ATPase mechanism of Eg5 in the absence of microtubules: Insight into microtubule activation and allosteric inhibition by monastrol

Biochemistry

Volumn 44, Issue 50, 2005, Pages 16633-16648

  Cochran, Jared C ^a   Gilbert, Susan P ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b A518 Langley Hall ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CONFORMATIONS; ENZYMES; HYDROLYSIS; ISOMERIZATION; REACTION KINETICS;

CONFORMATIONAL CHANGE; ENZYMATIC EFFICIENCY; MICROTUBULE ACTIVATION; MONASTROL;

ADENOSINETRIPHOSPHATE;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; KINESIN; MONASTROL; MONOMER; NUCLEOTIDE; PHOSPHATE; PROTEIN EG5; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ACCELERATION; ALLOSTERISM; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME MECHANISM; HYDROLYSIS; ISOMERIZATION; KINETICS; MICROTUBULE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; STEADY STATE;

ACRYLAMIDE; ADENOSINE TRIPHOSPHATASES; ALLOSTERIC REGULATION; ENZYME ACTIVATION; HYDROLYSIS; KINESIN; KINETICS; MICROTUBULES; PROTEIN CONFORMATION; PYRIMIDINES; SPECTROMETRY, FLUORESCENCE; THIONES;

EID: 29244476067     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051724w     Document Type: Article

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