Paneth cell trypsin is the processing enzyme for human defensin-5

Nature Immunology

Volumn 3, Issue 6, 2002, Pages 583-590

  Ghosh, Dipankar ^a   Porter, Edith ^b,c   Shen, Bo ^a   Lee, Sarah K ^a   Wilk, Dennis ^a   Drazba, Judith ^a   Yadav, Satya P ^a   Crabb, John W ^a   Ganz, Tomas ^b   Bevins, Charles L ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ALPHA DEFENSIN; ALPHA DEFENSIN 5; ARGININE; DEFENSIN; ISOENZYME; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN PRECURSOR; THREONINE; TRYPSIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME LOCALIZATION; HUMAN; HUMAN TISSUE; IMMUNOREGULATION; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA; PANETH CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN PROCESSING; SECRETORY CELL; SECRETORY VESICLE; STORAGE; SURFACE PROPERTY;

ALPHA-DEFENSINS; AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; DNA, COMPLEMENTARY; HUMANS; IMMUNITY, MUCOSAL; MOLECULAR SEQUENCE DATA; PANETH CELLS; PROTEIN ISOFORMS; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, MESSENGER; TISSUE DISTRIBUTION; TRYPSIN;

EID: 0036079594     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni797     Document Type: Article

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