in vivo biochemistry. Methods Enzymol 408: 416-429
    • (2006) Methods Enzymol , vol.408 , pp. 416-429
    • Sugawara, N.1    Haber, J.E.2
  • 61
    • 24044463869 scopus 로고    scopus 로고
    • Mrcl is required for normal progression of replication forks throughout chromatin in S. cerevisiae
    • Szyjka SJ, Viggiani CJ, Aparicio OM (2005) Mrcl is required for normal progression of replication forks throughout chromatin in S. cerevisiae. Mol Cell 19: 691-697
    • (2005) Mol Cell , vol.19 , pp. 691-697
    • Szyjka, S.J.1    Viggiani, C.J.2    Aparicio, O.M.3
  • 62
    • 0038730929 scopus 로고    scopus 로고
    • A central role for DNA replication forks in checkpoint activation and response
    • Tercero JA, Longhese MP, Diffley JF (2003) A central role for DNA replication forks in checkpoint activation and response. Mol Cell11: 1323-1336
    • (2003) Mol Cell , vol.11 , pp. 1323-1336
    • Tercero, J.A.1    Longhese, M.P.2    Diffley, J.F.3
  • 63
    • 34249935010 scopus 로고    scopus 로고
    • Maintenance of fork integrity at damaged DNA and natural pause sites
    • Tourriere H, Pasero P (2007) Maintenance of fork integrity at damaged DNA and natural pause sites. DNA Repair (Amst) 6: 900-913
    • (2007) DNA Repair (Amst) , vol.6 , pp. 900-913
    • Tourriere, H.1    Pasero, P.2
  • 64
    • 24044552287 scopus 로고    scopus 로고
    • Mrcl and tofl promote replication fork progression and recovery independently of Rad53
    • Tourriere H, Versini G, Cordon-Preciado V, Alabert C, Pasero P (2005) Mrcl and tofl promote replication fork progression and recovery independently of Rad53. Mol Cell 19: 699-706
    • (2005) Mol Cell , vol.19 , pp. 699-706
    • Tourriere, H.1    Versini, G.2    Cordon-Preciado, V.3    Alabert, C.4    Pasero, P.5
  • 65
    • 52049108477 scopus 로고    scopus 로고
    • Multiple pathways coop- erate to facilitate DNA replication fork progression through alkylated DNA
    • Vazquez MV, Rojas V, Tercero JA (2008) Multiple pathways coop- erate to facilitate DNA replication fork progression through alkylated DNA. DNA Repair (Amst) 7: 1693-1704
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1693-1704
    • Vazquez, M.V.1    Rojas, V.2    Tercero, J.A.3
  • 66
    • 0037673943 scopus 로고    scopus 로고
    • The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments
    • Veaute X, Jeusset J, Soustelle C, Kowalczykowski SC, Le Cam E, Fabre F (2003) The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments. Nature 423: 309-312
    • (2003) Nature , vol.423 , pp. 309-312
    • Veaute, X.1    Jeusset, J.2    Soustelle, C.3    Kowalczykowski, S.C.4    Le Cam, E.5    Fabre, F.6
  • 67
    • 0344835671 scopus 로고    scopus 로고
    • The yeast Sgsl helicase is differentially required for genomic and ribosomal DNA replication
    • Versini G, Comet I, Wu M, Hoopes L, Schwob E, Pasero P (2003) The yeast Sgsl helicase is differentially required for genomic and ribosomal DNA replication. EMBO J 22: 1939-1949
    • (2003) EMBO J , vol.22 , pp. 1939-1949
    • Versini, G.1    Comet, I.2    Wu, M.3    Hoopes, L.4    Schwob, E.5    Pasero, P.6
  • 68
    • 3543045545 scopus 로고    scopus 로고
    • Role of DNA replication proteins in double-strand break-induced recombination in Saccharomyces cerevisiae
    • Wang X, Ira G, Tercero JA, Holmes AM, Diffley JFX, Haber JE (2004) Role of DNA replication proteins in double-strand break-induced recombination in Saccharomyces cerevisiae. Mol Cell Biol 24:6891-6899
    • (2004) Mol Cell Biol , vol.24 , pp. 6891-6899
    • Wang, X.1    Ira, G.2    Tercero, J.A.3    Holmes, A.M.4    Diffley, J.F.X.5    Haber, J.E.6
  • 70
    • 51549095956 scopus 로고    scopus 로고
    • Sgsl helicase and two nucleases Dna2 and exol resect DNA double-strand break ends
    • Zhu Z, Chung W-H, Shim EY, Lee SE, Ira G (2008) Sgsl helicase and two nucleases Dna2 and exol resect DNA double-strand break ends. Cell 134: 981-994
    • (2008) Cell , vol.134 , pp. 981-994
    • Zhu, Z.1    Chung, W.-H.2    Shim, E.Y.3    Lee, S.E.4    Ira, G.5
  • 71
    • 46949098616 scopus 로고    scopus 로고
    • Break dosage, cell cycle stage and DNA replication influence DNA double strand break response
    • Zierhut C, Diffley JF (2008) Break dosage, cell cycle stage and DNA replication influence DNA double strand break response. EMBO J27: 1875-1885
    • (2008) EMBO J , vol.27 , pp. 1875-1885
    • Zierhut, C.1    Diffley, J.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.