Human α-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets

Science

Volumn 337, Issue 6093, 2012, Pages 477-481

  Chu, Hiutung ^a   Pazgier, Marzena ^b   Jung, Grace ^c   Nuccio, Sean Paul ^a   Castillo, Patricia A ^a   De Jong, Maarten F ^a   Winter, Maria G ^a   Winter, Sebastian E ^a   Wehkamp, Jan ^a,g   Shen, Bo ^d   Salzman, Nita H ^e   Underwood, Mark A ^a   Tsolis, Renee M ^a   Young, Glenn M ^f   Lu, Wuyuan ^b   Lehrer, Robert I ^c   Bäumler, Andreas J ^a   Bevins, Charles L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

^e MEDICAL COLLEGE OF WISCONSIN   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DEFENSIN; ALPHA DEFENSIN 6; HISTIDINE; INVASIN; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; DATA SET; GENE EXPRESSION; IMMUNITY; INSECTICIDE; MUCUS; PATHOGENICITY; PEPTIDE; PROTEIN; STOCHASTICITY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL IMMUNITY; CELL INVASION; CONTROLLED STUDY; CRYSTAL STRUCTURE; FIBER; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SALMONELLA TYPHIMURIUM; SMALL INTESTINE MUCOSA;

BACTERIA (MICROORGANISMS); HOMINIDAE;

EID: 84864335926     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1218831     Document Type: Article

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