Mrc1 is required for normal progression of replication forks throughout chromatin in S. cerevisiae

Molecular Cell

Volumn 19, Issue 5, 2005, Pages 691-697

  Szyjka, Shawn J ^a   Viggiani, Christopher J ^a   Aparicio, Oscar M ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELICASE; MEDIATOR OF REPLICATION CHECKPOINT PROTEIN 1; PROTEIN; REPLISOME; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

ARTICLE; CHROMATIN; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; GENE INTERACTION; GENE LOCUS; GENETIC ANALYSIS; GENETIC STABILITY; NONHUMAN; PROTEIN FUNCTION; SACCHAROMYCES CEREVISIAE;

CELL CYCLE PROTEINS; CHROMATIN; DNA HELICASES; DNA REPLICATION; DNA-BINDING PROTEINS; MUTATION; NUCLEAR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 24044463869     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2005.06.037     Document Type: Article

References (26)

1. A.A. Alcasabas, A.J. Osborn, J. Bachant, F. Hu, P.J. Werler, K. Bousset, K. Furuya, J.F. Diffley, A.M. Carr, and S.J. Elledge Mrc1 transduces signals of DNA replication stress to activate Rad53 Nat. Cell Biol. 3 2001 958 965
2. J.G. Aparicio, C.J. Viggiani, D.G. Gibson, and O.M. Aparicio The Rpd3-Sin3 histone deacetylase regulates replication timing and enables intra-S origin control in Saccharomyces cerevisiae Mol. Cell. Biol. 24 2004 4769 4780
3. A.M. Deshpande, and C.S. Newlon DNA replication fork pause sites dependent on transcription Science 272 1996 1030 1033
4. F. Dong, S.E. Weitzel, and P.H. von Hippel A coupled complex of T4 DNA replication helicase (gp41) and polymerase (gp43) can perform rapid and processive DNA strand-displacement synthesis Proc. Natl. Acad. Sci. USA 93 1996 14456 14461
5. D.G. Gibson, J.G. Aparicio, F. Hu, and O.M. Aparicio Diminished S-Phase Cyclin-Dependent Kinase Function Elicits Vital Rad53-Dependent Checkpoint Responses in Saccharomyces cerevisiae Mol. Cell. Biol. 24 2004 10208 10222
6. A.S. Ivessa, B.A. Lenzmeier, J.B. Bessler, L.K. Goudsouzian, S.L. Schnakenberg, and V.A. Zakian The Saccharomyces cerevisiae helicase Rrm3p facilitates replication past nonhistone protein-DNA complexes Mol. Cell 12 2003 1525 1536
7. A.S. Ivessa, J.Q. Zhou, V.P. Schulz, E.K. Monson, and V.A. Zakian Saccharomyces Rrm3p, a 5′ to 3′ DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA Genes Dev. 16 2002 1383 1396
8. A.S. Ivessa, J.Q. Zhou, and V.A. Zakian The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA Cell 100 2000 479 489
9. Y. Katou, Y. Kanoh, M. Bando, H. Noguchi, H. Tanaka, T. Ashikari, K. Sugimoto, and K. Shirahige S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex Nature 424 2003 1078 1083
10. S. Kim, H.G. Dallmann, C.S. McHenry, and K.J. Marians Coupling of a replicative polymerase and helicase: A tau-DnaB interaction mediates rapid replication fork movement Cell 84 1996 643 650
11. J. Lee, A. Kumagai, and W.G. Dunphy Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17 Mol. Cell 11 2003 329 340
12. A. Lengronne, P. Pasero, A. Bensimon, and E. Schwob Monitoring S phase progression globally and locally using BrdU incorporation in TK(+) yeast strains Nucleic Acids Res. 29 2001 1433 1442
13. M.N. Nedelcheva, A. Roguev, L.B. Dolapchiev, A. Shevchenko, H.B. Taskov, A.F. Stewart, and S.S. Stoynov Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex J. Mol. Biol. 347 2005 509 521
14. S.L. Ooi, D.D. Shoemaker, and J.D. Boeke DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray Nat. Genet. 35 2003 277 286
15. A.J. Osborn, and S.J. Elledge Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53 Genes Dev. 17 2003 1755 1767
16. A.J. Osborn, S.J. Elledge, and L. Zou Checking on the fork: the DNA-replication stress-response pathway Trends Cell Biol. 12 2002 509 516
17. R. Rothstein, B. Michel, and S. Gangloff Replication fork pausing and recombination or "gimme a break" Genes Dev. 14 2000 1 10
18. F. Sar, L.A. Lindsey-Boltz, D. Subramanian, D.L. Croteau, S.Q. Hutsell, J.D. Griffith, and A. Sancar Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures J. Biol. Chem. 279 2004 39289 39295
19. K. Tanaka, and P. Russell Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1 Nat. Cell Biol. 3 2001 966 972
20. J.A. Tercero, and J.F. Diffley Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint Nature 412 2001 553 557
21. A.H. Tong, G. Lesage, G.D. Bader, H. Ding, H. Xu, X. Xin, J. Young, G.F. Berriz, R.L. Brost, and M. Chang Global mapping of the yeast genetic interaction network Science 303 2004 808 813
22. J.Z. Torres, S.L. Schnakenberg, and V.A. Zakian Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activities Mol. Cell. Biol. 24 2004 3198 3212
23. H. Tourrière, G. Versini, V. Cordón-Preciado, C. Alabert, and P. Pasero Mrc1 and Tof1 Promote Replication Fork Progression and Recovery Independently of Rad53 Mol. Cell 19 2005 699 706
24. H. Xu, C. Boone, and H.L. Klein Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage Mol. Cell. Biol. 24 2004 7082 7090
25. A. Yuzhakov, J. Turner, and M. O'Donnell Replisome assembly reveals the basis for asymmetric function in leading and lagging strand replication Cell 86 1996 877 886
26. H. Zhao, and P. Russell DNA binding domain in the replication checkpoint protein Mrc1 of Schizosaccharomyces pombe J. Biol. Chem. 279 2004 53023 53027