Inflammatory bowel disease: An impaired barrier disease

Langenbeck's Archives of Surgery

Volumn 398, Issue 1, 2013, Pages 1-12

  Jäger, Simon ^a   Stange, Eduard F ^a   Wehkamp, Jan ^a,b  

^a ROBERT BOSCH HOSPITAL   (Germany)

^b DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

Author keywords

Crohn's disease pathogenesis; Defensin; Inflammatory bowel disease; Innate immunity; Paneth cell

Indexed keywords

ALPHA DEFENSIN; ALPHA DEFENSIN 5; ALPHA DEFENSIN 6; BACTERICIDAL PERMEABILITY INCREASING PROTEIN; BETA DEFENSIN; BETA DEFENSIN 1; BETA DEFENSIN 103; BETA DEFENSIN 104; BETA DEFENSIN 2; BETA DEFENSIN 3; BETA DEFENSIN 4; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; DEFENSIN; DEFENSIN 5; DEFENSIN 6; ELAFIN; LYSOZYME; PANCREATITIS ASSOCIATED PROTEIN; PHOSPHATIDYLCHOLINE; POLYPEPTIDE ANTIBIOTIC AGENT; SECRETORY PHOSPHOLIPASE A2; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; CONSERVATIVE TREATMENT; CROHN DISEASE; DISEASE ASSOCIATION; DRUG EFFECT; HUMAN; ILEOCECAL VALVE; INNATE IMMUNITY; INTESTINE FLORA; INTESTINE MUCOSA; MUCUS; NONHUMAN; PANETH CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN SECRETION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT PLANNING; TRICHURIS SUIS; ULCERATIVE COLITIS; WORM EGG;

ANTIMICROBIAL CATIONIC PEPTIDES; COLITIS, ULCERATIVE; CROHN DISEASE; DEFENSINS; DNA MUTATIONAL ANALYSIS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNITY, INNATE; IMMUNOGENETICS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; INTESTINAL MUCOSA; INTESTINE, LARGE; INTESTINE, SMALL; NOD2 SIGNALING ADAPTOR PROTEIN; PANETH CELLS; POUCHITIS; RISK FACTORS; RNA, MESSENGER;

EID: 84871755412     PISSN: 14352443     EISSN: 14352451     Source Type: Journal    
DOI: 10.1007/s00423-012-1030-9     Document Type: Review

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