The structural basis of force generation by the mitotic motor kinesin-5

Journal of Biological Chemistry

Volumn 287, Issue 53, 2012, Pages 44654-44666

  Goulet, Adeline ^a   Behnke Parks, William M ^b   Sindelar, Charles V ^c   Major, Jennifer ^d   Rosenfeld, Steven S ^d   Moores, Carolyn A ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c YALE UNIVERSITY   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC INHIBITOR; ANTI-CANCER THERAPEUTICS; ATP BINDING; BIPOLAR SPINDLES; CONFORMATIONAL CHANGE; CRYO-ELECTRON MICROSCOPY; FORCE GENERATION; MECHANICAL ELEMENTS; MICROTUBULES; MITOTIC MOTOR; MOLECULAR MECHANISM; MOTOR DOMAIN; N-TERMINALS; NORMAL FUNCTION; NUCLEOTIDE BINDING; SEQUENCE VARIATIONS; STRUCTURAL BASIS; SUBNANOMETER RESOLUTION;

BINDING SITES; DOCKING;

NUCLEOTIDES;

ADENOSINE TRIPHOSPHATE; KINESIN 5; NUCLEOTIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; ENZYME BINDING; ENZYME CONFORMATION; MOLECULAR DOCKING; NUCLEOTIDE BINDING SITE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

BINDING SITES; HUMANS; KINESIN; KINETICS; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; MODELS, MOLECULAR; NUCLEOTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

INVERTEBRATA;

EID: 84871744734     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.404228     Document Type: Article

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