Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease

Journal of Neuroscience

Volumn 25, Issue 43, 2005, Pages 9932-9939

  Valenza, Marta ^a   Rigamonti, Dorotea ^a   Goffredo, Donato ^a   Zuccato, Chiara ^a   Fenu, Simone ^a   Jamot, Laure ^b   Strand, Andrew ^c   Tarditi, Alessia ^a   Woodman, Ben ^d   Racchi, Marco ^e   Mariotti, Caterina ^f   Di Donate, Stefano ^f   Corsini, Alberto ^a   Bates, Gillian ^d   Pruss, Rebecca ^b   Olson, James M ^c   Sipione, Simonetta ^g   Tartari, Marzia ^a   Cattaneo, Elena ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b Trophos   (France)

^c Fred Hutchinson Cancer Research Center   (United States)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF PAVIA   (Italy)

^f DEPARTMENT OF NEUROSURGERY   (Italy)

^g UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Degeneration; GABAergic neurons; Huntington's disease; Lipids; Neuronal death; Transcription factor

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; CHOLESTEROL; HUNTINGTIN; STEROL REGULATORY ELEMENT BINDING PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BRAIN TISSUE; CELL CULTURE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; HUNTINGTON CHOREA; PRIORITY JOURNAL;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELL DEATH; CELLS, CULTURED; CHOLESTEROL; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; HUNTINGTON DISEASE; HYDROXYMETHYLGLUTARYL COA REDUCTASES; IMMUNOHISTOCHEMISTRY; MICE; NEURONS; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PROTEIN TRANSPORT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TIME FACTORS; TRANSFECTION;

EID: 27344444843     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3355-05.2005     Document Type: Article

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