Rational design of nascent metalloenzymes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 12, 2000, Pages 6292-6297

  Benson, David E ^a   Wisz, Michael S ^a   Hellinga, Homme W ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; M PROTEIN; OXYGEN;

ARTICLE; BINDING SITE; CHEMICAL REACTION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; MOLECULAR EVOLUTION; PRIORITY JOURNAL;

CATALYSIS; ENZYMES; METALLOPROTEINS; METALS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPEROXIDE DISMUTASE;

EID: 0034612312     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.12.6292     Document Type: Article

References (65)

1. Hellinga, H. W. (1996) in Protein Engineering: Principles and Practice, eds. Cleland, J. L. & Craik, C. S. (Wiley-Liss, New York), pp. 369-398.
2. Bryson, J. W., Betz, S. F., Lu, H. S., Suich, D. J., Zhou, H. X., O'Neil, K. T. & DeGrado, W. F. (1995) Science 270, 935-941.
3. Regan, L. (1995) Trends Biochem. Sci. 20, 280-285.
4. Malakauskas, S. M. & Mayo, S. L. (1998) Nat. Struct. Biol. 5, 470-475.
5. Hellinga, H. W. (1998) Nat. Struct. Biol. 5, 525-527.
6. DeGrado, W. F., Summa, C. M., Pavone, V., Nastri, F. & Lombardi, A. (1999) Annu. Rev. Biochem. 68, 779-819.
7. Lu, Y. & Valentine, J. S. (1997) Curr. Opin. Struct. Biol. 7, 495-500.
8. Pabo, C. (1983) Nature (London) 301, 200.
9. Knowles, J. R. (1987) Science 236, 1252-1258.
10. DeGrado, W. F. (1993) Nature (London) 365, 488-489.
11. Distefano, M. D., Kuang, H., Qi, D. F. & Mazhary, A. (1998) Curr. Opin. Struct. Biol. 8, 459-465.
12. Benson, D. E., Wisz, M. S. & Hellinga, H. W. (1998) Curr. Opin. Biotechnol. 9, 370-376.
13. Hahn, K. W., Klis, W. A. & Stewart, J. M. (1990) Science 248, 1544-1547.
14. Corey, M. J. & Corey, E. (1996) Proc. Natl. Acad. Sci. USA 93, 11428-11434.
15. Davies, R. R. & Distefano, M. D. (1997) J. Am. Chem. Soc. 119, 11643-11652.
16. Kuang, H., Davies, R. R. & Distefano, M. D. (1997) Bioorg. Med. Chem. Lett. 7, 2055-2060.
17. Quemeneur, E., Moutiez, M., Charbonnier, J. B. & Menez, A. (1998) Nature (London) 391, 301-304.
18. Kaim, W. & Schewderski, B. (1994) Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life (Wiley, New York).
19. Que, L. J. & Ho, R. Y. N. (1996) Chem. Rev. 96, 2607-2624.
20. Kitajima, N. & Tolman, W. B. (1995) Prog. Inorg. Chem. 43, 419-531.
21. Feig, A. L. & Lippard, S. J. (1994) Chem. Rev. 94, 759-805.
22. Bilinski, T. (1991) Biosystems 24, 305-312.
23. Sawyer, D. T. (1991) Oxygen Chemistry (Oxford Univ. Press, New York).
24. Valentine, J. S. (1994) in Bioinorganic Chemistry, eds. Bertini, I., Gray, H. B., Lippard, S. J. & Valentine, J. S. (University Science, Mill Valley, CA), pp. 253-313.
25. Valentine, J., Wertz, D., Lyons, T., Liou, L., Goto, J. & Gralla, E. (1998) Curr. Opin. Chem. Biol. 2, 253-262.
26. McCord, J. M. & Fridovich, I. (1969) J. Biol. Chem. 244, 6049-6055.
27. Yost, F. J. & Fridovich, I. (1973) J. Biol. Chem. 248, 4905-4908.
28. Gregroy, E. M., Yost, F. J., Jr. & Fridovich, I. (1973) J. Bacteriol. 115, 987-991.
29. Walling, C. (1975) Acc. Chem. Res. 8, 125-132.
30. Goto, J. J., Gralla, E. B., Valentine, J. S. & Cabelli, D. E. (1998) J. Biol. Chem. 273, 30104-30109.
31. Waggoner, D. J., Bartnikas, T. B. & Gitlin, J. D. (1999) Neurobiol. Dis. 6, 221-230.
32. Katti, S. K., LeMaster, D. M. & Eklund, H. (1990) J. Mol. Biol. 212, 167-184.
33. Hellinga, H. W., Wynn, R. & Richards, F. M. (1992) Biochemistry 31, 11203-11209.
34. Hellinga, H. W. & Richards, F. M. (1991) J. Mol. Biol. 222, 763-785.
35. Benson, D. E., Wisz, M. S., Liu, W. & Hellinga, H. W. (1998) Biochemistry 37, 7070-7076.
36. Wisz, M. S., Garrett, C. Z. & Hellinga, H. W. (1998) Biochemistry 37, 8269-8277.
37. Hellinga, H. W. (1998) J. Am. Chem. Soc. 120, 10055-10066.
38. Coldren, C. D., Hellinga, H. W. & Caradonna, J. P. (1997) Proc. Natl. Acad. Sci. USA 94, 6635-6640.
39. Pinto, A. L., Hellinga, H. W. & Caradonna, J. P. (1997) Proc. Natl. Acad. Sci. USA 94, 5562-5567.
40. Nicholls, A. & Honig, B. (1991) J. Comp. Chem. 12, 435-445.
41. Bradford, M. M. (1976) Anal. Bioehem. 72, 248-254.
42. Lovenberg, W., Buchanan, B. B. & Rabinowitz, J. C. (1963) J. Biol. Chem. 238, 3899-3913.
43. Evans, P. J. & Halliwell, B. (1994) Methods Enzymol. 233, 82-92.
44. Hunt, J. B., Neece, S. H. & Ginsburg, A. (1985) Anal. Bioehem. 146, 150-157.
45. Vance, C. K. & Miller, A.-F. (1998) Biochemistry 37, 5518-5527.
46. Fultz, M. L. & Durst, R. A. (1982) Anal. Chim. Acta 140, 1-8.
47. Stankovich, M. T. (1980) Anal. Bioehem. 109, 295-308.
48. Dutton, P. L. (1978) Methods Enzymol. 54, 411-435.
49. Wilson, G. S. (1978) Methods Enzymol. 54, 396-410.
50. Bull, C., McClune, G. J. & Fee, J. A. (1983) J. Am. Chem. Soc. 105, 5290-5300.
51. Bull, C. & Fee, J. A. (1985) J. Am. Chem. Soc. 107, 3295-3304.
52. Sutherland, M. W. & Learmonth, B. A. (1997) Free Radical Res. 27, 283-289.
53. Ukeda, H., Maeda, S., Ishii, T. & Sawamura, M. (1997) Anal. Biochem. 251, 206-209.
54. Goldstein, S., Michel, C., Bors, W., Saran, M. & Czapski, G. (1988) Free Radical Biol. Med. 4, 295-303.
55. Goscin, S. A. & Fridovich, I. (1972) Arch. Biochem. Biophys. 153, 778-783.
56. Fersht, A. (1999) Enzyme Structure and Mechanism (Freeman, New York).
57. Shriver, D. F., Atkins, P. W. & Langford, C. H. (1990) Inorganic Chemistry (Freeman, New York).
58. Bull, C., Fee, J. A., O'Neill, P. & Fielden, E. M. (1982) Arch. Biochem. Biophys. 215, 551-555.
59. Getzoff, E. D., Cabelli, D. E., Fisher, C. L., Parge, H. E., Viezzoli, M. S., Banci, L. & Hallewell, R. A. (1992) Nature (London) 358, 347-350.
60. Marcus, R. A. & Sutin, N. (1985) Biochim. Biophys. Acta 811, 265-322.
61. Imlay, J. A. & Fridovich, I. (1991) J. Biol. Chem. 266, 6957-6965.
62. Starke, D. W., Chen, Y., Bapna, C. P., Lesnefsky, E. J. & Mieyal, J. J. (1997) Free Radical Biol. Med. 23, 373-384.
63. Hecht, M. H., Richardson, J. S., Richardson, D. C. & Ogden, R. C. (1990) Science 249, 884-891.
64. Quinn, T. P., Tweedy, N. B., Williams, R. W., Richardson, J. S. & Richardson, D. C. (1994) Proc. Natl. Acad. Sci. USA 91, 8747-8751.
65. Richardson, J. S., Richardson, D. C., Tweedy, N. B., Gernert, K. M., Quinn, T. P., Hecht, M. H., Erickson, B. W., Yan, Y., McClain, R. D., Donlan, M. E., et al. (1992) Biophys. J. 63, 1185-1209.