Monastrol inhibition of the mitotic kinesin Eg5

Journal of Biological Chemistry

Volumn 280, Issue 13, 2005, Pages 12658-12667

  Cochran, Jared C ^a   Gatial III, Joseph E ^a   Kapoor, Tarun M ^b   Gilbert, Susan P ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; HYDROLYSIS; ISOMERIZATION; KINETIC THEORY;

BIPOLAR SPINDLES; MITOTIC KINESIN EG5;

ENZYME INHIBITION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; KINESIN; MONASTROL; MONOMER; PROTEIN EG5; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONFORMATION; ENZYME ACTIVITY; HYDROLYSIS; INHIBITION KINETICS; ISOMERIZATION; KINETICS; MICROTUBULE; MITOSIS; PRIORITY JOURNAL; PROTEIN BINDING; STEADY STATE; SYNTHESIS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROLYSIS; KINESIN; KINETICS; MICROTUBULES; MITOTIC SPINDLE APPARATUS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; NUCLEOTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PYRIMIDINES; THIONES; TIME FACTORS;

EID: 16844373381     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413140200     Document Type: Article

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