-
1
-
-
0035735472
-
Mrc1 transduces signals of DNA replication stress to activate Rad53
-
Alcasabas, A.A., Osborn, A.J., Bachant, J., Hu, F., Werler, P.J., Bousset, K., Furuya, K., Diffley, J.F., Carr, A.M., and Elledge, S.J. 2001. Mrc1 transduces signals of DNA replication stress to activate Rad53. Nat. Cell Biol. 3: 958-965.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 958-965
-
-
Alcasabas, A.A.1
Osborn, A.J.2
Bachant, J.3
Hu, F.4
Werler, P.J.5
Bousset, K.6
Furuya, K.7
Diffley, J.F.8
Carr, A.M.9
Elledge, S.J.10
-
2
-
-
0027953230
-
The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast
-
Allen, J.B., Zhou, Z., Siede, W., Friedberg, E.C., and Elledge, S.J. 1994. The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast. Genes & Dev. 8: 2401-2415.
-
(1994)
Genes & Dev.
, vol.8
, pp. 2401-2415
-
-
Allen, J.B.1
Zhou, Z.2
Siede, W.3
Friedberg, E.C.4
Elledge, S.J.5
-
3
-
-
0030886099
-
Components and dynamics of DNA replication complexes in S. cerevisiae: Redistribution of MCM proteins and Cdc45p during S phase
-
Aparicio, O.M., Weinstein, D.M., and Bell, S.P. 1997. Components and dynamics of DNA replication complexes in S. cerevisiae: Redistribution of MCM proteins and Cdc45p during S phase. Cell 91: 59-69.
-
(1997)
Cell
, vol.91
, pp. 59-69
-
-
Aparicio, O.M.1
Weinstein, D.M.2
Bell, S.P.3
-
4
-
-
0029592020
-
Dpb11, which interacts with DNA polymerase II(ε) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint
-
Araki, H., Leem, S.H., Phongdara, A., and Sugino, A. 1995. Dpb11, which interacts with DNA polymerase II(ε) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint. Proc. Natl. Acad. Sci. 92: 11791-11795.
-
(1995)
Proc. Natl. Acad. Sci.
, vol.92
, pp. 11791-11795
-
-
Araki, H.1
Leem, S.H.2
Phongdara, A.3
Sugino, A.4
-
5
-
-
0032079366
-
RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation
-
de la Torre-Ruiz, M.A., Green, C.M., and Lowndes, N.F. 1998. RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation. EMBO J. 17: 2687-2698.
-
(1998)
EMBO J.
, vol.17
, pp. 2687-2698
-
-
De la Torre-Ruiz, M.A.1
Green, C.M.2
Lowndes, N.F.3
-
6
-
-
0032530824
-
Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway
-
Desany, B.A., Alcasabas, A.A., Bachant, J.B., and Elledge, S.J. 1998. Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Genes & Dev. 12: 2956-2970.
-
(1998)
Genes & Dev.
, vol.12
, pp. 2956-2970
-
-
Desany, B.A.1
Alcasabas, A.A.2
Bachant, J.B.3
Elledge, S.J.4
-
7
-
-
0035162698
-
Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p
-
Gasch, A.P., Huang, M., Metzner, S., Botstein, D., Elledge, S.J., and Brown, P.O. 2001. Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. Mol. Biol. Cell 12: 2987-3003.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2987-3003
-
-
Gasch, A.P.1
Huang, M.2
Metzner, S.3
Botstein, D.4
Elledge, S.J.5
Brown, P.O.6
-
8
-
-
0034881760
-
Budding yeast Rad9 is an ATP-dependent Rad53 activating machine
-
Gilbert, C.S., Green, C.M., and Lowndes, N.F. 2001. Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. Mol. Cell 8: 129-136.
-
(2001)
Mol. Cell
, vol.8
, pp. 129-136
-
-
Gilbert, C.S.1
Green, C.M.2
Lowndes, N.F.3
-
9
-
-
0032483576
-
The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor
-
Huang, M., Zhou, Z., and Elledge, S.J. 1998. The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor. Cell 94: 595-605.
-
(1998)
Cell
, vol.94
, pp. 595-605
-
-
Huang, M.1
Zhou, Z.2
Elledge, S.J.3
-
10
-
-
0003747499
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Kaiser, C., Michaelis, S., and Mitchell, A. 1994. Methods in yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(1994)
Methods in Yeast Genetics
-
-
Kaiser, C.1
Michaelis, S.2
Mitchell, A.3
-
11
-
-
0031658237
-
Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication
-
Kamimura, Y., Masumoto, H., Sugino, A., and Araki, H. 1998. Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication. Mol. Cell. Biol. 18: 6102-6109.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6102-6109
-
-
Kamimura, Y.1
Masumoto, H.2
Sugino, A.3
Araki, H.4
-
12
-
-
0033621392
-
Substrate specificities and identification of putative substrates of ATM kinase family members
-
Kim, S.T., Lim, D.S., Canman, C.E., and Kastan, M.B. 1999. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274: 37538-37543.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37538-37543
-
-
Kim, S.T.1
Lim, D.S.2
Canman, C.E.3
Kastan, M.B.4
-
13
-
-
0035955398
-
Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms
-
Kondo, T., Wakayama, T., Naiki, T., Matsumoto, K., and Sugimoto, K. 2001. Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms. Science 294: 867-870.
-
(2001)
Science
, vol.294
, pp. 867-870
-
-
Kondo, T.1
Wakayama, T.2
Naiki, T.3
Matsumoto, K.4
Sugimoto, K.5
-
14
-
-
0033634679
-
Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts
-
Kumagai, A. and Dunphy, W.G. 2000. Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts. Mol. Cell 6: 839-849.
-
(2000)
Mol. Cell
, vol.6
, pp. 839-849
-
-
Kumagai, A.1
Dunphy, W.G.2
-
15
-
-
0037291130
-
Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17
-
Lee, J., Kumagai, A., and Dunphy, W.G. 2003. Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17. Mol. Cell 11: 329-340.
-
(2003)
Mol. Cell
, vol.11
, pp. 329-340
-
-
Lee, J.1
Kumagai, A.2
Dunphy, W.G.3
-
16
-
-
0030804309
-
The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast
-
Longhese, M.P., Paciotti, V., Fraschini, R., Zaccarini, R., Plevani, P., and Lucchini, G. 1997. The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast. EMBO J. 16: 5216-5226.
-
(1997)
EMBO J.
, vol.16
, pp. 5216-5226
-
-
Longhese, M.P.1
Paciotti, V.2
Fraschini, R.3
Zaccarini, R.4
Plevani, P.5
Lucchini, G.6
-
17
-
-
0031820288
-
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
-
Longtine, M.S., McKenzie III, A., Demarini, D.J., Shah, N.G., Wach, A., Brachat, A., Philippsen, P., and Pringle, J.R. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14: 953-961.
-
(1998)
Yeast
, vol.14
, pp. 953-961
-
-
Longtine, M.S.1
McKenzie A. III2
Demarini, D.J.3
Shah, N.G.4
Wach, A.5
Brachat, A.6
Philippsen, P.7
Pringle, J.R.8
-
18
-
-
0035797383
-
The DNA replication checkpoint response stabilizes stalled replication forks
-
Lopes, M., Cotta-Ramusino, C., Pellicioli, A., Liberi, G., Plevani, P., Muzi-Falconi, M., Newlon, C.S., and Foiani, M. 2001. The DNA replication checkpoint response stabilizes stalled replication forks. Nature 412: 557-561.
-
(2001)
Nature
, vol.412
, pp. 557-561
-
-
Lopes, M.1
Cotta-Ramusino, C.2
Pellicioli, A.3
Liberi, G.4
Plevani, P.5
Muzi-Falconi, M.6
Newlon, C.S.7
Foiani, M.8
-
19
-
-
0035498938
-
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
-
Melo, J.A., Cohen, J., and Toczyski, D.P. 2001. Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes & Dev. 15: 2809-2821.
-
(2001)
Genes & Dev.
, vol.15
, pp. 2809-2821
-
-
Melo, J.A.1
Cohen, J.2
Toczyski, D.P.3
-
20
-
-
0034903652
-
Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway
-
Naiki, T., Kondo, T., Nakada, D., Matsumoto, K., and Sugimoto, K. 2001. Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway. Mol. Cell. Biol. 21: 5838-5845.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5838-5845
-
-
Naiki, T.1
Kondo, T.2
Nakada, D.3
Matsumoto, K.4
Sugimoto, K.5
-
21
-
-
0028979332
-
DNA polymerase ε links the DNA replication machinery to the S phase checkpoint
-
Navas, T.A., Zhou, Z., and Elledge, S.J. 1995. DNA polymerase ε links the DNA replication machinery to the S phase checkpoint. Cell 80: 29-39.
-
(1995)
Cell
, vol.80
, pp. 29-39
-
-
Navas, T.A.1
Zhou, Z.2
Elledge, S.J.3
-
22
-
-
0029859168
-
RAD9 and DNA polymerase ε form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae
-
Navas, T.A., Sanchez, Y., and Elledge, S.J. 1996. RAD9 and DNA polymerase ε form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae. Genes & Dev. 10: 2632-2643.
-
(1996)
Genes & Dev.
, vol.10
, pp. 2632-2643
-
-
Navas, T.A.1
Sanchez, Y.2
Elledge, S.J.3
-
23
-
-
0034663809
-
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast
-
Paciotti, V., Clerici, M., Lucchini, G., and Longhese, M.P. 2000. The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. Genes & Dev. 14: 2046-2059.
-
(2000)
Genes & Dev.
, vol.14
, pp. 2046-2059
-
-
Paciotti, V.1
Clerici, M.2
Lucchini, G.3
Longhese, M.P.4
-
24
-
-
0034329474
-
LCD1: An essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae
-
Rouse, J. and Jackson, S.P. 2000. LCD1: An essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae. EMBO J. 19: 5801-5812.
-
(2000)
EMBO J.
, vol.19
, pp. 5801-5812
-
-
Rouse, J.1
Jackson, S.P.2
-
25
-
-
0030593033
-
Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
-
Sanchez, Y., Desany, B.A., Jones, W.J., Liu, Q., Wang, B., and Elledge, S.J. 1996. Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science 271: 357-360.
-
(1996)
Science
, vol.271
, pp. 357-360
-
-
Sanchez, Y.1
Desany, B.A.2
Jones, W.J.3
Liu, Q.4
Wang, B.5
Elledge, S.J.6
-
26
-
-
0036281710
-
Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint
-
Schwartz, M.F., Duong, J.F., Sun, Z., Morrow, J.S., Pradhan, D., and Stern, D.F. 2002. Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint. Mol. Cell 9: 1055-1065.
-
(2002)
Mol. Cell
, vol.9
, pp. 1055-1065
-
-
Schwartz, M.F.1
Duong, J.F.2
Sun, Z.3
Morrow, J.S.4
Pradhan, D.5
Stern, D.F.6
-
27
-
-
0037115462
-
ORC and the intra-S-phase checkpoint: A threshold regulates Rad53p activation in S phase
-
Shimada, K., Pasero, P., and Gasser, S.M. 2002. ORC and the intra-S-phase checkpoint: A threshold regulates Rad53p activation in S phase. Genes & Dev. 16: 3236-3252.
-
(2002)
Genes & Dev.
, vol.16
, pp. 3236-3252
-
-
Shimada, K.1
Pasero, P.2
Gasser, S.M.3
-
28
-
-
0031027431
-
SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
-
Strahl-Bolsinger, S., Hecht, A., Luo, K., and Grunstein, M. 1997. SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes & Dev. 11: 83-93.
-
(1997)
Genes & Dev.
, vol.11
, pp. 83-93
-
-
Strahl-Bolsinger, S.1
Hecht, A.2
Luo, K.3
Grunstein, M.4
-
29
-
-
0030793718
-
Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway
-
Sugimoto, K., Ando, S., Shimomura, T., and Matsumoto, K. 1997. Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway. Mol. Cell. Biol. 17: 5905-5914.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5905-5914
-
-
Sugimoto, K.1
Ando, S.2
Shimomura, T.3
Matsumoto, K.4
-
30
-
-
0029928222
-
Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways
-
Sun, Z., Fay, D.S., Marini, F., Foiani, M., and Stern, D.F. 1996. Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways. Genes & Dev. 10: 395-406.
-
(1996)
Genes & Dev.
, vol.10
, pp. 395-406
-
-
Sun, Z.1
Fay, D.S.2
Marini, F.3
Foiani, M.4
Stern, D.F.5
-
31
-
-
0032504069
-
Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint
-
Sun, Z., Hsiao, J., Fay, D.S., and Stern, D.F. 1998. Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint. Science 281: 272-274.
-
(1998)
Science
, vol.281
, pp. 272-274
-
-
Sun, Z.1
Hsiao, J.2
Fay, D.S.3
Stern, D.F.4
-
32
-
-
0035736486
-
Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1
-
Tanaka, K. and Russell, P. 2001. Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1. Nat. Cell Biol. 3: 966-972.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 966-972
-
-
Tanaka, K.1
Russell, P.2
-
33
-
-
0035797444
-
Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint
-
Tercero, J.A. and Diffley, J.F. 2001. Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint. Nature 412: 553-557.
-
(2001)
Nature
, vol.412
, pp. 553-557
-
-
Tercero, J.A.1
Diffley, J.F.2
-
34
-
-
0029157031
-
Segregation of unreplicated chromosomes in Saccharomyces cerevisiae reveals a novel G1/M-phase checkpoint
-
Toyn, J.H., Johnson, A.L., and Johnston, L.H. 1995. Segregation of unreplicated chromosomes in Saccharomyces cerevisiae reveals a novel G1/M-phase checkpoint. Mol. Cell. Biol. 15: 5312-5321.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5312-5321
-
-
Toyn, J.H.1
Johnson, A.L.2
Johnston, L.H.3
-
35
-
-
0032189952
-
The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage
-
Vialard, J.E., Gilbert, C.S., Green, C.M., and Lowndes, N.F. 1998. The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage. EMBO J. 17: 5679-5688.
-
(1998)
EMBO J.
, vol.17
, pp. 5679-5688
-
-
Vialard, J.E.1
Gilbert, C.S.2
Green, C.M.3
Lowndes, N.F.4
-
36
-
-
0035138557
-
Pie1, a protein interacting with Mec1, controls cell growth and checkpoint responses in Saccharomyces cerevisiae
-
Wakayama, T., Kondo, T., Ando, S., Matsumoto, K., and Sugimoto, K. 2001. Pie1, a protein interacting with Mec1, controls cell growth and checkpoint responses in Saccharomyces cerevisiae. Mol. Cell. Biol. 21: 755-764.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 755-764
-
-
Wakayama, T.1
Kondo, T.2
Ando, S.3
Matsumoto, K.4
Sugimoto, K.5
-
37
-
-
0033616679
-
DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae
-
Wang, H. and Elledge, S.J. 1999. DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. 96: 3824-3829.
-
(1999)
Proc. Natl. Acad. Sci.
, vol.96
, pp. 3824-3829
-
-
Wang, H.1
Elledge, S.J.2
-
38
-
-
0036237806
-
Genetic and physical interactions between DPB11 and DDC1 in the yeast DNA damage response pathway
-
2002. Genetic and physical interactions between DPB11 and DDC1 in the yeast DNA damage response pathway. Genetics 160: 1295-1304.
-
(2002)
Genetics
, vol.160
, pp. 1295-1304
-
-
-
39
-
-
0023712476
-
The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae
-
Weinert, T.A. and Hartwell, L.H. 1988. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science 241: 317-322.
-
(1988)
Science
, vol.241
, pp. 317-322
-
-
Weinert, T.A.1
Hartwell, L.H.2
-
40
-
-
0027212282
-
Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint
-
1993. Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint. Genetics 134: 63-80.
-
(1993)
Genetics
, vol.134
, pp. 63-80
-
-
-
41
-
-
0028353634
-
Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
-
Weinert, T.A., Kiser, G.L., and Hartwell, L.H. 1994. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes & Dev. 8: 652-665.
-
(1994)
Genes & Dev.
, vol.8
, pp. 652-665
-
-
Weinert, T.A.1
Kiser, G.L.2
Hartwell, L.H.3
-
42
-
-
0033215306
-
Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway
-
Weinreich, M. and Stillman, B. 1999. Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway. EMBO J. 18: 5334-5346.
-
(1999)
EMBO J.
, vol.18
, pp. 5334-5346
-
-
Weinreich, M.1
Stillman, B.2
-
43
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou, B.B. and Elledge, S.J. 2000. The DNA damage response: Putting checkpoints in perspective. Nature 408: 433-439.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
44
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou, L. and Elledge, S.J. 2003. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300: 1542-1548.
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
-
45
-
-
0032562610
-
Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin
-
Zou, L. and Stillman, B. 1998. Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Science 280: 593-596.
-
(1998)
Science
, vol.280
, pp. 593-596
-
-
Zou, L.1
Stillman, B.2
|