Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome protein

Journal of Biological Chemistry

Volumn 287, Issue 50, 2012, Pages 42312-42323

  Maddukuri, Leena ^a   Ketkar, Amit ^a   Eddy, Sarah ^a   Zafar, Maroof K ^a   Griffin, Wezley C ^a   Eoff, Robert L ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP HYDROLYSIS; BASE PAIRS; EXONUCLEASE; EXONUCLEASE ACTIVITY; FUNCTIONAL ASSAYS; HUMAN DNA POLYMERASE; PHYSICAL INTERACTIONS; PROTEIN-PROTEIN INTERACTIONS; PULLDOWN ASSAYS; RATE-LIMITING STEPS; WERNER SYNDROME PROTEIN;

CATALYSIS; DNA; POLYMERS;

PROTEINS;

ADENOSINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE ETA; PHOSPHODIESTERASE I; RECQ HELICASE; SPLEEN EXONUCLEASE; WERNER SYNDROME PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; GENOMIC INSTABILITY; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION; STEADY STATE;

ADENOSINE TRIPHOSPHATE; CATALYSIS; DNA; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; EXODEOXYRIBONUCLEASES; RECQ HELICASES;

EID: 84871345272     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.410332     Document Type: Article

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