For Bugs in Bile: The Times They Are A-Changin'

Gastroenterology

Volumn 136, Issue 4, 2009, Pages 1164-1167

  Stange, Eduard F ^a  

^a ROBERT BOSCH HOSPITAL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN 1; BETA DEFENSIN 2; BETA DEFENSIN 4; BILE SALT; BUTYRIC ACID; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CHOLESTEROL; COLECALCIFEROL; DEFENSIN; ELAFIN; FARNESOID X RECEPTOR; LIPOPROTEIN; LYSOZYME; PANCREATITIS ASSOCIATED PROTEIN; POLYPEPTIDE ANTIBIOTIC AGENT; URSODEOXYCHOLIC ACID;

BACTERIAL FLORA; BACTERIAL INFECTION; BILE DUCT STONE; CROHN DISEASE; DEFENSE MECHANISM; DRUG MECHANISM; EDITORIAL; HUMAN; IMMUNE RESPONSE; INNATE IMMUNITY; INTESTINE FLORA; NONHUMAN; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHIGELLOSIS; T LYMPHOCYTE;

EID: 62949166623     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.02.020     Document Type: Editorial

References (31)

1. Ding J.W., Andersson R., Soltesz V., et al. The role of bile and bile acids in bacterial translocation in obstructive jaundice in rats. Eur Surg Res 25 (1993) 11-19
2. Westergaard H., and Dietschy J.M. The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell. J Clin Invest 58 (1976) 97-108
3. Dietschy J.M., and Siperstein M.D. Effect of cholesterol feeding and fasting on sterol synthesis in seventeen tissues of the rat. J Lipid Res 8 (1967) 97-104
4. Stange E.F., Scheibner J., and Ditschuneit H. Role of primary and secondary bile acids as feedback inhibitors of bile acid synthesis in the rat in vivo. J Clin Invest 84 (1989) 173-180
5. Dylan B. Lyrics: 1962-2001 (2005), Simon & Schuster, New York
6. Meier P.J., and Stieger B. Bile salt transporters. Annu Rev Physiol 64 (2002) 635-661
7. Yu L., Hammer R.E., Li-Hawkins J., et al. Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc Natl Acad Sci U S A 99 (2002) 16237-16242
8. Valasek M.A., Repa J.J., Quan G., et al. Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters. Am J Physiol Gastrointest Liver Physiol 295 (2008) G813-G822
9. Eloranta J.J., and Kullak-Ublick G.A. The role of FXR in disorders of bile acid homeostasis. Physiology (Bethesda) 23 (2008) 286-295
10. Kruit J.K., Groen A.K., van Berkel T.J., et al. Emerging roles of the intestine in control of cholesterol metabolism. World J Gastroenterol 12 (2006) 6429-6439
11. Bergheim I., Harsch S., Mueller O., et al. Apical sodium bile acid transporter and ileal lipid binding protein in gallstone carriers. J Lipid Res 47 (2006) 42-50
12. Buch S., Schafmayer C., Volzke H., et al. A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease. Nat Genet 39 (2007) 995-999
13. Renner O., Harsch S., Strohmeyer A., et al. Reduced ileal expression of OSTalpha-OSTbeta in non-obese gallstone disease. J Lipid Res 49 (2008) 2045-2054
14. Stange E.F., and Dietschy J.M. The origin of cholesterol in the mesenteric lymph of the rat. J Lipid Res 26 (1985) 175-184
15. Boman H.G., Nilsson I., and Rasmuson B. Inducible antibacterial defence system in Drosophila. Nature 237 (1972) 232-235
16. Zasloff M. Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad Sci U S A 84 (1987) 5449-5453
17. Wehkamp J., Schauber J., and Stange E.F. Defensins and cathelicidins in gastrointestinal infections. Curr Opin Gastroenterol 23 (2007) 32-38
18. Jones D.E., and Bevins C.L. Paneth cells of the human small intestine express an antimicrobial peptide gene. J Biol Chem 267 (1992) 23216-23225
19. Wehkamp J., Schmidt K., Herrlinger K.R., et al. Defensin pattern in chronic gastritis: HBD-2 is differentially expressed with respect to Helicobacter pylori status. J Clin Pathol 56 (2003) 352-357
20. Wehkamp J., Schmid M., and Stange E.F. Defensins and other antimicrobial peptides in inflammatory bowel disease. Curr Opin Gastroenterol 23 (2007) 370-378
21. Wehkamp J., Salzman N.H., Porter E., et al. Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci U S A 102 (2005) 18129-18134
22. Nuding S., Fellermann K., Wehkamp J., et al. Reduced mucosal antimicrobial activity in Crohn's disease of the colon. Gut 56 (2007) 1240-1247
23. Inagaki T., Moschetta A., Lee Y.K., et al. Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor. Proc Natl Acad Sci U S A 103 (2006) 3920-3925
24. Chen X.M., O'Hara S.P., and LaRusso N.F. The immunobiology of cholangiocytes. Immunol Cell Biol 86 (2008) 497-505
25. Harada K., Ohba K., Ozaki S., et al. Peptide antibiotic human beta-defensin-1 and -2 contribute to antimicrobial defense of the intrahepatic biliary tree. Hepatology 40 (2004) 925-932
26. d'Aldebert E., Mve, M-J B.B., Mergey M., et al. Bile salts control the antimicrobial peptide cathelicidin through nuclear receptors in the human biliary epithelium. Gastroenterology 136 (2009) 1435-1443
27. Zanetti M. Cathelicidins, multifunctional peptides of the innate immunity. J Leukoc Biol 75 (2004) 39-48
28. Wang T.T., Nestel F.P., Bourdeau V., et al. 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J Immunol 173 (2004) 2909-2912
29. Raqib R., Sarker P., Bergman P., et al. Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic. Proc Natl Acad Sci U S A 103 (2006) 9178-9183
30. Lazaridis K.N., Strazzabosco M., and LaRusso N.F. The cholangiopathies: disorders of biliary epithelia. Gastroenterology 127 (2004) 1565-1577
31. Wang Y.D., Chen W.D., Wang M., et al. Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response. Hepatology 48 (2008) 1632-1643