Cholesterol-dependent energy transfer between fluorescent proteins-insights into protein proximity of APP and BACE1 in different membranes in Niemann-pick type C disease cells

International Journal of Molecular Sciences

Volumn 13, Issue 12, 2012, Pages 15801-15812

  von Einem, Bjoern ^a   Weber, Petra ^b   Wagner, Michael ^b   Malnar, Martina ^c   Kosicek, Marko ^c   Hecimovic, Silva ^c   von Arnim, Christine A F ^a   Schneckenburger, Herbert ^b  

^a UNIVERSITY OF ULM   (Germany)

^b AALEN UNIVERSITY   (Germany)

^c RUDER BO KOVI INSTITUTE   (Croatia)

Author keywords

APP; BACE1; Cholesterol; FRET; Generalized polarization; Laurdan; Neurodegeneration; NPC; TIRFM

Indexed keywords

BETA SECRETASE 1; CHOLESTEROL; GREEN FLUORESCENT PROTEIN; LAURDAN; AMYLOID PRECURSOR PROTEIN; APP PROTEIN, HUMAN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; CARRIER PROTEIN; MEMBRANE PROTEIN; NPC1 PROTEIN, HUMAN; SECRETASE;

ANIMAL CELL; ARTICLE; CELL LEVEL; CELLULAR DISTRIBUTION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENDOSOME; FEMALE; FLUORESCENCE MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; INTERNAL ILLUMINATION FLUORESCENCE MICROSCOPY; INTRACELLULAR TRANSPORT; LIPID ANALYSIS; LIPID STORAGE; LYSOSOME; MEMBRANE FLUIDITY; MOLECULAR PATHOLOGY; NIEMANN PICK DISEASE; NONHUMAN; WILD TYPE; ANIMAL; CELL MEMBRANE; CHO CELL LINE; CRICETULUS; GENE DELETION; GENETICS; HAMSTER; HUMAN; METABOLISM; PATHOLOGY; PROCEDURES;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; CARRIER PROTEINS; CELL MEMBRANE; CHO CELLS; CHOLESTEROL; CRICETINAE; CRICETULUS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE DELETION; GREEN FLUORESCENT PROTEINS; HUMANS; MEMBRANE GLYCOPROTEINS; NIEMANN-PICK DISEASE, TYPE C;

EID: 84871675225     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms131215801     Document Type: Article

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